Motif ID: Glis2
Z-value: 1.206
Transcription factors associated with Glis2:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Glis2 | ENSMUSG00000014303.7 | Glis2 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Glis2 | mm10_v2_chr16_+_4594683_4594735 | -0.31 | 1.5e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.9 | 13.3 | GO:2001199 | negative regulation of dendritic cell differentiation(GO:2001199) |
1.3 | 5.3 | GO:0051866 | general adaptation syndrome(GO:0051866) |
0.9 | 12.2 | GO:0048672 | positive regulation of collateral sprouting(GO:0048672) |
0.9 | 2.8 | GO:2000501 | natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501) |
0.9 | 2.7 | GO:0021577 | hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589) |
0.9 | 4.4 | GO:0015671 | oxygen transport(GO:0015671) |
0.8 | 2.4 | GO:0010752 | negative regulation of antigen processing and presentation(GO:0002578) negative regulation of nitric oxide mediated signal transduction(GO:0010751) regulation of cGMP-mediated signaling(GO:0010752) negative regulation of plasminogen activation(GO:0010757) |
0.8 | 2.3 | GO:0072070 | establishment or maintenance of polarity of embryonic epithelium(GO:0016332) loop of Henle development(GO:0072070) metanephric loop of Henle development(GO:0072236) |
0.6 | 1.8 | GO:0010899 | regulation of phosphatidylcholine catabolic process(GO:0010899) |
0.6 | 3.6 | GO:0032796 | uropod organization(GO:0032796) |
0.6 | 1.7 | GO:0045085 | negative regulation of interleukin-2 biosynthetic process(GO:0045085) |
0.5 | 2.1 | GO:1904565 | response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566) |
0.5 | 2.5 | GO:0040032 | post-embryonic body morphogenesis(GO:0040032) |
0.4 | 2.1 | GO:0070345 | negative regulation of fat cell proliferation(GO:0070345) |
0.4 | 1.5 | GO:0046898 | response to cycloheximide(GO:0046898) |
0.4 | 1.8 | GO:0035984 | response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984) |
0.4 | 4.0 | GO:0007220 | Notch receptor processing(GO:0007220) |
0.3 | 0.9 | GO:1902219 | regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902218) negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219) |
0.3 | 4.0 | GO:0021684 | cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) |
0.3 | 2.8 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
0.3 | 6.6 | GO:0008340 | determination of adult lifespan(GO:0008340) |
0.3 | 2.7 | GO:0045040 | protein import into mitochondrial outer membrane(GO:0045040) negative regulation of protein folding(GO:1903333) |
0.2 | 2.0 | GO:0018230 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
0.2 | 1.5 | GO:0001842 | neural fold formation(GO:0001842) |
0.2 | 1.7 | GO:0015074 | DNA integration(GO:0015074) |
0.2 | 0.8 | GO:0035606 | peptidyl-cysteine S-trans-nitrosylation(GO:0035606) |
0.2 | 1.7 | GO:0048742 | regulation of skeletal muscle fiber development(GO:0048742) |
0.2 | 0.8 | GO:0075525 | viral translational termination-reinitiation(GO:0075525) |
0.2 | 0.8 | GO:0014886 | transition between slow and fast fiber(GO:0014886) |
0.2 | 1.1 | GO:0016584 | nucleosome positioning(GO:0016584) |
0.2 | 0.6 | GO:0072369 | regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369) |
0.1 | 5.8 | GO:0034260 | negative regulation of GTPase activity(GO:0034260) |
0.1 | 0.7 | GO:0070966 | nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) |
0.1 | 0.7 | GO:0090038 | negative regulation of protein kinase C signaling(GO:0090038) |
0.1 | 1.7 | GO:0042711 | maternal behavior(GO:0042711) |
0.1 | 0.9 | GO:0001771 | immunological synapse formation(GO:0001771) |
0.1 | 1.2 | GO:0001675 | acrosome assembly(GO:0001675) |
0.1 | 0.7 | GO:0009249 | protein lipoylation(GO:0009249) |
0.1 | 0.3 | GO:0060217 | hemangioblast cell differentiation(GO:0060217) |
0.1 | 1.0 | GO:0046485 | ether lipid metabolic process(GO:0046485) |
0.1 | 0.3 | GO:0070844 | misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846) |
0.1 | 1.8 | GO:0046855 | phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) |
0.1 | 0.8 | GO:0031053 | primary miRNA processing(GO:0031053) |
0.1 | 2.3 | GO:0033006 | regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304) |
0.1 | 0.8 | GO:0007512 | adult heart development(GO:0007512) |
0.1 | 0.3 | GO:0001978 | regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) |
0.1 | 1.6 | GO:0016188 | synaptic vesicle maturation(GO:0016188) |
0.1 | 0.6 | GO:0033198 | response to ATP(GO:0033198) |
0.1 | 0.3 | GO:0018065 | protein-cofactor linkage(GO:0018065) |
0.1 | 3.6 | GO:0048013 | ephrin receptor signaling pathway(GO:0048013) |
0.1 | 0.7 | GO:0036158 | outer dynein arm assembly(GO:0036158) |
0.1 | 0.2 | GO:0044778 | meiotic DNA integrity checkpoint(GO:0044778) |
0.1 | 2.0 | GO:0071542 | dopaminergic neuron differentiation(GO:0071542) |
0.1 | 0.5 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
0.1 | 0.4 | GO:0006621 | protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437) |
0.1 | 0.5 | GO:0033601 | positive regulation of mammary gland epithelial cell proliferation(GO:0033601) |
0.1 | 0.3 | GO:0046533 | eye photoreceptor cell fate commitment(GO:0042706) negative regulation of photoreceptor cell differentiation(GO:0046533) photoreceptor cell fate commitment(GO:0046552) retinal rod cell differentiation(GO:0060221) |
0.1 | 1.7 | GO:0010955 | negative regulation of protein processing(GO:0010955) negative regulation of protein maturation(GO:1903318) |
0.1 | 0.3 | GO:0021914 | negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914) |
0.1 | 0.6 | GO:0015697 | quaternary ammonium group transport(GO:0015697) |
0.1 | 1.4 | GO:0048025 | negative regulation of mRNA splicing, via spliceosome(GO:0048025) |
0.0 | 1.0 | GO:0042297 | vocal learning(GO:0042297) imitative learning(GO:0098596) learned vocalization behavior or vocal learning(GO:0098598) |
0.0 | 0.3 | GO:2000628 | regulation of miRNA metabolic process(GO:2000628) |
0.0 | 0.4 | GO:0035729 | response to hepatocyte growth factor(GO:0035728) cellular response to hepatocyte growth factor stimulus(GO:0035729) |
0.0 | 1.2 | GO:0043984 | histone H4-K16 acetylation(GO:0043984) |
0.0 | 0.5 | GO:0030836 | positive regulation of actin filament depolymerization(GO:0030836) |
0.0 | 1.1 | GO:0010107 | potassium ion import(GO:0010107) |
0.0 | 0.4 | GO:0006012 | galactose metabolic process(GO:0006012) |
0.0 | 2.1 | GO:0042073 | intraciliary transport(GO:0042073) |
0.0 | 0.4 | GO:0090435 | protein localization to nuclear envelope(GO:0090435) |
0.0 | 0.5 | GO:0043303 | mast cell activation involved in immune response(GO:0002279) mast cell degranulation(GO:0043303) |
0.0 | 0.3 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
0.0 | 1.5 | GO:0045668 | negative regulation of osteoblast differentiation(GO:0045668) |
0.0 | 1.5 | GO:0035058 | nonmotile primary cilium assembly(GO:0035058) |
0.0 | 0.5 | GO:0071539 | protein localization to centrosome(GO:0071539) |
0.0 | 0.5 | GO:0042921 | glucocorticoid receptor signaling pathway(GO:0042921) |
0.0 | 0.9 | GO:0045747 | positive regulation of Notch signaling pathway(GO:0045747) |
0.0 | 0.2 | GO:2000601 | positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601) |
0.0 | 0.1 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
0.0 | 0.2 | GO:0006744 | ubiquinone biosynthetic process(GO:0006744) |
0.0 | 0.1 | GO:0060484 | lung-associated mesenchyme development(GO:0060484) |
0.0 | 0.3 | GO:2000398 | regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398) |
0.0 | 0.6 | GO:0006506 | GPI anchor biosynthetic process(GO:0006506) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 2.4 | GO:0005577 | fibrinogen complex(GO:0005577) |
0.8 | 2.3 | GO:0044194 | cytolytic granule(GO:0044194) |
0.5 | 4.4 | GO:0005833 | hemoglobin complex(GO:0005833) |
0.4 | 2.9 | GO:0090571 | RNA polymerase II transcription repressor complex(GO:0090571) |
0.4 | 5.8 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
0.4 | 0.4 | GO:0097418 | neurofibrillary tangle(GO:0097418) |
0.4 | 1.5 | GO:0090537 | CERF complex(GO:0090537) |
0.2 | 2.4 | GO:0002178 | palmitoyltransferase complex(GO:0002178) |
0.2 | 1.0 | GO:0072487 | MSL complex(GO:0072487) |
0.2 | 2.8 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
0.2 | 1.5 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
0.2 | 0.5 | GO:0043209 | myelin sheath(GO:0043209) |
0.1 | 3.6 | GO:0001891 | phagocytic cup(GO:0001891) |
0.1 | 0.8 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
0.1 | 0.8 | GO:0097452 | GAIT complex(GO:0097452) |
0.1 | 1.8 | GO:0034362 | low-density lipoprotein particle(GO:0034362) |
0.1 | 0.3 | GO:0033193 | Lsd1/2 complex(GO:0033193) |
0.1 | 0.7 | GO:0036157 | outer dynein arm(GO:0036157) |
0.1 | 5.4 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
0.1 | 0.5 | GO:0035189 | Rb-E2F complex(GO:0035189) |
0.1 | 1.0 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
0.1 | 0.8 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
0.1 | 0.9 | GO:0034709 | methylosome(GO:0034709) |
0.1 | 2.7 | GO:0016235 | aggresome(GO:0016235) |
0.1 | 1.2 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
0.1 | 0.8 | GO:0071598 | neuronal ribonucleoprotein granule(GO:0071598) |
0.1 | 1.1 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
0.1 | 2.1 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
0.1 | 0.8 | GO:0005675 | holo TFIIH complex(GO:0005675) |
0.1 | 1.5 | GO:0034451 | centriolar satellite(GO:0034451) |
0.0 | 0.2 | GO:0030896 | checkpoint clamp complex(GO:0030896) |
0.0 | 0.4 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
0.0 | 0.5 | GO:0005869 | dynactin complex(GO:0005869) |
0.0 | 2.1 | GO:0005882 | intermediate filament(GO:0005882) |
0.0 | 4.6 | GO:0014069 | postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572) |
0.0 | 0.3 | GO:0097470 | ribbon synapse(GO:0097470) |
0.0 | 2.7 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.0 | 2.3 | GO:0009986 | cell surface(GO:0009986) |
0.0 | 2.1 | GO:0043198 | dendritic shaft(GO:0043198) |
0.0 | 0.2 | GO:0031209 | SCAR complex(GO:0031209) |
0.0 | 4.1 | GO:0005769 | early endosome(GO:0005769) |
0.0 | 1.2 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
0.0 | 1.0 | GO:0042734 | presynaptic membrane(GO:0042734) |
0.0 | 0.2 | GO:0035631 | CD40 receptor complex(GO:0035631) |
0.0 | 0.7 | GO:0030964 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
0.0 | 0.0 | GO:0061689 | tricellular tight junction(GO:0061689) |
0.0 | 0.7 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
0.0 | 1.8 | GO:0009897 | external side of plasma membrane(GO:0009897) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.9 | 11.6 | GO:0019841 | retinol binding(GO:0019841) |
1.1 | 4.4 | GO:0031721 | hemoglobin alpha binding(GO:0031721) |
0.9 | 2.7 | GO:0010698 | acetyltransferase activator activity(GO:0010698) |
0.8 | 2.4 | GO:0070052 | collagen V binding(GO:0070052) |
0.6 | 2.3 | GO:1902379 | chemoattractant activity involved in axon guidance(GO:1902379) |
0.6 | 1.7 | GO:0042289 | MHC class II protein binding(GO:0042289) |
0.5 | 1.8 | GO:0035851 | histone deacetylase activity (H4-K16 specific)(GO:0034739) Krueppel-associated box domain binding(GO:0035851) |
0.5 | 2.8 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
0.4 | 2.5 | GO:0051429 | corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430) |
0.4 | 2.0 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
0.4 | 1.8 | GO:0030229 | very-low-density lipoprotein particle receptor activity(GO:0030229) |
0.4 | 3.6 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
0.4 | 2.1 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915) |
0.3 | 0.9 | GO:0005128 | erythropoietin receptor binding(GO:0005128) |
0.3 | 0.8 | GO:0035605 | peptidyl-cysteine S-nitrosylase activity(GO:0035605) |
0.2 | 2.1 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
0.2 | 1.1 | GO:0001226 | RNA polymerase II transcription corepressor binding(GO:0001226) |
0.2 | 5.7 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
0.2 | 0.6 | GO:0035381 | purinergic nucleotide receptor activity(GO:0001614) extracellular ATP-gated cation channel activity(GO:0004931) nucleotide receptor activity(GO:0016502) ATP-gated ion channel activity(GO:0035381) purinergic receptor activity(GO:0035586) |
0.2 | 5.0 | GO:0005112 | Notch binding(GO:0005112) |
0.2 | 1.5 | GO:0051434 | BH3 domain binding(GO:0051434) |
0.2 | 0.8 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
0.1 | 1.2 | GO:0031811 | G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812) |
0.1 | 0.4 | GO:0046923 | ER retention sequence binding(GO:0046923) |
0.1 | 0.5 | GO:0004839 | ubiquitin activating enzyme activity(GO:0004839) |
0.1 | 0.3 | GO:0042903 | tubulin deacetylase activity(GO:0042903) |
0.1 | 0.6 | GO:1990829 | C-rich single-stranded DNA binding(GO:1990829) |
0.1 | 2.3 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
0.1 | 2.8 | GO:0008009 | chemokine activity(GO:0008009) |
0.1 | 1.8 | GO:0017161 | phosphohistidine phosphatase activity(GO:0008969) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) NADP phosphatase activity(GO:0019178) 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity(GO:0043726) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052867) IDP phosphatase activity(GO:1990003) |
0.1 | 0.6 | GO:0015651 | quaternary ammonium group transmembrane transporter activity(GO:0015651) |
0.1 | 3.3 | GO:0042169 | SH2 domain binding(GO:0042169) |
0.1 | 3.6 | GO:0046875 | ephrin receptor binding(GO:0046875) |
0.1 | 1.2 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
0.1 | 3.0 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
0.1 | 1.0 | GO:0050253 | prenylcysteine methylesterase activity(GO:0010296) 1-oxa-2-oxocycloheptane lactonase activity(GO:0018731) sulfolactone hydrolase activity(GO:0018732) butyrolactone hydrolase activity(GO:0018734) endosulfan lactone lactonase activity(GO:0034892) L-ascorbate 6-phosphate lactonase activity(GO:0035460) Ser-tRNA(Thr) hydrolase activity(GO:0043905) Ala-tRNA(Pro) hydrolase activity(GO:0043906) Cys-tRNA(Pro) hydrolase activity(GO:0043907) Ser(Gly)-tRNA(Ala) hydrolase activity(GO:0043908) all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity(GO:0047376) retinyl-palmitate esterase activity(GO:0050253) mannosyl-oligosaccharide 1,6-alpha-mannosidase activity(GO:0052767) mannosyl-oligosaccharide 1,3-alpha-mannosidase activity(GO:0052768) methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032) |
0.0 | 0.4 | GO:0035615 | clathrin heavy chain binding(GO:0032050) clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
0.0 | 0.5 | GO:0035014 | phosphatidylinositol 3-kinase regulator activity(GO:0035014) |
0.0 | 1.0 | GO:0042165 | neurotransmitter binding(GO:0042165) |
0.0 | 2.2 | GO:0035496 | UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980) O antigen polymerase activity(GO:0008755) lipopolysaccharide-1,6-galactosyltransferase activity(GO:0008921) cellulose synthase activity(GO:0016759) 9-phenanthrol UDP-glucuronosyltransferase activity(GO:0018715) 1-phenanthrol glycosyltransferase activity(GO:0018716) 9-phenanthrol glycosyltransferase activity(GO:0018717) 1,2-dihydroxy-phenanthrene glycosyltransferase activity(GO:0018718) phenanthrol glycosyltransferase activity(GO:0019112) alpha-1,2-galactosyltransferase activity(GO:0031278) dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0033556) endogalactosaminidase activity(GO:0033931) lipopolysaccharide-1,5-galactosyltransferase activity(GO:0035496) dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0042283) inositol phosphoceramide synthase activity(GO:0045140) alpha-(1->3)-fucosyltransferase activity(GO:0046920) indole-3-butyrate beta-glucosyltransferase activity(GO:0052638) salicylic acid glucosyltransferase (ester-forming) activity(GO:0052639) salicylic acid glucosyltransferase (glucoside-forming) activity(GO:0052640) benzoic acid glucosyltransferase activity(GO:0052641) chondroitin hydrolase activity(GO:0052757) dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity(GO:0052824) cytokinin 9-beta-glucosyltransferase activity(GO:0080062) |
0.0 | 0.9 | GO:0008327 | methyl-CpG binding(GO:0008327) |
0.0 | 0.4 | GO:0031996 | thioesterase binding(GO:0031996) |
0.0 | 0.4 | GO:0070402 | NADPH binding(GO:0070402) |
0.0 | 0.4 | GO:0016857 | racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857) |
0.0 | 6.1 | GO:0005096 | GTPase activator activity(GO:0005096) |
0.0 | 1.1 | GO:0020037 | heme binding(GO:0020037) |
0.0 | 0.8 | GO:0031369 | translation initiation factor binding(GO:0031369) |
0.0 | 0.8 | GO:0051019 | mitogen-activated protein kinase binding(GO:0051019) |
0.0 | 0.4 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
0.0 | 0.4 | GO:0005487 | nucleocytoplasmic transporter activity(GO:0005487) |
0.0 | 1.2 | GO:0031490 | chromatin DNA binding(GO:0031490) |