Motif ID: Yy1_Yy2

Z-value: 3.211

Transcription factors associated with Yy1_Yy2:

Gene SymbolEntrez IDGene Name
Yy1 ENSMUSG00000021264.11 Yy1
Yy2 ENSMUSG00000091736.2 Yy2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Yy2mm10_v2_chrX_-_157598642_157598655-0.602.4e-03Click!
Yy1mm10_v2_chr12_+_108792946_1087929880.154.9e-01Click!


Activity profile for motif Yy1_Yy2.

activity profile for motif Yy1_Yy2


Sorted Z-values histogram for motif Yy1_Yy2

Sorted Z-values for motif Yy1_Yy2



Network of associatons between targets according to the STRING database.



First level regulatory network of Yy1_Yy2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_-_22163299 12.946 ENSMUST00000100052.4
 Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
chr11_-_63922257 8.376 ENSMUST00000094103.3
 Hs3st3b1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr11_+_75732869 7.647 ENSMUST00000067664.3
 Ywhae
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
chr14_-_37098211 6.251 ENSMUST00000022337.9
 Cdhr1
cadherin-related family member 1
chr17_-_23829095 6.197 ENSMUST00000069579.5
 Tceb2
transcription elongation factor B (SIII), polypeptide 2
chr9_-_97018823 5.924 ENSMUST00000055433.4
 Spsb4
splA/ryanodine receptor domain and SOCS box containing 4
chr11_+_94741782 5.915 ENSMUST00000021240.6
 Cdc34-ps
cell division cycle 34 homolog, pseudogene (S. cerevisiae)
chr19_+_25610533 5.897 ENSMUST00000048935.4
 Dmrt3
doublesex and mab-3 related transcription factor 3
chr11_+_75733037 5.895 ENSMUST00000131398.1
 Ywhae
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
chr19_-_50030735 5.627 ENSMUST00000071866.1
 Rpl13a-ps1
ribosomal protein 13A, pseudogene 1
chr3_-_90213577 5.581 ENSMUST00000170122.2
 Rps27
ribosomal protein S27
chr5_-_53707532 5.530 ENSMUST00000031093.3
 Cckar
cholecystokinin A receptor
chr12_+_16810940 5.412 ENSMUST00000020908.7
 E2f6
E2F transcription factor 6
chr18_+_56707725 5.369 ENSMUST00000025486.8
 Lmnb1
lamin B1
chr11_-_66525964 5.358 ENSMUST00000066679.6
 Shisa6
shisa homolog 6 (Xenopus laevis)
chr5_-_144761633 5.328 ENSMUST00000061446.7
 Tmem130
transmembrane protein 130
chr9_+_34904913 5.200 ENSMUST00000045091.6
 Kirrel3
kin of IRRE like 3 (Drosophila)
chr12_-_108003594 5.030 ENSMUST00000066060.4
 Bcl11b
B cell leukemia/lymphoma 11B
chr1_-_186117251 5.025 ENSMUST00000045388.7
 Lyplal1
lysophospholipase-like 1
chr1_+_153652943 5.001 ENSMUST00000041776.5
 Rgs8
regulator of G-protein signaling 8

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 871 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 32.6 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.4 21.8 GO:0032543 mitochondrial translation(GO:0032543)
0.1 17.1 GO:0042254 ribosome biogenesis(GO:0042254)
0.8 16.7 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.8 13.7 GO:0043248 proteasome assembly(GO:0043248)
2.7 13.4 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.1 13.0 GO:0051028 mRNA transport(GO:0051028)
1.1 12.8 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.3 12.2 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.2 12.2 GO:0006413 translational initiation(GO:0006413)
0.4 12.0 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.9 11.7 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
1.6 11.1 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
1.6 9.8 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
1.0 9.3 GO:0031424 keratinization(GO:0031424)
0.3 9.1 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.4 9.0 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 8.9 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
2.1 8.5 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.3 8.4 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 359 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 48.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.7 36.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 32.5 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.8 26.9 GO:0000788 nuclear nucleosome(GO:0000788)
0.6 26.7 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.5 23.4 GO:0000786 nucleosome(GO:0000786)
0.6 21.4 GO:0015935 small ribosomal subunit(GO:0015935)
0.5 20.7 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 19.4 GO:0005730 nucleolus(GO:0005730)
0.2 18.0 GO:0043195 terminal bouton(GO:0043195)
0.8 17.6 GO:0005839 proteasome core complex(GO:0005839)
0.2 13.8 GO:0005871 kinesin complex(GO:0005871)
0.3 11.1 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.2 10.3 GO:0005840 ribosome(GO:0005840)
0.8 10.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.2 9.7 GO:0008180 COP9 signalosome(GO:0008180)
1.8 9.1 GO:0032133 chromosome passenger complex(GO:0032133)
0.4 9.1 GO:0071565 nBAF complex(GO:0071565)
1.0 9.0 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.3 9.0 GO:0032839 dendrite cytoplasm(GO:0032839)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 500 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 125.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.4 28.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
1.4 22.3 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.3 20.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.8 16.9 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
1.7 13.8 GO:0050815 phosphoserine binding(GO:0050815)
0.3 13.3 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.4 11.0 GO:0003954 NADH dehydrogenase activity(GO:0003954)
0.3 10.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
1.7 10.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.4 10.3 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.2 9.8 GO:0008536 Ran GTPase binding(GO:0008536)
0.8 9.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.4 9.0 GO:0003785 actin monomer binding(GO:0003785)
0.3 8.8 GO:0008432 JUN kinase binding(GO:0008432)
1.7 8.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.6 8.5 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
1.4 8.4 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
1.6 7.8 GO:0005344 oxygen transporter activity(GO:0005344)
0.4 7.8 GO:0055103 ligase regulator activity(GO:0055103)