Motif ID: Hoxa11_Hoxc12
Z-value: 1.091
Transcription factors associated with Hoxa11_Hoxc12:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Hoxa11 | ENSMUSG00000038210.9 | Hoxa11 |
Hoxc12 | ENSMUSG00000050328.2 | Hoxc12 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.1 | 3.3 | GO:0009405 | pathogenesis(GO:0009405) |
0.8 | 2.3 | GO:0008228 | opsonization(GO:0008228) modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428) |
0.7 | 4.3 | GO:0042045 | epithelial fluid transport(GO:0042045) |
0.6 | 4.9 | GO:0070314 | G1 to G0 transition(GO:0070314) |
0.5 | 1.4 | GO:0072092 | ureteric bud invasion(GO:0072092) |
0.5 | 2.3 | GO:0042636 | negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279) |
0.4 | 12.3 | GO:0095500 | acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145) |
0.4 | 1.1 | GO:0050925 | negative regulation of negative chemotaxis(GO:0050925) |
0.4 | 1.1 | GO:0048352 | neural plate mediolateral regionalization(GO:0021998) mesoderm structural organization(GO:0048338) paraxial mesoderm structural organization(GO:0048352) |
0.3 | 3.3 | GO:0042118 | endothelial cell activation(GO:0042118) |
0.3 | 5.1 | GO:0021902 | commitment of neuronal cell to specific neuron type in forebrain(GO:0021902) |
0.3 | 1.3 | GO:0072362 | regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362) |
0.3 | 2.3 | GO:0038028 | insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) |
0.3 | 0.9 | GO:0003219 | atrioventricular node development(GO:0003162) cardiac right ventricle formation(GO:0003219) |
0.3 | 1.0 | GO:1990743 | protein sialylation(GO:1990743) |
0.2 | 2.4 | GO:0031999 | negative regulation of fatty acid beta-oxidation(GO:0031999) |
0.2 | 0.5 | GO:0070428 | granuloma formation(GO:0002432) negative regulation of toll-like receptor 3 signaling pathway(GO:0034140) toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) |
0.1 | 0.4 | GO:0044028 | DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029) |
0.1 | 0.9 | GO:0043983 | histone H4-K12 acetylation(GO:0043983) |
0.1 | 0.5 | GO:0051771 | negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771) |
0.1 | 0.9 | GO:1900029 | positive regulation of ruffle assembly(GO:1900029) |
0.1 | 0.7 | GO:0002317 | plasma cell differentiation(GO:0002317) |
0.1 | 0.3 | GO:0001732 | formation of cytoplasmic translation initiation complex(GO:0001732) |
0.1 | 0.4 | GO:0061511 | centriole elongation(GO:0061511) |
0.1 | 4.2 | GO:1900026 | positive regulation of substrate adhesion-dependent cell spreading(GO:1900026) |
0.1 | 2.1 | GO:0071398 | cellular response to fatty acid(GO:0071398) |
0.1 | 0.3 | GO:1901475 | pyruvate transmembrane transport(GO:1901475) |
0.1 | 0.2 | GO:0043201 | response to leucine(GO:0043201) cellular response to leucine(GO:0071233) |
0.1 | 0.8 | GO:0036120 | response to platelet-derived growth factor(GO:0036119) cellular response to platelet-derived growth factor stimulus(GO:0036120) |
0.1 | 0.6 | GO:0018026 | peptidyl-lysine monomethylation(GO:0018026) |
0.1 | 2.8 | GO:0001919 | regulation of receptor recycling(GO:0001919) |
0.1 | 1.0 | GO:0060218 | hematopoietic stem cell differentiation(GO:0060218) |
0.1 | 0.7 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
0.0 | 0.5 | GO:1901898 | negative regulation of relaxation of muscle(GO:1901078) regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898) |
0.0 | 0.2 | GO:0071787 | endoplasmic reticulum tubular network assembly(GO:0071787) |
0.0 | 0.2 | GO:0006842 | tricarboxylic acid transport(GO:0006842) succinate transport(GO:0015744) citrate transport(GO:0015746) |
0.0 | 0.2 | GO:0090527 | actin filament reorganization(GO:0090527) |
0.0 | 0.4 | GO:0019227 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
0.0 | 1.7 | GO:0030317 | sperm motility(GO:0030317) |
0.0 | 0.9 | GO:0048246 | macrophage chemotaxis(GO:0048246) |
0.0 | 0.2 | GO:0051189 | Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189) |
0.0 | 2.0 | GO:0032755 | positive regulation of interleukin-6 production(GO:0032755) |
0.0 | 0.1 | GO:0035526 | retrograde transport, plasma membrane to Golgi(GO:0035526) |
0.0 | 0.5 | GO:0021542 | dentate gyrus development(GO:0021542) |
0.0 | 0.2 | GO:0007000 | nucleolus organization(GO:0007000) |
0.0 | 0.2 | GO:0032926 | negative regulation of activin receptor signaling pathway(GO:0032926) |
0.0 | 0.2 | GO:0043030 | regulation of macrophage activation(GO:0043030) |
0.0 | 0.2 | GO:0019368 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
0.0 | 0.3 | GO:0046834 | lipid phosphorylation(GO:0046834) |
0.0 | 0.1 | GO:0051764 | actin crosslink formation(GO:0051764) |
0.0 | 0.3 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
0.0 | 2.1 | GO:0031032 | actomyosin structure organization(GO:0031032) |
0.0 | 1.2 | GO:0098792 | xenophagy(GO:0098792) |
0.0 | 0.2 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.4 | 4.3 | GO:0031088 | platelet dense granule membrane(GO:0031088) |
0.8 | 2.3 | GO:0043512 | inhibin A complex(GO:0043512) |
0.3 | 1.7 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
0.3 | 4.2 | GO:0042581 | specific granule(GO:0042581) |
0.3 | 2.8 | GO:0043083 | synaptic cleft(GO:0043083) |
0.2 | 0.9 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
0.1 | 0.4 | GO:0005943 | phosphatidylinositol 3-kinase complex, class IA(GO:0005943) |
0.1 | 0.5 | GO:0031084 | BLOC-2 complex(GO:0031084) |
0.1 | 1.0 | GO:0000138 | Golgi trans cisterna(GO:0000138) |
0.1 | 1.3 | GO:0016580 | Sin3 complex(GO:0016580) |
0.1 | 5.1 | GO:0000118 | histone deacetylase complex(GO:0000118) |
0.0 | 0.2 | GO:0043564 | Ku70:Ku80 complex(GO:0043564) |
0.0 | 0.3 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
0.0 | 1.1 | GO:0030673 | axolemma(GO:0030673) |
0.0 | 0.5 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
0.0 | 0.2 | GO:0070545 | PeBoW complex(GO:0070545) |
0.0 | 0.4 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
0.0 | 0.2 | GO:0030122 | AP-2 adaptor complex(GO:0030122) |
0.0 | 0.4 | GO:0034451 | centriolar satellite(GO:0034451) |
0.0 | 0.2 | GO:0031229 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) |
0.0 | 0.5 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
0.0 | 1.0 | GO:0032587 | ruffle membrane(GO:0032587) |
0.0 | 1.1 | GO:0005901 | caveola(GO:0005901) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
4.1 | 12.3 | GO:0030549 | acetylcholine receptor activator activity(GO:0030549) |
1.4 | 4.3 | GO:0005220 | inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220) |
0.8 | 3.3 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
0.5 | 2.3 | GO:0001849 | complement component C1q binding(GO:0001849) |
0.4 | 2.8 | GO:0004971 | AMPA glutamate receptor activity(GO:0004971) |
0.4 | 2.3 | GO:0070699 | type II activin receptor binding(GO:0070699) |
0.4 | 3.3 | GO:0015643 | toxic substance binding(GO:0015643) |
0.2 | 1.0 | GO:0003835 | beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835) |
0.2 | 1.7 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
0.2 | 1.1 | GO:0098821 | BMP receptor activity(GO:0098821) |
0.2 | 1.3 | GO:0035033 | histone deacetylase regulator activity(GO:0035033) |
0.1 | 1.1 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
0.1 | 2.3 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
0.1 | 0.6 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
0.1 | 1.4 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
0.1 | 4.2 | GO:0045296 | cadherin binding(GO:0045296) |
0.1 | 0.4 | GO:0004165 | dodecenoyl-CoA delta-isomerase activity(GO:0004165) |
0.1 | 0.3 | GO:0050833 | pyruvate transmembrane transporter activity(GO:0050833) |
0.1 | 0.5 | GO:0004661 | protein geranylgeranyltransferase activity(GO:0004661) |
0.1 | 0.9 | GO:0042608 | T cell receptor binding(GO:0042608) |
0.1 | 2.1 | GO:0005504 | fatty acid binding(GO:0005504) |
0.1 | 0.4 | GO:0046934 | phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) |
0.1 | 0.2 | GO:0017153 | sodium:dicarboxylate symporter activity(GO:0017153) |
0.0 | 0.3 | GO:0001727 | lipid kinase activity(GO:0001727) |
0.0 | 0.2 | GO:0070728 | leucine binding(GO:0070728) |
0.0 | 0.1 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
0.0 | 0.9 | GO:0005112 | Notch binding(GO:0005112) |
0.0 | 0.2 | GO:0051575 | 5'-deoxyribose-5-phosphate lyase activity(GO:0051575) |
0.0 | 0.8 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
0.0 | 0.5 | GO:0004679 | AMP-activated protein kinase activity(GO:0004679) |
0.0 | 1.9 | GO:0043851 | rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA (uridine-2'-O-)-methyltransferase activity(GO:0008650) rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383) selenocysteine methyltransferase activity(GO:0016205) rRNA (adenine) methyltransferase activity(GO:0016433) rRNA (cytosine) methyltransferase activity(GO:0016434) rRNA (guanine) methyltransferase activity(GO:0016435) 1-phenanthrol methyltransferase activity(GO:0018707) protein-arginine N5-methyltransferase activity(GO:0019702) dimethylarsinite methyltransferase activity(GO:0034541) 4,5-dihydroxybenzo(a)pyrene methyltransferase activity(GO:0034807) 1-hydroxypyrene methyltransferase activity(GO:0034931) 1-hydroxy-6-methoxypyrene methyltransferase activity(GO:0034933) demethylmenaquinone methyltransferase activity(GO:0043770) cobalt-precorrin-6B C5-methyltransferase activity(GO:0043776) cobalt-precorrin-7 C15-methyltransferase activity(GO:0043777) cobalt-precorrin-5B C1-methyltransferase activity(GO:0043780) cobalt-precorrin-3 C17-methyltransferase activity(GO:0043782) dimethylamine methyltransferase activity(GO:0043791) hydroxyneurosporene-O-methyltransferase activity(GO:0043803) tRNA (adenine-57, 58-N(1)-) methyltransferase activity(GO:0043827) methylamine-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043833) trimethylamine methyltransferase activity(GO:0043834) methanol-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043851) monomethylamine methyltransferase activity(GO:0043852) P-methyltransferase activity(GO:0051994) Se-methyltransferase activity(GO:0051995) 2-phytyl-1,4-naphthoquinone methyltransferase activity(GO:0052624) tRNA (uracil-2'-O-)-methyltransferase activity(GO:0052665) tRNA (cytosine-2'-O-)-methyltransferase activity(GO:0052666) phosphomethylethanolamine N-methyltransferase activity(GO:0052667) tRNA (cytosine-3-)-methyltransferase activity(GO:0052735) rRNA (cytosine-2'-O-)-methyltransferase activity(GO:0070677) rRNA (cytosine-N4-)-methyltransferase activity(GO:0071424) trihydroxyferuloyl spermidine O-methyltransferase activity(GO:0080012) |
0.0 | 0.5 | GO:0070530 | K63-linked polyubiquitin binding(GO:0070530) |
0.0 | 0.3 | GO:0030169 | low-density lipoprotein particle binding(GO:0030169) |
0.0 | 0.6 | GO:0008009 | chemokine activity(GO:0008009) |
0.0 | 0.7 | GO:0046875 | ephrin receptor binding(GO:0046875) |
0.0 | 0.2 | GO:0102338 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
0.0 | 0.3 | GO:0004697 | protein kinase C activity(GO:0004697) |
0.0 | 0.9 | GO:0004402 | histone acetyltransferase activity(GO:0004402) |
0.0 | 0.5 | GO:0004120 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715) |
0.0 | 0.7 | GO:0008276 | protein methyltransferase activity(GO:0008276) |