Motif ID: Hmga2

Z-value: 1.412


Transcription factors associated with Hmga2:

Gene SymbolEntrez IDGene Name
Hmga2 ENSMUSG00000056758.8 Hmga2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hmga2mm10_v2_chr10_-_120476469_120476527-0.368.9e-02Click!


Activity profile for motif Hmga2.

activity profile for motif Hmga2


Sorted Z-values histogram for motif Hmga2

Sorted Z-values for motif Hmga2



Network of associatons between targets according to the STRING database.



First level regulatory network of Hmga2

PNG image of the network

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Top targets:


Showing 1 to 20 of 140 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_98667264 9.648 ENSMUST00000099683.1
 Gm10800
predicted gene 10800
chr9_+_3013140 9.232 ENSMUST00000143083.2
 Gm10721
predicted gene 10721
chr14_-_19418930 8.767 ENSMUST00000177817.1
 Gm21738
predicted gene, 21738
chr9_+_3004457 6.768 ENSMUST00000178348.1
 Gm11168
predicted gene 11168
chr9_+_3023547 6.189 ENSMUST00000099046.3
 Gm10718
predicted gene 10718
chr9_+_3025417 5.918 ENSMUST00000075573.6
 Gm10717
predicted gene 10717
chr9_+_3017408 5.289 ENSMUST00000099049.3
 Gm10719
predicted gene 10719
chr9_+_3018753 5.205 ENSMUST00000179272.1
 Gm10719
predicted gene 10719
chr11_-_102897123 4.613 ENSMUST00000067444.3
 Gfap
glial fibrillary acidic protein
chr16_-_43979050 3.348 ENSMUST00000165648.1
ENSMUST00000036321.7
 Zdhhc23

zinc finger, DHHC domain containing 23

chr11_-_102897146 3.251 ENSMUST00000077902.4
 Gfap
glial fibrillary acidic protein
chr4_+_44756609 2.410 ENSMUST00000143385.1
 Zcchc7
zinc finger, CCHC domain containing 7
chr4_+_44756553 2.381 ENSMUST00000107824.2
 Zcchc7
zinc finger, CCHC domain containing 7
chr13_-_62371936 2.262 ENSMUST00000107989.3
 Gm3604
predicted gene 3604
chr4_-_32923455 2.146 ENSMUST00000035719.4
ENSMUST00000084749.1
 Ankrd6

ankyrin repeat domain 6

chr12_-_23780265 1.884 ENSMUST00000072014.4
 Gm10330
predicted gene 10330
chr2_+_62664279 1.867 ENSMUST00000028257.2
 Gca
grancalcin
chr4_+_103114712 1.776 ENSMUST00000143417.1
 Mier1
mesoderm induction early response 1 homolog (Xenopus laevis
chr5_-_106926245 1.507 ENSMUST00000117588.1
 Hfm1
HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)
chr18_+_37447641 1.370 ENSMUST00000052387.3
 Pcdhb14
protocadherin beta 14

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 58 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.3 7.9 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
0.1 3.3 GO:0018345 protein palmitoylation(GO:0018345)
0.6 2.4 GO:0042938 dipeptide transport(GO:0042938)
0.1 2.1 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.6 1.8 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 1.8 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.1 1.7 GO:0035635 entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.0 1.6 GO:0001578 microtubule bundle formation(GO:0001578)
0.2 1.5 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 1.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.2 1.2 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.1 1.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 1.1 GO:1900153 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 1.1 GO:0006862 nucleotide transport(GO:0006862)
0.0 1.1 GO:0034605 cellular response to heat(GO:0034605)
0.2 1.0 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 1.0 GO:2000598 regulation of cyclin catabolic process(GO:2000598) negative regulation of cyclin catabolic process(GO:2000599)
0.1 1.0 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.1 1.0 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.1 0.9 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.0 7.9 GO:0097450 astrocyte end-foot(GO:0097450)
0.2 1.7 GO:0032584 growth cone membrane(GO:0032584)
0.1 1.2 GO:0070688 MLL5-L complex(GO:0070688)
0.0 1.2 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 1.2 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.9 GO:0030014 CCR4-NOT complex(GO:0030014)
0.2 0.8 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.8 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.8 GO:0035145 exon-exon junction complex(GO:0035145)
0.2 0.7 GO:0036156 inner dynein arm(GO:0036156)
0.2 0.7 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.1 0.5 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 0.4 GO:0044316 cone cell pedicle(GO:0044316)
0.1 0.3 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.0 0.2 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.1 GO:0070469 respiratory chain(GO:0070469)
0.0 0.1 GO:0061702 inflammasome complex(GO:0061702)
0.0 0.1 GO:0044299 C-fiber(GO:0044299)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 38 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 7.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 3.3 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.5 2.4 GO:0042895 antibiotic transporter activity(GO:0042895)
0.1 1.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 1.3 GO:0035064 methylated histone binding(GO:0035064)
0.4 1.2 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.4 1.2 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.1 1.1 GO:0015215 nucleotide transmembrane transporter activity(GO:0015215)
0.3 1.0 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.1 1.0 GO:0005537 mannose binding(GO:0005537)
0.0 1.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.0 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.9 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.8 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.8 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 0.7 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.6 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.6 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.6 GO:0046875 ephrin receptor binding(GO:0046875)