Motif ID: Ptf1a

Z-value: 0.514


Transcription factors associated with Ptf1a:

Gene SymbolEntrez IDGene Name
Ptf1a ENSMUSG00000026735.2 Ptf1a



Activity profile for motif Ptf1a.

activity profile for motif Ptf1a


Sorted Z-values histogram for motif Ptf1a

Sorted Z-values for motif Ptf1a



Network of associatons between targets according to the STRING database.



First level regulatory network of Ptf1a

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_79386943 4.840 ENSMUST00000053718.8
ENSMUST00000179243.1
 Rlbp1

retinaldehyde binding protein 1

chr11_+_78324200 1.957 ENSMUST00000102478.3
 Aldoc
aldolase C, fructose-bisphosphate
chr18_+_24709436 1.929 ENSMUST00000037097.7
 Fhod3
formin homology 2 domain containing 3
chr16_+_91269759 1.874 ENSMUST00000056882.5
 Olig1
oligodendrocyte transcription factor 1
chr14_-_70207637 1.865 ENSMUST00000022682.5
 Sorbs3
sorbin and SH3 domain containing 3
chr4_-_64046925 1.723 ENSMUST00000107377.3
 Tnc
tenascin C
chr5_-_99252839 1.139 ENSMUST00000168092.1
ENSMUST00000031276.8
 Rasgef1b

RasGEF domain family, member 1B

chr19_+_7056731 1.133 ENSMUST00000040261.5
 Macrod1
MACRO domain containing 1
chr4_-_88438900 1.128 ENSMUST00000132493.1
ENSMUST00000030221.2
ENSMUST00000151280.1
 Ptplad2


protein tyrosine phosphatase-like A domain containing 2


chr6_-_5256226 0.899 ENSMUST00000125686.1
ENSMUST00000031773.2
 Pon3

paraoxonase 3

chrX_+_166238923 0.781 ENSMUST00000060210.7
ENSMUST00000112233.1
 Gpm6b

glycoprotein m6b

chr9_-_112187898 0.780 ENSMUST00000178410.1
ENSMUST00000172380.3
 Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr5_+_64970069 0.777 ENSMUST00000031080.8
 Fam114a1
family with sequence similarity 114, member A1
chr7_-_144582392 0.645 ENSMUST00000033394.7
 Fadd
Fas (TNFRSF6)-associated via death domain
chr11_-_118355496 0.603 ENSMUST00000017610.3
 Timp2
tissue inhibitor of metalloproteinase 2
chr11_-_109611417 0.587 ENSMUST00000103060.3
ENSMUST00000047186.3
ENSMUST00000106689.1
 Wipi1


WD repeat domain, phosphoinositide interacting 1


chr18_+_37477768 0.561 ENSMUST00000051442.5
 Pcdhb16
protocadherin beta 16
chr2_-_30415302 0.513 ENSMUST00000132981.2
ENSMUST00000129494.1
 Crat

carnitine acetyltransferase

chr2_-_91950386 0.498 ENSMUST00000111303.1
 Dgkz
diacylglycerol kinase zeta
chr8_-_105295934 0.490 ENSMUST00000057855.3
 Exoc3l
exocyst complex component 3-like
chr9_+_106477269 0.486 ENSMUST00000047721.8
 Rrp9
RRP9, small subunit (SSU) processome component, homolog (yeast)
chr10_-_126901315 0.485 ENSMUST00000026504.5
ENSMUST00000168520.1
 Xrcc6bp1

XRCC6 binding protein 1

chr9_+_123021315 0.479 ENSMUST00000084733.5
 Tmem42
transmembrane protein 42
chr2_-_118703963 0.476 ENSMUST00000104937.1
 Ankrd63
ankyrin repeat domain 63
chr4_+_152096719 0.471 ENSMUST00000105661.3
ENSMUST00000084115.3
 Plekhg5

pleckstrin homology domain containing, family G (with RhoGef domain) member 5

chr15_+_80097866 0.453 ENSMUST00000143928.1
 Syngr1
synaptogyrin 1
chr2_+_31470207 0.442 ENSMUST00000102840.4
 Ass1
argininosuccinate synthetase 1
chr10_+_86022189 0.425 ENSMUST00000120344.1
ENSMUST00000117597.1
 Fbxo7

F-box protein 7

chr11_+_49247462 0.408 ENSMUST00000109194.1
 Mgat1
mannoside acetylglucosaminyltransferase 1
chr17_+_7925990 0.354 ENSMUST00000036370.7
 Tagap
T cell activation Rho GTPase activating protein
chr2_+_164948219 0.338 ENSMUST00000017881.2
 Mmp9
matrix metallopeptidase 9
chr7_-_99182681 0.336 ENSMUST00000033001.4
 Dgat2
diacylglycerol O-acyltransferase 2
chr11_-_96916448 0.333 ENSMUST00000103152.4
 Cdk5rap3
CDK5 regulatory subunit associated protein 3
chr7_-_79842287 0.324 ENSMUST00000049004.6
 Anpep
alanyl (membrane) aminopeptidase
chr11_-_96916366 0.310 ENSMUST00000144731.1
ENSMUST00000127048.1
 Cdk5rap3

CDK5 regulatory subunit associated protein 3

chr2_-_175131864 0.308 ENSMUST00000108929.2
 Gm14399
predicted gene 14399
chr11_-_100441006 0.306 ENSMUST00000092689.2
 Nt5c3b
5'-nucleotidase, cytosolic IIIB
chr8_-_13890233 0.304 ENSMUST00000033839.7
 Coprs
coordinator of PRMT5, differentiation stimulator
chr9_-_108597558 0.300 ENSMUST00000006853.5
 P4htm
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr11_-_103344651 0.292 ENSMUST00000041385.7
 Arhgap27
Rho GTPase activating protein 27
chr1_+_92910805 0.282 ENSMUST00000179711.1
 Rnpepl1
arginyl aminopeptidase (aminopeptidase B)-like 1
chr10_+_60346851 0.271 ENSMUST00000020301.7
ENSMUST00000105460.1
ENSMUST00000170507.1
 4632428N05Rik


RIKEN cDNA 4632428N05 gene


chr10_+_42678890 0.268 ENSMUST00000040718.5
 Ostm1
osteopetrosis associated transmembrane protein 1
chr11_-_100441058 0.251 ENSMUST00000107399.2
ENSMUST00000092688.5
 Nt5c3b

5'-nucleotidase, cytosolic IIIB

chr11_-_96916407 0.249 ENSMUST00000130774.1
 Cdk5rap3
CDK5 regulatory subunit associated protein 3
chr1_-_88008520 0.234 ENSMUST00000040783.4
 Usp40
ubiquitin specific peptidase 40
chr11_-_100440928 0.222 ENSMUST00000107397.1
 Nt5c3b
5'-nucleotidase, cytosolic IIIB
chr11_-_6444352 0.221 ENSMUST00000093346.5
ENSMUST00000109737.2
 H2afv

H2A histone family, member V

chr10_-_75932468 0.219 ENSMUST00000120281.1
ENSMUST00000000924.6
 Mmp11

matrix metallopeptidase 11

chr10_-_95417099 0.212 ENSMUST00000135822.1
 Socs2
suppressor of cytokine signaling 2
chr1_+_92910758 0.210 ENSMUST00000027487.8
 Rnpepl1
arginyl aminopeptidase (aminopeptidase B)-like 1
chr18_+_32377176 0.203 ENSMUST00000091967.5
ENSMUST00000025239.7
 Bin1

bridging integrator 1

chr11_+_48800357 0.189 ENSMUST00000020640.7
 Gnb2l1
guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1
chr14_-_55944536 0.183 ENSMUST00000022834.6
 Cma1
chymase 1, mast cell
chr14_+_75845093 0.180 ENSMUST00000110894.2
 Tpt1
tumor protein, translationally-controlled 1
chr19_+_9982694 0.167 ENSMUST00000025563.6
 Fth1
ferritin heavy chain 1
chr5_+_34525797 0.165 ENSMUST00000125817.1
ENSMUST00000067638.7
 Sh3bp2

SH3-domain binding protein 2

chr7_+_46396439 0.158 ENSMUST00000025202.6
 Kcnc1
potassium voltage gated channel, Shaw-related subfamily, member 1
chr2_+_25500750 0.155 ENSMUST00000015239.3
 Fbxw5
F-box and WD-40 domain protein 5
chr5_-_31048014 0.154 ENSMUST00000137223.1
 Slc5a6
solute carrier family 5 (sodium-dependent vitamin transporter), member 6
chr7_-_4532419 0.154 ENSMUST00000094897.4
 Dnaaf3
dynein, axonemal assembly factor 3
chr19_-_7241216 0.140 ENSMUST00000025675.9
 Naa40
N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)
chr6_+_83078339 0.133 ENSMUST00000165164.2
ENSMUST00000092614.2
 Pcgf1

polycomb group ring finger 1

chr8_+_94857450 0.128 ENSMUST00000109521.3
 Polr2c
polymerase (RNA) II (DNA directed) polypeptide C
chr11_+_78465697 0.126 ENSMUST00000001126.3
 Slc46a1
solute carrier family 46, member 1
chr4_+_155839675 0.119 ENSMUST00000141883.1
 Mxra8
matrix-remodelling associated 8
chr9_-_108305941 0.112 ENSMUST00000044725.7
 Tcta
T cell leukemia translocation altered gene
chrX_+_101383726 0.105 ENSMUST00000119190.1
 Gjb1
gap junction protein, beta 1
chr14_+_53324632 0.099 ENSMUST00000178100.1
 Trav7n-6
T cell receptor alpha variable 7N-6
chr6_+_83078606 0.096 ENSMUST00000177177.1
ENSMUST00000176089.1
 Pcgf1

polycomb group ring finger 1

chr11_-_93965957 0.096 ENSMUST00000021220.3
 Nme1
NME/NM23 nucleoside diphosphate kinase 1
chr1_+_36471590 0.094 ENSMUST00000153128.1
 Cnnm4
cyclin M4
chr11_+_19924403 0.087 ENSMUST00000093298.5
 Spred2
sprouty-related, EVH1 domain containing 2
chr5_+_134099704 0.085 ENSMUST00000016088.8
 Gatsl2
GATS protein-like 2
chr9_-_112234956 0.083 ENSMUST00000162097.1
ENSMUST00000159055.1
 Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr3_-_108445183 0.067 ENSMUST00000090553.5
ENSMUST00000153499.1
 Sars

seryl-aminoacyl-tRNA synthetase

chr16_+_96145391 0.055 ENSMUST00000023913.8
ENSMUST00000135448.1
 Wrb

tryptophan rich basic protein

chr11_+_50131342 0.048 ENSMUST00000093138.6
ENSMUST00000101270.4
 Tbc1d9b

TBC1 domain family, member 9B

chr7_-_127725616 0.047 ENSMUST00000076091.2
 Ctf2
cardiotrophin 2
chr11_+_82911253 0.044 ENSMUST00000164945.1
ENSMUST00000018989.7
 Unc45b

unc-45 homolog B (C. elegans)

chr11_-_90390895 0.036 ENSMUST00000004051.7
 Hlf
hepatic leukemia factor
chr10_-_77089428 0.027 ENSMUST00000156009.1
 Col18a1
collagen, type XVIII, alpha 1
chrX_-_164076482 0.008 ENSMUST00000134272.1
 Siah1b
seven in absentia 1B
chr4_+_115088708 0.000 ENSMUST00000171877.1
ENSMUST00000177647.1
ENSMUST00000106548.2
ENSMUST00000030488.2
 Pdzk1ip1



PDZK1 interacting protein 1




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.3 1.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.2 0.6 GO:2000409 positive regulation of T cell extravasation(GO:2000409)
0.2 1.9 GO:0051639 actin filament network formation(GO:0051639)
0.2 2.0 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.9 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.1 0.6 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.8 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 0.4 GO:0010046 arginine biosynthetic process(GO:0006526) response to mycotoxin(GO:0010046)
0.1 0.4 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.1 0.9 GO:0071569 protein ufmylation(GO:0071569)
0.1 0.5 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.1 0.3 GO:0031915 positive regulation of synaptic plasticity(GO:0031915) positive regulation of receptor binding(GO:1900122)
0.1 0.3 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.1 0.6 GO:0048199 vesicle targeting, to, from or within Golgi(GO:0048199)
0.1 0.3 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.0 0.2 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.0 0.5 GO:0051601 exocyst localization(GO:0051601)
0.0 0.2 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.0 1.9 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.1 GO:0015886 heme transport(GO:0015886)
0.0 0.6 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.3 GO:0035814 negative regulation of renal sodium excretion(GO:0035814)
0.0 2.4 GO:0007601 visual perception(GO:0007601)
0.0 0.2 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
0.0 0.5 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.0 1.9 GO:0048663 neuron fate commitment(GO:0048663)
0.0 0.5 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.7 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.5 GO:0035767 endothelial cell chemotaxis(GO:0035767)
0.0 0.2 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.2 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.1 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.0 0.1 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.2 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0031983 vesicle lumen(GO:0031983)
0.1 1.7 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.6 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.1 1.9 GO:0005865 striated muscle thin filament(GO:0005865)
0.1 0.5 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.6 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.4 GO:0070852 cell body fiber(GO:0070852)
0.0 0.5 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0045298 tubulin complex(GO:0045298)
0.0 0.6 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.2 GO:0043196 varicosity(GO:0043196)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.8 GO:0019841 retinol binding(GO:0019841)
0.3 2.0 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.3 1.7 GO:0045545 syndecan binding(GO:0045545)
0.2 0.9 GO:0004064 arylesterase activity(GO:0004064)
0.2 0.6 GO:0035877 death effector domain binding(GO:0035877) caspase binding(GO:0089720)
0.1 0.5 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)
0.1 0.3 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.1 1.9 GO:0017166 vinculin binding(GO:0017166)
0.1 0.4 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 0.5 GO:0034511 U3 snoRNA binding(GO:0034511)
0.1 1.1 GO:0070636 single-strand selective uracil DNA N-glycosylase activity(GO:0017065) nicotinamide riboside hydrolase activity(GO:0070635) nicotinic acid riboside hydrolase activity(GO:0070636) deoxyribonucleoside 5'-monophosphate N-glycosidase activity(GO:0070694)
0.1 0.5 GO:0001727 lipid kinase activity(GO:0001727)
0.1 0.9 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.4 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.8 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.8 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.2 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.2 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.6 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 0.2 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.0 0.3 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.3 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.1 GO:0001055 RNA polymerase II activity(GO:0001055)