Motif ID: Tead1

Z-value: 0.422


Transcription factors associated with Tead1:

Gene SymbolEntrez IDGene Name
Tead1 ENSMUSG00000055320.10 Tead1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tead1mm10_v2_chr7_+_112742025_1127420600.291.9e-01Click!


Activity profile for motif Tead1.

activity profile for motif Tead1


Sorted Z-values histogram for motif Tead1

Sorted Z-values for motif Tead1



Network of associatons between targets according to the STRING database.



First level regulatory network of Tead1

PNG image of the network

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Top targets:


Showing 1 to 20 of 104 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_46099752 2.073 ENSMUST00000180081.1
 Kcnj11
potassium inwardly rectifying channel, subfamily J, member 11
chr10_+_28074813 1.287 ENSMUST00000166468.1
 Ptprk
protein tyrosine phosphatase, receptor type, K
chr17_+_3397189 1.139 ENSMUST00000072156.6
 Tiam2
T cell lymphoma invasion and metastasis 2
chr11_-_100970887 1.089 ENSMUST00000060792.5
 Ptrf
polymerase I and transcript release factor
chr4_-_43558386 0.991 ENSMUST00000130353.1
 Tln1
talin 1
chr11_-_32222233 0.846 ENSMUST00000150381.1
ENSMUST00000144902.1
ENSMUST00000020524.8
 Rhbdf1


rhomboid family 1 (Drosophila)


chr19_-_57197377 0.766 ENSMUST00000111546.1
 Ablim1
actin-binding LIM protein 1
chr17_+_86167777 0.736 ENSMUST00000097275.2
 Prkce
protein kinase C, epsilon
chr19_-_57197435 0.728 ENSMUST00000111550.1
 Ablim1
actin-binding LIM protein 1
chr19_-_57197496 0.728 ENSMUST00000111544.1
 Ablim1
actin-binding LIM protein 1
chr8_-_105966038 0.685 ENSMUST00000116429.2
ENSMUST00000034370.9
 Slc12a4

solute carrier family 12, member 4

chr19_-_57197556 0.671 ENSMUST00000099294.2
 Ablim1
actin-binding LIM protein 1
chr2_+_19658055 0.668 ENSMUST00000052168.4
 Otud1
OTU domain containing 1
chr4_-_120287349 0.655 ENSMUST00000102656.3
 Foxo6
forkhead box O6
chr1_-_87394721 0.635 ENSMUST00000113212.3
 Kcnj13
potassium inwardly-rectifying channel, subfamily J, member 13
chr16_+_43363855 0.627 ENSMUST00000156367.1
 Zbtb20
zinc finger and BTB domain containing 20
chr6_+_17306335 0.595 ENSMUST00000007799.6
ENSMUST00000115456.1
ENSMUST00000115455.2
ENSMUST00000130505.1
 Cav1



caveolin 1, caveolae protein



chr6_-_128124312 0.593 ENSMUST00000127105.1
 Tspan9
tetraspanin 9
chr10_-_42276688 0.576 ENSMUST00000175881.1
ENSMUST00000056974.3
 Foxo3

forkhead box O3

chr2_+_156775409 0.571 ENSMUST00000088552.6
 Myl9
myosin, light polypeptide 9, regulatory

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 37 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.8 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 2.6 GO:0010107 potassium ion import(GO:0010107)
0.1 1.3 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.2 1.1 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361) termination of RNA polymerase I transcription(GO:0006363)
0.1 1.0 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.9 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.1 0.8 GO:1905206 positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) positive regulation of hydrogen peroxide-induced cell death(GO:1905206)
0.1 0.8 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.8 GO:0042058 regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
0.2 0.7 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.1 0.7 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085)
0.0 0.7 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.5 GO:2000637 positive regulation of gene silencing by miRNA(GO:2000637)
0.0 0.5 GO:0018345 protein palmitoylation(GO:0018345)
0.1 0.4 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.0 0.4 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.1 0.3 GO:0009182 purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) dGDP metabolic process(GO:0046066) GDP metabolic process(GO:0046710)
0.1 0.3 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165) regulation of interleukin-6-mediated signaling pathway(GO:0070103) negative regulation of interleukin-6-mediated signaling pathway(GO:0070104)
0.1 0.3 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 0.3 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)

Gene overrepresentation in cellular_component category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.9 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.7 2.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 1.3 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 1.3 GO:0005901 caveola(GO:0005901)
0.0 0.7 GO:0002080 acrosomal membrane(GO:0002080)
0.1 0.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.6 GO:0043196 varicosity(GO:0043196)
0.0 0.5 GO:0016460 myosin II complex(GO:0016460)
0.1 0.3 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.2 GO:0071564 npBAF complex(GO:0071564)
0.0 0.2 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.1 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 29 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 2.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 1.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 1.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.2 1.1 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 1.0 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.9 GO:0001221 transcription cofactor binding(GO:0001221)
0.1 0.8 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.2 0.7 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 0.7 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.1 0.7 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.6 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.6 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.5 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 0.5 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.0 0.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 0.3 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923) oncostatin-M receptor activity(GO:0004924)
0.0 0.3 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)