Motif ID: Meox2

Z-value: 0.665


Transcription factors associated with Meox2:

Gene SymbolEntrez IDGene Name
Meox2 ENSMUSG00000036144.5 Meox2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Meox2mm10_v2_chr12_+_37108533_371085460.311.5e-01Click!


Activity profile for motif Meox2.

activity profile for motif Meox2


Sorted Z-values histogram for motif Meox2

Sorted Z-values for motif Meox2



Network of associatons between targets according to the STRING database.



First level regulatory network of Meox2

PNG image of the network

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Top targets:


Showing 1 to 20 of 145 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_+_42907563 3.789 ENSMUST00000151244.1
ENSMUST00000114694.2
 Zbtb20

zinc finger and BTB domain containing 20

chr14_+_26259109 1.791 ENSMUST00000174494.1
 Duxbl3
double homeobox B-like 3
chr14_+_26119811 1.723 ENSMUST00000173617.1
 Duxbl2
doubl homeobox B-like 2
chr14_+_25980039 1.714 ENSMUST00000173155.1
 Duxbl1
double homeobox B-like 1
chr17_+_75005523 1.554 ENSMUST00000001927.5
 Ltbp1
latent transforming growth factor beta binding protein 1
chr10_-_116972609 1.423 ENSMUST00000092165.4
 Gm10271
predicted gene 10271
chr3_+_66219909 1.422 ENSMUST00000029421.5
 Ptx3
pentraxin related gene
chr8_+_66386292 1.403 ENSMUST00000039540.5
ENSMUST00000110253.2
 March1

membrane-associated ring finger (C3HC4) 1

chr5_-_62766153 1.321 ENSMUST00000076623.4
 Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr15_-_74752963 1.138 ENSMUST00000023259.8
 Lynx1
Ly6/neurotoxin 1
chr19_-_9559204 1.069 ENSMUST00000090527.3
 Stxbp3b
syntaxin-binding protein 3B
chr11_-_80377975 1.068 ENSMUST00000179332.1
ENSMUST00000103225.4
ENSMUST00000134274.1
 5730455P16Rik


RIKEN cDNA 5730455P16 gene


chr2_+_120629113 1.030 ENSMUST00000150912.1
ENSMUST00000180041.1
 Stard9

START domain containing 9

chr3_-_54714353 1.002 ENSMUST00000178832.1
 Gm21958
predicted gene, 21958
chr13_-_77131276 0.986 ENSMUST00000159300.1
 Ankrd32
ankyrin repeat domain 32
chr12_+_84069325 0.966 ENSMUST00000046422.4
ENSMUST00000072505.4
 Acot5

acyl-CoA thioesterase 5

chr9_+_21927471 0.953 ENSMUST00000170304.1
ENSMUST00000006403.6
 Ccdc159

coiled-coil domain containing 159

chr3_+_14533788 0.933 ENSMUST00000108370.2
 Lrrcc1
leucine rich repeat and coiled-coil domain containing 1
chr4_+_146654927 0.913 ENSMUST00000070932.3
 Gm13248
predicted gene 13248
chr10_-_53647080 0.888 ENSMUST00000169866.1
 Fam184a
family with sequence similarity 184, member A

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 48 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.8 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 2.4 GO:0045580 regulation of T cell differentiation(GO:0045580)
0.1 1.6 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.5 1.4 GO:0008228 opsonization(GO:0008228) modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.1 1.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.2 1.0 GO:0032788 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.1 1.0 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 1.0 GO:0051225 spindle assembly(GO:0051225)
0.0 0.9 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.2 0.8 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.0 0.8 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.0 0.8 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 0.7 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 0.7 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.2 0.6 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.2 0.6 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.1 0.6 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 0.6 GO:0051775 response to redox state(GO:0051775)
0.2 0.5 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.0 0.5 GO:0032467 positive regulation of cytokinesis(GO:0032467)

Gene overrepresentation in cellular_component category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.2 GO:0070469 respiratory chain(GO:0070469)
0.5 1.6 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.0 1.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.9 GO:0005871 kinesin complex(GO:0005871)
0.0 0.5 GO:0005844 polysome(GO:0005844)
0.0 0.4 GO:0045275 respiratory chain complex III(GO:0045275)
0.0 0.4 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.3 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 0.3 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.3 GO:0030478 actin cap(GO:0030478)
0.0 0.3 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0000138 Golgi trans cisterna(GO:0000138)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.7 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 2.4 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.4 1.6 GO:0050436 microfibril binding(GO:0050436)
0.3 1.4 GO:0001849 complement component C1q binding(GO:0001849)
0.1 1.1 GO:0042287 MHC protein binding(GO:0042287)
0.0 1.1 GO:0008200 ion channel inhibitor activity(GO:0008200)
0.0 1.1 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 1.0 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.8 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.6 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.6 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.6 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 0.4 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1 0.4 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.4 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.4 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.3 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.3 GO:0005523 tropomyosin binding(GO:0005523)