Motif ID: Rorc_Nr1d1

Z-value: 0.491

Transcription factors associated with Rorc_Nr1d1:

Gene SymbolEntrez IDGene Name
Nr1d1 ENSMUSG00000020889.11 Nr1d1
Rorc ENSMUSG00000028150.8 Rorc

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rorcmm10_v2_chr3_+_94372794_94372872-0.223.2e-01Click!
Nr1d1mm10_v2_chr11_-_98775333_98775354-0.077.4e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Rorc_Nr1d1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_79386943 3.143 ENSMUST00000053718.8
ENSMUST00000179243.1
Rlbp1

retinaldehyde binding protein 1

chr1_-_14310198 1.338 ENSMUST00000168081.2
ENSMUST00000027066.6
Eya1

eyes absent 1 homolog (Drosophila)

chr7_+_113207465 1.267 ENSMUST00000047321.7
Arntl
aryl hydrocarbon receptor nuclear translocator-like
chr12_-_34528844 1.264 ENSMUST00000110819.2
Hdac9
histone deacetylase 9
chrX_+_103422010 1.215 ENSMUST00000182089.1
Gm26992
predicted gene, 26992
chr7_+_45705088 0.854 ENSMUST00000080885.3
Dbp
D site albumin promoter binding protein
chr5_+_64803513 0.782 ENSMUST00000165536.1
Klf3
Kruppel-like factor 3 (basic)
chr15_-_50882806 0.766 ENSMUST00000184885.1
Trps1
trichorhinophalangeal syndrome I (human)
chr7_-_142661305 0.723 ENSMUST00000105936.1
Igf2
insulin-like growth factor 2
chr15_-_66801577 0.629 ENSMUST00000168589.1
Sla
src-like adaptor
chr10_+_57784859 0.621 ENSMUST00000020024.5
Fabp7
fatty acid binding protein 7, brain
chr7_-_134232125 0.620 ENSMUST00000127524.1
Adam12
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr10_+_106470281 0.607 ENSMUST00000029404.9
ENSMUST00000169303.1
Ppfia2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chr15_-_65014904 0.591 ENSMUST00000110100.2
Gm21961
predicted gene, 21961
chr15_+_62037986 0.586 ENSMUST00000182956.1
ENSMUST00000182075.1
ENSMUST00000180432.2
ENSMUST00000181416.2
ENSMUST00000181657.2
Pvt1




plasmacytoma variant translocation 1




chr3_-_84304762 0.578 ENSMUST00000107692.1
Trim2
tripartite motif-containing 2
chr16_-_37384915 0.533 ENSMUST00000114787.1
ENSMUST00000114782.1
ENSMUST00000023526.2
ENSMUST00000114775.1
Stxbp5l



syntaxin binding protein 5-like



chr11_-_98329641 0.531 ENSMUST00000041685.6
Neurod2
neurogenic differentiation 2
chr3_-_89764581 0.531 ENSMUST00000029562.3
Chrnb2
cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)
chr2_+_4389614 0.484 ENSMUST00000115037.2
Frmd4a
FERM domain containing 4A
chr7_-_134232005 0.475 ENSMUST00000134504.1
Adam12
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr1_-_180193475 0.470 ENSMUST00000160482.1
ENSMUST00000170472.1
Adck3

aarF domain containing kinase 3

chr7_-_126922887 0.451 ENSMUST00000134134.1
ENSMUST00000119781.1
ENSMUST00000121612.2
Tmem219


transmembrane protein 219


chr16_-_37384940 0.433 ENSMUST00000114781.1
ENSMUST00000114780.1
Stxbp5l

syntaxin binding protein 5-like

chr8_+_119862239 0.423 ENSMUST00000034287.8
Klhl36
kelch-like 36
chr7_-_142661858 0.377 ENSMUST00000145896.2
Igf2
insulin-like growth factor 2
chr11_-_84069179 0.374 ENSMUST00000138208.1
Dusp14
dual specificity phosphatase 14
chr6_+_65778988 0.352 ENSMUST00000031976.7
ENSMUST00000081219.7
ENSMUST00000031973.6
ENSMUST00000172638.1
Prdm5



PR domain containing 5



chr5_-_123141067 0.311 ENSMUST00000162697.1
ENSMUST00000160321.1
ENSMUST00000159637.1
AI480526


expressed sequence AI480526


chr10_+_39612934 0.310 ENSMUST00000019987.6
Traf3ip2
TRAF3 interacting protein 2
chr13_+_6548154 0.308 ENSMUST00000021611.8
Pitrm1
pitrilysin metallepetidase 1
chr16_-_20730544 0.291 ENSMUST00000076422.5
Thpo
thrombopoietin
chr5_-_115484297 0.290 ENSMUST00000112067.1
Sirt4
sirtuin 4
chr17_-_51810866 0.278 ENSMUST00000176669.1
Satb1
special AT-rich sequence binding protein 1
chr6_-_88874045 0.261 ENSMUST00000038409.5
Podxl2
podocalyxin-like 2
chr11_+_94327984 0.258 ENSMUST00000107818.2
ENSMUST00000051221.6
Ankrd40

ankyrin repeat domain 40

chr5_+_64970069 0.257 ENSMUST00000031080.8
Fam114a1
family with sequence similarity 114, member A1
chr1_+_151344472 0.254 ENSMUST00000023918.6
ENSMUST00000097543.1
ENSMUST00000111887.3
Ivns1abp


influenza virus NS1A binding protein


chr9_-_101034857 0.251 ENSMUST00000142676.1
ENSMUST00000149322.1
Pccb

propionyl Coenzyme A carboxylase, beta polypeptide

chr4_+_54945038 0.241 ENSMUST00000133895.1
Zfp462
zinc finger protein 462
chr6_+_134830145 0.211 ENSMUST00000046303.5
Crebl2
cAMP responsive element binding protein-like 2
chr4_+_98546919 0.205 ENSMUST00000030290.7
Inadl
InaD-like (Drosophila)
chr9_-_101034892 0.203 ENSMUST00000035116.5
Pccb
propionyl Coenzyme A carboxylase, beta polypeptide
chr12_-_84876479 0.195 ENSMUST00000163189.1
ENSMUST00000110254.2
ENSMUST00000002073.6
Ltbp2


latent transforming growth factor beta binding protein 2


chr12_-_100159601 0.188 ENSMUST00000021596.7
Nrde2
nrde-2 necessary for RNA interference, domain containing
chr5_+_144100387 0.184 ENSMUST00000041804.7
Lmtk2
lemur tyrosine kinase 2
chr6_+_29361410 0.163 ENSMUST00000156163.1
Calu
calumenin
chr7_+_46033698 0.163 ENSMUST00000033121.6
Nomo1
nodal modulator 1
chr1_-_172590463 0.158 ENSMUST00000065679.6
Slamf8
SLAM family member 8
chr8_-_85080652 0.154 ENSMUST00000152785.1
Wdr83
WD repeat domain containing 83
chr9_-_106447584 0.154 ENSMUST00000171678.1
ENSMUST00000048685.6
ENSMUST00000171925.1
Abhd14a


abhydrolase domain containing 14A


chr4_-_33189410 0.154 ENSMUST00000098181.2
Pm20d2
peptidase M20 domain containing 2
chr3_+_79884496 0.153 ENSMUST00000118853.1
Fam198b
family with sequence similarity 198, member B
chr1_+_143739551 0.152 ENSMUST00000050491.9
Glrx2
glutaredoxin 2 (thioltransferase)
chr19_+_26623419 0.151 ENSMUST00000176584.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr17_+_37046555 0.148 ENSMUST00000172789.1
Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr7_-_126625676 0.147 ENSMUST00000032961.3
Nupr1
nuclear protein transcription regulator 1
chr11_+_114890041 0.139 ENSMUST00000106582.2
ENSMUST00000045151.5
Cd300a

CD300A antigen

chrX_+_42151002 0.135 ENSMUST00000123245.1
Stag2
stromal antigen 2
chr8_-_3694167 0.132 ENSMUST00000005678.4
Fcer2a
Fc receptor, IgE, low affinity II, alpha polypeptide
chr12_+_116047713 0.130 ENSMUST00000073551.5
ENSMUST00000183125.1
Zfp386

zinc finger protein 386 (Kruppel-like)

chr8_-_85080679 0.126 ENSMUST00000093357.5
Wdr83
WD repeat domain containing 83
chr2_+_61593125 0.125 ENSMUST00000112494.1
Tank
TRAF family member-associated Nf-kappa B activator
chr1_+_171895664 0.125 ENSMUST00000097466.2
Gm10521
predicted gene 10521
chr15_+_58415456 0.124 ENSMUST00000037270.3
D15Ertd621e
DNA segment, Chr 15, ERATO Doi 621, expressed
chr3_-_103809278 0.123 ENSMUST00000063502.6
ENSMUST00000106832.1
ENSMUST00000106834.1
ENSMUST00000029435.8
Dclre1b



DNA cross-link repair 1B, PSO2 homolog (S. cerevisiae)



chr3_+_55140033 0.120 ENSMUST00000118963.2
ENSMUST00000061099.7
ENSMUST00000153009.1
Ccdc169


coiled-coil domain containing 169


chr3_-_101307079 0.116 ENSMUST00000097146.2
Gm10355
predicted gene 10355
chr15_+_89253035 0.109 ENSMUST00000088788.3
Ppp6r2
protein phosphatase 6, regulatory subunit 2
chr9_-_75441652 0.107 ENSMUST00000181896.1
A130057D12Rik
RIKEN cDNA A130057D12 gene
chr4_+_11579647 0.102 ENSMUST00000180239.1
Fsbp
fibrinogen silencer binding protein
chr9_-_54647199 0.098 ENSMUST00000128163.1
Acsbg1
acyl-CoA synthetase bubblegum family member 1
chrX_+_70385870 0.097 ENSMUST00000053981.5
1110012L19Rik
RIKEN cDNA 1110012L19 gene
chr7_-_19118357 0.094 ENSMUST00000141380.1
Gm4969
predicted gene 4969
chr11_-_115628260 0.092 ENSMUST00000178003.1
Slc25a19
solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19
chr17_+_45686322 0.085 ENSMUST00000024734.7
Mrpl14
mitochondrial ribosomal protein L14
chr14_+_73142490 0.085 ENSMUST00000170370.1
ENSMUST00000164822.1
ENSMUST00000165429.1
Rcbtb2


regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2


chr15_+_81872309 0.082 ENSMUST00000023116.6
Aco2
aconitase 2, mitochondrial
chr1_-_191907527 0.080 ENSMUST00000069573.5
1700034H15Rik
RIKEN cDNA 1700034H15 gene
chr7_+_28693997 0.076 ENSMUST00000108280.1
Fbxo27
F-box protein 27
chr11_-_4095344 0.073 ENSMUST00000004868.5
Mtfp1
mitochondrial fission process 1
chr7_-_126585775 0.071 ENSMUST00000084589.4
Cln3
ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)
chr11_+_68901538 0.066 ENSMUST00000073471.6
ENSMUST00000101014.2
ENSMUST00000128952.1
ENSMUST00000167436.1
Rpl26



ribosomal protein L26



chr6_-_97205549 0.064 ENSMUST00000164744.1
ENSMUST00000089287.5
Uba3

ubiquitin-like modifier activating enzyme 3

chr11_+_3649759 0.063 ENSMUST00000140242.1
Morc2a
microrchidia 2A
chr7_-_122021143 0.060 ENSMUST00000033160.8
Gga2
golgi associated, gamma adaptin ear containing, ARF binding protein 2
chr7_-_45211877 0.057 ENSMUST00000033057.7
Dkkl1
dickkopf-like 1
chr16_-_21995478 0.057 ENSMUST00000074230.4
ENSMUST00000060673.6
Liph

lipase, member H

chr2_-_91710519 0.057 ENSMUST00000028678.8
ENSMUST00000076803.5
Atg13

autophagy related 13

chr14_+_118787894 0.053 ENSMUST00000047761.6
ENSMUST00000071546.7
Cldn10

claudin 10

chr5_-_65335564 0.050 ENSMUST00000172780.1
Rfc1
replication factor C (activator 1) 1
chr11_+_98348404 0.048 ENSMUST00000078694.6
Ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr11_-_100527862 0.042 ENSMUST00000107385.1
Acly
ATP citrate lyase
chr2_+_91710900 0.040 ENSMUST00000142692.1
ENSMUST00000090608.5
Harbi1

harbinger transposase derived 1

chrX_-_143933089 0.040 ENSMUST00000087313.3
Dcx
doublecortin
chrX_-_38576166 0.039 ENSMUST00000050083.5
Cul4b
cullin 4B
chr11_+_94328242 0.036 ENSMUST00000021227.5
Ankrd40
ankyrin repeat domain 40
chr3_+_79884576 0.032 ENSMUST00000145992.1
Fam198b
family with sequence similarity 198, member B
chr14_-_60197173 0.032 ENSMUST00000131670.1
Atp8a2
ATPase, aminophospholipid transporter-like, class I, type 8A, member 2
chr15_-_10485385 0.028 ENSMUST00000168690.1
Brix1
BRX1, biogenesis of ribosomes, homolog (S. cerevisiae)
chr10_-_81291227 0.028 ENSMUST00000045744.6
Tjp3
tight junction protein 3
chr11_+_70030023 0.028 ENSMUST00000143920.2
Dlg4
discs, large homolog 4 (Drosophila)
chr6_-_124712131 0.026 ENSMUST00000004379.5
Emg1
EMG1 nucleolar protein homolog (S. cerevisiae)
chr14_-_54864055 0.025 ENSMUST00000142283.2
Homez
homeodomain leucine zipper-encoding gene
chr4_-_55532453 0.024 ENSMUST00000132746.1
ENSMUST00000107619.2
Klf4

Kruppel-like factor 4 (gut)

chr4_+_94739276 0.022 ENSMUST00000073939.6
ENSMUST00000102798.1
Tek

endothelial-specific receptor tyrosine kinase

chr7_+_13398115 0.021 ENSMUST00000005791.7
Cabp5
calcium binding protein 5
chr12_-_54695829 0.021 ENSMUST00000162106.1
ENSMUST00000160085.1
ENSMUST00000161592.1
ENSMUST00000163433.1
Eapp



E2F-associated phosphoprotein



chr9_+_77754526 0.020 ENSMUST00000034905.8
Gclc
glutamate-cysteine ligase, catalytic subunit
chr6_-_42520325 0.018 ENSMUST00000104977.2
Gm4877
predicted gene 4877
chr13_+_52596847 0.017 ENSMUST00000055087.6
Syk
spleen tyrosine kinase
chr15_+_10486008 0.014 ENSMUST00000022856.8
ENSMUST00000100775.3
ENSMUST00000169519.1
Rad1


RAD1 homolog (S. pombe)


chr3_-_153944425 0.011 ENSMUST00000150070.1
Acadm
acyl-Coenzyme A dehydrogenase, medium chain
chr17_-_45686214 0.006 ENSMUST00000113523.2
Tmem63b
transmembrane protein 63b
chr11_+_3650253 0.003 ENSMUST00000096441.3
Morc2a
microrchidia 2A
chr11_+_116198853 0.001 ENSMUST00000021130.6
Ten1
TEN1 telomerase capping complex subunit
chr6_-_30896735 0.000 ENSMUST00000048774.6
ENSMUST00000166192.1
ENSMUST00000135230.1
Copg2


coatomer protein complex, subunit gamma 2



Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.2 1.3 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.2 0.5 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.2 0.5 GO:0060084 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) synaptic transmission involved in micturition(GO:0060084)
0.2 1.6 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.1 1.1 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 0.3 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.1 0.1 GO:0007113 endomitotic cell cycle(GO:0007113)
0.1 0.2 GO:0033860 regulation of NAD(P)H oxidase activity(GO:0033860)
0.0 0.1 GO:0050859 regulation of activation of Janus kinase activity(GO:0010533) regulation of activation of JAK2 kinase activity(GO:0010534) negative regulation of serotonin secretion(GO:0014063) negative regulation of B cell receptor signaling pathway(GO:0050859) regulation of eosinophil activation(GO:1902566) negative regulation of membrane invagination(GO:1905154)
0.0 0.1 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0 0.1 GO:0031627 telomeric loop formation(GO:0031627)
0.0 0.6 GO:0060134 prepulse inhibition(GO:0060134)
0.0 0.8 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 2.6 GO:0007601 visual perception(GO:0007601)
0.0 0.5 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.1 GO:0014053 negative regulation of gamma-aminobutyric acid secretion(GO:0014053)
0.0 0.0 GO:1904995 negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.0 1.0 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.2 GO:0043206 extracellular fibril organization(GO:0043206)
0.0 0.3 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.0 0.3 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 0.3 GO:0048305 immunoglobulin secretion(GO:0048305)
0.0 0.2 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.0 0.1 GO:2000194 regulation of female gonad development(GO:2000194)
0.0 0.0 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.2 GO:0033572 transferrin transport(GO:0033572)
0.0 0.4 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.1 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.5 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.0 GO:0002741 positive regulation of cytokine secretion involved in immune response(GO:0002741)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 GO:0033391 chromatoid body(GO:0033391)
0.0 0.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 1.0 GO:0031201 SNARE complex(GO:0031201)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 1.3 GO:0035097 histone methyltransferase complex(GO:0035097)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.1 GO:0019841 retinol binding(GO:0019841)
0.3 1.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.2 0.5 GO:0004658 propionyl-CoA carboxylase activity(GO:0004658)
0.1 0.3 GO:0018121 imidazoleglycerol-phosphate synthase activity(GO:0000107) NAD(P)-cysteine ADP-ribosyltransferase activity(GO:0018071) NAD(P)-asparagine ADP-ribosyltransferase activity(GO:0018121) NAD(P)-serine ADP-ribosyltransferase activity(GO:0018127) 7-cyano-7-deazaguanine tRNA-ribosyltransferase activity(GO:0043867) purine deoxyribosyltransferase activity(GO:0044102)
0.1 1.3 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 1.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.5 GO:0042166 acetylcholine binding(GO:0042166)
0.0 0.1 GO:0019863 IgE binding(GO:0019863)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.0 GO:0031752 D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752)
0.0 1.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.6 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.5 GO:0070888 E-box binding(GO:0070888)
0.0 0.8 GO:0017022 myosin binding(GO:0017022)
0.0 1.4 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.2 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.5 GO:0043531 ADP binding(GO:0043531)