Motif ID: Hoxb2_Dlx2

Z-value: 0.599

Transcription factors associated with Hoxb2_Dlx2:

Gene SymbolEntrez IDGene Name
Dlx2 ENSMUSG00000023391.7 Dlx2
Hoxb2 ENSMUSG00000075588.5 Hoxb2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Dlx2mm10_v2_chr2_-_71546745_715467580.405.8e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxb2_Dlx2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_139543889 10.064 ENSMUST00000174792.1
ENSMUST00000031523.8
Uncx

UNC homeobox

chr6_+_8948608 4.203 ENSMUST00000160300.1
Nxph1
neurexophilin 1
chr6_-_23248264 3.661 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr12_+_38783503 3.010 ENSMUST00000159334.1
Etv1
ets variant gene 1
chr12_+_38780284 2.977 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
Etv1


ets variant gene 1


chr12_+_38780817 2.977 ENSMUST00000160856.1
Etv1
ets variant gene 1
chr14_-_48665098 2.242 ENSMUST00000118578.1
Otx2
orthodenticle homolog 2 (Drosophila)
chr2_-_72986716 2.091 ENSMUST00000112062.1
Gm11084
predicted gene 11084
chr3_+_55782500 2.056 ENSMUST00000075422.4
Mab21l1
mab-21-like 1 (C. elegans)
chr10_-_45470201 1.897 ENSMUST00000079390.6
Lin28b
lin-28 homolog B (C. elegans)
chr9_-_79977782 1.740 ENSMUST00000093811.4
Filip1
filamin A interacting protein 1
chr3_-_116253467 1.717 ENSMUST00000090473.5
Gpr88
G-protein coupled receptor 88
chr3_+_125404072 1.472 ENSMUST00000173932.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr6_+_4755327 1.428 ENSMUST00000176551.1
Peg10
paternally expressed 10
chr3_-_86548268 1.395 ENSMUST00000077524.3
Mab21l2
mab-21-like 2 (C. elegans)
chr12_+_38783455 1.336 ENSMUST00000161980.1
ENSMUST00000160701.1
Etv1

ets variant gene 1

chr3_+_125404292 1.327 ENSMUST00000144344.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr3_+_134236483 1.318 ENSMUST00000181904.1
ENSMUST00000053048.9
Cxxc4

CXXC finger 4

chr13_-_114458720 1.311 ENSMUST00000022287.5
Fst
follistatin
chr4_+_8690399 1.302 ENSMUST00000127476.1
Chd7
chromodomain helicase DNA binding protein 7
chr10_-_25200110 1.279 ENSMUST00000100012.2
Akap7
A kinase (PRKA) anchor protein 7
chr1_+_109983737 1.261 ENSMUST00000172005.1
Cdh7
cadherin 7, type 2
chr1_+_110099295 1.221 ENSMUST00000134301.1
Cdh7
cadherin 7, type 2
chr6_-_147264124 1.212 ENSMUST00000052296.6
Pthlh
parathyroid hormone-like peptide
chr13_-_102906046 1.195 ENSMUST00000171791.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr10_-_6980376 1.063 ENSMUST00000105617.1
Ipcef1
interaction protein for cytohesin exchange factors 1
chr12_+_109545390 1.054 ENSMUST00000146701.1
Meg3
maternally expressed 3
chr3_-_110143937 0.998 ENSMUST00000051253.3
Ntng1
netrin G1
chr10_+_73821857 0.992 ENSMUST00000177128.1
ENSMUST00000064562.7
ENSMUST00000129404.2
ENSMUST00000105426.3
ENSMUST00000131321.2
ENSMUST00000126920.2
ENSMUST00000147189.2
ENSMUST00000105424.3
ENSMUST00000092420.6
ENSMUST00000105429.3
ENSMUST00000131724.2
ENSMUST00000152655.2
ENSMUST00000151116.2
ENSMUST00000155701.2
ENSMUST00000152819.2
ENSMUST00000125517.2
ENSMUST00000124046.1
ENSMUST00000149977.2
ENSMUST00000146682.1
ENSMUST00000177107.1
Pcdh15



















protocadherin 15



















chr12_+_38781093 0.987 ENSMUST00000161513.1
Etv1
ets variant gene 1
chr6_+_15196949 0.917 ENSMUST00000151301.1
ENSMUST00000131414.1
ENSMUST00000140557.1
ENSMUST00000115469.1
Foxp2



forkhead box P2



chr12_-_40037387 0.894 ENSMUST00000146905.1
Arl4a
ADP-ribosylation factor-like 4A
chr3_+_159839729 0.889 ENSMUST00000068952.5
Wls
wntless homolog (Drosophila)
chr12_-_31713873 0.866 ENSMUST00000057783.4
ENSMUST00000174480.2
ENSMUST00000176710.1
Gpr22


G protein-coupled receptor 22


chr13_-_58354862 0.863 ENSMUST00000043605.5
Kif27
kinesin family member 27
chr9_+_54980880 0.862 ENSMUST00000093844.3
Chrna5
cholinergic receptor, nicotinic, alpha polypeptide 5
chr13_-_102905740 0.830 ENSMUST00000167462.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr3_-_17786834 0.826 ENSMUST00000099198.2
Gm10742
predicted gene 10742
chr3_+_122044428 0.819 ENSMUST00000013995.8
Abca4
ATP-binding cassette, sub-family A (ABC1), member 4
chr3_-_88410295 0.817 ENSMUST00000056370.7
Pmf1
polyamine-modulated factor 1
chr1_+_6734827 0.809 ENSMUST00000139838.1
St18
suppression of tumorigenicity 18
chr17_+_34039437 0.799 ENSMUST00000131134.1
ENSMUST00000087497.4
ENSMUST00000114255.1
ENSMUST00000114252.1
Col11a2



collagen, type XI, alpha 2



chr8_+_23669653 0.729 ENSMUST00000042352.4
Zmat4
zinc finger, matrin type 4
chr11_-_98053415 0.698 ENSMUST00000017544.2
Stac2
SH3 and cysteine rich domain 2
chr6_-_50456085 0.688 ENSMUST00000146341.1
ENSMUST00000071728.4
Osbpl3

oxysterol binding protein-like 3

chr14_-_48662740 0.671 ENSMUST00000122009.1
Otx2
orthodenticle homolog 2 (Drosophila)
chr18_-_75697639 0.664 ENSMUST00000165559.1
Ctif
CBP80/20-dependent translation initiation factor
chr2_-_166155272 0.661 ENSMUST00000088086.3
Sulf2
sulfatase 2
chr7_+_123123870 0.649 ENSMUST00000094053.5
Tnrc6a
trinucleotide repeat containing 6a
chr2_-_166155624 0.640 ENSMUST00000109249.2
Sulf2
sulfatase 2
chr5_-_53707532 0.634 ENSMUST00000031093.3
Cckar
cholecystokinin A receptor
chr9_-_96437434 0.633 ENSMUST00000070500.2
BC043934
cDNA sequence BC043934
chr1_-_79440039 0.631 ENSMUST00000049972.4
Scg2
secretogranin II
chr19_+_24673998 0.617 ENSMUST00000057243.4
Tmem252
transmembrane protein 252
chr4_-_35845204 0.602 ENSMUST00000164772.1
ENSMUST00000065173.2
Lingo2

leucine rich repeat and Ig domain containing 2

chr1_-_89933290 0.593 ENSMUST00000036954.7
Gbx2
gastrulation brain homeobox 2
chr19_-_59170978 0.589 ENSMUST00000172821.2
Vax1
ventral anterior homeobox containing gene 1
chr6_-_124779686 0.589 ENSMUST00000147669.1
ENSMUST00000128697.1
ENSMUST00000032218.3
ENSMUST00000112475.2
Lrrc23



leucine rich repeat containing 23



chr3_-_88461182 0.588 ENSMUST00000166237.1
Sema4a
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr2_+_25372315 0.576 ENSMUST00000028329.6
ENSMUST00000114293.2
ENSMUST00000100323.2
Sapcd2


suppressor APC domain containing 2


chr3_+_76075583 0.575 ENSMUST00000160261.1
Fstl5
follistatin-like 5
chr2_+_38341068 0.564 ENSMUST00000133661.1
Lhx2
LIM homeobox protein 2
chr1_-_158356258 0.550 ENSMUST00000004133.8
Brinp2
bone morphogenic protein/retinoic acid inducible neural-specific 2
chr13_-_56252163 0.537 ENSMUST00000058475.4
Neurog1
neurogenin 1
chr8_-_61902669 0.533 ENSMUST00000121785.1
ENSMUST00000034057.7
Palld

palladin, cytoskeletal associated protein

chr2_-_71546745 0.529 ENSMUST00000024159.6
Dlx2
distal-less homeobox 2
chr4_-_43499608 0.517 ENSMUST00000136005.1
ENSMUST00000054538.6
Arhgef39

Rho guanine nucleotide exchange factor (GEF) 39

chr5_-_66514815 0.517 ENSMUST00000161879.1
ENSMUST00000159357.1
Apbb2

amyloid beta (A4) precursor protein-binding, family B, member 2

chrX_-_60893430 0.511 ENSMUST00000135107.2
Sox3
SRY-box containing gene 3
chr2_+_109917639 0.490 ENSMUST00000046548.7
ENSMUST00000111037.2
Lgr4

leucine-rich repeat-containing G protein-coupled receptor 4

chr9_+_94669876 0.488 ENSMUST00000033463.9
Slc9a9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr15_+_92597104 0.484 ENSMUST00000035399.8
Pdzrn4
PDZ domain containing RING finger 4
chr7_+_126950687 0.481 ENSMUST00000106333.1
Sez6l2
seizure related 6 homolog like 2
chr13_-_53473074 0.471 ENSMUST00000021922.8
Msx2
msh homeobox 2
chr7_+_70388305 0.468 ENSMUST00000080024.5
B130024G19Rik
RIKEN cDNA B130024G19 gene
chr5_+_27261916 0.464 ENSMUST00000101471.3
Dpp6
dipeptidylpeptidase 6
chr15_+_34238026 0.458 ENSMUST00000022867.3
Laptm4b
lysosomal-associated protein transmembrane 4B
chr3_+_122419772 0.451 ENSMUST00000029766.4
Bcar3
breast cancer anti-estrogen resistance 3
chr10_-_53647080 0.447 ENSMUST00000169866.1
Fam184a
family with sequence similarity 184, member A
chr18_+_4920509 0.445 ENSMUST00000126977.1
Svil
supervillin
chr4_+_13751297 0.442 ENSMUST00000105566.2
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr7_+_126950518 0.439 ENSMUST00000106335.1
ENSMUST00000146017.1
Sez6l2

seizure related 6 homolog like 2

chrM_+_7759 0.438 ENSMUST00000082407.1
ENSMUST00000082408.1
mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr14_+_67745229 0.436 ENSMUST00000111095.2
Gnrh1
gonadotropin releasing hormone 1
chr4_+_13743424 0.434 ENSMUST00000006761.3
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr13_-_100616911 0.423 ENSMUST00000168772.1
ENSMUST00000163163.1
ENSMUST00000022137.7
Marveld2


MARVEL (membrane-associating) domain containing 2


chr1_-_12991109 0.420 ENSMUST00000115403.2
ENSMUST00000115402.1
Slco5a1

solute carrier organic anion transporter family, member 5A1

chr7_+_51621830 0.420 ENSMUST00000032710.5
Slc17a6
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
chr4_-_132510493 0.417 ENSMUST00000030724.8
Sesn2
sestrin 2
chr15_-_79285502 0.415 ENSMUST00000165408.1
Baiap2l2
BAI1-associated protein 2-like 2
chr1_-_24612700 0.394 ENSMUST00000088336.1
Gm10222
predicted gene 10222
chr17_-_70853482 0.380 ENSMUST00000118283.1
Tgif1
TGFB-induced factor homeobox 1
chr2_-_168767136 0.379 ENSMUST00000029061.5
ENSMUST00000103074.1
Sall4

sal-like 4 (Drosophila)

chr13_-_78196373 0.372 ENSMUST00000125176.2
Nr2f1
nuclear receptor subfamily 2, group F, member 1
chr18_+_4993795 0.354 ENSMUST00000153016.1
Svil
supervillin
chr13_+_23575753 0.349 ENSMUST00000105105.1
Hist1h3d
histone cluster 1, H3d
chr7_+_126950837 0.349 ENSMUST00000106332.1
Sez6l2
seizure related 6 homolog like 2
chr17_+_34592248 0.337 ENSMUST00000038149.6
Pbx2
pre B cell leukemia homeobox 2
chr4_-_36056726 0.331 ENSMUST00000108124.3
Lingo2
leucine rich repeat and Ig domain containing 2
chr18_-_88927447 0.330 ENSMUST00000147313.1
Socs6
suppressor of cytokine signaling 6
chr6_+_30541582 0.327 ENSMUST00000096066.4
Cpa2
carboxypeptidase A2, pancreatic
chr2_+_125136692 0.322 ENSMUST00000099452.2
Ctxn2
cortexin 2
chr10_+_75037066 0.322 ENSMUST00000147802.1
ENSMUST00000020391.5
Rab36

RAB36, member RAS oncogene family

chrM_+_7005 0.321 ENSMUST00000082405.1
mt-Co2
mitochondrially encoded cytochrome c oxidase II
chr4_-_42661893 0.306 ENSMUST00000108006.3
Il11ra2
interleukin 11 receptor, alpha chain 2
chr1_+_66468364 0.294 ENSMUST00000061620.9
Unc80
unc-80 homolog (C. elegans)
chr4_+_62583568 0.292 ENSMUST00000098031.3
Rgs3
regulator of G-protein signaling 3
chr12_+_52699297 0.292 ENSMUST00000095737.3
Akap6
A kinase (PRKA) anchor protein 6
chr4_-_83285141 0.287 ENSMUST00000150522.1
Ttc39b
tetratricopeptide repeat domain 39B
chr4_-_45532470 0.283 ENSMUST00000147448.1
Shb
src homology 2 domain-containing transforming protein B
chr18_-_44662251 0.278 ENSMUST00000164666.1
Mcc
mutated in colorectal cancers
chr1_+_132298606 0.274 ENSMUST00000046071.4
Klhdc8a
kelch domain containing 8A
chr9_-_105395237 0.272 ENSMUST00000140851.1
Nek11
NIMA (never in mitosis gene a)-related expressed kinase 11
chrX_+_114474312 0.269 ENSMUST00000113371.1
ENSMUST00000040504.5
Klhl4

kelch-like 4

chr15_-_100425050 0.269 ENSMUST00000123461.1
Slc11a2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr5_+_81021202 0.266 ENSMUST00000117253.1
ENSMUST00000120128.1
Lphn3

latrophilin 3

chrM_+_9870 0.266 ENSMUST00000084013.1
mt-Nd4l
mitochondrially encoded NADH dehydrogenase 4L
chr2_+_3114220 0.265 ENSMUST00000072955.5
Fam171a1
family with sequence similarity 171, member A1
chr17_-_90088343 0.261 ENSMUST00000173917.1
Nrxn1
neurexin I
chr13_+_23544052 0.256 ENSMUST00000075558.2
Hist1h3f
histone cluster 1, H3f
chr5_+_81021583 0.248 ENSMUST00000121707.1
Lphn3
latrophilin 3
chr1_+_72284367 0.247 ENSMUST00000027380.5
ENSMUST00000141783.1
Tmem169

transmembrane protein 169

chr8_+_45658666 0.246 ENSMUST00000134675.1
ENSMUST00000139869.1
ENSMUST00000126067.1
Sorbs2


sorbin and SH3 domain containing 2


chr1_-_183147461 0.246 ENSMUST00000171366.1
Disp1
dispatched homolog 1 (Drosophila)
chr5_-_98566762 0.245 ENSMUST00000086912.4
1700010H22Rik
RIKEN cDNA 1700010H22 gene
chr2_+_71528657 0.244 ENSMUST00000126400.1
Dlx1
distal-less homeobox 1
chr3_-_154330543 0.243 ENSMUST00000184966.1
ENSMUST00000177846.2
Lhx8

LIM homeobox protein 8

chr1_-_190170671 0.242 ENSMUST00000175916.1
Prox1
prospero-related homeobox 1
chr8_+_45658731 0.235 ENSMUST00000143820.1
ENSMUST00000132139.1
Sorbs2

sorbin and SH3 domain containing 2

chr14_-_100149764 0.234 ENSMUST00000097079.4
Klf12
Kruppel-like factor 12
chr13_+_23555023 0.233 ENSMUST00000045301.6
Hist1h1d
histone cluster 1, H1d
chr9_-_55919605 0.221 ENSMUST00000037408.8
Scaper
S phase cyclin A-associated protein in the ER
chr13_-_103764502 0.214 ENSMUST00000074616.5
Srek1
splicing regulatory glutamine/lysine-rich protein 1
chr17_-_24073479 0.213 ENSMUST00000017090.5
Kctd5
potassium channel tetramerisation domain containing 5
chr11_-_69666062 0.212 ENSMUST00000108654.2
ENSMUST00000018918.5
Cd68

CD68 antigen

chr17_-_48432723 0.212 ENSMUST00000046549.3
Apobec2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr10_+_26772477 0.210 ENSMUST00000039557.7
Arhgap18
Rho GTPase activating protein 18
chr18_-_37644185 0.204 ENSMUST00000066272.4
Taf7
TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr10_-_128744014 0.201 ENSMUST00000026414.7
Dgka
diacylglycerol kinase, alpha
chr2_+_69897220 0.192 ENSMUST00000055758.9
ENSMUST00000112251.2
Ubr3

ubiquitin protein ligase E3 component n-recognin 3

chr2_-_120154600 0.190 ENSMUST00000028755.7
Ehd4
EH-domain containing 4
chr11_-_82890541 0.189 ENSMUST00000092844.6
ENSMUST00000021033.9
ENSMUST00000018985.8
Rad51d


RAD51 homolog D


chr8_-_84662841 0.189 ENSMUST00000060427.4
Ier2
immediate early response 2
chr18_+_82914632 0.188 ENSMUST00000071233.6
Zfp516
zinc finger protein 516
chr1_+_89454769 0.185 ENSMUST00000027521.8
ENSMUST00000074945.5
Agap1

ArfGAP with GTPase domain, ankyrin repeat and PH domain 1

chr1_-_190170178 0.185 ENSMUST00000177288.1
Prox1
prospero-related homeobox 1
chr5_-_138187177 0.184 ENSMUST00000110937.1
ENSMUST00000139276.1
ENSMUST00000048698.7
ENSMUST00000123415.1
Taf6



TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor



chr14_-_70642268 0.180 ENSMUST00000022697.5
Fgf17
fibroblast growth factor 17
chr2_-_174346712 0.179 ENSMUST00000168292.1
Gm20721
predicted gene, 20721
chr6_+_125552948 0.177 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
Vwf


Von Willebrand factor homolog


chr18_-_43477764 0.173 ENSMUST00000057110.9
Eif3j2
eukaryotic translation initiation factor 3, subunit J2
chr5_+_88583527 0.168 ENSMUST00000031229.6
Rufy3
RUN and FYVE domain containing 3
chr7_-_37773555 0.166 ENSMUST00000176534.1
Zfp536
zinc finger protein 536
chr3_+_89183131 0.161 ENSMUST00000140473.1
ENSMUST00000041913.6
Fam189b

family with sequence similarity 189, member B

chr18_+_23752333 0.159 ENSMUST00000170802.1
ENSMUST00000155708.1
ENSMUST00000118826.2
Mapre2


microtubule-associated protein, RP/EB family, member 2


chr3_+_55461758 0.159 ENSMUST00000070418.4
Dclk1
doublecortin-like kinase 1
chr6_+_11926758 0.159 ENSMUST00000133776.1
Phf14
PHD finger protein 14
chrX_-_134111852 0.158 ENSMUST00000033610.6
Nox1
NADPH oxidase 1
chr9_+_105395348 0.154 ENSMUST00000035181.3
Aste1
asteroid homolog 1 (Drosophila)
chr2_+_163694015 0.152 ENSMUST00000109400.2
Pkig
protein kinase inhibitor, gamma
chr2_-_121235689 0.150 ENSMUST00000142400.1
Trp53bp1
transformation related protein 53 binding protein 1
chr9_-_123678782 0.149 ENSMUST00000170591.1
ENSMUST00000171647.1
Slc6a20a

solute carrier family 6 (neurotransmitter transporter), member 20A

chr7_-_116198487 0.147 ENSMUST00000181981.1
Plekha7
pleckstrin homology domain containing, family A member 7
chr4_+_3940747 0.142 ENSMUST00000119403.1
Chchd7
coiled-coil-helix-coiled-coil-helix domain containing 7
chr12_-_57546121 0.142 ENSMUST00000044380.6
Foxa1
forkhead box A1
chr9_-_66514567 0.142 ENSMUST00000056890.8
Fbxl22
F-box and leucine-rich repeat protein 22
chrX_-_53269786 0.140 ENSMUST00000114841.1
ENSMUST00000071023.5
Fam122b

family with sequence similarity 122, member B

chr5_+_104435112 0.139 ENSMUST00000031243.8
ENSMUST00000086833.6
ENSMUST00000112748.1
ENSMUST00000112746.1
ENSMUST00000145084.1
ENSMUST00000132457.1
Spp1





secreted phosphoprotein 1





chr1_-_140183404 0.137 ENSMUST00000066859.6
ENSMUST00000111976.2
Cfh

complement component factor h

chr6_-_122340499 0.137 ENSMUST00000160843.1
Phc1
polyhomeotic-like 1 (Drosophila)
chrX_+_112604274 0.131 ENSMUST00000071814.6
Zfp711
zinc finger protein 711
chr7_-_34654342 0.131 ENSMUST00000108069.1
Kctd15
potassium channel tetramerisation domain containing 15
chr9_+_72274966 0.130 ENSMUST00000183410.1
Zfp280d
zinc finger protein 280D
chr9_+_118478344 0.129 ENSMUST00000035020.8
Eomes
eomesodermin homolog (Xenopus laevis)
chr2_-_168767029 0.128 ENSMUST00000075044.3
Sall4
sal-like 4 (Drosophila)
chr6_-_122340525 0.128 ENSMUST00000112600.2
Phc1
polyhomeotic-like 1 (Drosophila)
chr7_-_115824699 0.128 ENSMUST00000169129.1
Sox6
SRY-box containing gene 6
chr5_+_138187485 0.127 ENSMUST00000110934.2
Cnpy4
canopy 4 homolog (zebrafish)
chrX_-_102157065 0.124 ENSMUST00000056904.2
Ercc6l
excision repair cross-complementing rodent repair deficiency complementation group 6 like
chr4_-_110286581 0.124 ENSMUST00000138972.1
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr5_-_122614445 0.123 ENSMUST00000127220.1
ENSMUST00000031426.7
Ift81

intraflagellar transport 81

chr1_-_140183283 0.121 ENSMUST00000111977.1
Cfh
complement component factor h
chr9_-_105521147 0.120 ENSMUST00000176770.1
ENSMUST00000085133.6
Atp2c1

ATPase, Ca++-sequestering

chr9_+_118478182 0.118 ENSMUST00000111763.1
Eomes
eomesodermin homolog (Xenopus laevis)
chr8_+_4238815 0.117 ENSMUST00000003027.7
ENSMUST00000110999.1
Map2k7

mitogen-activated protein kinase kinase 7

chr7_-_73537621 0.116 ENSMUST00000172704.1
Chd2
chromodomain helicase DNA binding protein 2
chr11_+_101582236 0.115 ENSMUST00000039581.7
ENSMUST00000100403.2
ENSMUST00000107194.1
ENSMUST00000128614.1
Tmem106a



transmembrane protein 106A



chr7_+_35802593 0.114 ENSMUST00000052454.2
E130304I02Rik
RIKEN cDNA E130304I02 gene
chr6_+_134981998 0.113 ENSMUST00000167323.1
Apold1
apolipoprotein L domain containing 1
chr11_+_98798653 0.109 ENSMUST00000037930.6
Msl1
male-specific lethal 1 homolog (Drosophila)
chr8_+_4238733 0.107 ENSMUST00000110998.2
ENSMUST00000062686.4
Map2k7

mitogen-activated protein kinase kinase 7

chr7_-_116084635 0.104 ENSMUST00000111755.3
Gm4353
predicted gene 4353
chr10_-_86011833 0.104 ENSMUST00000105304.1
ENSMUST00000061699.5
Bpifc

BPI fold containing family C

chr9_+_72806874 0.104 ENSMUST00000055535.8
Prtg
protogenin homolog (Gallus gallus)
chr7_-_90475971 0.103 ENSMUST00000032843.7
Tmem126b
transmembrane protein 126B
chr8_-_26119125 0.100 ENSMUST00000037182.7
Hook3
hook homolog 3 (Drosophila)
chr2_+_73271925 0.100 ENSMUST00000090813.5
Sp9
trans-acting transcription factor 9
chr9_-_112187766 0.093 ENSMUST00000111872.2
ENSMUST00000164754.2
Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr2_+_32288317 0.093 ENSMUST00000131712.1
ENSMUST00000133113.1
ENSMUST00000081670.6
ENSMUST00000147707.1
ENSMUST00000129193.1
Golga2




golgi autoantigen, golgin subfamily a, 2




chr17_+_46161021 0.091 ENSMUST00000024748.7
ENSMUST00000172170.1
Gtpbp2

GTP binding protein 2


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 10.1 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.7 2.9 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.6 3.4 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.4 1.3 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.3 1.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.3 0.8 GO:0060023 soft palate development(GO:0060023)
0.3 1.6 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261) positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.3 0.8 GO:0021893 cerebral cortex GABAergic interneuron fate commitment(GO:0021893)
0.3 1.8 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.2 7.9 GO:0007638 mechanosensory behavior(GO:0007638)
0.2 0.6 GO:0090274 positive regulation of somatostatin secretion(GO:0090274)
0.2 1.9 GO:0010587 miRNA catabolic process(GO:0010587)
0.2 0.5 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.1 0.4 GO:0090425 hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.1 0.4 GO:0090526 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 1.2 GO:0043129 surfactant homeostasis(GO:0043129)
0.1 0.3 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.6 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.1 1.0 GO:0060013 righting reflex(GO:0060013)
0.1 0.9 GO:0035095 behavioral response to nicotine(GO:0035095)
0.1 0.6 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.1 0.2 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.1 0.5 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.1 0.4 GO:0033087 negative regulation of immature T cell proliferation(GO:0033087)
0.1 0.6 GO:0021546 rhombomere development(GO:0021546)
0.1 0.9 GO:0021978 telencephalon regionalization(GO:0021978)
0.1 0.1 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.1 0.5 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.9 GO:0031017 exocrine pancreas development(GO:0031017)
0.1 0.3 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.1 0.1 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.1 0.2 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.1 1.3 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.1 0.6 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 0.2 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.1 0.2 GO:0045113 regulation of integrin biosynthetic process(GO:0045113)
0.1 1.4 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.1 1.1 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.9 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.2 GO:0060539 diaphragm development(GO:0060539)
0.0 0.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.3 GO:1900194 negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.0 0.1 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.5 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.5 GO:0007530 sex determination(GO:0007530)
0.0 0.2 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.4 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 1.1 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.2 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.1 GO:0055071 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.0 0.5 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.5 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.6 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.0 0.4 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.1 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.1 GO:0036233 glycine import(GO:0036233)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.8 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.1 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 1.1 GO:0019228 neuronal action potential(GO:0019228)
0.0 1.4 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 0.4 GO:0001504 neurotransmitter uptake(GO:0001504)
0.0 0.1 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.5 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.2 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.0 0.3 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.1 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.9 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.1 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.0 0.7 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.1 GO:1900272 negative regulation of long-term synaptic potentiation(GO:1900272)
0.0 0.4 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.0 GO:0042524 negative regulation of tyrosine phosphorylation of Stat5 protein(GO:0042524)
0.0 0.2 GO:0080111 DNA demethylation(GO:0080111)
0.0 0.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.2 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.0 0.1 GO:0033280 response to vitamin D(GO:0033280)
0.0 0.0 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.3 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.4 GO:0061028 establishment of endothelial barrier(GO:0061028)
0.0 0.2 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.0 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.2 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.0 GO:0002014 vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure(GO:0002014)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.1 0.6 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.1 0.9 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 0.4 GO:0061689 paranodal junction(GO:0033010) tricellular tight junction(GO:0061689)
0.1 0.3 GO:0070826 paraferritin complex(GO:0070826)
0.1 0.4 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 0.8 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.3 GO:0071437 invadopodium(GO:0071437)
0.0 0.3 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.6 GO:0031045 dense core granule(GO:0031045)
0.0 0.4 GO:0071439 clathrin complex(GO:0071439)
0.0 0.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.4 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 1.0 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 0.9 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.3 GO:0001739 sex chromatin(GO:0001739)
0.0 1.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.2 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.7 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.5 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.7 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 1.6 GO:0030315 T-tubule(GO:0030315)
0.0 0.7 GO:0043034 costamere(GO:0043034)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.5 GO:0000786 nucleosome(GO:0000786)
0.0 0.7 GO:0005871 kinesin complex(GO:0005871)
0.0 0.2 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.8 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.2 1.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 0.7 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.1 1.3 GO:0048185 activin binding(GO:0048185)
0.1 0.3 GO:0001851 complement component C3b binding(GO:0001851)
0.1 0.9 GO:0004889 acetylcholine-activated cation-selective channel activity(GO:0004889)
0.1 1.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 1.2 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 1.6 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 0.6 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1 0.4 GO:0070728 leucine binding(GO:0070728)
0.1 0.3 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 0.8 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 0.5 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 0.2 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 0.4 GO:0050693 LBD domain binding(GO:0050693)
0.1 0.2 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 19.7 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.5 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.8 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.4 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.2 GO:0000150 recombinase activity(GO:0000150)
0.0 0.7 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.0 0.2 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.9 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.5 GO:0070888 E-box binding(GO:0070888)
0.0 0.3 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.2 GO:0015197 peptide transporter activity(GO:0015197)
0.0 0.2 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.1 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 12.0 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.0 0.7 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 0.6 GO:0042393 histone binding(GO:0042393)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.7 GO:0032934 cholesterol binding(GO:0015485) sterol binding(GO:0032934)
0.0 0.1 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.0 0.2 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.3 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.2 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)