Motif ID: Zfp691

Z-value: 0.437


Transcription factors associated with Zfp691:

Gene SymbolEntrez IDGene Name
Zfp691 ENSMUSG00000045268.7 Zfp691

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp691mm10_v2_chr4_-_119174178_1191742210.039.1e-01Click!


Activity profile for motif Zfp691.

activity profile for motif Zfp691


Sorted Z-values histogram for motif Zfp691

Sorted Z-values for motif Zfp691



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp691

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_-_100786402 0.500 ENSMUST00000174038.1
ENSMUST00000091295.7
ENSMUST00000072119.8
Ccnb1


cyclin B1


chr7_+_28863831 0.491 ENSMUST00000138272.1
Lgals7
lectin, galactose binding, soluble 7
chr9_-_103761820 0.468 ENSMUST00000049452.8
Tmem108
transmembrane protein 108
chr8_+_88521344 0.464 ENSMUST00000034086.5
Nkd1
naked cuticle 1 homolog (Drosophila)
chr9_-_21067093 0.458 ENSMUST00000115494.2
Zglp1
zinc finger, GATA-like protein 1
chr3_-_33143227 0.458 ENSMUST00000108219.1
Pex5l
peroxisomal biogenesis factor 5-like
chr9_-_58202281 0.450 ENSMUST00000163897.1
Islr2
immunoglobulin superfamily containing leucine-rich repeat 2
chr9_-_108452377 0.413 ENSMUST00000035232.7
Klhdc8b
kelch domain containing 8B
chr8_+_72319033 0.395 ENSMUST00000067912.7
Klf2
Kruppel-like factor 2 (lung)
chr2_+_181715005 0.349 ENSMUST00000071585.3
ENSMUST00000148334.1
ENSMUST00000108763.1
Oprl1


opioid receptor-like 1


chr10_+_94576254 0.335 ENSMUST00000117929.1
Tmcc3
transmembrane and coiled coil domains 3
chr10_+_81183263 0.332 ENSMUST00000047665.6
Dapk3
death-associated protein kinase 3
chr9_-_106887000 0.305 ENSMUST00000055843.7
Rbm15b
RNA binding motif protein 15B
chr3_-_33143025 0.304 ENSMUST00000108226.1
Pex5l
peroxisomal biogenesis factor 5-like
chr10_-_112928974 0.279 ENSMUST00000099276.2
Atxn7l3b
ataxin 7-like 3B
chr6_-_24515036 0.279 ENSMUST00000052277.4
Iqub
IQ motif and ubiquitin domain containing
chr1_-_138856819 0.276 ENSMUST00000112025.1
2310009B15Rik
RIKEN cDNA 2310009B15 gene
chr12_+_86678685 0.262 ENSMUST00000021681.3
Vash1
vasohibin 1
chr2_-_155729359 0.262 ENSMUST00000040833.4
Edem2
ER degradation enhancer, mannosidase alpha-like 2
chr5_+_128601106 0.261 ENSMUST00000117102.2
Fzd10
frizzled homolog 10 (Drosophila)
chr3_-_92429403 0.260 ENSMUST00000047300.7
Gm9774
predicted pseudogene 9774
chr14_+_27238018 0.257 ENSMUST00000049206.5
Arhgef3
Rho guanine nucleotide exchange factor (GEF) 3
chr9_+_32696005 0.253 ENSMUST00000034534.6
ENSMUST00000050797.7
ENSMUST00000184887.1
Ets1


E26 avian leukemia oncogene 1, 5' domain


chr10_-_86732409 0.253 ENSMUST00000070435.4
Fabp3-ps1
fatty acid binding protein 3, muscle and heart, pseudogene 1
chr10_-_77166545 0.251 ENSMUST00000081654.6
Col18a1
collagen, type XVIII, alpha 1
chr8_-_77517898 0.225 ENSMUST00000076316.4
Arhgap10
Rho GTPase activating protein 10
chr14_-_70323783 0.214 ENSMUST00000151011.1
Slc39a14
solute carrier family 39 (zinc transporter), member 14
chr2_-_65529275 0.204 ENSMUST00000126837.1
Scn3a
sodium channel, voltage-gated, type III, alpha
chr10_+_81183000 0.193 ENSMUST00000178422.1
Dapk3
death-associated protein kinase 3
chr9_+_27299205 0.193 ENSMUST00000115247.1
ENSMUST00000133213.1
Igsf9b

immunoglobulin superfamily, member 9B

chr13_-_55528511 0.191 ENSMUST00000047877.4
Dok3
docking protein 3
chr6_+_134640940 0.189 ENSMUST00000062755.8
Loh12cr1
loss of heterozygosity, 12, chromosomal region 1 homolog (human)
chr7_-_45061706 0.188 ENSMUST00000107832.1
Prrg2
proline-rich Gla (G-carboxyglutamic acid) polypeptide 2
chr10_+_60003321 0.185 ENSMUST00000164083.2
Ascc1
activating signal cointegrator 1 complex subunit 1
chr4_-_129623870 0.184 ENSMUST00000106035.1
ENSMUST00000150357.1
ENSMUST00000030586.8
Ccdc28b


coiled coil domain containing 28B


chr6_+_28475101 0.183 ENSMUST00000168362.1
Snd1
staphylococcal nuclease and tudor domain containing 1
chr13_+_53525703 0.183 ENSMUST00000081132.4
Gm5449
predicted pseudogene 5449
chr14_-_20348040 0.178 ENSMUST00000022344.2
Ecd
ecdysoneless homolog (Drosophila)
chr4_+_126046903 0.164 ENSMUST00000030675.7
Mrps15
mitochondrial ribosomal protein S15
chr1_+_134193432 0.163 ENSMUST00000038445.6
Mybph
myosin binding protein H
chr15_+_44196135 0.157 ENSMUST00000038856.6
ENSMUST00000110289.3
Trhr

thyrotropin releasing hormone receptor

chr2_+_29802626 0.146 ENSMUST00000080065.2
Slc27a4
solute carrier family 27 (fatty acid transporter), member 4
chr3_+_98280427 0.146 ENSMUST00000090746.2
ENSMUST00000120541.1
Hmgcs2

3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2

chr15_-_83555681 0.137 ENSMUST00000061882.8
Mcat
malonyl CoA:ACP acyltransferase (mitochondrial)
chr13_-_54468805 0.134 ENSMUST00000026990.5
Thoc3
THO complex 3
chr7_+_143069249 0.129 ENSMUST00000060433.3
ENSMUST00000133410.2
ENSMUST00000105920.1
ENSMUST00000177841.1
ENSMUST00000147995.1
ENSMUST00000137856.1
Tssc4





tumor-suppressing subchromosomal transferable fragment 4





chr12_+_102129019 0.128 ENSMUST00000079020.4
Slc24a4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr3_-_67515487 0.119 ENSMUST00000178314.1
ENSMUST00000054825.4
Rarres1

retinoic acid receptor responder (tazarotene induced) 1

chr3_+_133338936 0.118 ENSMUST00000150386.1
ENSMUST00000125858.1
Ppa2

pyrophosphatase (inorganic) 2

chr7_-_45061651 0.116 ENSMUST00000007981.3
ENSMUST00000107831.1
Prrg2

proline-rich Gla (G-carboxyglutamic acid) polypeptide 2

chr5_-_32827109 0.113 ENSMUST00000144673.2
Gm20671
predicted gene 20671
chr5_+_75075464 0.110 ENSMUST00000160104.1
ENSMUST00000040477.3
Gsx2

GS homeobox 2

chr10_-_81183849 0.107 ENSMUST00000056086.4
4930442H23Rik
RIKEN cDNA 4930442H23 gene
chr9_+_50603892 0.103 ENSMUST00000044051.4
Timm8b
translocase of inner mitochondrial membrane 8B
chr16_+_90386382 0.100 ENSMUST00000065856.6
Hunk
hormonally upregulated Neu-associated kinase
chr16_+_32608920 0.094 ENSMUST00000023486.8
Tfrc
transferrin receptor
chr11_-_6626030 0.092 ENSMUST00000000394.7
ENSMUST00000136682.1
Tbrg4

transforming growth factor beta regulated gene 4

chr14_+_73142863 0.090 ENSMUST00000171767.1
ENSMUST00000163533.1
Rcbtb2

regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2

chr13_+_68582213 0.087 ENSMUST00000051784.8
Fastkd3
FAST kinase domains 3
chr4_+_129189760 0.086 ENSMUST00000106054.2
ENSMUST00000001365.2
Yars

tyrosyl-tRNA synthetase

chr2_+_24962400 0.082 ENSMUST00000028351.3
Dph7
diphthamine biosynethesis 7
chr7_-_105737376 0.080 ENSMUST00000098148.4
Rrp8
ribosomal RNA processing 8, methyltransferase, homolog (yeast)
chr3_-_62605140 0.079 ENSMUST00000058535.5
Gpr149
G protein-coupled receptor 149
chr11_-_120467414 0.079 ENSMUST00000076921.6
Arl16
ADP-ribosylation factor-like 16
chr15_-_76723814 0.074 ENSMUST00000036247.8
C030006K11Rik
RIKEN cDNA C030006K11 gene
chr19_+_11516473 0.073 ENSMUST00000163078.1
Ms4a6b
membrane-spanning 4-domains, subfamily A, member 6B
chr2_-_10130638 0.072 ENSMUST00000042290.7
Itih2
inter-alpha trypsin inhibitor, heavy chain 2
chr13_-_34130345 0.072 ENSMUST00000075774.3
Tubb2b
tubulin, beta 2B class IIB
chr11_+_120467635 0.071 ENSMUST00000140862.1
ENSMUST00000106205.1
ENSMUST00000106203.1
ENSMUST00000026900.7
Hgs



HGF-regulated tyrosine kinase substrate



chr8_-_22805596 0.070 ENSMUST00000163739.1
Ap3m2
adaptor-related protein complex 3, mu 2 subunit
chr11_+_58963790 0.063 ENSMUST00000075141.6
Trim17
tripartite motif-containing 17
chr13_+_55622999 0.059 ENSMUST00000021963.4
Caml
calcium modulating ligand
chr5_+_95956916 0.059 ENSMUST00000023840.5
Cxcl13
chemokine (C-X-C motif) ligand 13
chr8_-_124569696 0.057 ENSMUST00000063278.6
Agt
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr14_+_73142591 0.056 ENSMUST00000170368.1
Rcbtb2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr4_+_124714776 0.054 ENSMUST00000030734.4
Sf3a3
splicing factor 3a, subunit 3
chr6_-_34878006 0.054 ENSMUST00000115006.1
ENSMUST00000055097.4
ENSMUST00000115007.2
3110062M04Rik


RIKEN cDNA 3110062M04 gene


chr5_+_37050854 0.053 ENSMUST00000043794.4
Jakmip1
janus kinase and microtubule interacting protein 1
chr6_+_88465409 0.045 ENSMUST00000032165.9
Ruvbl1
RuvB-like protein 1
chrX_-_101268218 0.042 ENSMUST00000033664.7
Il2rg
interleukin 2 receptor, gamma chain
chr13_-_60897439 0.042 ENSMUST00000171347.1
ENSMUST00000021884.8
Ctla2b

cytotoxic T lymphocyte-associated protein 2 beta

chr13_-_68582087 0.037 ENSMUST00000045827.4
Mtrr
5-methyltetrahydrofolate-homocysteine methyltransferase reductase
chr2_+_119112793 0.034 ENSMUST00000140939.1
ENSMUST00000028795.3
Rad51

RAD51 homolog

chr2_+_26591423 0.032 ENSMUST00000152988.2
ENSMUST00000149789.1
Egfl7

EGF-like domain 7

chr6_+_70844499 0.030 ENSMUST00000034093.8
ENSMUST00000162950.1
Eif2ak3

eukaryotic translation initiation factor 2 alpha kinase 3

chr14_+_73143046 0.028 ENSMUST00000170677.1
ENSMUST00000167401.1
Rcbtb2

regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2

chr10_-_60002993 0.027 ENSMUST00000182116.1
Anapc16
anaphase promoting complex subunit 16
chr6_+_115544664 0.027 ENSMUST00000040234.7
Tsen2
tRNA splicing endonuclease 2 homolog (S. cerevisiae)
chr6_-_38837224 0.027 ENSMUST00000160962.1
Hipk2
homeodomain interacting protein kinase 2
chr9_+_50617516 0.024 ENSMUST00000141366.1
Pih1d2
PIH1 domain containing 2
chr14_+_73142490 0.024 ENSMUST00000170370.1
ENSMUST00000164822.1
ENSMUST00000165429.1
Rcbtb2


regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2


chr8_+_3621529 0.024 ENSMUST00000156380.2
Pet100
PET100 homolog (S. cerevisiae)
chr2_+_91265252 0.020 ENSMUST00000028691.6
Arfgap2
ADP-ribosylation factor GTPase activating protein 2
chr4_+_132535542 0.018 ENSMUST00000094657.3
ENSMUST00000105940.3
ENSMUST00000105939.3
ENSMUST00000150207.1
Dnajc8



DnaJ (Hsp40) homolog, subfamily C, member 8



chr9_-_50603792 0.017 ENSMUST00000000175.4
Sdhd
succinate dehydrogenase complex, subunit D, integral membrane protein
chr16_-_32165454 0.015 ENSMUST00000115163.3
ENSMUST00000144345.1
ENSMUST00000143682.1
ENSMUST00000115165.3
ENSMUST00000099991.4
ENSMUST00000130410.1
Nrros





negative regulator of reactive oxygen species





chr15_+_10177623 0.011 ENSMUST00000124470.1
Prlr
prolactin receptor
chr17_-_65772686 0.004 ENSMUST00000070673.7
Rab31
RAB31, member RAS oncogene family

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0031038 myosin II filament organization(GO:0031038) regulation of myosin II filament organization(GO:0043519)
0.1 0.5 GO:0043987 histone H3-S10 phosphorylation(GO:0043987)
0.1 0.3 GO:1904059 positive regulation of sensory perception of pain(GO:1904058) regulation of locomotor rhythm(GO:1904059)
0.1 0.8 GO:0051461 protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.1 0.7 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.1 0.3 GO:1904154 trimming of terminal mannose on B branch(GO:0036509) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.1 0.4 GO:0071499 response to laminar fluid shear stress(GO:0034616) cellular response to laminar fluid shear stress(GO:0071499)
0.1 0.3 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.1 0.3 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.1 0.1 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0 0.2 GO:0046684 response to pyrethroid(GO:0046684)
0.0 0.1 GO:0048162 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.0 0.1 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.1 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.1 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 0.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.2 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151)
0.0 0.1 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.0 0.3 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 0.2 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.0 GO:0032829 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829)
0.0 0.1 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.5 GO:0048599 oocyte development(GO:0048599)
0.0 0.5 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.0 GO:0010756 positive regulation of plasminogen activation(GO:0010756)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1 0.5 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.2 GO:0097255 R2TP complex(GO:0097255)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0097433 dense body(GO:0097433)
0.0 0.1 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.2 GO:0032982 myosin filament(GO:0032982)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.1 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.2 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 0.5 GO:0005113 patched binding(GO:0005113)
0.0 0.4 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.1 GO:0004998 transferrin receptor activity(GO:0004998)
0.0 0.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.2 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.1 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0031402 sodium ion binding(GO:0031402)
0.0 0.1 GO:0034943 acyl-CoA ligase activity(GO:0003996) 3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) very long-chain fatty acid-CoA ligase activity(GO:0031957) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)