Motif ID: Zbtb4

Z-value: 0.666


Transcription factors associated with Zbtb4:

Gene SymbolEntrez IDGene Name
Zbtb4 ENSMUSG00000018750.8 Zbtb4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zbtb4mm10_v2_chr11_+_69765899_69765925-0.631.2e-03Click!


Activity profile for motif Zbtb4.

activity profile for motif Zbtb4


Sorted Z-values histogram for motif Zbtb4

Sorted Z-values for motif Zbtb4



Network of associatons between targets according to the STRING database.



First level regulatory network of Zbtb4

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_139543889 4.149 ENSMUST00000174792.1
ENSMUST00000031523.8
 Uncx

UNC homeobox

chr6_+_47244359 3.586 ENSMUST00000060839.6
 Cntnap2
contactin associated protein-like 2
chr5_+_147957310 1.512 ENSMUST00000085558.4
ENSMUST00000129092.1
 Mtus2

microtubule associated tumor suppressor candidate 2

chrX_+_103422010 1.450 ENSMUST00000182089.1
 Gm26992
predicted gene, 26992
chr1_+_72824482 1.356 ENSMUST00000047328.4
 Igfbp2
insulin-like growth factor binding protein 2
chr6_+_48841633 1.318 ENSMUST00000168406.1
 Tmem176a
transmembrane protein 176A
chr6_+_48841476 1.304 ENSMUST00000101426.4
 Tmem176a
transmembrane protein 176A
chr4_-_135971894 1.276 ENSMUST00000105852.1
 Lypla2
lysophospholipase 2
chr6_-_48841373 1.208 ENSMUST00000166247.1
 Tmem176b
transmembrane protein 176B
chr14_-_30626196 1.169 ENSMUST00000112210.3
ENSMUST00000112211.2
ENSMUST00000112208.1
 Prkcd


protein kinase C, delta


chr12_-_45074112 1.130 ENSMUST00000120531.1
ENSMUST00000143376.1
 Stxbp6

syntaxin binding protein 6 (amisyn)

chr8_-_57962564 1.102 ENSMUST00000098757.3
 Galntl6
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6
chr19_+_41482632 1.043 ENSMUST00000067795.5
 Lcor
ligand dependent nuclear receptor corepressor
chr8_-_122678653 1.028 ENSMUST00000134045.1
 Cbfa2t3
core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)
chr12_-_45074457 1.008 ENSMUST00000053768.6
 Stxbp6
syntaxin binding protein 6 (amisyn)
chr6_-_48841098 0.984 ENSMUST00000101429.4
 Tmem176b
transmembrane protein 176B
chr7_-_25005895 0.982 ENSMUST00000102858.3
ENSMUST00000080882.6
 Atp1a3

ATPase, Na+/K+ transporting, alpha 3 polypeptide

chr7_-_140102367 0.974 ENSMUST00000142105.1
 Fuom
fucose mutarotase
chr1_-_175692624 0.955 ENSMUST00000027809.7
 Opn3
opsin 3
chr9_+_75071386 0.924 ENSMUST00000155282.2
 Myo5a
myosin VA

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 85 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 4.8 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.5 4.1 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.7 3.6 GO:0071205 clustering of voltage-gated potassium channels(GO:0045163) protein localization to juxtaparanode region of axon(GO:0071205)
0.5 2.6 GO:2000325 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.6 2.5 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.3 2.4 GO:0006004 fucose metabolic process(GO:0006004)
0.3 2.1 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.1 1.9 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.1 1.8 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.2 1.3 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.1 1.3 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.2 1.2 GO:0006680 glucosylceramide catabolic process(GO:0006680) negative regulation of filopodium assembly(GO:0051490)
0.3 1.0 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 1.0 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.1 1.0 GO:0036376 sodium ion export from cell(GO:0036376)
0.3 0.9 GO:0006657 CDP-choline pathway(GO:0006657)
0.2 0.9 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1 0.9 GO:0032796 uropod organization(GO:0032796)
0.1 0.9 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.8 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-dependent nucleosome organization(GO:0034723) DNA replication-independent nucleosome organization(GO:0034724)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 3.6 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.8 2.5 GO:0042642 actomyosin, myosin complex part(GO:0042642)
0.0 2.5 GO:0016607 nuclear speck(GO:0016607)
0.1 2.1 GO:0000145 exocyst(GO:0000145)
0.0 1.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 1.0 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) dendritic spine neck(GO:0044326)
0.1 1.0 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.9 GO:0042587 glycogen granule(GO:0042587)
0.0 0.9 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.7 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 0.5 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.5 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 0.4 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0 0.4 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.0 0.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.4 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.3 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.3 GO:0005697 telomerase holoenzyme complex(GO:0005697)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 63 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.7 GO:0002020 protease binding(GO:0002020)
0.1 2.6 GO:0032183 SUMO binding(GO:0032183)
0.2 2.5 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.6 2.4 GO:0042806 fucose binding(GO:0042806)
0.1 2.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 1.8 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.2 1.4 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 1.3 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.3 1.2 GO:0070976 calcium-independent protein kinase C activity(GO:0004699) TIR domain binding(GO:0070976)
0.1 1.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.3 1.0 GO:0009881 photoreceptor activity(GO:0009881)
0.1 1.0 GO:0103116 alpha-D-galactofuranose transporter activity(GO:0103116)
0.2 0.9 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2 0.9 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.9 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.9 GO:0034930 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131)
0.0 0.9 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2 0.7 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.1 0.7 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733)
0.1 0.7 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)