Motif ID: Tbx19

Z-value: 0.748


Transcription factors associated with Tbx19:

Gene SymbolEntrez IDGene Name
Tbx19 ENSMUSG00000026572.5 Tbx19



Activity profile for motif Tbx19.

activity profile for motif Tbx19


Sorted Z-values histogram for motif Tbx19

Sorted Z-values for motif Tbx19



Network of associatons between targets according to the STRING database.



First level regulatory network of Tbx19

PNG image of the network

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Top targets:


Showing 1 to 20 of 102 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_113758638 3.966 ENSMUST00000099575.3
 Grem1
gremlin 1
chr18_-_82406777 3.477 ENSMUST00000065224.6
 Galr1
galanin receptor 1
chr7_+_130936172 3.230 ENSMUST00000006367.7
 Htra1
HtrA serine peptidase 1
chr2_+_179442427 3.087 ENSMUST00000000314.6
 Cdh4
cadherin 4
chr7_+_48959089 2.901 ENSMUST00000183659.1
 Nav2
neuron navigator 2
chr3_+_94693556 2.074 ENSMUST00000090848.3
ENSMUST00000173981.1
ENSMUST00000173849.1
ENSMUST00000174223.1
 Selenbp2



selenium binding protein 2



chr6_+_90465287 1.798 ENSMUST00000113530.1
 Klf15
Kruppel-like factor 15
chr14_-_66124482 1.574 ENSMUST00000070515.1
 Ephx2
epoxide hydrolase 2, cytoplasmic
chr19_+_5474681 1.394 ENSMUST00000165485.1
ENSMUST00000166253.1
ENSMUST00000167371.1
ENSMUST00000167855.1
ENSMUST00000070118.7
 Efemp2




epidermal growth factor-containing fibulin-like extracellular matrix protein 2




chr5_-_92278155 1.233 ENSMUST00000159345.1
ENSMUST00000113102.3
 Naaa

N-acylethanolamine acid amidase

chr6_+_17749170 1.134 ENSMUST00000053148.7
ENSMUST00000115417.3
 St7

suppression of tumorigenicity 7

chr5_-_115484297 1.103 ENSMUST00000112067.1
 Sirt4
sirtuin 4
chr6_+_86195214 1.039 ENSMUST00000032066.9
 Tgfa
transforming growth factor alpha
chr2_+_175010241 1.032 ENSMUST00000109069.1
ENSMUST00000109070.2
 Gm14444

predicted gene 14444

chr11_-_60046477 1.031 ENSMUST00000000310.7
ENSMUST00000102693.2
ENSMUST00000148512.1
 Pemt


phosphatidylethanolamine N-methyltransferase


chr17_+_6978860 1.026 ENSMUST00000089119.5
ENSMUST00000179728.1
 Rnaset2b

ribonuclease T2B

chr18_+_37484955 1.009 ENSMUST00000053856.4
 Pcdhb17
protocadherin beta 17
chr13_-_74376566 0.897 ENSMUST00000091481.2
 Zfp72
zinc finger protein 72
chr7_-_140955960 0.876 ENSMUST00000081649.8
 Ifitm2
interferon induced transmembrane protein 2
chr2_-_175067763 0.813 ENSMUST00000072895.3
ENSMUST00000109066.1
 Gm14393

predicted gene 14393


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 42 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.3 4.0 GO:1901228 regulation of osteoclast proliferation(GO:0090289) negative regulation of bone mineralization involved in bone maturation(GO:1900158) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
1.1 3.3 GO:0051464 positive regulation of cortisol secretion(GO:0051464)
0.5 3.2 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.1 3.1 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.7 2.9 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.1 1.8 GO:0072010 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.5 1.6 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) olefin metabolic process(GO:1900673)
0.3 1.4 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.2 1.1 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.1 1.0 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 0.9 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.2 0.8 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.1 0.8 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.1 0.8 GO:0097460 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import into cell(GO:0097460)
0.1 0.7 GO:0098734 protein depalmitoylation(GO:0002084) positive regulation of pinocytosis(GO:0048549) macromolecule depalmitoylation(GO:0098734)
0.1 0.7 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.0 0.7 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.7 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0 0.7 GO:0072661 protein targeting to plasma membrane(GO:0072661)
0.0 0.6 GO:0042640 anagen(GO:0042640)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.9 GO:0031012 extracellular matrix(GO:0031012)
0.0 3.9 GO:0009986 cell surface(GO:0009986)
0.2 2.9 GO:0005614 interstitial matrix(GO:0005614)
0.0 1.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.0 GO:0031526 brush border membrane(GO:0031526)
0.0 0.9 GO:0070469 respiratory chain(GO:0070469)
0.1 0.8 GO:0097433 dense body(GO:0097433)
0.1 0.8 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 0.7 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.7 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.7 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.7 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.6 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 0.5 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.4 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.4 GO:0015030 Cajal body(GO:0015030)
0.1 0.3 GO:0000802 transverse filament(GO:0000802)
0.1 0.3 GO:0097361 CIA complex(GO:0097361)
0.1 0.3 GO:0033093 multivesicular body membrane(GO:0032585) Weibel-Palade body(GO:0033093)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 4.0 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
1.1 3.3 GO:0004966 galanin receptor activity(GO:0004966)
0.2 3.2 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 2.9 GO:0008201 heparin binding(GO:0008201)
0.1 2.1 GO:0008430 selenium binding(GO:0008430)
0.3 1.6 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.1 1.2 GO:0043747 protein-N-terminal asparagine amidohydrolase activity(GO:0008418) UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity(GO:0008759) iprodione amidohydrolase activity(GO:0018748) (3,5-dichlorophenylurea)acetate amidohydrolase activity(GO:0018749) 4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity(GO:0034571) didemethylisoproturon amidohydrolase activity(GO:0034573) N-isopropylacetanilide amidohydrolase activity(GO:0034576) N-cyclohexylformamide amidohydrolase activity(GO:0034781) isonicotinic acid hydrazide hydrolase activity(GO:0034876) cis-aconitamide amidase activity(GO:0034882) gamma-N-formylaminovinylacetate hydrolase activity(GO:0034885) N2-acetyl-L-lysine deacetylase activity(GO:0043747) O-succinylbenzoate synthase activity(GO:0043748) indoleacetamide hydrolase activity(GO:0043864) N-acetylcitrulline deacetylase activity(GO:0043909) N-acetylgalactosamine-6-phosphate deacetylase activity(GO:0047419) diacetylchitobiose deacetylase activity(GO:0052773) chitooligosaccharide deacetylase activity(GO:0052790)
0.2 1.1 GO:0018121 imidazoleglycerol-phosphate synthase activity(GO:0000107) NAD(P)-cysteine ADP-ribosyltransferase activity(GO:0018071) NAD(P)-asparagine ADP-ribosyltransferase activity(GO:0018121) NAD(P)-serine ADP-ribosyltransferase activity(GO:0018127) 7-cyano-7-deazaguanine tRNA-ribosyltransferase activity(GO:0043867) purine deoxyribosyltransferase activity(GO:0044102)
0.1 1.0 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 1.0 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.9 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.8 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.0 0.8 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.1 0.7 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.1 0.7 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.5 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.5 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.4 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.4 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.4 GO:0008758 thiamine-pyrophosphatase activity(GO:0004787) UDP-2,3-diacylglucosamine hydrolase activity(GO:0008758) dATP pyrophosphohydrolase activity(GO:0008828) dihydroneopterin monophosphate phosphatase activity(GO:0019176) dihydroneopterin triphosphate pyrophosphohydrolase activity(GO:0019177) dTTP diphosphatase activity(GO:0036218) phosphocholine hydrolase activity(GO:0044606)