Motif ID: Zkscan1

Z-value: 0.432


Transcription factors associated with Zkscan1:

Gene SymbolEntrez IDGene Name
Zkscan1 ENSMUSG00000029729.6 Zkscan1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zkscan1mm10_v2_chr5_+_138085083_1380851470.038.9e-01Click!


Activity profile for motif Zkscan1.

activity profile for motif Zkscan1


Sorted Z-values histogram for motif Zkscan1

Sorted Z-values for motif Zkscan1



Network of associatons between targets according to the STRING database.



First level regulatory network of Zkscan1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_+_83779999 2.171 ENSMUST00000046168.5
 Mpped1
metallophosphoesterase domain containing 1
chr1_-_56969864 1.537 ENSMUST00000177424.1
 Satb2
special AT-rich sequence binding protein 2
chr15_-_75048837 1.346 ENSMUST00000179762.1
ENSMUST00000065408.9
 Ly6c1

lymphocyte antigen 6 complex, locus C1

chr1_-_56969827 1.127 ENSMUST00000176759.1
 Satb2
special AT-rich sequence binding protein 2
chr3_+_62338344 1.043 ENSMUST00000079300.6
 Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26
chr5_-_28210022 1.033 ENSMUST00000118882.1
 Cnpy1
canopy 1 homolog (zebrafish)
chr14_-_30353468 0.938 ENSMUST00000112249.1
 Cacna1d
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr4_+_101419277 0.837 ENSMUST00000102780.1
ENSMUST00000106946.1
ENSMUST00000106945.1
 Ak4


adenylate kinase 4


chr15_-_74997634 0.689 ENSMUST00000023248.6
 Ly6a
lymphocyte antigen 6 complex, locus A
chr8_+_72646679 0.663 ENSMUST00000161386.1
ENSMUST00000093427.4
 Nwd1

NACHT and WD repeat domain containing 1

chr5_+_64812336 0.663 ENSMUST00000166409.1
 Klf3
Kruppel-like factor 3 (basic)
chr9_-_103480328 0.640 ENSMUST00000124310.2
 Bfsp2
beaded filament structural protein 2, phakinin
chr7_+_112225856 0.634 ENSMUST00000050149.5
ENSMUST00000106647.1
ENSMUST00000106648.1
 Mical2


microtubule associated monooxygenase, calponin and LIM domain containing 2


chr8_+_72646728 0.613 ENSMUST00000161254.1
 Nwd1
NACHT and WD repeat domain containing 1
chr17_+_75005523 0.598 ENSMUST00000001927.5
 Ltbp1
latent transforming growth factor beta binding protein 1
chr5_-_28210168 0.585 ENSMUST00000117098.1
 Cnpy1
canopy 1 homolog (zebrafish)
chr12_+_73997749 0.509 ENSMUST00000110451.2
 Syt16
synaptotagmin XVI
chr18_-_52529847 0.494 ENSMUST00000171470.1
 Lox
lysyl oxidase
chr2_+_84734050 0.480 ENSMUST00000090729.2
 Ypel4
yippee-like 4 (Drosophila)
chr12_-_79007276 0.446 ENSMUST00000056660.6
ENSMUST00000174721.1
 Tmem229b

transmembrane protein 229B

chr5_-_70842617 0.439 ENSMUST00000031119.1
 Gabrg1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chr5_-_8367982 0.403 ENSMUST00000088761.4
ENSMUST00000115386.1
ENSMUST00000050166.7
ENSMUST00000046838.7
ENSMUST00000115388.2
ENSMUST00000088744.5
ENSMUST00000115385.1
 Adam22






a disintegrin and metallopeptidase domain 22






chr15_-_79164477 0.376 ENSMUST00000040019.4
 Sox10
SRY-box containing gene 10
chr17_-_33718591 0.371 ENSMUST00000174040.1
ENSMUST00000173015.1
ENSMUST00000066121.6
ENSMUST00000172767.1
ENSMUST00000173329.1
 March2




membrane-associated ring finger (C3HC4) 2




chr1_-_119837613 0.371 ENSMUST00000064091.5
 Ptpn4
protein tyrosine phosphatase, non-receptor type 4
chr1_+_171840607 0.361 ENSMUST00000136479.1
ENSMUST00000042302.6
 Cd84

CD84 antigen

chr7_-_118491912 0.361 ENSMUST00000178344.1
 Itpripl2
inositol 1,4,5-triphosphate receptor interacting protein-like 2
chr19_+_28963892 0.335 ENSMUST00000045674.2
 Ppapdc2
phosphatidic acid phosphatase type 2 domain containing 2
chr9_-_57147034 0.333 ENSMUST00000034842.4
 Neil1
nei endonuclease VIII-like 1 (E. coli)
chr12_+_88360801 0.321 ENSMUST00000166940.1
 Adck1
aarF domain containing kinase 1
chr5_+_125441546 0.296 ENSMUST00000049040.9
 Bri3bp
Bri3 binding protein
chr9_+_44499126 0.295 ENSMUST00000074989.5
 Bcl9l
B cell CLL/lymphoma 9-like
chr4_+_129960760 0.290 ENSMUST00000139884.1
 1700003M07Rik
RIKEN cDNA 1700003M07 gene
chr15_-_75111684 0.269 ENSMUST00000100542.3
 Ly6c2
lymphocyte antigen 6 complex, locus C2
chr7_-_132813528 0.259 ENSMUST00000097999.2
 Fam53b
family with sequence similarity 53, member B
chr7_-_132813715 0.254 ENSMUST00000134946.1
 Fam53b
family with sequence similarity 53, member B
chr7_-_132813799 0.254 ENSMUST00000097998.2
 Fam53b
family with sequence similarity 53, member B
chrX_+_20870166 0.245 ENSMUST00000115342.3
ENSMUST00000009530.4
 Timp1

tissue inhibitor of metalloproteinase 1

chr11_+_28853189 0.245 ENSMUST00000020759.5
 Efemp1
epidermal growth factor-containing fibulin-like extracellular matrix protein 1
chr4_-_42168603 0.222 ENSMUST00000098121.3
 Gm13305
predicted gene 13305
chr4_+_138972885 0.219 ENSMUST00000123636.1
ENSMUST00000043042.3
ENSMUST00000050949.2
 Tmco4


transmembrane and coiled-coil domains 4


chr4_-_141078302 0.213 ENSMUST00000030760.8
 Necap2
NECAP endocytosis associated 2
chr4_-_116144609 0.210 ENSMUST00000030469.4
 Lurap1
leucine rich adaptor protein 1
chr18_+_53245618 0.209 ENSMUST00000165032.1
 Snx24
sorting nexing 24
chr2_-_27248335 0.208 ENSMUST00000139312.1
 Sardh
sarcosine dehydrogenase
chr11_+_19924403 0.208 ENSMUST00000093298.5
 Spred2
sprouty-related, EVH1 domain containing 2
chr18_+_53245736 0.203 ENSMUST00000025417.8
 Snx24
sorting nexing 24
chr9_+_107580117 0.202 ENSMUST00000093785.4
 Nat6
N-acetyltransferase 6
chr4_-_133277730 0.190 ENSMUST00000105907.2
 Tmem222
transmembrane protein 222
chr11_-_47379405 0.189 ENSMUST00000077221.5
 Sgcd
sarcoglycan, delta (dystrophin-associated glycoprotein)
chr11_+_19924354 0.180 ENSMUST00000093299.6
 Spred2
sprouty-related, EVH1 domain containing 2
chr11_-_61453992 0.179 ENSMUST00000060255.7
ENSMUST00000054927.7
ENSMUST00000102661.3
 Rnf112


ring finger protein 112


chr9_+_45042425 0.167 ENSMUST00000034600.4
 Mpzl2
myelin protein zero-like 2
chr15_-_76656905 0.165 ENSMUST00000176274.1
 Cyhr1
cysteine and histidine rich 1
chr8_+_70527829 0.158 ENSMUST00000119698.1
 Fkbp8
FK506 binding protein 8
chr2_-_156839790 0.154 ENSMUST00000134838.1
ENSMUST00000137463.1
ENSMUST00000149275.2
 Gm14230


predicted gene 14230


chr19_-_61228396 0.147 ENSMUST00000076046.6
 Csf2ra
colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
chr19_+_5088534 0.146 ENSMUST00000025811.4
 Yif1a
Yip1 interacting factor homolog A (S. cerevisiae)
chr7_+_27692502 0.144 ENSMUST00000076421.6
 C030039L03Rik
RIKEN cDNA C030039L03 gene
chr17_+_45506825 0.141 ENSMUST00000024733.7
 Aars2
alanyl-tRNA synthetase 2, mitochondrial (putative)
chr4_+_141444654 0.135 ENSMUST00000006377.6
 Zbtb17
zinc finger and BTB domain containing 17
chr19_+_10525244 0.135 ENSMUST00000038379.3
 Cpsf7
cleavage and polyadenylation specific factor 7
chrX_+_164373363 0.132 ENSMUST00000033751.7
 Figf
c-fos induced growth factor
chr8_+_70527724 0.131 ENSMUST00000119353.2
ENSMUST00000075491.7
 Fkbp8

FK506 binding protein 8

chr18_-_6490808 0.124 ENSMUST00000028100.6
ENSMUST00000050542.5
 Epc1

enhancer of polycomb homolog 1 (Drosophila)

chr11_+_78512193 0.122 ENSMUST00000001127.4
 Poldip2
polymerase (DNA-directed), delta interacting protein 2
chr10_-_81545175 0.122 ENSMUST00000043604.5
 Gna11
guanine nucleotide binding protein, alpha 11
chr11_-_109722214 0.118 ENSMUST00000020938.7
 Fam20a
family with sequence similarity 20, member A
chr8_+_13037308 0.112 ENSMUST00000063820.5
ENSMUST00000033821.4
 F10

coagulation factor X

chr6_+_83711232 0.103 ENSMUST00000037807.1
 Vax2
ventral anterior homeobox containing gene 2
chr10_+_80053488 0.101 ENSMUST00000105372.1
 Gpx4
glutathione peroxidase 4
chr11_+_59662471 0.101 ENSMUST00000072031.6
ENSMUST00000116371.1
ENSMUST00000108751.1
ENSMUST00000066330.8
 Mprip



myosin phosphatase Rho interacting protein



chr2_+_55411790 0.101 ENSMUST00000155997.1
ENSMUST00000128307.1
 Gm14033

predicted gene 14033

chr12_-_111574384 0.099 ENSMUST00000180698.1
 2810029C07Rik
RIKEN cDNA 2810029C07 gene
chr16_-_10447340 0.098 ENSMUST00000051118.6
 Tvp23a
trans-golgi network vesicle protein 23A
chr11_+_120458093 0.096 ENSMUST00000058370.7
ENSMUST00000175970.1
ENSMUST00000176120.1
 Ccdc137


coiled-coil domain containing 137


chr7_-_28962223 0.090 ENSMUST00000127210.1
 Actn4
actinin alpha 4
chr12_+_116405397 0.088 ENSMUST00000084828.3
 Ncapg2
non-SMC condensin II complex, subunit G2
chr4_-_134915010 0.084 ENSMUST00000105863.1
ENSMUST00000030626.5
 Tmem50a

transmembrane protein 50A

chr19_-_45742873 0.082 ENSMUST00000026241.5
ENSMUST00000026240.7
ENSMUST00000111928.1
 Fgf8


fibroblast growth factor 8


chr2_+_156840077 0.080 ENSMUST00000081335.6
ENSMUST00000073352.3
 Tgif2

TGFB-induced factor homeobox 2

chr4_+_126262325 0.079 ENSMUST00000030660.8
 Trappc3
trafficking protein particle complex 3
chr7_-_28962265 0.078 ENSMUST00000068045.7
 Actn4
actinin alpha 4
chr19_+_53310495 0.076 ENSMUST00000003870.7
 Mxi1
Max interacting protein 1
chr7_-_45061706 0.074 ENSMUST00000107832.1
 Prrg2
proline-rich Gla (G-carboxyglutamic acid) polypeptide 2
chr17_+_24886643 0.074 ENSMUST00000117890.1
ENSMUST00000168265.1
ENSMUST00000120943.1
ENSMUST00000068508.6
ENSMUST00000119829.1
 Spsb3




splA/ryanodine receptor domain and SOCS box containing 3




chr8_-_70527645 0.072 ENSMUST00000132867.1
 Kxd1
KxDL motif containing 1
chr14_+_34673888 0.070 ENSMUST00000048263.7
 Wapal
wings apart-like homolog (Drosophila)
chr9_+_119357381 0.069 ENSMUST00000039610.8
 Xylb
xylulokinase homolog (H. influenzae)
chr6_-_122340499 0.061 ENSMUST00000160843.1
 Phc1
polyhomeotic-like 1 (Drosophila)
chr3_+_90062781 0.060 ENSMUST00000029551.2
 1700094D03Rik
RIKEN cDNA 1700094D03 gene
chr17_+_28575718 0.058 ENSMUST00000080780.6
 Lhfpl5
lipoma HMGIC fusion partner-like 5
chr19_+_3767953 0.057 ENSMUST00000113970.1
 Suv420h1
suppressor of variegation 4-20 homolog 1 (Drosophila)
chr11_+_69981127 0.039 ENSMUST00000108593.1
 Ctdnep1
CTD nuclear envelope phosphatase 1
chr15_-_78572754 0.033 ENSMUST00000043214.6
 Rac2
RAS-related C3 botulinum substrate 2
chr1_+_87326997 0.031 ENSMUST00000027475.8
 Gigyf2
GRB10 interacting GYF protein 2
chr10_-_39122277 0.026 ENSMUST00000136546.1
 Fam229b
family with sequence similarity 229, member B
chr12_-_72664759 0.020 ENSMUST00000021512.9
 Dhrs7
dehydrogenase/reductase (SDR family) member 7
chr2_+_27676440 0.012 ENSMUST00000129514.1
 Rxra
retinoid X receptor alpha
chr11_-_69981242 0.011 ENSMUST00000108594.1
 Elp5
elongator acetyltransferase complex subunit 5
chr6_-_122340525 0.011 ENSMUST00000112600.2
 Phc1
polyhomeotic-like 1 (Drosophila)
chr19_+_53903351 0.011 ENSMUST00000025931.6
ENSMUST00000165617.1
 Pdcd4

programmed cell death 4

chr8_-_70527945 0.010 ENSMUST00000138260.1
ENSMUST00000117580.1
 Kxd1

KxDL motif containing 1

chr11_-_120457936 0.009 ENSMUST00000137632.1
ENSMUST00000044007.2
 Oxld1

oxidoreductase like domain containing 1

chr8_+_4253067 0.005 ENSMUST00000011981.3
 Snapc2
small nuclear RNA activating complex, polypeptide 2
chr4_-_47057296 0.001 ENSMUST00000107747.1
ENSMUST00000084616.2
 Anks6

ankyrin repeat and sterile alpha motif domain containing 6


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.2 2.7 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 0.6 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 0.4 GO:2001180 negative regulation of interleukin-18 production(GO:0032701) negative regulation of interleukin-10 secretion(GO:2001180)
0.1 0.2 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.1 0.3 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.1 0.5 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.2 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.0 1.0 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.4 GO:0032808 lacrimal gland development(GO:0032808)
0.0 0.6 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.1 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.8 GO:0046033 AMP metabolic process(GO:0046033)
0.0 0.1 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.4 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.2 GO:1903975 regulation of glial cell migration(GO:1903975)
0.0 0.1 GO:0042732 D-xylose metabolic process(GO:0042732)
0.0 0.6 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 0.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.2 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.4 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.1 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011)
0.0 0.1 GO:0035509 negative regulation of myosin-light-chain-phosphatase activity(GO:0035509)
0.0 0.4 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.1 0.9 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.4 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.4 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 2.3 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 2.3 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.0 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.2 GO:0031143 pseudopodium(GO:0031143)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.2 0.5 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.2 0.9 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.1 0.6 GO:0050436 microfibril binding(GO:0050436)
0.1 0.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.2 GO:0046997 sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.1 0.4 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.6 GO:0052872 3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) phenanthrene 9,10-monooxygenase activity(GO:0018636) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) tocotrienol omega-hydroxylase activity(GO:0052872) thalianol hydroxylase activity(GO:0080014)
0.1 0.4 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 2.2 GO:0044824 integrase activity(GO:0008907) T/G mismatch-specific endonuclease activity(GO:0043765) retroviral integrase activity(GO:0044823) retroviral 3' processing activity(GO:0044824)
0.0 0.1 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.0 0.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.3 GO:0070636 single-strand selective uracil DNA N-glycosylase activity(GO:0017065) nicotinamide riboside hydrolase activity(GO:0070635) nicotinic acid riboside hydrolase activity(GO:0070636) deoxyribonucleoside 5'-monophosphate N-glycosidase activity(GO:0070694)
0.0 0.4 GO:0050811 GABA-A receptor activity(GO:0004890) GABA receptor binding(GO:0050811)
0.0 0.3 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
0.0 0.1 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)