Motif ID: Zbtb12

Z-value: 0.395


Transcription factors associated with Zbtb12:

Gene SymbolEntrez IDGene Name
Zbtb12 ENSMUSG00000049823.8 Zbtb12

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zbtb12mm10_v2_chr17_+_34894515_34894573-0.058.4e-01Click!


Activity profile for motif Zbtb12.

activity profile for motif Zbtb12


Sorted Z-values histogram for motif Zbtb12

Sorted Z-values for motif Zbtb12



Network of associatons between targets according to the STRING database.



First level regulatory network of Zbtb12

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_15375969 1.314 ENSMUST00000014917.7
Dll1
delta-like 1 (Drosophila)
chr8_-_45382198 0.824 ENSMUST00000093526.6
Fam149a
family with sequence similarity 149, member A
chr2_-_28916668 0.792 ENSMUST00000113847.1
Barhl1
BarH-like 1 (Drosophila)
chr11_-_12027958 0.694 ENSMUST00000109654.1
Grb10
growth factor receptor bound protein 10
chr5_+_30281377 0.655 ENSMUST00000101448.3
Drc1
dynein regulatory complex subunit 1
chr10_-_70592782 0.640 ENSMUST00000162251.1
Phyhipl
phytanoyl-CoA hydroxylase interacting protein-like
chr11_+_54902917 0.595 ENSMUST00000149324.1
Gpx3
glutathione peroxidase 3
chr5_+_92603039 0.589 ENSMUST00000050952.3
Stbd1
starch binding domain 1
chr3_+_5218516 0.571 ENSMUST00000175866.1
Zfhx4
zinc finger homeodomain 4
chr11_+_54902743 0.561 ENSMUST00000082430.3
Gpx3
glutathione peroxidase 3
chr19_+_59260878 0.555 ENSMUST00000026084.3
Slc18a2
solute carrier family 18 (vesicular monoamine), member 2
chr3_+_5218546 0.539 ENSMUST00000026284.6
Zfhx4
zinc finger homeodomain 4
chr18_-_70472429 0.524 ENSMUST00000067556.3
4930503L19Rik
RIKEN cDNA 4930503L19 gene
chr3_+_5218589 0.479 ENSMUST00000177488.1
Zfhx4
zinc finger homeodomain 4
chr4_-_149909719 0.456 ENSMUST00000105685.1
Spsb1
splA/ryanodine receptor domain and SOCS box containing 1
chr13_+_104229366 0.409 ENSMUST00000022227.6
Cenpk
centromere protein K
chr9_+_57827284 0.379 ENSMUST00000163186.1
Gm17231
predicted gene 17231
chr11_-_88718078 0.376 ENSMUST00000092794.5
Msi2
musashi RNA-binding protein 2
chr6_+_108065035 0.361 ENSMUST00000049246.6
Setmar
SET domain without mariner transposase fusion
chr14_-_79481268 0.355 ENSMUST00000022601.5
Wbp4
WW domain binding protein 4
chr3_+_88081997 0.338 ENSMUST00000071812.5
Iqgap3
IQ motif containing GTPase activating protein 3
chr18_-_46728342 0.331 ENSMUST00000035804.7
Cdo1
cysteine dioxygenase 1, cytosolic
chr6_+_37900477 0.294 ENSMUST00000120238.1
Trim24
tripartite motif-containing 24
chr7_+_92875253 0.276 ENSMUST00000076052.6
Prcp
prolylcarboxypeptidase (angiotensinase C)
chr11_+_98446826 0.265 ENSMUST00000019456.4
Grb7
growth factor receptor bound protein 7
chr4_-_45489794 0.263 ENSMUST00000146236.1
Shb
src homology 2 domain-containing transforming protein B
chr1_+_69826986 0.254 ENSMUST00000065425.5
ENSMUST00000113940.2
Spag16

sperm associated antigen 16

chr6_-_124814288 0.249 ENSMUST00000172132.2
Tpi1
triosephosphate isomerase 1
chr11_-_3409162 0.249 ENSMUST00000101638.3
Limk2
LIM motif-containing protein kinase 2
chr15_+_89499598 0.233 ENSMUST00000109309.1
Shank3
SH3/ankyrin domain gene 3
chr15_+_102503722 0.228 ENSMUST00000096145.4
Gm10337
predicted gene 10337
chr1_+_37997975 0.199 ENSMUST00000027252.7
Eif5b
eukaryotic translation initiation factor 5B
chr7_+_101317073 0.198 ENSMUST00000163799.2
ENSMUST00000164479.2
Stard10

START domain containing 10

chr4_-_119173849 0.197 ENSMUST00000052715.4
ENSMUST00000179290.1
ENSMUST00000154226.1
Zfp691


zinc finger protein 691


chr5_+_67260696 0.180 ENSMUST00000161233.1
ENSMUST00000160352.1
Tmem33

transmembrane protein 33

chrX_-_140956675 0.171 ENSMUST00000033805.8
ENSMUST00000112978.1
Psmd10

proteasome (prosome, macropain) 26S subunit, non-ATPase, 10

chr12_+_105784694 0.158 ENSMUST00000109901.2
ENSMUST00000168186.1
ENSMUST00000163473.1
ENSMUST00000170540.1
ENSMUST00000166735.1
ENSMUST00000170002.1
Papola





poly (A) polymerase alpha





chr7_-_141918481 0.147 ENSMUST00000151890.1
Tollip
toll interacting protein
chr14_+_79481164 0.133 ENSMUST00000040131.5
Elf1
E74-like factor 1
chr3_-_131344892 0.129 ENSMUST00000090246.4
ENSMUST00000126569.1
Sgms2

sphingomyelin synthase 2

chr15_-_79546741 0.120 ENSMUST00000054014.7
Ddx17
DEAD (Asp-Glu-Ala-Asp) box polypeptide 17
chr17_+_27909337 0.119 ENSMUST00000114842.1
ENSMUST00000025058.7
ENSMUST00000088027.5
Anks1


ankyrin repeat and SAM domain containing 1


chr17_+_17831004 0.115 ENSMUST00000172097.2
4930546H06Rik
RIKEN cDNA 4930546H06 gene
chr12_-_101958148 0.114 ENSMUST00000159883.1
ENSMUST00000160251.1
ENSMUST00000161011.1
ENSMUST00000021606.5
Atxn3



ataxin 3



chr4_+_32983417 0.112 ENSMUST00000084747.5
Rragd
Ras-related GTP binding D
chr3_-_130061553 0.112 ENSMUST00000168675.1
Sec24b
Sec24 related gene family, member B (S. cerevisiae)
chr5_+_122850186 0.110 ENSMUST00000031434.6
Rnf34
ring finger protein 34
chr2_+_31759993 0.096 ENSMUST00000124089.1
Abl1
c-abl oncogene 1, non-receptor tyrosine kinase
chr11_-_59228162 0.088 ENSMUST00000163300.1
ENSMUST00000061242.7
Arf1

ADP-ribosylation factor 1

chr5_-_24447587 0.083 ENSMUST00000127194.1
ENSMUST00000115033.1
ENSMUST00000123167.1
ENSMUST00000030799.8
Tmub1



transmembrane and ubiquitin-like domain containing 1



chr2_+_31759932 0.083 ENSMUST00000028190.6
Abl1
c-abl oncogene 1, non-receptor tyrosine kinase
chr5_+_95956916 0.079 ENSMUST00000023840.5
Cxcl13
chemokine (C-X-C motif) ligand 13
chr15_+_82341179 0.070 ENSMUST00000050349.2
Fam109b
family with sequence similarity 109, member B
chr19_-_46573059 0.063 ENSMUST00000026009.8
Arl3
ADP-ribosylation factor-like 3
chr13_+_76098734 0.057 ENSMUST00000091466.3
Ttc37
tetratricopeptide repeat domain 37
chr11_+_69991061 0.049 ENSMUST00000018711.8
Gabarap
gamma-aminobutyric acid receptor associated protein
chr19_-_10240689 0.048 ENSMUST00000088013.5
Myrf
myelin regulatory factor
chr17_-_27909206 0.047 ENSMUST00000114848.1
Taf11
TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr17_-_32189457 0.040 ENSMUST00000087721.3
ENSMUST00000162117.1
Ephx3

epoxide hydrolase 3

chr7_-_127993831 0.039 ENSMUST00000033056.3
Pycard
PYD and CARD domain containing
chr3_-_84155762 0.031 ENSMUST00000047368.6
Mnd1
meiotic nuclear divisions 1 homolog (S. cerevisiae)
chr9_-_78481724 0.030 ENSMUST00000042235.8
Eef1a1
eukaryotic translation elongation factor 1 alpha 1
chr19_-_6080311 0.024 ENSMUST00000159832.1
Vps51
vacuolar protein sorting 51 homolog (S. cerevisiae)
chr6_-_33060172 0.022 ENSMUST00000115091.1
ENSMUST00000127666.1
Chchd3

coiled-coil-helix-coiled-coil-helix domain containing 3

chr13_+_9276477 0.017 ENSMUST00000174552.1
Dip2c
DIP2 disco-interacting protein 2 homolog C (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0060853 arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) endothelial cell fate specification(GO:0060847) Notch signaling pathway involved in arterial endothelial cell fate commitment(GO:0060853) blood vessel endothelial cell fate specification(GO:0097101)
0.1 0.6 GO:0098700 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
0.1 0.2 GO:0019405 alditol catabolic process(GO:0019405) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.1 0.7 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.1 0.3 GO:0000098 sulfur amino acid catabolic process(GO:0000098) response to glucagon(GO:0033762)
0.1 0.2 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
0.1 0.2 GO:1900275 negative regulation of phospholipase C activity(GO:1900275)
0.1 0.2 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.1 1.2 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.1 0.3 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.3 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.3 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0 0.2 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 0.1 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.0 0.1 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0 0.7 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 0.3 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.1 GO:0072592 oxygen metabolic process(GO:0072592)
0.0 0.3 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154) regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.0 0.6 GO:0005980 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.1 GO:0097212 lysosomal membrane organization(GO:0097212)
0.0 0.2 GO:0032782 bile acid secretion(GO:0032782) positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0 0.1 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.4 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.8 GO:0030901 midbrain development(GO:0030901)
0.0 0.0 GO:0002586 regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002580) positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
0.0 0.3 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.1 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.6 GO:0031045 dense core granule(GO:0031045)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.1 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.3 GO:0044447 axoneme part(GO:0044447)
0.0 0.2 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.1 0.6 GO:2001069 glycogen binding(GO:2001069)
0.1 1.3 GO:0030957 Tat protein binding(GO:0030957)
0.1 1.2 GO:0008430 selenium binding(GO:0008430)
0.1 0.3 GO:0032027 myosin light chain binding(GO:0032027)
0.1 0.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.3 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.9 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.3 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.4 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0035325 Toll-like receptor binding(GO:0035325)