Motif ID: Klf6_Patz1

Z-value: 0.933

Transcription factors associated with Klf6_Patz1:

Gene SymbolEntrez IDGene Name
Klf6 ENSMUSG00000000078.6 Klf6
Patz1 ENSMUSG00000020453.11 Patz1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Patz1mm10_v2_chr11_+_3289880_32899930.574.6e-03Click!
Klf6mm10_v2_chr13_+_5861489_58615010.184.1e-01Click!


Activity profile for motif Klf6_Patz1.

activity profile for motif Klf6_Patz1


Sorted Z-values histogram for motif Klf6_Patz1

Sorted Z-values for motif Klf6_Patz1



Network of associatons between targets according to the STRING database.



First level regulatory network of Klf6_Patz1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_+_119402444 1.981 ENSMUST00000035093.8
ENSMUST00000165044.1
 Acvr2b

activin receptor IIB

chr7_+_44310213 1.958 ENSMUST00000107938.1
 Shank1
SH3/ankyrin domain gene 1
chrX_+_13071470 1.814 ENSMUST00000169594.2
 Usp9x
ubiquitin specific peptidase 9, X chromosome
chr7_-_34812677 1.790 ENSMUST00000078686.6
 Chst8
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
chr3_-_8667033 1.759 ENSMUST00000042412.3
 Hey1
hairy/enhancer-of-split related with YRPW motif 1
chr17_+_26941420 1.674 ENSMUST00000081285.3
ENSMUST00000177932.1
 Syngap1

synaptic Ras GTPase activating protein 1 homolog (rat)

chr17_+_28142267 1.616 ENSMUST00000043503.3
 Scube3
signal peptide, CUB domain, EGF-like 3
chr13_-_56252163 1.616 ENSMUST00000058475.4
 Neurog1
neurogenin 1
chr11_-_95587691 1.557 ENSMUST00000000122.6
 Ngfr
nerve growth factor receptor (TNFR superfamily, member 16)
chr6_-_119848093 1.547 ENSMUST00000079582.4
 Erc1
ELKS/RAB6-interacting/CAST family member 1
chr11_+_119942763 1.513 ENSMUST00000026436.3
ENSMUST00000106231.1
ENSMUST00000075180.5
ENSMUST00000103021.3
ENSMUST00000106233.1
 Baiap2




brain-specific angiogenesis inhibitor 1-associated protein 2




chr7_+_36698002 1.513 ENSMUST00000021641.6
 Tshz3
teashirt zinc finger family member 3
chr4_+_116877376 1.474 ENSMUST00000044823.3
 Zswim5
zinc finger SWIM-type containing 5
chr5_-_25498748 1.434 ENSMUST00000173174.1
 Kmt2c
lysine (K)-specific methyltransferase 2C
chr12_-_27342696 1.373 ENSMUST00000079063.5
 Sox11
SRY-box containing gene 11
chr7_+_29289300 1.346 ENSMUST00000048187.4
 Ppp1r14a
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr5_-_25498702 1.338 ENSMUST00000173073.1
ENSMUST00000045291.7
 Kmt2c

lysine (K)-specific methyltransferase 2C

chr6_-_119848059 1.330 ENSMUST00000184864.1
 Erc1
ELKS/RAB6-interacting/CAST family member 1
chr10_-_127620960 1.323 ENSMUST00000121829.1
 Lrp1
low density lipoprotein receptor-related protein 1
chr1_-_172057573 1.316 ENSMUST00000059794.3
 Nhlh1
nescient helix loop helix 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 605 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 3.5 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.2 3.2 GO:0048617 embryonic foregut morphogenesis(GO:0048617)
0.1 2.8 GO:0006284 base-excision repair(GO:0006284)
0.7 2.7 GO:0021698 cerebellar cortex structural organization(GO:0021698)
0.2 2.6 GO:2000821 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688) regulation of grooming behavior(GO:2000821)
0.5 2.4 GO:2000587 regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.7 2.0 GO:0046959 habituation(GO:0046959)
0.2 2.0 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.1 1.9 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.2 1.8 GO:0035608 protein deglutamylation(GO:0035608)
0.2 1.8 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.1 1.8 GO:0051764 actin crosslink formation(GO:0051764)
0.1 1.8 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.1 1.8 GO:0007520 myoblast fusion(GO:0007520)
0.6 1.7 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
0.3 1.7 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.2 1.7 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.1 1.7 GO:0071625 vocalization behavior(GO:0071625)
0.5 1.6 GO:0060489 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105) orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.3 1.6 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 181 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.2 GO:0005905 clathrin-coated pit(GO:0005905)
0.3 3.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 3.1 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 3.0 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 3.0 GO:0045211 postsynaptic membrane(GO:0045211)
0.2 2.8 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 2.6 GO:0098794 postsynapse(GO:0098794)
0.1 2.4 GO:0071565 nBAF complex(GO:0071565)
0.1 2.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 2.0 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 2.0 GO:0031225 anchored component of membrane(GO:0031225)
0.1 1.9 GO:0001741 XY body(GO:0001741)
0.1 1.9 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.9 GO:0016605 PML body(GO:0016605)
0.1 1.8 GO:0043034 costamere(GO:0043034)
0.4 1.6 GO:0060187 cell pole(GO:0060187)
0.2 1.6 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 1.6 GO:1990391 DNA repair complex(GO:1990391)
0.2 1.5 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 1.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 302 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 6.5 GO:0017137 Rab GTPase binding(GO:0017137)
0.2 5.1 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 3.7 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.2 3.5 GO:0034185 apolipoprotein binding(GO:0034185)
0.3 2.9 GO:0048185 activin binding(GO:0048185)
0.7 2.6 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.3 2.6 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.3 2.6 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 2.6 GO:0034930 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131)
0.0 2.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 2.1 GO:0070064 proline-rich region binding(GO:0070064)
0.0 2.1 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 2.0 GO:0042162 telomeric DNA binding(GO:0042162)
0.3 1.9 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 1.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 1.8 GO:0046790 virion binding(GO:0046790)
0.1 1.8 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 1.8 GO:0003777 microtubule motor activity(GO:0003777)
0.2 1.7 GO:0051718 DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.2 1.7 GO:0030957 Tat protein binding(GO:0030957)