Motif ID: Relb

Z-value: 0.738


Transcription factors associated with Relb:

Gene SymbolEntrez IDGene Name
Relb ENSMUSG00000002983.10 Relb

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Relbmm10_v2_chr7_-_19629355_196294510.453.1e-02Click!


Activity profile for motif Relb.

activity profile for motif Relb


Sorted Z-values histogram for motif Relb

Sorted Z-values for motif Relb



Network of associatons between targets according to the STRING database.



First level regulatory network of Relb

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_107760221 4.188 ENSMUST00000153114.1
ENSMUST00000118593.1
ENSMUST00000120243.1
 Csf1


colony stimulating factor 1 (macrophage)


chr14_+_80000292 3.568 ENSMUST00000088735.3
 Olfm4
olfactomedin 4
chr9_+_64385626 3.235 ENSMUST00000093829.2
ENSMUST00000118485.1
ENSMUST00000164113.1
 Megf11


multiple EGF-like-domains 11


chr9_+_64385675 2.359 ENSMUST00000068967.4
 Megf11
multiple EGF-like-domains 11
chr8_+_46739745 1.850 ENSMUST00000034041.7
 Irf2
interferon regulatory factor 2
chrX_+_141475385 1.355 ENSMUST00000112931.1
ENSMUST00000112930.1
 Col4a5

collagen, type IV, alpha 5

chr15_-_98677451 1.305 ENSMUST00000120997.1
ENSMUST00000109149.2
ENSMUST00000003451.4
 Rnd1


Rho family GTPase 1


chr3_-_9610074 1.253 ENSMUST00000041124.7
 Zfp704
zinc finger protein 704
chr4_+_129984833 1.249 ENSMUST00000120204.1
 Bai2
brain-specific angiogenesis inhibitor 2
chr4_+_129985098 1.234 ENSMUST00000106017.1
ENSMUST00000121049.1
 Bai2

brain-specific angiogenesis inhibitor 2

chr1_+_15287259 1.229 ENSMUST00000175681.1
 Kcnb2
potassium voltage gated channel, Shab-related subfamily, member 2
chr2_+_10153563 1.149 ENSMUST00000026886.7
 Itih5
inter-alpha (globulin) inhibitor H5
chr8_+_72319033 1.143 ENSMUST00000067912.7
 Klf2
Kruppel-like factor 2 (lung)
chr4_+_130915949 1.093 ENSMUST00000030316.6
 Laptm5
lysosomal-associated protein transmembrane 5
chr4_+_99715640 1.068 ENSMUST00000097961.2
ENSMUST00000107004.2
ENSMUST00000139799.1
 Alg6


asparagine-linked glycosylation 6 (alpha-1,3,-glucosyltransferase)


chr14_+_60732906 0.990 ENSMUST00000162945.1
 Spata13
spermatogenesis associated 13
chr7_+_43463145 0.987 ENSMUST00000107977.1
 Vsig10l
ZV-set and immunoglobulin domain containing 10 like
chr10_-_93310963 0.948 ENSMUST00000151153.1
 Elk3
ELK3, member of ETS oncogene family
chr2_+_59612034 0.930 ENSMUST00000112568.1
ENSMUST00000037526.4
 Tanc1

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1

chr19_+_46304709 0.907 ENSMUST00000073116.5
 Nfkb2
nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100
chr2_-_5063996 0.878 ENSMUST00000114996.1
 Optn
optineurin
chr7_-_102250086 0.870 ENSMUST00000106923.1
ENSMUST00000098230.4
 Rhog

ras homolog gene family, member G

chr13_+_83732438 0.853 ENSMUST00000182701.1
 C130071C03Rik
RIKEN cDNA C130071C03 gene
chrX_+_163909132 0.813 ENSMUST00000033734.7
ENSMUST00000112294.2
 Ap1s2

adaptor-related protein complex 1, sigma 2 subunit

chr4_-_40239779 0.798 ENSMUST00000037907.6
 Ddx58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr15_-_89170688 0.792 ENSMUST00000060808.9
 Plxnb2
plexin B2
chr18_+_37484955 0.782 ENSMUST00000053856.4
 Pcdhb17
protocadherin beta 17
chr2_-_5063932 0.766 ENSMUST00000027986.4
 Optn
optineurin
chr7_+_99535652 0.747 ENSMUST00000032995.8
ENSMUST00000162404.1
 Arrb1

arrestin, beta 1

chr16_+_97997313 0.745 ENSMUST00000122450.1
 B230307C23Rik
RIKEN cDNA B230307C23 gene
chr2_+_119972699 0.718 ENSMUST00000066058.7
 Mapkbp1
mitogen-activated protein kinase binding protein 1
chr7_-_19629355 0.713 ENSMUST00000049912.8
ENSMUST00000094762.3
ENSMUST00000098754.4
 Relb


avian reticuloendotheliosis viral (v-rel) oncogene related B


chr2_-_125506385 0.694 ENSMUST00000028633.6
 Fbn1
fibrillin 1
chr12_-_76369385 0.687 ENSMUST00000176187.1
ENSMUST00000167011.1
ENSMUST00000176967.1
 Zbtb25


zinc finger and BTB domain containing 25


chr5_+_90759299 0.684 ENSMUST00000031318.4
 Cxcl5
chemokine (C-X-C motif) ligand 5
chr17_+_35424842 0.664 ENSMUST00000174699.1
 H2-Q6
histocompatibility 2, Q region locus 6
chr11_+_90030295 0.616 ENSMUST00000092788.3
 Tmem100
transmembrane protein 100
chrX_+_36112110 0.600 ENSMUST00000033418.7
 Il13ra1
interleukin 13 receptor, alpha 1
chr7_+_99535439 0.598 ENSMUST00000098266.2
ENSMUST00000179755.1
 Arrb1

arrestin, beta 1

chr10_-_93311073 0.596 ENSMUST00000008542.5
 Elk3
ELK3, member of ETS oncogene family
chr12_-_55492587 0.566 ENSMUST00000021413.7
 Nfkbia
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
chr4_-_101265236 0.558 ENSMUST00000149297.1
ENSMUST00000102781.3
 Jak1

Janus kinase 1

chr12_-_76369586 0.550 ENSMUST00000176278.1
 Zbtb25
zinc finger and BTB domain containing 25
chr15_-_89429093 0.486 ENSMUST00000170460.1
 Chkb
choline kinase beta
chr14_+_55560480 0.474 ENSMUST00000121622.1
ENSMUST00000143431.1
ENSMUST00000150481.1
 Dcaf11


DDB1 and CUL4 associated factor 11


chr1_-_135258449 0.446 ENSMUST00000003135.7
 Elf3
E74-like factor 3
chr7_-_45920830 0.427 ENSMUST00000164119.1
 Emp3
epithelial membrane protein 3
chr18_+_36559972 0.414 ENSMUST00000134146.1
 Ankhd1
ankyrin repeat and KH domain containing 1
chr2_+_18672384 0.407 ENSMUST00000171845.1
ENSMUST00000061158.4
 Commd3

COMM domain containing 3

chrX_+_163908982 0.390 ENSMUST00000069041.8
 Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr15_-_79164477 0.390 ENSMUST00000040019.4
 Sox10
SRY-box containing gene 10
chr17_+_74717743 0.373 ENSMUST00000024882.6
 Ttc27
tetratricopeptide repeat domain 27
chr4_-_91399984 0.363 ENSMUST00000102799.3
 Elavl2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr7_+_28766747 0.354 ENSMUST00000170068.1
ENSMUST00000072965.4
 Sirt2

sirtuin 2

chr4_-_40239700 0.342 ENSMUST00000142055.1
 Ddx58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr18_+_36560581 0.339 ENSMUST00000155329.2
 Ankhd1
ankyrin repeat and KH domain containing 1
chr1_+_135132693 0.318 ENSMUST00000049449.4
 Ptpn7
protein tyrosine phosphatase, non-receptor type 7
chr4_+_114680769 0.292 ENSMUST00000146346.1
 Gm12829
predicted gene 12829
chr2_-_5714490 0.265 ENSMUST00000044009.7
 Camk1d
calcium/calmodulin-dependent protein kinase ID
chr1_+_135133272 0.249 ENSMUST00000167080.1
 Ptpn7
protein tyrosine phosphatase, non-receptor type 7
chr6_-_124741374 0.244 ENSMUST00000004389.5
 Grcc10
gene rich cluster, C10 gene
chr5_-_122989260 0.216 ENSMUST00000118027.1
 Kdm2b
lysine (K)-specific demethylase 2B
chr1_-_170589791 0.186 ENSMUST00000161966.1
ENSMUST00000160456.1
 Nos1ap

nitric oxide synthase 1 (neuronal) adaptor protein

chr10_+_96616998 0.182 ENSMUST00000038377.7
 Btg1
B cell translocation gene 1, anti-proliferative
chr17_+_35424870 0.179 ENSMUST00000113879.3
 H2-Q6
histocompatibility 2, Q region locus 6
chr10_-_19015347 0.171 ENSMUST00000019997.4
 Tnfaip3
tumor necrosis factor, alpha-induced protein 3
chr13_-_8940977 0.162 ENSMUST00000071184.2
 Rpl10a-ps2
ribosomal protein L10A, pseudogene 2
chr16_+_32914094 0.156 ENSMUST00000023491.6
ENSMUST00000170899.1
ENSMUST00000171118.1
ENSMUST00000170201.1
ENSMUST00000165616.1
ENSMUST00000135193.2
 Lrch3





leucine-rich repeats and calponin homology (CH) domain containing 3





chr4_+_100776664 0.148 ENSMUST00000030257.8
ENSMUST00000097955.2
 Cachd1

cache domain containing 1

chr5_-_122989086 0.109 ENSMUST00000046073.9
 Kdm2b
lysine (K)-specific demethylase 2B
chr11_-_84870712 0.105 ENSMUST00000170741.1
ENSMUST00000172405.1
ENSMUST00000100686.3
ENSMUST00000108081.2
 Ggnbp2



gametogenetin binding protein 2



chr11_-_84870646 0.099 ENSMUST00000018547.2
 Ggnbp2
gametogenetin binding protein 2
chr12_-_84194007 0.067 ENSMUST00000110294.1
 Elmsan1
ELM2 and Myb/SANT-like domain containing 1
chr16_-_55838827 0.044 ENSMUST00000096026.2
ENSMUST00000036273.6
ENSMUST00000114457.1
 Nfkbiz


nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta


chr7_-_99626936 0.010 ENSMUST00000178124.1
 Gm4980
predicted gene 4980
chr7_-_28766469 0.006 ENSMUST00000085851.5
ENSMUST00000032815.4
 Nfkbib

nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta

chr12_+_102948843 0.003 ENSMUST00000101099.5
 Unc79
unc-79 homolog (C. elegans)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.2 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.4 1.6 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.3 1.1 GO:0009597 detection of virus(GO:0009597)
0.2 0.7 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
0.2 0.7 GO:0070944 neutrophil mediated killing of bacterium(GO:0070944)
0.2 5.6 GO:0010842 retina layer formation(GO:0010842)
0.2 1.3 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393) follicle-stimulating hormone signaling pathway(GO:0042699)
0.2 1.1 GO:0071499 response to laminar fluid shear stress(GO:0034616) cellular response to laminar fluid shear stress(GO:0071499)
0.1 0.7 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.1 0.7 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.6 GO:0036015 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.1 1.3 GO:0016322 neuron remodeling(GO:0016322)
0.1 1.1 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.1 1.4 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1 0.4 GO:0061428 positive regulation of oocyte development(GO:0060282) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.1 3.6 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 0.6 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.1 0.5 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 0.3 GO:0021993 initiation of neural tube closure(GO:0021993)
0.1 0.9 GO:0002467 germinal center formation(GO:0002467)
0.1 0.2 GO:2000170 positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
0.1 0.7 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.1 0.9 GO:0097062 dendritic spine maintenance(GO:0097062)
0.1 0.8 GO:1902287 semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.0 0.2 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 1.1 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.9 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.0 0.3 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.4 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.4 GO:0048484 enteric nervous system development(GO:0048484)
0.0 1.2 GO:0036465 synaptic vesicle recycling(GO:0036465)
0.0 0.4 GO:0032060 bleb assembly(GO:0032060)
0.0 1.2 GO:0072661 protein targeting to plasma membrane(GO:0072661)
0.0 0.8 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 1.0 GO:0046847 filopodium assembly(GO:0046847)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.2 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.3 1.4 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.3 3.6 GO:0042581 specific granule(GO:0042581)
0.2 1.6 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 1.3 GO:0031143 pseudopodium(GO:0031143)
0.1 0.8 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 0.8 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.4 GO:0033010 paranodal junction(GO:0033010)
0.1 0.7 GO:0001527 microfibril(GO:0001527)
0.0 0.4 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 1.2 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 2.1 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 1.2 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.4 1.5 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.2 1.6 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.1 0.5 GO:0004103 choline kinase activity(GO:0004103)
0.1 0.4 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739) tubulin deacetylase activity(GO:0042903)
0.1 3.6 GO:0045296 cadherin binding(GO:0045296)
0.1 0.6 GO:0005131 growth hormone receptor binding(GO:0005131)
0.1 0.8 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 0.8 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.6 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 4.2 GO:0005125 cytokine activity(GO:0005125)
0.0 1.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 1.0 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 1.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 1.1 GO:0042281 dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0042281)
0.0 1.1 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 1.2 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.6 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 1.3 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 3.9 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)