Motif ID: Bhlhe40

Z-value: 0.494


Transcription factors associated with Bhlhe40:

Gene SymbolEntrez IDGene Name
Bhlhe40 ENSMUSG00000030103.5 Bhlhe40

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Bhlhe40mm10_v2_chr6_+_108660616_108660682-0.621.7e-03Click!


Activity profile for motif Bhlhe40.

activity profile for motif Bhlhe40


Sorted Z-values histogram for motif Bhlhe40

Sorted Z-values for motif Bhlhe40



Network of associatons between targets according to the STRING database.



First level regulatory network of Bhlhe40

PNG image of the network

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Top targets:


Showing 1 to 20 of 87 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_148039035 1.133 ENSMUST00000097788.4
 Mthfr
5,10-methylenetetrahydrofolate reductase
chr7_+_35802593 1.075 ENSMUST00000052454.2
 E130304I02Rik
RIKEN cDNA E130304I02 gene
chr4_+_148039097 1.034 ENSMUST00000141283.1
 Mthfr
5,10-methylenetetrahydrofolate reductase
chr7_+_121707189 0.953 ENSMUST00000065310.2
 1700069B07Rik
RIKEN cDNA 1700069B07 gene
chr11_+_97450136 0.818 ENSMUST00000107601.1
 Arhgap23
Rho GTPase activating protein 23
chr1_-_75219245 0.655 ENSMUST00000079464.6
 Tuba4a
tubulin, alpha 4A
chr2_+_84839395 0.616 ENSMUST00000146816.1
ENSMUST00000028469.7
 Slc43a1

solute carrier family 43, member 1

chr19_-_4201591 0.595 ENSMUST00000025740.6
 Rad9a
RAD9 homolog A
chrX_+_136270253 0.594 ENSMUST00000178632.1
ENSMUST00000053540.4
 Ngfrap1

nerve growth factor receptor (TNFRSF16) associated protein 1

chr12_-_3426700 0.563 ENSMUST00000180149.1
 1110002L01Rik
RIKEN cDNA 1110002L01 gene
chr16_+_8830093 0.532 ENSMUST00000023150.5
 1810013L24Rik
RIKEN cDNA 1810013L24 gene
chr17_-_12769605 0.525 ENSMUST00000024599.7
 Igf2r
insulin-like growth factor 2 receptor
chr11_-_94653964 0.491 ENSMUST00000039949.4
 Eme1
essential meiotic endonuclease 1 homolog 1 (S. pombe)
chr12_+_86947343 0.487 ENSMUST00000038369.4
 2310044G17Rik
RIKEN cDNA 2310044G17 gene
chr1_+_166254095 0.450 ENSMUST00000111416.1
 Ildr2
immunoglobulin-like domain containing receptor 2
chrX_+_136270302 0.443 ENSMUST00000113112.1
 Ngfrap1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr10_-_18023229 0.418 ENSMUST00000020002.7
 Abracl
ABRA C-terminal like
chr4_-_137048695 0.412 ENSMUST00000049583.7
 Zbtb40
zinc finger and BTB domain containing 40
chr16_-_44139003 0.393 ENSMUST00000124102.1
 Atp6v1a
ATPase, H+ transporting, lysosomal V1 subunit A
chr2_-_37422869 0.391 ENSMUST00000112936.1
ENSMUST00000112934.1
 Rc3h2

ring finger and CCCH-type zinc finger domains 2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 25 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 2.2 GO:0070829 heterochromatin maintenance(GO:0070829)
0.0 1.0 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.0 0.8 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.1 0.6 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.6 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.6 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.1 0.5 GO:0072429 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423) response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0 0.5 GO:1902476 chloride transmembrane transport(GO:1902476)
0.1 0.4 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.4 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 0.4 GO:0001675 acrosome assembly(GO:0001675)
0.1 0.3 GO:2000508 regulation of dendritic cell chemotaxis(GO:2000508) positive regulation of dendritic cell chemotaxis(GO:2000510)
0.1 0.3 GO:0071873 response to norepinephrine(GO:0071873)
0.1 0.3 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.1 0.3 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) myotome development(GO:0061055)
0.0 0.3 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 0.2 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 0.2 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.2 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)

Gene overrepresentation in cellular_component category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.8 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 0.7 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.6 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 0.5 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.5 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.4 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 0.3 GO:1990037 Lewy body core(GO:1990037)
0.0 0.3 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 0.3 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 0.2 GO:0032280 symmetric synapse(GO:0032280)
0.0 0.2 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.2 GO:0071439 clathrin complex(GO:0071439)
0.0 0.2 GO:0000800 lateral element(GO:0000800)
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)

Gene overrepresentation in molecular_function category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 2.2 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 1.0 GO:0005123 death receptor binding(GO:0005123)
0.0 0.8 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 0.6 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.6 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 0.5 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 0.4 GO:0015173 hydrogen:amino acid symporter activity(GO:0005280) aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.3 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 0.2 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 0.2 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.2 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.0 0.1 GO:0030976 thiamine pyrophosphate binding(GO:0030976)