Motif ID: Hoxc9

Z-value: 1.016


Transcription factors associated with Hoxc9:

Gene SymbolEntrez IDGene Name
Hoxc9 ENSMUSG00000036139.6 Hoxc9

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hoxc9mm10_v2_chr15_+_102977032_1029770320.501.6e-02Click!


Activity profile for motif Hoxc9.

activity profile for motif Hoxc9


Sorted Z-values histogram for motif Hoxc9

Sorted Z-values for motif Hoxc9



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxc9

PNG image of the network

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Top targets:


Showing 1 to 20 of 68 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_+_80000292 4.609 ENSMUST00000088735.3
 Olfm4
olfactomedin 4
chr4_+_144893127 4.534 ENSMUST00000142808.1
 Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr1_+_58210397 4.399 ENSMUST00000040442.5
 Aox4
aldehyde oxidase 4
chr13_+_94083490 4.381 ENSMUST00000156071.1
 Lhfpl2
lipoma HMGIC fusion partner-like 2
chr16_-_37384915 4.012 ENSMUST00000114787.1
ENSMUST00000114782.1
ENSMUST00000023526.2
ENSMUST00000114775.1
 Stxbp5l



syntaxin binding protein 5-like



chr2_+_70474923 3.476 ENSMUST00000100043.2
 Sp5
trans-acting transcription factor 5
chr2_+_4300462 3.196 ENSMUST00000175669.1
 Frmd4a
FERM domain containing 4A
chr16_-_37384940 2.985 ENSMUST00000114781.1
ENSMUST00000114780.1
 Stxbp5l

syntaxin binding protein 5-like

chr4_+_107830958 2.951 ENSMUST00000106731.2
 Lrp8
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr1_-_45503282 2.831 ENSMUST00000086430.4
 Col5a2
collagen, type V, alpha 2
chr2_-_26516620 2.393 ENSMUST00000132820.1
 Notch1
notch 1
chr8_-_120228221 2.318 ENSMUST00000183235.1
 A330074K22Rik
RIKEN cDNA A330074K22 gene
chrX_-_105928547 1.756 ENSMUST00000101305.2
 Atrx
alpha thalassemia/mental retardation syndrome X-linked homolog (human)
chr3_+_66985680 1.737 ENSMUST00000065047.6
 Rsrc1
arginine/serine-rich coiled-coil 1
chr9_+_35423582 1.614 ENSMUST00000154652.1
 Cdon
cell adhesion molecule-related/down-regulated by oncogenes
chrX_-_141474034 1.612 ENSMUST00000101205.2
 Col4a6
collagen, type IV, alpha 6
chr17_-_57000018 1.606 ENSMUST00000002740.2
 Pspn
persephin
chr11_+_3330401 1.494 ENSMUST00000045153.4
 Pik3ip1
phosphoinositide-3-kinase interacting protein 1
chr17_-_49564262 1.486 ENSMUST00000057610.6
 Daam2
dishevelled associated activator of morphogenesis 2
chr2_+_91256144 1.401 ENSMUST00000154959.1
ENSMUST00000059566.4
 Pacsin3

protein kinase C and casein kinase substrate in neurons 3


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 7.0 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.1 4.6 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.4 4.5 GO:0042572 retinol metabolic process(GO:0042572)
1.5 4.4 GO:0046110 xanthine metabolic process(GO:0046110)
0.1 3.5 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.7 3.3 GO:0060690 epithelial cell differentiation involved in salivary gland development(GO:0060690)
0.1 3.2 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.3 3.0 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.9 2.8 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.8 2.4 GO:0003219 atrioventricular node development(GO:0003162) cardiac right ventricle formation(GO:0003219)
0.1 2.3 GO:0046677 response to antibiotic(GO:0046677)
0.1 1.9 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.4 1.8 GO:0097393 post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582)
0.2 1.6 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.1 1.6 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 1.6 GO:0001658 branching involved in ureteric bud morphogenesis(GO:0001658)
0.5 1.5 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 1.0 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 0.7 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.1 0.6 GO:0061042 vascular wound healing(GO:0061042)

Gene overrepresentation in cellular_component category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 7.0 GO:0031201 SNARE complex(GO:0031201)
0.3 4.6 GO:0042581 specific granule(GO:0042581)
0.3 3.3 GO:0005915 zonula adherens(GO:0005915)
0.0 3.2 GO:0005923 bicellular tight junction(GO:0005923)
0.9 2.8 GO:0005588 collagen type V trimer(GO:0005588)
0.5 2.4 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 2.3 GO:0016607 nuclear speck(GO:0016607)
0.0 2.2 GO:0005875 microtubule associated complex(GO:0005875)
0.4 1.8 GO:1990421 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
0.3 1.6 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 0.7 GO:0005882 intermediate filament(GO:0005882)
0.0 0.5 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.5 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 0.3 GO:0044308 axonal spine(GO:0044308)
0.0 0.3 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.1 GO:0071914 prominosome(GO:0071914)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 7.0 GO:0019905 syntaxin binding(GO:0019905)
0.6 4.5 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
1.1 4.4 GO:0030151 molybdenum ion binding(GO:0030151)
0.1 3.5 GO:0045296 cadherin binding(GO:0045296)
0.0 3.2 GO:0030674 protein binding, bridging(GO:0030674)
0.7 3.0 GO:0038025 reelin receptor activity(GO:0038025)
0.1 2.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 2.4 GO:0005112 Notch binding(GO:0005112)
0.1 1.9 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 1.9 GO:0008083 growth factor activity(GO:0008083)
0.3 1.8 GO:0015616 DNA translocase activity(GO:0015616)
0.5 1.5 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.0 1.5 GO:0017048 Rho GTPase binding(GO:0017048)
0.3 1.0 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.0 0.7 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 0.6 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.1 0.6 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0 0.6 GO:0005504 fatty acid binding(GO:0005504)
0.2 0.5 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 0.4 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)