Motif ID: Trp73

Z-value: 0.547


Transcription factors associated with Trp73:

Gene SymbolEntrez IDGene Name
Trp73 ENSMUSG00000029026.10 Trp73

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Trp73mm10_v2_chr4_-_154097105_1540971730.556.4e-03Click!


Activity profile for motif Trp73.

activity profile for motif Trp73


Sorted Z-values histogram for motif Trp73

Sorted Z-values for motif Trp73



Network of associatons between targets according to the STRING database.



First level regulatory network of Trp73

PNG image of the network

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Top targets:


Showing 1 to 20 of 76 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_153665274 2.121 ENSMUST00000152114.1
ENSMUST00000111812.1
 Rgs8

regulator of G-protein signaling 8

chr16_-_17125106 1.847 ENSMUST00000093336.6
 2610318N02Rik
RIKEN cDNA 2610318N02 gene
chr17_+_29090969 1.823 ENSMUST00000119901.1
 Cdkn1a
cyclin-dependent kinase inhibitor 1A (P21)
chr13_+_48261427 1.740 ENSMUST00000021810.1
 Id4
inhibitor of DNA binding 4
chr7_-_141443314 1.474 ENSMUST00000106005.2
 Lrdd
leucine-rich and death domain containing
chr12_+_109747903 1.469 ENSMUST00000183084.1
ENSMUST00000182300.1
 Mirg

miRNA containing gene

chr1_+_72824482 1.453 ENSMUST00000047328.4
 Igfbp2
insulin-like growth factor binding protein 2
chr12_-_45074112 1.194 ENSMUST00000120531.1
ENSMUST00000143376.1
 Stxbp6

syntaxin binding protein 6 (amisyn)

chrX_-_10216918 1.156 ENSMUST00000072393.2
ENSMUST00000044598.6
ENSMUST00000073392.4
ENSMUST00000115533.1
ENSMUST00000115532.1
 Rpgr




retinitis pigmentosa GTPase regulator




chr2_-_164857542 1.144 ENSMUST00000109316.1
ENSMUST00000156255.1
ENSMUST00000128110.1
ENSMUST00000109317.3
 Pltp



phospholipid transfer protein



chrX_+_10717390 1.139 ENSMUST00000115524.1
ENSMUST00000008179.6
 Mid1ip1

Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish))

chr3_+_159839729 1.133 ENSMUST00000068952.5
 Wls
wntless homolog (Drosophila)
chr15_+_84232030 1.049 ENSMUST00000023072.6
 Parvb
parvin, beta
chrX_+_10717451 1.047 ENSMUST00000156321.1
 Mid1ip1
Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish))
chr11_-_76468396 0.961 ENSMUST00000065028.7
 Abr
active BCR-related gene
chr2_-_164857671 0.886 ENSMUST00000059954.7
 Pltp
phospholipid transfer protein
chr12_-_45074457 0.801 ENSMUST00000053768.6
 Stxbp6
syntaxin binding protein 6 (amisyn)
chr10_-_67912620 0.710 ENSMUST00000064656.7
 Zfp365
zinc finger protein 365
chr9_-_109082372 0.696 ENSMUST00000167504.1
 Tma7
translational machinery associated 7 homolog (S. cerevisiae)
chr5_+_43233928 0.643 ENSMUST00000114066.1
ENSMUST00000114065.1
 Cpeb2

cytoplasmic polyadenylation element binding protein 2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 36 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.2 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.2 2.1 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.5 2.0 GO:0042360 vitamin E metabolic process(GO:0042360)
0.2 2.0 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.2 1.8 GO:0071493 cellular response to UV-B(GO:0071493) replicative senescence(GO:0090399)
0.4 1.7 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.1 1.5 GO:0042104 positive regulation of activated T cell proliferation(GO:0042104)
0.0 1.2 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.1 1.1 GO:0031017 exocrine pancreas development(GO:0031017)
0.2 1.0 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.0 1.0 GO:0030032 lamellipodium assembly(GO:0030032)
0.2 0.7 GO:0033566 gamma-tubulin complex localization(GO:0033566)
0.2 0.6 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.1 0.6 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.1 0.6 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.0 0.5 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 0.5 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.5 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.5 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.1 0.4 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)

Gene overrepresentation in cellular_component category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.0 GO:0000145 exocyst(GO:0000145)
0.6 1.8 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 1.5 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 1.2 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.9 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.7 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.4 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.4 GO:0043034 costamere(GO:0043034)
0.1 0.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.2 GO:0000811 GINS complex(GO:0000811)
0.0 0.2 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.2 GO:0005915 zonula adherens(GO:0005915)
0.0 0.2 GO:0045180 basal cortex(GO:0045180)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.1 GO:0031105 septin complex(GO:0031105)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 2.0 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 1.9 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.1 1.8 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.2 1.5 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 1.1 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.1 0.6 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.6 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.1 0.5 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.5 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 0.4 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.4 GO:0051787 misfolded protein binding(GO:0051787)
0.1 0.3 GO:0043559 insulin binding(GO:0043559)
0.0 0.3 GO:0008483 transaminase activity(GO:0008483)
0.0 0.2 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.2 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.1 GO:1990932 5.8S rRNA binding(GO:1990932)