Motif ID: Rorc_Nr1d1
Z-value: 0.491
Transcription factors associated with Rorc_Nr1d1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Nr1d1 | ENSMUSG00000020889.11 | Nr1d1 |
Rorc | ENSMUSG00000028150.8 | Rorc |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Rorc | mm10_v2_chr3_+_94372794_94372872 | -0.22 | 3.2e-01 | Click! |
Nr1d1 | mm10_v2_chr11_-_98775333_98775354 | -0.07 | 7.4e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 1.3 | GO:0090403 | oxidative stress-induced premature senescence(GO:0090403) |
0.2 | 1.3 | GO:0072513 | positive regulation of secondary heart field cardioblast proliferation(GO:0072513) |
0.2 | 0.5 | GO:2000297 | negative regulation of synapse maturation(GO:2000297) |
0.2 | 0.5 | GO:0060084 | regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) synaptic transmission involved in micturition(GO:0060084) |
0.2 | 1.6 | GO:0034983 | peptidyl-lysine deacetylation(GO:0034983) |
0.1 | 1.1 | GO:0038028 | insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) |
0.1 | 0.3 | GO:0038163 | thrombopoietin-mediated signaling pathway(GO:0038163) |
0.1 | 0.1 | GO:0007113 | endomitotic cell cycle(GO:0007113) |
0.1 | 0.2 | GO:0033860 | regulation of NAD(P)H oxidase activity(GO:0033860) |
0.0 | 0.1 | GO:0050859 | regulation of activation of Janus kinase activity(GO:0010533) regulation of activation of JAK2 kinase activity(GO:0010534) negative regulation of serotonin secretion(GO:0014063) negative regulation of B cell receptor signaling pathway(GO:0050859) regulation of eosinophil activation(GO:1902566) negative regulation of membrane invagination(GO:1905154) |
0.0 | 0.1 | GO:0002925 | positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925) |
0.0 | 0.1 | GO:0031627 | telomeric loop formation(GO:0031627) |
0.0 | 0.6 | GO:0060134 | prepulse inhibition(GO:0060134) |
0.0 | 0.8 | GO:1902043 | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043) |
0.0 | 2.6 | GO:0007601 | visual perception(GO:0007601) |
0.0 | 0.5 | GO:0006744 | ubiquinone biosynthetic process(GO:0006744) |
0.0 | 0.1 | GO:0014053 | negative regulation of gamma-aminobutyric acid secretion(GO:0014053) |
0.0 | 0.0 | GO:1904995 | negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995) |
0.0 | 1.0 | GO:0046676 | negative regulation of insulin secretion(GO:0046676) |
0.0 | 0.2 | GO:0043206 | extracellular fibril organization(GO:0043206) |
0.0 | 0.3 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
0.0 | 0.1 | GO:0035752 | lysosomal lumen pH elevation(GO:0035752) |
0.0 | 0.3 | GO:0050901 | leukocyte tethering or rolling(GO:0050901) |
0.0 | 0.3 | GO:0048305 | immunoglobulin secretion(GO:0048305) |
0.0 | 0.2 | GO:0035887 | aortic smooth muscle cell differentiation(GO:0035887) |
0.0 | 0.1 | GO:2000194 | regulation of female gonad development(GO:2000194) |
0.0 | 0.0 | GO:0007621 | negative regulation of female receptivity(GO:0007621) |
0.0 | 0.2 | GO:0033572 | transferrin transport(GO:0033572) |
0.0 | 0.4 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
0.0 | 0.1 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
0.0 | 0.1 | GO:0006102 | isocitrate metabolic process(GO:0006102) |
0.0 | 0.5 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
0.0 | 0.0 | GO:0002741 | positive regulation of cytokine secretion involved in immune response(GO:0002741) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 1.3 | GO:0033391 | chromatoid body(GO:0033391) |
0.0 | 0.5 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
0.0 | 0.1 | GO:0038039 | G-protein coupled receptor heterodimeric complex(GO:0038039) |
0.0 | 1.0 | GO:0031201 | SNARE complex(GO:0031201) |
0.0 | 0.1 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
0.0 | 1.3 | GO:0035097 | histone methyltransferase complex(GO:0035097) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 3.1 | GO:0019841 | retinol binding(GO:0019841) |
0.3 | 1.3 | GO:0017162 | aryl hydrocarbon receptor binding(GO:0017162) |
0.2 | 0.5 | GO:0004658 | propionyl-CoA carboxylase activity(GO:0004658) |
0.1 | 0.3 | GO:0018121 | imidazoleglycerol-phosphate synthase activity(GO:0000107) NAD(P)-cysteine ADP-ribosyltransferase activity(GO:0018071) NAD(P)-asparagine ADP-ribosyltransferase activity(GO:0018121) NAD(P)-serine ADP-ribosyltransferase activity(GO:0018127) 7-cyano-7-deazaguanine tRNA-ribosyltransferase activity(GO:0043867) purine deoxyribosyltransferase activity(GO:0044102) |
0.1 | 1.3 | GO:0031078 | histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) |
0.0 | 1.1 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
0.0 | 0.5 | GO:0042166 | acetylcholine binding(GO:0042166) |
0.0 | 0.1 | GO:0019863 | IgE binding(GO:0019863) |
0.0 | 0.1 | GO:0004965 | G-protein coupled GABA receptor activity(GO:0004965) |
0.0 | 0.1 | GO:0008429 | phosphatidylethanolamine binding(GO:0008429) |
0.0 | 0.0 | GO:0031752 | D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752) |
0.0 | 1.4 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
0.0 | 0.1 | GO:0035312 | 5'-3' exodeoxyribonuclease activity(GO:0035312) |
0.0 | 0.6 | GO:0005504 | fatty acid binding(GO:0005504) |
0.0 | 0.5 | GO:0070888 | E-box binding(GO:0070888) |
0.0 | 0.8 | GO:0017022 | myosin binding(GO:0017022) |
0.0 | 1.4 | GO:0004725 | protein tyrosine phosphatase activity(GO:0004725) |
0.0 | 0.2 | GO:0016805 | dipeptidase activity(GO:0016805) |
0.0 | 0.5 | GO:0043531 | ADP binding(GO:0043531) |