Motif ID: Tead1

Z-value: 0.422


Transcription factors associated with Tead1:

Gene SymbolEntrez IDGene Name
Tead1 ENSMUSG00000055320.10 Tead1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tead1mm10_v2_chr7_+_112742025_1127420600.291.9e-01Click!


Activity profile for motif Tead1.

activity profile for motif Tead1


Sorted Z-values histogram for motif Tead1

Sorted Z-values for motif Tead1



Network of associatons between targets according to the STRING database.



First level regulatory network of Tead1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_46099752 2.073 ENSMUST00000180081.1
 Kcnj11
potassium inwardly rectifying channel, subfamily J, member 11
chr10_+_28074813 1.287 ENSMUST00000166468.1
 Ptprk
protein tyrosine phosphatase, receptor type, K
chr17_+_3397189 1.139 ENSMUST00000072156.6
 Tiam2
T cell lymphoma invasion and metastasis 2
chr11_-_100970887 1.089 ENSMUST00000060792.5
 Ptrf
polymerase I and transcript release factor
chr4_-_43558386 0.991 ENSMUST00000130353.1
 Tln1
talin 1
chr11_-_32222233 0.846 ENSMUST00000150381.1
ENSMUST00000144902.1
ENSMUST00000020524.8
 Rhbdf1


rhomboid family 1 (Drosophila)


chr19_-_57197377 0.766 ENSMUST00000111546.1
 Ablim1
actin-binding LIM protein 1
chr17_+_86167777 0.736 ENSMUST00000097275.2
 Prkce
protein kinase C, epsilon
chr19_-_57197435 0.728 ENSMUST00000111550.1
 Ablim1
actin-binding LIM protein 1
chr19_-_57197496 0.728 ENSMUST00000111544.1
 Ablim1
actin-binding LIM protein 1
chr8_-_105966038 0.685 ENSMUST00000116429.2
ENSMUST00000034370.9
 Slc12a4

solute carrier family 12, member 4

chr19_-_57197556 0.671 ENSMUST00000099294.2
 Ablim1
actin-binding LIM protein 1
chr2_+_19658055 0.668 ENSMUST00000052168.4
 Otud1
OTU domain containing 1
chr4_-_120287349 0.655 ENSMUST00000102656.3
 Foxo6
forkhead box O6
chr1_-_87394721 0.635 ENSMUST00000113212.3
 Kcnj13
potassium inwardly-rectifying channel, subfamily J, member 13
chr16_+_43363855 0.627 ENSMUST00000156367.1
 Zbtb20
zinc finger and BTB domain containing 20
chr6_+_17306335 0.595 ENSMUST00000007799.6
ENSMUST00000115456.1
ENSMUST00000115455.2
ENSMUST00000130505.1
 Cav1



caveolin 1, caveolae protein



chr6_-_128124312 0.593 ENSMUST00000127105.1
 Tspan9
tetraspanin 9
chr10_-_42276688 0.576 ENSMUST00000175881.1
ENSMUST00000056974.3
 Foxo3

forkhead box O3

chr2_+_156775409 0.571 ENSMUST00000088552.6
 Myl9
myosin, light polypeptide 9, regulatory
chr7_-_34133215 0.517 ENSMUST00000038537.8
 Wtip
WT1-interacting protein
chr5_+_24426831 0.497 ENSMUST00000155598.1
 Slc4a2
solute carrier family 4 (anion exchanger), member 2
chr12_-_86988676 0.470 ENSMUST00000095521.2
 Zdhhc22
zinc finger, DHHC-type containing 22
chr6_+_88724667 0.394 ENSMUST00000163271.1
 Mgll
monoglyceride lipase
chr15_+_78842632 0.385 ENSMUST00000059619.1
 Cdc42ep1
CDC42 effector protein (Rho GTPase binding) 1
chr6_-_120364344 0.376 ENSMUST00000146667.1
 Ccdc77
coiled-coil domain containing 77
chr6_+_88724828 0.362 ENSMUST00000089449.2
 Mgll
monoglyceride lipase
chr19_-_42128982 0.345 ENSMUST00000161873.1
 Avpi1
arginine vasopressin-induced 1
chr19_-_4439388 0.323 ENSMUST00000117462.1
ENSMUST00000048197.3
 Rhod

ras homolog gene family, member D

chr14_+_70577839 0.307 ENSMUST00000089049.2
 Nudt18
nudix (nucleoside diphosphate linked moiety X)-type motif 18
chr4_+_43267165 0.287 ENSMUST00000107942.2
ENSMUST00000102953.3
 Atp8b5

ATPase, class I, type 8B, member 5

chr15_+_6386598 0.285 ENSMUST00000080880.5
ENSMUST00000110664.2
ENSMUST00000110663.2
ENSMUST00000161812.1
ENSMUST00000160134.1
 Dab2




disabled 2, mitogen-responsive phosphoprotein




chr10_+_24595623 0.280 ENSMUST00000176228.1
ENSMUST00000129142.1
 Ctgf

connective tissue growth factor

chr16_+_43364145 0.272 ENSMUST00000148775.1
 Zbtb20
zinc finger and BTB domain containing 20
chr4_-_62360524 0.270 ENSMUST00000107461.1
ENSMUST00000084528.3
 Fkbp15

FK506 binding protein 15

chr13_+_112464070 0.270 ENSMUST00000183663.1
ENSMUST00000184311.1
ENSMUST00000183886.1
 Il6st


interleukin 6 signal transducer


chr16_-_4559720 0.268 ENSMUST00000005862.7
 Tfap4
transcription factor AP4
chr8_-_122551316 0.258 ENSMUST00000067252.7
 Piezo1
piezo-type mechanosensitive ion channel component 1
chr17_-_47834682 0.251 ENSMUST00000066368.6
 Mdfi
MyoD family inhibitor
chr19_+_33822908 0.251 ENSMUST00000042061.6
 Gm5519
predicted pseudogene 5519
chr11_-_115933464 0.248 ENSMUST00000021097.3
 Recql5
RecQ protein-like 5
chr4_+_152297205 0.245 ENSMUST00000048892.7
 Icmt
isoprenylcysteine carboxyl methyltransferase
chr4_-_47057296 0.240 ENSMUST00000107747.1
ENSMUST00000084616.2
 Anks6

ankyrin repeat and sterile alpha motif domain containing 6

chr5_-_24601961 0.239 ENSMUST00000030791.7
 Smarcd3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr5_+_117363513 0.236 ENSMUST00000111959.1
 Wsb2
WD repeat and SOCS box-containing 2
chr7_+_24904384 0.226 ENSMUST00000117419.1
 Arhgef1
Rho guanine nucleotide exchange factor (GEF) 1
chr10_+_126978690 0.224 ENSMUST00000105256.2
 Ctdsp2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr10_-_42276744 0.224 ENSMUST00000105502.1
ENSMUST00000105501.1
 Foxo3

forkhead box O3

chr13_-_74376566 0.219 ENSMUST00000091481.2
 Zfp72
zinc finger protein 72
chr4_-_62360436 0.217 ENSMUST00000084527.3
ENSMUST00000098033.3
 Fkbp15

FK506 binding protein 15

chr1_-_168432270 0.204 ENSMUST00000072863.4
 Pbx1
pre B cell leukemia homeobox 1
chr13_-_34077992 0.177 ENSMUST00000056427.8
 Tubb2a
tubulin, beta 2A class IIA
chr11_+_115933282 0.172 ENSMUST00000140991.1
 Sap30bp
SAP30 binding protein
chr6_+_145934113 0.165 ENSMUST00000032383.7
 Sspn
sarcospan
chr17_-_24209377 0.163 ENSMUST00000024931.4
 Ntn3
netrin 3
chr7_-_109616548 0.163 ENSMUST00000077909.1
ENSMUST00000084738.3
 St5

suppression of tumorigenicity 5

chrX_-_73869804 0.160 ENSMUST00000066576.5
ENSMUST00000114430.1
 L1cam

L1 cell adhesion molecule

chr2_+_20519776 0.147 ENSMUST00000114604.2
ENSMUST00000066509.3
 Etl4

enhancer trap locus 4

chr2_-_164857542 0.144 ENSMUST00000109316.1
ENSMUST00000156255.1
ENSMUST00000128110.1
ENSMUST00000109317.3
 Pltp



phospholipid transfer protein



chr4_+_149545102 0.142 ENSMUST00000105692.1
 Ctnnbip1
catenin beta interacting protein 1
chr4_+_115828061 0.141 ENSMUST00000030477.3
 Mob3c
MOB kinase activator 3C
chr6_-_37442095 0.140 ENSMUST00000041093.5
 Creb3l2
cAMP responsive element binding protein 3-like 2
chrX_+_101254528 0.137 ENSMUST00000062000.4
 Foxo4
forkhead box O4
chr10_+_24595434 0.115 ENSMUST00000020171.5
 Ctgf
connective tissue growth factor
chr16_-_34262830 0.111 ENSMUST00000114947.1
 Kalrn
kalirin, RhoGEF kinase
chr11_-_5381734 0.110 ENSMUST00000172492.1
 Znrf3
zinc and ring finger 3
chr8_-_70302487 0.105 ENSMUST00000008004.9
 Ddx49
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
chr6_+_17306415 0.101 ENSMUST00000150901.1
 Cav1
caveolin 1, caveolae protein
chr7_-_90129339 0.099 ENSMUST00000181189.1
 2310010J17Rik
RIKEN cDNA 2310010J17 gene
chr2_-_168230575 0.098 ENSMUST00000109193.1
 Dpm1
dolichol-phosphate (beta-D) mannosyltransferase 1
chr2_+_91457501 0.097 ENSMUST00000028689.3
 Lrp4
low density lipoprotein receptor-related protein 4
chr3_-_57575760 0.097 ENSMUST00000029380.7
 Wwtr1
WW domain containing transcription regulator 1
chr1_+_51289106 0.096 ENSMUST00000051572.6
 Sdpr
serum deprivation response
chr4_+_62360695 0.096 ENSMUST00000084526.5
 Slc31a1
solute carrier family 31, member 1
chr8_-_70700070 0.090 ENSMUST00000116172.1
 Gm11175
predicted gene 11175
chr13_+_65512678 0.085 ENSMUST00000081471.2
 Gm10139
predicted gene 10139
chr19_-_42129043 0.083 ENSMUST00000018965.3
 Avpi1
arginine vasopressin-induced 1
chr14_-_122913751 0.081 ENSMUST00000160401.1
 Ggact
gamma-glutamylamine cyclotransferase
chr18_+_60526194 0.080 ENSMUST00000025505.5
 Dctn4
dynactin 4
chr9_-_44713196 0.076 ENSMUST00000144251.1
ENSMUST00000156918.1
 Phldb1

pleckstrin homology-like domain, family B, member 1

chr18_+_82554463 0.075 ENSMUST00000062446.7
ENSMUST00000102812.4
ENSMUST00000075372.5
ENSMUST00000080658.4
ENSMUST00000152071.1
ENSMUST00000114674.3
ENSMUST00000142850.1
ENSMUST00000133193.1
ENSMUST00000123251.1
ENSMUST00000153478.1
ENSMUST00000132369.1
 Mbp










myelin basic protein










chr11_+_70700473 0.073 ENSMUST00000152618.2
ENSMUST00000102554.1
ENSMUST00000094499.4
ENSMUST00000072187.5
 Kif1c



kinesin family member 1C



chr2_-_32712728 0.071 ENSMUST00000009699.9
 Cdk9
cyclin-dependent kinase 9 (CDC2-related kinase)
chr3_+_96104498 0.060 ENSMUST00000132980.1
ENSMUST00000138206.1
ENSMUST00000090785.2
ENSMUST00000035519.5
 Otud7b



OTU domain containing 7B



chr8_+_70302518 0.051 ENSMUST00000066469.7
 Cope
coatomer protein complex, subunit epsilon
chr16_-_34262945 0.049 ENSMUST00000114953.1
 Kalrn
kalirin, RhoGEF kinase
chr9_-_16378231 0.048 ENSMUST00000082170.5
 Fat3
FAT tumor suppressor homolog 3 (Drosophila)
chr11_+_120721452 0.046 ENSMUST00000018156.5
 Rac3
RAS-related C3 botulinum substrate 3
chr9_-_95750335 0.039 ENSMUST00000053785.3
 Trpc1
transient receptor potential cation channel, subfamily C, member 1
chr16_+_91225550 0.037 ENSMUST00000035608.8
 Olig2
oligodendrocyte transcription factor 2
chr9_-_96752822 0.036 ENSMUST00000152594.1
 Zbtb38
zinc finger and BTB domain containing 38
chr2_-_175131864 0.031 ENSMUST00000108929.2
 Gm14399
predicted gene 14399
chr7_-_28372494 0.027 ENSMUST00000119990.1
 Plekhg2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chrX_+_152178945 0.026 ENSMUST00000096275.4
 Iqsec2
IQ motif and Sec7 domain 2
chr9_+_107299152 0.023 ENSMUST00000171568.1
 Cish
cytokine inducible SH2-containing protein
chr11_+_70700606 0.021 ENSMUST00000137119.2
 Kif1c
kinesin family member 1C
chr8_+_70302761 0.018 ENSMUST00000150968.1
 Cope
coatomer protein complex, subunit epsilon
chr9_-_8004585 0.016 ENSMUST00000086580.5
ENSMUST00000065353.6
 Yap1

yes-associated protein 1

chr6_+_17307040 0.016 ENSMUST00000123439.1
 Cav1
caveolin 1, caveolae protein
chr11_+_70432627 0.015 ENSMUST00000084954.6
ENSMUST00000108568.3
ENSMUST00000079056.2
ENSMUST00000102564.4
ENSMUST00000124943.1
ENSMUST00000150076.1
ENSMUST00000102563.1
 Arrb2






arrestin, beta 2






chr16_-_97851796 0.014 ENSMUST00000121584.1
 Prdm15
PR domain containing 15
chr6_-_134566913 0.007 ENSMUST00000032322.8
 Lrp6
low density lipoprotein receptor-related protein 6
chr10_-_127288851 0.007 ENSMUST00000156208.1
ENSMUST00000026476.6
 Mbd6

methyl-CpG binding domain protein 6

chr14_-_61556746 0.003 ENSMUST00000100496.4
 Spryd7
SPRY domain containing 7

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.2 1.1 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361) termination of RNA polymerase I transcription(GO:0006363)
0.1 0.7 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085)
0.1 0.4 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.1 1.0 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.1 1.3 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.1 0.8 GO:1905206 positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) positive regulation of hydrogen peroxide-induced cell death(GO:1905206)
0.1 0.8 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.3 GO:0009182 purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) dGDP metabolic process(GO:0046066) GDP metabolic process(GO:0046710)
0.1 2.6 GO:0010107 potassium ion import(GO:0010107)
0.1 0.3 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165) regulation of interleukin-6-mediated signaling pathway(GO:0070103) negative regulation of interleukin-6-mediated signaling pathway(GO:0070104)
0.1 0.3 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 0.2 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.1 0.2 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.1 0.2 GO:0006481 C-terminal protein methylation(GO:0006481)
0.1 0.3 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.0 0.3 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.0 0.1 GO:0042360 vitamin E metabolic process(GO:0042360)
0.0 0.1 GO:1904395 regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.0 0.4 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.2 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0 2.8 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.1 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.0 0.1 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.7 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.5 GO:2000637 positive regulation of gene silencing by miRNA(GO:2000637)
0.0 0.2 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.1 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.2 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.1 GO:1902416 positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216)
0.0 0.5 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.1 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0 0.8 GO:0042058 regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
0.0 0.1 GO:0019673 GDP-mannose metabolic process(GO:0019673)
0.0 0.3 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.9 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.3 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 0.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.7 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.6 GO:0043196 varicosity(GO:0043196)
0.0 0.5 GO:0016460 myosin II complex(GO:0016460)
0.0 2.9 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.1 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 1.3 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.2 GO:0071564 npBAF complex(GO:0071564)
0.0 1.3 GO:0005901 caveola(GO:0005901)
0.0 0.2 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.2 0.7 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.2 1.1 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 0.7 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.1 0.7 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 1.0 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.3 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923) oncostatin-M receptor activity(GO:0004924)
0.1 0.8 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.6 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 1.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.2 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.6 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.2 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.3 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.1 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.5 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 0.9 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 0.1 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.5 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.0 0.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.0 GO:0031762 alpha-1A adrenergic receptor binding(GO:0031691) alpha-1B adrenergic receptor binding(GO:0031692) follicle-stimulating hormone receptor binding(GO:0031762)
0.0 0.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 1.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.1 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)