Motif ID: Hoxd10

Z-value: 0.424


Transcription factors associated with Hoxd10:

Gene SymbolEntrez IDGene Name
Hoxd10 ENSMUSG00000050368.3 Hoxd10



Activity profile for motif Hoxd10.

activity profile for motif Hoxd10


Sorted Z-values histogram for motif Hoxd10

Sorted Z-values for motif Hoxd10



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxd10

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_84773381 2.016 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr3_-_80802789 1.610 ENSMUST00000107745.1
ENSMUST00000075316.4
 Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr9_+_27790947 1.589 ENSMUST00000115243.2
 Opcml
opioid binding protein/cell adhesion molecule-like
chr3_+_86084434 1.436 ENSMUST00000107664.2
 Sh3d19
SH3 domain protein D19
chr7_+_96210107 1.132 ENSMUST00000138760.1
 Tenm4
teneurin transmembrane protein 4
chr15_+_25773985 0.987 ENSMUST00000125667.1
 Myo10
myosin X
chrX_+_66653003 0.968 ENSMUST00000036043.4
 Slitrk2
SLIT and NTRK-like family, member 2
chr17_-_78684262 0.782 ENSMUST00000145480.1
 Strn
striatin, calmodulin binding protein
chr17_+_78508063 0.779 ENSMUST00000024880.9
 Vit
vitrin
chr1_-_45503282 0.711 ENSMUST00000086430.4
 Col5a2
collagen, type V, alpha 2
chr9_-_90255927 0.689 ENSMUST00000144646.1
 Tbc1d2b
TBC1 domain family, member 2B
chr15_+_9140527 0.665 ENSMUST00000090380.4
 Lmbrd2
LMBR1 domain containing 2
chr6_-_28397999 0.641 ENSMUST00000035930.4
 Zfp800
zinc finger protein 800
chr10_+_69534039 0.576 ENSMUST00000182557.1
 Ank3
ankyrin 3, epithelial
chr2_+_106693185 0.506 ENSMUST00000111063.1
 Mpped2
metallophosphoesterase domain containing 2
chr15_+_57912199 0.459 ENSMUST00000022992.6
 Tbc1d31
TBC1 domain family, member 31
chr9_+_95857597 0.413 ENSMUST00000034980.7
 Atr
ataxia telangiectasia and Rad3 related
chr6_+_33249085 0.343 ENSMUST00000052266.8
ENSMUST00000090381.4
ENSMUST00000115080.1
 Exoc4


exocyst complex component 4


chr1_-_152625212 0.337 ENSMUST00000027760.7
 Rgl1
ral guanine nucleotide dissociation stimulator,-like 1
chr13_+_40917626 0.331 ENSMUST00000067778.6
 Gcnt2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr1_+_180111339 0.303 ENSMUST00000145181.1
 Cdc42bpa
CDC42 binding protein kinase alpha
chr7_-_73541738 0.262 ENSMUST00000169922.2
 Chd2
chromodomain helicase DNA binding protein 2
chr14_+_79515618 0.246 ENSMUST00000110835.1
 Elf1
E74-like factor 1
chr9_+_92542223 0.203 ENSMUST00000070522.7
ENSMUST00000160359.1
 Plod2

procollagen lysine, 2-oxoglutarate 5-dioxygenase 2

chrX_-_74246534 0.202 ENSMUST00000101454.2
ENSMUST00000033699.6
 Flna

filamin, alpha

chr16_-_16560046 0.193 ENSMUST00000172181.2
 Fgd4
FYVE, RhoGEF and PH domain containing 4
chr17_-_46327949 0.172 ENSMUST00000047970.7
 Abcc10
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
chr7_+_30095150 0.151 ENSMUST00000130526.1
ENSMUST00000108200.1
 Zfp260

zinc finger protein 260

chr9_-_45828618 0.108 ENSMUST00000117194.1
 Cep164
centrosomal protein 164
chrX_+_7762652 0.098 ENSMUST00000077680.3
ENSMUST00000079542.6
ENSMUST00000115679.1
ENSMUST00000137467.1
 Tfe3



transcription factor E3



chr4_+_100478806 0.093 ENSMUST00000133493.2
ENSMUST00000092730.3
ENSMUST00000106979.3
 Ube2u


ubiquitin-conjugating enzyme E2U (putative)


chrX_-_70365052 0.081 ENSMUST00000101509.2
 Ids
iduronate 2-sulfatase
chr5_-_122697603 0.080 ENSMUST00000071235.4
 Gm10064
predicted gene 10064
chr18_-_6490808 0.067 ENSMUST00000028100.6
ENSMUST00000050542.5
 Epc1

enhancer of polycomb homolog 1 (Drosophila)

chr19_+_37436707 0.064 ENSMUST00000128184.1
 Hhex
hematopoietically expressed homeobox
chr10_+_21295979 0.051 ENSMUST00000020153.8
ENSMUST00000092674.6
 Hbs1l

Hbs1-like (S. cerevisiae)

chr2_+_21367532 0.024 ENSMUST00000055946.7
 Gpr158
G protein-coupled receptor 158

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0032289 central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912)
0.2 0.7 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 2.0 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 0.4 GO:1904884 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.1 1.6 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 0.3 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 1.4 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.6 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.3 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.2 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.2 GO:0030035 microspike assembly(GO:0030035)
0.0 0.3 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.1 GO:0061010 gall bladder development(GO:0061010)
0.0 1.0 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.2 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.3 GO:0007097 nuclear migration(GO:0007097)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0005588 collagen type V trimer(GO:0005588)
0.1 1.6 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.8 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0031523 Myb complex(GO:0031523)
0.0 0.3 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.6 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0033503 HULC complex(GO:0033503)
0.0 0.4 GO:0001741 XY body(GO:0001741)
0.0 1.0 GO:0016459 myosin complex(GO:0016459)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 0.3 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 0.4 GO:0032405 MutLalpha complex binding(GO:0032405) MutSalpha complex binding(GO:0032407)
0.1 1.4 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.3 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.2 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.1 0.2 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.8 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 1.6 GO:0030507 spectrin binding(GO:0030507)
0.0 0.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.3 GO:0017160 Ral GTPase binding(GO:0017160)