Motif ID: Ets1

Z-value: 1.065


Transcription factors associated with Ets1:

Gene SymbolEntrez IDGene Name
Ets1 ENSMUSG00000032035.9 Ets1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ets1mm10_v2_chr9_+_32696005_32696121-0.301.6e-01Click!


Activity profile for motif Ets1.

activity profile for motif Ets1


Sorted Z-values histogram for motif Ets1

Sorted Z-values for motif Ets1



Network of associatons between targets according to the STRING database.



First level regulatory network of Ets1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_+_26229707 6.136 ENSMUST00000060716.5
ENSMUST00000164660.1
 Samd3

sterile alpha motif domain containing 3

chr4_-_63403330 4.947 ENSMUST00000035724.4
 Akna
AT-hook transcription factor
chr7_-_127218390 4.459 ENSMUST00000142356.1
ENSMUST00000106314.1
 Sept1

septin 1

chr7_-_127218303 4.396 ENSMUST00000106313.1
 Sept1
septin 1
chr11_-_20112876 3.735 ENSMUST00000000137.7
 Actr2
ARP2 actin-related protein 2
chr6_-_115994953 3.171 ENSMUST00000015511.8
 Plxnd1
plexin D1
chr11_-_76509419 2.953 ENSMUST00000094012.4
 Abr
active BCR-related gene
chr7_+_62348277 2.653 ENSMUST00000038775.4
 Ndn
necdin
chr11_+_96464587 2.581 ENSMUST00000103154.4
ENSMUST00000100521.3
ENSMUST00000100519.4
ENSMUST00000071510.7
ENSMUST00000107662.2
 Skap1




src family associated phosphoprotein 1




chr10_-_6980376 2.532 ENSMUST00000105617.1
 Ipcef1
interaction protein for cytohesin exchange factors 1
chr12_+_112760652 2.509 ENSMUST00000063888.3
 Pld4
phospholipase D family, member 4
chr17_+_29090969 2.507 ENSMUST00000119901.1
 Cdkn1a
cyclin-dependent kinase inhibitor 1A (P21)
chr18_+_50030977 2.483 ENSMUST00000145726.1
ENSMUST00000128377.1
 Tnfaip8

tumor necrosis factor, alpha-induced protein 8

chr11_-_105944412 2.472 ENSMUST00000019734.4
ENSMUST00000184269.1
ENSMUST00000150563.1
 Cyb561


cytochrome b-561


chr1_+_107511489 2.438 ENSMUST00000064916.2
 Serpinb2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr9_-_66514567 2.350 ENSMUST00000056890.8
 Fbxl22
F-box and leucine-rich repeat protein 22
chr1_+_107511416 2.292 ENSMUST00000009356.4
 Serpinb2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr3_-_89418287 2.274 ENSMUST00000029679.3
 Cks1b
CDC28 protein kinase 1b
chr3_-_33083016 2.179 ENSMUST00000078226.3
ENSMUST00000108224.1
 Pex5l

peroxisomal biogenesis factor 5-like

chr4_-_129573637 2.101 ENSMUST00000102596.1
 Lck
lymphocyte protein tyrosine kinase

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 420 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.5 10.0 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
0.0 6.8 GO:0000398 RNA splicing, via transesterification reactions(GO:0000375) RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.7 5.3 GO:0070474 positive regulation of uterine smooth muscle contraction(GO:0070474)
0.3 4.0 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
1.2 3.7 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
1.2 3.7 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 3.7 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.2 3.6 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.2 3.4 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.1 3.4 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.8 3.3 GO:0030576 Cajal body organization(GO:0030576)
0.5 3.2 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.3 3.2 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 3.2 GO:0043484 regulation of RNA splicing(GO:0043484)
0.6 3.0 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.2 3.0 GO:0061000 negative regulation of dendritic spine development(GO:0061000)
0.1 3.0 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.2 2.9 GO:0007413 axonal fasciculation(GO:0007413)
0.4 2.7 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 2.6 GO:0010763 positive regulation of fibroblast migration(GO:0010763)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 210 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 9.7 GO:0072687 meiotic spindle(GO:0072687)
0.2 5.8 GO:0000242 pericentriolar material(GO:0000242)
0.1 5.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 4.1 GO:0035371 microtubule plus-end(GO:0035371)
0.1 4.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 4.0 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.4 3.7 GO:0030478 actin cap(GO:0030478)
0.4 3.6 GO:0005818 aster(GO:0005818)
0.5 3.3 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.3 3.3 GO:0005687 U4 snRNP(GO:0005687)
0.1 3.3 GO:0002102 podosome(GO:0002102)
0.1 3.3 GO:0015030 Cajal body(GO:0015030)
0.5 3.2 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 3.2 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 3.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.3 2.9 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.3 2.9 GO:0030008 TRAPP complex(GO:0030008)
0.0 2.8 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 2.8 GO:0005681 spliceosomal complex(GO:0005681)
0.1 2.7 GO:0005680 anaphase-promoting complex(GO:0005680)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 257 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 9.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 7.6 GO:0005525 GTP binding(GO:0005525)
0.3 6.0 GO:0031681 G-protein beta-subunit binding(GO:0031681)
1.1 5.3 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 5.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 5.2 GO:0030695 GTPase regulator activity(GO:0030695)
0.1 4.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 4.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 4.4 GO:0019003 GDP binding(GO:0019003)
0.1 4.4 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 4.0 GO:0043015 gamma-tubulin binding(GO:0043015)
0.2 3.9 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 3.9 GO:0002039 p53 binding(GO:0002039)
0.0 3.8 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.1 3.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
1.1 3.3 GO:0070140 isopeptidase activity(GO:0070122) ubiquitin-like protein-specific isopeptidase activity(GO:0070138) SUMO-specific isopeptidase activity(GO:0070140)
0.7 3.3 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.4 3.2 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.4 3.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 3.0 GO:0004708 MAP kinase kinase activity(GO:0004708)