Motif ID: Hmx2

Z-value: 0.473


Transcription factors associated with Hmx2:

Gene SymbolEntrez IDGene Name
Hmx2 ENSMUSG00000050100.7 Hmx2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hmx2mm10_v2_chr7_+_131548755_131548773-0.087.3e-01Click!


Activity profile for motif Hmx2.

activity profile for motif Hmx2


Sorted Z-values histogram for motif Hmx2

Sorted Z-values for motif Hmx2



Network of associatons between targets according to the STRING database.



First level regulatory network of Hmx2

PNG image of the network

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Top targets:


Showing 1 to 20 of 128 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_-_37552904 0.860 ENSMUST00000065668.5
 Nrgn
neurogranin
chr5_-_28210022 0.808 ENSMUST00000118882.1
 Cnpy1
canopy 1 homolog (zebrafish)
chr5_+_23850590 0.764 ENSMUST00000181574.1
 2700038G22Rik
RIKEN cDNA 2700038G22 gene
chr18_-_34579072 0.631 ENSMUST00000079287.5
 Nme5
NME/NM23 family member 5
chr3_+_109573907 0.574 ENSMUST00000106576.2
 Vav3
vav 3 oncogene
chr3_+_84952146 0.521 ENSMUST00000029727.7
 Fbxw7
F-box and WD-40 domain protein 7
chr18_+_50051702 0.520 ENSMUST00000134348.1
ENSMUST00000153873.2
 Tnfaip8

tumor necrosis factor, alpha-induced protein 8

chr12_-_98901478 0.503 ENSMUST00000065716.6
 Eml5
echinoderm microtubule associated protein like 5
chr6_-_137169678 0.472 ENSMUST00000119610.1
 Rerg
RAS-like, estrogen-regulated, growth-inhibitor
chr4_+_145510759 0.468 ENSMUST00000105742.1
ENSMUST00000136309.1
 Gm13225

predicted gene 13225

chr15_-_42676967 0.463 ENSMUST00000022921.5
 Angpt1
angiopoietin 1
chr10_+_128908907 0.449 ENSMUST00000105229.1
 Cd63
CD63 antigen
chr12_-_90969768 0.446 ENSMUST00000181184.1
 4930544I03Rik
RIKEN cDNA 4930544I03 gene
chr4_+_147492417 0.418 ENSMUST00000105721.2
 Gm13152
predicted gene 13152
chr14_-_48667508 0.417 ENSMUST00000144465.1
ENSMUST00000133479.1
ENSMUST00000119070.1
ENSMUST00000152018.1
 Otx2



orthodenticle homolog 2 (Drosophila)



chr2_+_35132194 0.375 ENSMUST00000113034.1
ENSMUST00000113037.3
ENSMUST00000113033.2
 Cep110


centrosomal protein 110


chr11_-_100822525 0.374 ENSMUST00000107358.2
 Stat5b
signal transducer and activator of transcription 5B
chr5_-_28210168 0.359 ENSMUST00000117098.1
 Cnpy1
canopy 1 homolog (zebrafish)
chr5_-_20951769 0.356 ENSMUST00000036489.5
 Rsbn1l
round spermatid basic protein 1-like
chr3_-_116712644 0.354 ENSMUST00000029569.2
 Slc35a3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 35 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.9 GO:1900273 positive regulation of long-term synaptic potentiation(GO:1900273)
0.1 0.6 GO:0046036 GTP biosynthetic process(GO:0006183) CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036)
0.2 0.5 GO:0030210 heparin biosynthetic process(GO:0030210)
0.1 0.5 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.0 0.5 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 0.5 GO:0032611 interleukin-1 beta production(GO:0032611)
0.1 0.4 GO:0046544 regulation of natural killer cell proliferation(GO:0032817) positive regulation of natural killer cell proliferation(GO:0032819) development of secondary male sexual characteristics(GO:0046544)
0.1 0.4 GO:0045472 response to ether(GO:0045472)
0.1 0.4 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.1 0.4 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.1 0.4 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.1 0.3 GO:0035633 maintenance of blood-brain barrier(GO:0035633)
0.1 0.3 GO:0070269 pyroptosis(GO:0070269)
0.1 0.3 GO:0032512 regulation of protein phosphatase type 2B activity(GO:0032512) positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0 0.3 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.3 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.3 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 0.2 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.2 GO:0051694 pointed-end actin filament capping(GO:0051694)

Gene overrepresentation in cellular_component category:

Showing 1 to 15 of 15 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.9 GO:0044327 dendritic spine head(GO:0044327)
0.1 0.7 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.5 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 0.4 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.1 0.3 GO:0061702 inflammasome complex(GO:0061702)
0.0 0.3 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 0.2 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.2 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.2 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.1 GO:0071438 NADPH oxidase complex(GO:0043020) invadopodium membrane(GO:0071438)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.9 GO:0070300 phosphatidic acid binding(GO:0070300)
0.1 0.7 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.6 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 0.5 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.5 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.4 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.3 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.3 GO:0043495 protein anchor(GO:0043495)
0.0 0.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.2 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.2 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.1 GO:0070330 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392) aromatase activity(GO:0070330)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0042609 CD4 receptor binding(GO:0042609)