Motif ID: Rorc_Nr1d1

Z-value: 0.491

Transcription factors associated with Rorc_Nr1d1:

Gene SymbolEntrez IDGene Name
Nr1d1 ENSMUSG00000020889.11 Nr1d1
Rorc ENSMUSG00000028150.8 Rorc

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rorcmm10_v2_chr3_+_94372794_94372872-0.223.2e-01Click!
Nr1d1mm10_v2_chr11_-_98775333_98775354-0.077.4e-01Click!


Activity profile for motif Rorc_Nr1d1.

activity profile for motif Rorc_Nr1d1


Sorted Z-values histogram for motif Rorc_Nr1d1

Sorted Z-values for motif Rorc_Nr1d1



Network of associatons between targets according to the STRING database.



First level regulatory network of Rorc_Nr1d1

PNG image of the network

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Top targets:


Showing 1 to 20 of 117 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_79386943 3.143 ENSMUST00000053718.8
ENSMUST00000179243.1
 Rlbp1

retinaldehyde binding protein 1

chr1_-_14310198 1.338 ENSMUST00000168081.2
ENSMUST00000027066.6
 Eya1

eyes absent 1 homolog (Drosophila)

chr7_+_113207465 1.267 ENSMUST00000047321.7
 Arntl
aryl hydrocarbon receptor nuclear translocator-like
chr12_-_34528844 1.264 ENSMUST00000110819.2
 Hdac9
histone deacetylase 9
chrX_+_103422010 1.215 ENSMUST00000182089.1
 Gm26992
predicted gene, 26992
chr7_+_45705088 0.854 ENSMUST00000080885.3
 Dbp
D site albumin promoter binding protein
chr5_+_64803513 0.782 ENSMUST00000165536.1
 Klf3
Kruppel-like factor 3 (basic)
chr15_-_50882806 0.766 ENSMUST00000184885.1
 Trps1
trichorhinophalangeal syndrome I (human)
chr7_-_142661305 0.723 ENSMUST00000105936.1
 Igf2
insulin-like growth factor 2
chr15_-_66801577 0.629 ENSMUST00000168589.1
 Sla
src-like adaptor
chr10_+_57784859 0.621 ENSMUST00000020024.5
 Fabp7
fatty acid binding protein 7, brain
chr7_-_134232125 0.620 ENSMUST00000127524.1
 Adam12
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr10_+_106470281 0.607 ENSMUST00000029404.9
ENSMUST00000169303.1
 Ppfia2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chr15_-_65014904 0.591 ENSMUST00000110100.2
 Gm21961
predicted gene, 21961
chr15_+_62037986 0.586 ENSMUST00000182956.1
ENSMUST00000182075.1
ENSMUST00000180432.2
ENSMUST00000181416.2
ENSMUST00000181657.2
 Pvt1




plasmacytoma variant translocation 1




chr3_-_84304762 0.578 ENSMUST00000107692.1
 Trim2
tripartite motif-containing 2
chr16_-_37384915 0.533 ENSMUST00000114787.1
ENSMUST00000114782.1
ENSMUST00000023526.2
ENSMUST00000114775.1
 Stxbp5l



syntaxin binding protein 5-like



chr11_-_98329641 0.531 ENSMUST00000041685.6
 Neurod2
neurogenic differentiation 2
chr3_-_89764581 0.531 ENSMUST00000029562.3
 Chrnb2
cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)
chr2_+_4389614 0.484 ENSMUST00000115037.2
 Frmd4a
FERM domain containing 4A

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.6 GO:0007601 visual perception(GO:0007601)
0.2 1.6 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.4 1.3 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.2 1.3 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 1.1 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 1.0 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.8 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.6 GO:0060134 prepulse inhibition(GO:0060134)
0.2 0.5 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.2 0.5 GO:0060084 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) synaptic transmission involved in micturition(GO:0060084)
0.0 0.5 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.5 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.4 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 0.3 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.0 0.3 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.3 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 0.3 GO:0048305 immunoglobulin secretion(GO:0048305)
0.1 0.2 GO:0033860 regulation of NAD(P)H oxidase activity(GO:0033860)
0.0 0.2 GO:0043206 extracellular fibril organization(GO:0043206)
0.0 0.2 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)

Gene overrepresentation in cellular_component category:

Showing 1 to 6 of 6 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.3 GO:0033391 chromatoid body(GO:0033391)
0.0 1.3 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 1.0 GO:0031201 SNARE complex(GO:0031201)
0.0 0.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)

Gene overrepresentation in molecular_function category:

Showing 1 to 19 of 19 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 3.1 GO:0019841 retinol binding(GO:0019841)
0.0 1.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.4 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.3 1.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 1.3 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 1.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.8 GO:0017022 myosin binding(GO:0017022)
0.0 0.6 GO:0005504 fatty acid binding(GO:0005504)
0.2 0.5 GO:0004658 propionyl-CoA carboxylase activity(GO:0004658)
0.0 0.5 GO:0042166 acetylcholine binding(GO:0042166)
0.0 0.5 GO:0070888 E-box binding(GO:0070888)
0.0 0.5 GO:0043531 ADP binding(GO:0043531)
0.1 0.3 GO:0018121 imidazoleglycerol-phosphate synthase activity(GO:0000107) NAD(P)-cysteine ADP-ribosyltransferase activity(GO:0018071) NAD(P)-asparagine ADP-ribosyltransferase activity(GO:0018121) NAD(P)-serine ADP-ribosyltransferase activity(GO:0018127) 7-cyano-7-deazaguanine tRNA-ribosyltransferase activity(GO:0043867) purine deoxyribosyltransferase activity(GO:0044102)
0.0 0.2 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.1 GO:0019863 IgE binding(GO:0019863)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.0 GO:0031752 D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752)