Motif ID: Irf4

Z-value: 0.708


Transcription factors associated with Irf4:

Gene SymbolEntrez IDGene Name
Irf4 ENSMUSG00000021356.3 Irf4



Activity profile for motif Irf4.

activity profile for motif Irf4


Sorted Z-values histogram for motif Irf4

Sorted Z-values for motif Irf4



Network of associatons between targets according to the STRING database.



First level regulatory network of Irf4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_77894096 3.208 ENSMUST00000017597.4
Pipox
pipecolic acid oxidase
chr8_+_84723003 2.546 ENSMUST00000098571.4
G430095P16Rik
RIKEN cDNA G430095P16 gene
chr3_+_90537306 2.240 ENSMUST00000107335.1
S100a16
S100 calcium binding protein A16
chr3_+_90537242 2.199 ENSMUST00000098911.3
S100a16
S100 calcium binding protein A16
chr6_-_39118211 2.059 ENSMUST00000038398.6
Parp12
poly (ADP-ribose) polymerase family, member 12
chr17_-_6782775 2.058 ENSMUST00000064234.6
Ezr
ezrin
chr17_-_81649607 1.931 ENSMUST00000163680.2
ENSMUST00000086538.3
ENSMUST00000163123.1
Slc8a1


solute carrier family 8 (sodium/calcium exchanger), member 1


chr1_-_163313661 1.909 ENSMUST00000174397.1
ENSMUST00000075805.6
ENSMUST00000027878.7
Prrx1


paired related homeobox 1


chr1_-_97977233 1.793 ENSMUST00000161567.1
Pam
peptidylglycine alpha-amidating monooxygenase
chr9_-_116175318 1.776 ENSMUST00000061101.4
ENSMUST00000035014.6
Tgfbr2

transforming growth factor, beta receptor II

chr8_-_84773381 1.776 ENSMUST00000109764.1
Nfix
nuclear factor I/X
chr1_-_14310198 1.731 ENSMUST00000168081.2
ENSMUST00000027066.6
Eya1

eyes absent 1 homolog (Drosophila)

chr16_+_43235856 1.566 ENSMUST00000146708.1
Zbtb20
zinc finger and BTB domain containing 20
chr6_-_87335758 1.565 ENSMUST00000042025.9
Antxr1
anthrax toxin receptor 1
chr1_+_16688405 1.539 ENSMUST00000026881.4
Ly96
lymphocyte antigen 96
chr5_-_104021919 1.525 ENSMUST00000031251.9
Hsd17b11
hydroxysteroid (17-beta) dehydrogenase 11
chr4_-_136886187 1.482 ENSMUST00000046384.8
C1qb
complement component 1, q subcomponent, beta polypeptide
chr2_+_128126030 1.458 ENSMUST00000089634.5
ENSMUST00000019281.7
ENSMUST00000110341.2
ENSMUST00000103211.1
ENSMUST00000103210.1
Bcl2l11




BCL2-like 11 (apoptosis facilitator)




chr5_-_104021799 1.376 ENSMUST00000119025.1
Hsd17b11
hydroxysteroid (17-beta) dehydrogenase 11
chr3_+_138065052 1.212 ENSMUST00000163080.2
1110002E22Rik
RIKEN cDNA 1110002E22 gene
chr11_+_119393060 1.187 ENSMUST00000131035.2
ENSMUST00000093902.5
Rnf213

ring finger protein 213

chr2_+_71453276 1.118 ENSMUST00000037210.8
Metap1d
methionyl aminopeptidase type 1D (mitochondrial)
chr3_+_95526777 0.995 ENSMUST00000015667.2
ENSMUST00000116304.2
Ctss

cathepsin S

chr16_-_43664145 0.903 ENSMUST00000096065.4
Tigit
T cell immunoreceptor with Ig and ITIM domains
chr7_-_141010759 0.898 ENSMUST00000026565.6
Ifitm3
interferon induced transmembrane protein 3
chr16_-_26371828 0.886 ENSMUST00000023154.2
Cldn1
claudin 1
chr14_-_66124482 0.855 ENSMUST00000070515.1
Ephx2
epoxide hydrolase 2, cytoplasmic
chrX_+_150547375 0.822 ENSMUST00000066337.6
ENSMUST00000112715.1
Alas2

aminolevulinic acid synthase 2, erythroid

chr18_+_37484955 0.782 ENSMUST00000053856.4
Pcdhb17
protocadherin beta 17
chr16_+_35938972 0.765 ENSMUST00000023622.6
ENSMUST00000114877.1
Parp9

poly (ADP-ribose) polymerase family, member 9

chr10_-_41490335 0.756 ENSMUST00000019965.6
Smpd2
sphingomyelin phosphodiesterase 2, neutral
chr14_+_60732906 0.721 ENSMUST00000162945.1
Spata13
spermatogenesis associated 13
chr16_-_5255923 0.691 ENSMUST00000139584.1
ENSMUST00000064635.5
Fam86

family with sequence similarity 86

chr10_-_18234930 0.670 ENSMUST00000052648.8
ENSMUST00000080860.6
ENSMUST00000173243.1
Ccdc28a


coiled-coil domain containing 28A


chr9_+_64811313 0.612 ENSMUST00000038890.5
Dennd4a
DENN/MADD domain containing 4A
chr7_+_35586232 0.593 ENSMUST00000040844.9
Ankrd27
ankyrin repeat domain 27 (VPS9 domain)
chr7_+_4460687 0.586 ENSMUST00000167298.1
ENSMUST00000171445.1
Eps8l1

EPS8-like 1

chr2_-_127788854 0.573 ENSMUST00000028857.7
ENSMUST00000110357.1
Nphp1

nephronophthisis 1 (juvenile) homolog (human)

chr9_+_45042425 0.528 ENSMUST00000034600.4
Mpzl2
myelin protein zero-like 2
chr2_-_52335134 0.503 ENSMUST00000075301.3
Neb
nebulin
chr17_+_34564268 0.497 ENSMUST00000015612.7
Notch4
notch 4
chr8_+_128685654 0.492 ENSMUST00000090006.5
Itgb1
integrin beta 1 (fibronectin receptor beta)
chr13_-_81570640 0.477 ENSMUST00000109565.2
Gpr98
G protein-coupled receptor 98
chr15_-_50889691 0.455 ENSMUST00000165201.2
ENSMUST00000184458.1
Trps1

trichorhinophalangeal syndrome I (human)

chr10_+_86022189 0.449 ENSMUST00000120344.1
ENSMUST00000117597.1
Fbxo7

F-box protein 7

chr4_-_156200818 0.436 ENSMUST00000085425.4
Isg15
ISG15 ubiquitin-like modifier
chr4_-_89311021 0.425 ENSMUST00000097981.4
Cdkn2b
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
chr1_-_84935089 0.400 ENSMUST00000027422.5
Slc16a14
solute carrier family 16 (monocarboxylic acid transporters), member 14
chr12_-_79007276 0.391 ENSMUST00000056660.6
ENSMUST00000174721.1
Tmem229b

transmembrane protein 229B

chr10_-_78352323 0.387 ENSMUST00000001240.5
Agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr16_-_24393588 0.379 ENSMUST00000181640.1
1110054M08Rik
RIKEN cDNA 1110054M08 gene
chr13_-_23710714 0.360 ENSMUST00000091707.6
ENSMUST00000006787.7
ENSMUST00000091706.6
Hfe


hemochromatosis


chr1_-_93101825 0.345 ENSMUST00000112958.2
Kif1a
kinesin family member 1A
chr2_-_51934644 0.342 ENSMUST00000165313.1
Rbm43
RNA binding motif protein 43
chr7_-_16286744 0.319 ENSMUST00000150528.2
ENSMUST00000118976.2
ENSMUST00000146609.2
Ccdc9


coiled-coil domain containing 9


chr9_+_65346066 0.315 ENSMUST00000048184.2
Pdcd7
programmed cell death 7
chr7_-_65370908 0.310 ENSMUST00000032729.6
Tjp1
tight junction protein 1
chr1_-_93101854 0.307 ENSMUST00000171796.1
ENSMUST00000171556.1
Kif1a

kinesin family member 1A

chr10_+_126978690 0.299 ENSMUST00000105256.2
Ctdsp2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr10_-_78351711 0.284 ENSMUST00000105390.1
Agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr2_-_66410064 0.283 ENSMUST00000112366.1
Scn1a
sodium channel, voltage-gated, type I, alpha
chr4_-_4138817 0.283 ENSMUST00000133567.1
Penk
preproenkephalin
chr11_+_72689997 0.283 ENSMUST00000155998.1
Ankfy1
ankyrin repeat and FYVE domain containing 1
chrX_+_136707976 0.277 ENSMUST00000055104.5
Tceal1
transcription elongation factor A (SII)-like 1
chr5_+_28165690 0.271 ENSMUST00000036177.7
En2
engrailed 2
chr17_+_47410247 0.266 ENSMUST00000177586.1
Gm5814
predicted pseudogene 5814
chr12_-_4477138 0.252 ENSMUST00000085814.3
Ncoa1
nuclear receptor coactivator 1
chr10_-_78352053 0.249 ENSMUST00000105388.1
Agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr16_+_24393350 0.246 ENSMUST00000038053.6
Lpp
LIM domain containing preferred translocation partner in lipoma
chr10_-_78351690 0.235 ENSMUST00000166360.1
Agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr17_+_34203527 0.232 ENSMUST00000025197.5
Tap2
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
chr5_+_24393640 0.222 ENSMUST00000138168.1
ENSMUST00000115077.1
Abcb8

ATP-binding cassette, sub-family B (MDR/TAP), member 8

chr10_+_39612934 0.208 ENSMUST00000019987.6
Traf3ip2
TRAF3 interacting protein 2
chr3_+_89421619 0.205 ENSMUST00000094378.3
ENSMUST00000137793.1
Shc1

src homology 2 domain-containing transforming protein C1

chr8_+_90828820 0.199 ENSMUST00000109614.2
ENSMUST00000048665.6
Chd9

chromodomain helicase DNA binding protein 9

chr5_+_36796228 0.193 ENSMUST00000181278.1
Gm26605
predicted gene, 26605
chr18_+_7869707 0.188 ENSMUST00000166062.1
ENSMUST00000169010.1
Wac

WW domain containing adaptor with coiled-coil

chr8_+_105170668 0.185 ENSMUST00000109395.1
ENSMUST00000109394.1
ENSMUST00000052209.2
ENSMUST00000109392.1
Cbfb



core binding factor beta



chr11_-_101171302 0.184 ENSMUST00000164474.1
ENSMUST00000043397.7
Plekhh3

pleckstrin homology domain containing, family H (with MyTH4 domain) member 3

chr3_-_67375163 0.171 ENSMUST00000166353.1
Gm17402
predicted gene, 17402
chr2_-_9878580 0.168 ENSMUST00000102976.3
Gata3
GATA binding protein 3
chr14_+_120275669 0.166 ENSMUST00000088419.6
ENSMUST00000167459.1
Mbnl2

muscleblind-like 2

chr10_-_100589205 0.165 ENSMUST00000054471.8
4930430F08Rik
RIKEN cDNA 4930430F08 gene
chr13_-_113046357 0.157 ENSMUST00000022282.3
Gpx8
glutathione peroxidase 8 (putative)
chr15_+_102977032 0.147 ENSMUST00000001706.6
Hoxc9
homeobox C9
chr14_+_55578123 0.143 ENSMUST00000174484.1
Psme1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr13_-_18031616 0.128 ENSMUST00000099736.2
Vdac3-ps1
voltage-dependent anion channel 3, pseudogene 1
chr1_+_66468364 0.123 ENSMUST00000061620.9
Unc80
unc-80 homolog (C. elegans)
chr15_-_76243401 0.122 ENSMUST00000165738.1
ENSMUST00000075689.6
Parp10

poly (ADP-ribose) polymerase family, member 10

chr4_-_107178282 0.121 ENSMUST00000058585.7
Tceanc2
transcription elongation factor A (SII) N-terminal and central domain containing 2
chr2_+_147012996 0.113 ENSMUST00000028921.5
Xrn2
5'-3' exoribonuclease 2
chr17_-_30612613 0.111 ENSMUST00000167624.1
ENSMUST00000024823.6
Glo1

glyoxalase 1

chr12_-_110695860 0.103 ENSMUST00000149189.1
Hsp90aa1
heat shock protein 90, alpha (cytosolic), class A member 1
chr14_+_55578360 0.101 ENSMUST00000174259.1
ENSMUST00000174563.1
ENSMUST00000089619.6
ENSMUST00000172738.1
Psme1



proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)



chr17_+_8849974 0.096 ENSMUST00000115720.1
Pde10a
phosphodiesterase 10A
chr11_+_78245743 0.095 ENSMUST00000002133.8
Sdf2
stromal cell derived factor 2
chr1_-_57406443 0.091 ENSMUST00000160837.1
ENSMUST00000161780.1
Tyw5

tRNA-yW synthesizing protein 5

chr9_-_108428484 0.087 ENSMUST00000076592.2
Ccdc36
coiled-coil domain containing 36
chr10_-_111997204 0.083 ENSMUST00000074805.5
Glipr1
GLI pathogenesis-related 1 (glioma)
chr2_+_167062934 0.082 ENSMUST00000125674.1
1500012F01Rik
RIKEN cDNA 1500012F01 gene
chr6_+_71282280 0.075 ENSMUST00000080949.7
Krcc1
lysine-rich coiled-coil 1
chr11_+_43474276 0.074 ENSMUST00000173002.1
ENSMUST00000057679.3
C1qtnf2

C1q and tumor necrosis factor related protein 2

chr1_-_161876656 0.066 ENSMUST00000048377.5
Suco
SUN domain containing ossification factor
chr1_+_82724881 0.064 ENSMUST00000078332.6
Mff
mitochondrial fission factor
chrM_+_8600 0.064 ENSMUST00000082409.1
mt-Co3
mitochondrially encoded cytochrome c oxidase III
chr6_+_82041623 0.063 ENSMUST00000042974.8
Eva1a
eva-1 homolog A (C. elegans)
chr3_+_142496924 0.055 ENSMUST00000090127.2
Gbp5
guanylate binding protein 5
chr18_-_70530138 0.054 ENSMUST00000161542.1
ENSMUST00000159389.1
Poli

polymerase (DNA directed), iota

chr16_-_55838827 0.052 ENSMUST00000096026.2
ENSMUST00000036273.6
ENSMUST00000114457.1
Nfkbiz


nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta


chr1_+_155558112 0.052 ENSMUST00000080138.6
ENSMUST00000097529.3
ENSMUST00000035560.3
Acbd6


acyl-Coenzyme A binding domain containing 6


chr10_-_86022325 0.042 ENSMUST00000181665.1
A230060F14Rik
RIKEN cDNA A230060F14 gene
chr11_-_101551837 0.039 ENSMUST00000017290.4
Brca1
breast cancer 1
chr17_+_35424870 0.037 ENSMUST00000113879.3
H2-Q6
histocompatibility 2, Q region locus 6
chr1_+_74588347 0.036 ENSMUST00000113732.1
Bcs1l
BCS1-like (yeast)
chrX_+_112615301 0.032 ENSMUST00000122805.1
Zfp711
zinc finger protein 711
chr15_-_97705787 0.030 ENSMUST00000023104.5
Rpap3
RNA polymerase II associated protein 3
chr1_+_175632169 0.017 ENSMUST00000097458.3
Kmo
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr1_+_132008285 0.015 ENSMUST00000146432.1
Elk4
ELK4, member of ETS oncogene family
chr11_+_69966896 0.011 ENSMUST00000151515.1
Cldn7
claudin 7
chr9_+_58629102 0.001 ENSMUST00000176250.1
Nptn
neuroplastin
chr17_-_28915314 0.001 ENSMUST00000062357.4
4930539E08Rik
RIKEN cDNA 4930539E08 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0006553 lysine metabolic process(GO:0006553)
0.7 2.1 GO:1900041 intestinal D-glucose absorption(GO:0001951) negative regulation of interleukin-2 secretion(GO:1900041) terminal web assembly(GO:1902896)
0.5 1.6 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
0.4 1.8 GO:0003430 tolerance induction to self antigen(GO:0002513) growth plate cartilage chondrocyte growth(GO:0003430)
0.4 1.9 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.4 1.5 GO:0001907 killing by symbiont of host cells(GO:0001907) induction of programmed cell death(GO:0012502) disruption by symbiont of host cell(GO:0044004) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501) positive regulation of apoptotic process by virus(GO:0060139) apoptotic process involved in embryonic digit morphogenesis(GO:1902263) positive regulation of fibroblast apoptotic process(GO:2000271)
0.3 1.5 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.3 2.9 GO:0042447 hormone catabolic process(GO:0042447)
0.3 1.7 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.3 0.9 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) olefin metabolic process(GO:1900673)
0.2 1.8 GO:0009404 toxin metabolic process(GO:0009404)
0.2 0.5 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
0.1 1.9 GO:0048664 neuron fate determination(GO:0048664)
0.1 1.2 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 1.8 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 0.4 GO:0002578 negative regulation of antigen processing and presentation(GO:0002578)
0.1 0.9 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 0.8 GO:0060330 regulation of response to interferon-gamma(GO:0060330)
0.1 0.6 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.1 0.5 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.1 1.5 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 0.6 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.1 0.5 GO:0030832 regulation of actin filament length(GO:0030832)
0.1 0.6 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 1.0 GO:0010447 response to acidic pH(GO:0010447)
0.1 0.3 GO:0032439 endosome localization(GO:0032439)
0.1 0.8 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.1 0.2 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) cytosol to ER transport(GO:0046967) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.1 0.3 GO:2000987 positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
0.1 0.2 GO:0035799 ureter maturation(GO:0035799) cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) regulation of ureteric bud formation(GO:0072106) positive regulation of ureteric bud formation(GO:0072107) cell-cell signaling involved in metanephros development(GO:0072204) regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536)
0.1 0.4 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 0.9 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.8 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.3 GO:0000429 carbon catabolite regulation of transcription from RNA polymerase II promoter(GO:0000429) carbon catabolite activation of transcription from RNA polymerase II promoter(GO:0000436)
0.0 4.4 GO:0051592 response to calcium ion(GO:0051592)
0.0 0.1 GO:1902915 negative regulation of protein import into nucleus, translocation(GO:0033159) protein poly-ADP-ribosylation(GO:0070212) negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.0 1.4 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.2 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.0 0.1 GO:0031590 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.0 0.4 GO:0031670 cellular response to nutrient(GO:0031670)
0.0 0.3 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.3 GO:0070234 positive regulation of T cell apoptotic process(GO:0070234)
0.0 0.1 GO:0070589 cell wall mannoprotein biosynthetic process(GO:0000032) mannoprotein metabolic process(GO:0006056) mannoprotein biosynthetic process(GO:0006057) cell wall glycoprotein biosynthetic process(GO:0031506) cell wall biogenesis(GO:0042546) cell wall macromolecule metabolic process(GO:0044036) cell wall macromolecule biosynthetic process(GO:0044038) chain elongation of O-linked mannose residue(GO:0044845) cellular component macromolecule biosynthetic process(GO:0070589) cell wall organization or biogenesis(GO:0071554)
0.0 0.3 GO:1990403 embryonic brain development(GO:1990403)
0.0 0.5 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.1 GO:0045583 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.0 0.7 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.1 GO:0032621 interleukin-18 production(GO:0032621) positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 0.8 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.0 GO:2000620 programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) positive regulation of histone H4-K16 acetylation(GO:2000620)
0.0 0.2 GO:0048305 immunoglobulin secretion(GO:0048305)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.3 1.5 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.2 0.5 GO:0034679 integrin alpha2-beta1 complex(GO:0034666) integrin alpha3-beta1 complex(GO:0034667) integrin alpha9-beta1 complex(GO:0034679)
0.2 1.6 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 1.0 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.6 GO:0097422 tubular endosome(GO:0097422)
0.1 0.4 GO:1990357 terminal web(GO:1990357)
0.1 0.3 GO:0032280 symmetric synapse(GO:0032280)
0.1 0.2 GO:0008537 proteasome activator complex(GO:0008537)
0.0 2.9 GO:0005811 lipid particle(GO:0005811)
0.0 0.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.3 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 1.8 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.2 GO:0042825 TAP complex(GO:0042825)
0.0 1.9 GO:0014704 intercalated disc(GO:0014704)
0.0 2.5 GO:0005901 caveola(GO:0005901)
0.0 0.1 GO:0031502 dolichyl-phosphate-mannose-protein mannosyltransferase complex(GO:0031502)
0.0 1.6 GO:0005581 collagen trimer(GO:0005581)
0.0 3.9 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.5 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.1 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.0 0.6 GO:0097546 ciliary base(GO:0097546)
0.0 0.9 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 1.3 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.9 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 1.7 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.7 GO:0005871 kinesin complex(GO:0005871)
0.0 0.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.2 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.6 1.8 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.5 1.5 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.5 1.9 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.4 1.8 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.4 2.9 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.2 2.1 GO:0044548 S100 protein binding(GO:0044548)
0.1 0.9 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.1 2.9 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.5 GO:0098634 protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 0.8 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 2.0 GO:0071837 HMG box domain binding(GO:0071837)
0.1 0.2 GO:0023029 peptide antigen-transporting ATPase activity(GO:0015433) MHC class Ib protein binding(GO:0023029) tapasin binding(GO:0046980)
0.1 1.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 1.2 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 0.8 GO:0016594 glycine binding(GO:0016594)
0.1 0.2 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.3 GO:0033142 progesterone receptor binding(GO:0033142)
0.0 0.3 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.4 GO:0039706 co-receptor binding(GO:0039706)
0.0 1.0 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.1 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.0 0.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 1.5 GO:0045502 dynein binding(GO:0045502)
0.0 0.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.4 GO:0031386 protein tag(GO:0031386)
0.0 1.6 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0002135 CTP binding(GO:0002135)
0.0 0.5 GO:0005112 Notch binding(GO:0005112)
0.0 0.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.3 GO:0031402 sodium ion binding(GO:0031402)
0.0 1.7 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.1 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.5 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 1.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.7 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.4 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)