Motif ID: Barhl2

Z-value: 0.555


Transcription factors associated with Barhl2:

Gene SymbolEntrez IDGene Name
Barhl2 ENSMUSG00000034384.10 Barhl2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Barhl2mm10_v2_chr5_-_106458440_106458470-0.738.5e-05Click!


Activity profile for motif Barhl2.

activity profile for motif Barhl2


Sorted Z-values histogram for motif Barhl2

Sorted Z-values for motif Barhl2



Network of associatons between targets according to the STRING database.



First level regulatory network of Barhl2

PNG image of the network

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Top targets:


Showing 1 to 20 of 131 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_101377897 2.768 ENSMUST00000075994.6
 Pdzrn3
PDZ domain containing RING finger 3
chr16_-_22439719 2.432 ENSMUST00000079601.6
 Etv5
ets variant gene 5
chr3_-_80802789 2.345 ENSMUST00000107745.1
ENSMUST00000075316.4
 Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr12_-_34528844 1.935 ENSMUST00000110819.2
 Hdac9
histone deacetylase 9
chr5_-_110839575 1.898 ENSMUST00000145318.1
 Hscb
HscB iron-sulfur cluster co-chaperone homolog (E. coli)
chr6_+_125552948 1.534 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
 Vwf


Von Willebrand factor homolog


chr1_+_165788681 1.466 ENSMUST00000161971.1
ENSMUST00000178336.1
ENSMUST00000005907.5
ENSMUST00000027849.4
 Cd247



CD247 antigen



chr3_-_49757257 1.425 ENSMUST00000035931.7
 Pcdh18
protocadherin 18
chr17_-_49564262 1.397 ENSMUST00000057610.6
 Daam2
dishevelled associated activator of morphogenesis 2
chr5_-_110839757 1.231 ENSMUST00000056937.5
 Hscb
HscB iron-sulfur cluster co-chaperone homolog (E. coli)
chr14_+_30825580 1.194 ENSMUST00000006701.5
 Tmem110
transmembrane protein 110
chr1_+_165788746 1.171 ENSMUST00000161559.2
 Cd247
CD247 antigen
chr16_-_22439570 1.140 ENSMUST00000170393.1
 Etv5
ets variant gene 5
chrX_+_71663665 1.124 ENSMUST00000070449.5
 Gpr50
G-protein-coupled receptor 50
chr18_-_78206408 1.090 ENSMUST00000163367.1
 Slc14a2
solute carrier family 14 (urea transporter), member 2
chr14_-_88471396 1.086 ENSMUST00000061628.5
 Pcdh20
protocadherin 20
chr18_+_61045139 1.078 ENSMUST00000025522.4
ENSMUST00000115274.1
 Pdgfrb

platelet derived growth factor receptor, beta polypeptide

chr1_-_163725123 1.017 ENSMUST00000159679.1
 Mettl11b
methyltransferase like 11B
chr11_+_85832551 0.959 ENSMUST00000000095.6
 Tbx2
T-box 2
chr5_-_37824580 0.946 ENSMUST00000063116.9
 Msx1
msh homeobox 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 50 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 3.6 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.2 3.1 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 2.8 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 2.6 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.1 2.0 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.2 1.9 GO:0034983 peptidyl-lysine deacetylation(GO:0034983) regulation of skeletal muscle fiber development(GO:0048742)
0.5 1.6 GO:0072223 metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262)
0.5 1.6 GO:0002447 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308) regulation of eosinophil activation(GO:1902566)
0.2 1.6 GO:0015808 L-alanine transport(GO:0015808)
0.0 1.5 GO:0030168 platelet activation(GO:0030168)
0.1 1.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.2 1.1 GO:0015840 urea transport(GO:0015840) urea transmembrane transport(GO:0071918)
0.1 1.1 GO:2000809 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) positive regulation of synaptic vesicle clustering(GO:2000809)
0.3 1.0 GO:0007521 muscle cell fate determination(GO:0007521) mammary placode formation(GO:0060596)
0.0 1.0 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.3 0.9 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.3 0.9 GO:0008065 establishment of blood-nerve barrier(GO:0008065) regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 0.9 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.2 0.8 GO:1902990 mitotic telomere maintenance via semi-conservative replication(GO:1902990) negative regulation of t-circle formation(GO:1904430)
0.2 0.8 GO:0070384 Harderian gland development(GO:0070384)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.8 GO:0031594 neuromuscular junction(GO:0031594)
0.7 2.6 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 2.3 GO:0032279 asymmetric synapse(GO:0032279)
0.3 2.1 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 1.9 GO:0005882 intermediate filament(GO:0005882)
0.0 1.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.3 1.5 GO:0033093 Weibel-Palade body(GO:0033093)
0.2 1.1 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.9 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 0.7 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.5 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.1 0.4 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.4 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.4 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.3 GO:0000235 astral microtubule(GO:0000235)
0.0 0.3 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 0.2 GO:0000802 transverse filament(GO:0000802)
0.0 0.2 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 34 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.1 GO:0051087 chaperone binding(GO:0051087)
0.4 2.3 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 1.9 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.4 1.6 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.2 1.6 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) L-proline transmembrane transporter activity(GO:0015193) alanine transmembrane transporter activity(GO:0022858)
0.2 1.5 GO:0019865 immunoglobulin binding(GO:0019865)
0.4 1.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.2 1.1 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.2 1.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 1.1 GO:0015265 urea channel activity(GO:0015265)
0.1 0.9 GO:0017166 dystroglycan binding(GO:0002162) vinculin binding(GO:0017166)
0.0 0.9 GO:0002039 p53 binding(GO:0002039)
0.1 0.8 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 0.8 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.8 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 0.7 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.6 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.6 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.5 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.5 GO:0019784 NEDD8-specific protease activity(GO:0019784)