Motif ID: Hand1
Z-value: 0.989
Transcription factors associated with Hand1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Hand1 | ENSMUSG00000037335.7 | Hand1 |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 4.6 | GO:0032804 | negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804) |
| 0.6 | 1.8 | GO:0043553 | negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) |
| 0.6 | 5.6 | GO:2001214 | positive regulation of vasculogenesis(GO:2001214) |
| 0.5 | 6.8 | GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) |
| 0.5 | 1.4 | GO:0042138 | meiotic DNA double-strand break formation(GO:0042138) |
| 0.5 | 1.4 | GO:0003278 | apoptotic process involved in heart morphogenesis(GO:0003278) |
| 0.4 | 1.3 | GO:0021557 | oculomotor nerve development(GO:0021557) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910) |
| 0.4 | 1.2 | GO:0035790 | platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) |
| 0.4 | 2.4 | GO:0042985 | negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) |
| 0.4 | 1.1 | GO:0014877 | response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
| 0.4 | 2.6 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
| 0.4 | 3.6 | GO:0090385 | phagosome-lysosome fusion(GO:0090385) |
| 0.4 | 1.4 | GO:0014043 | negative regulation of neuron maturation(GO:0014043) |
| 0.3 | 2.1 | GO:0046880 | regulation of follicle-stimulating hormone secretion(GO:0046880) follicle-stimulating hormone secretion(GO:0046884) |
| 0.3 | 1.3 | GO:0010510 | regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) |
| 0.3 | 2.0 | GO:0032815 | negative regulation of natural killer cell activation(GO:0032815) |
| 0.3 | 1.0 | GO:0071873 | response to norepinephrine(GO:0071873) |
| 0.3 | 0.9 | GO:0031117 | serotonin receptor signaling pathway(GO:0007210) positive regulation of microtubule depolymerization(GO:0031117) |
| 0.3 | 1.6 | GO:0098735 | positive regulation of the force of heart contraction(GO:0098735) |
| 0.3 | 2.3 | GO:0051639 | actin filament network formation(GO:0051639) |
| 0.2 | 1.2 | GO:0010991 | negative regulation of SMAD protein complex assembly(GO:0010991) |
| 0.2 | 1.0 | GO:0042938 | dipeptide transport(GO:0042938) |
| 0.2 | 0.7 | GO:0071544 | diphosphoinositol polyphosphate metabolic process(GO:0071543) diphosphoinositol polyphosphate catabolic process(GO:0071544) |
| 0.2 | 0.9 | GO:0034145 | positive regulation of toll-like receptor 4 signaling pathway(GO:0034145) |
| 0.2 | 2.0 | GO:0048251 | elastic fiber assembly(GO:0048251) |
| 0.2 | 0.6 | GO:0018199 | peptidyl-glutamine modification(GO:0018199) |
| 0.2 | 0.6 | GO:0035811 | negative regulation of urine volume(GO:0035811) |
| 0.2 | 1.4 | GO:2000809 | neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) positive regulation of synaptic vesicle clustering(GO:2000809) |
| 0.2 | 1.7 | GO:1900112 | regulation of histone H3-K9 trimethylation(GO:1900112) negative regulation of histone H3-K9 trimethylation(GO:1900113) |
| 0.2 | 0.5 | GO:0002578 | negative regulation of antigen processing and presentation(GO:0002578) |
| 0.2 | 0.5 | GO:0009298 | GDP-mannose biosynthetic process(GO:0009298) |
| 0.2 | 1.2 | GO:0035092 | sperm chromatin condensation(GO:0035092) |
| 0.2 | 0.3 | GO:0042636 | negative regulation of hair cycle(GO:0042636) negative regulation of hair follicle development(GO:0051799) |
| 0.1 | 1.0 | GO:0071635 | negative regulation of transforming growth factor beta production(GO:0071635) |
| 0.1 | 0.7 | GO:2001170 | negative regulation of ATP biosynthetic process(GO:2001170) |
| 0.1 | 0.1 | GO:0034727 | lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) late nucleophagy(GO:0044805) |
| 0.1 | 1.0 | GO:0033227 | dsRNA transport(GO:0033227) |
| 0.1 | 0.8 | GO:0048549 | positive regulation of pinocytosis(GO:0048549) |
| 0.1 | 0.4 | GO:0015014 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) |
| 0.1 | 2.8 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
| 0.1 | 2.0 | GO:0090140 | regulation of mitochondrial fission(GO:0090140) |
| 0.1 | 0.4 | GO:1902260 | negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817) |
| 0.1 | 0.7 | GO:0051534 | negative regulation of NFAT protein import into nucleus(GO:0051534) |
| 0.1 | 1.3 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 0.1 | 0.3 | GO:0010724 | regulation of definitive erythrocyte differentiation(GO:0010724) |
| 0.1 | 0.3 | GO:0097500 | receptor localization to nonmotile primary cilium(GO:0097500) |
| 0.1 | 0.3 | GO:0032632 | interleukin-3 production(GO:0032632) |
| 0.1 | 1.3 | GO:0032211 | negative regulation of telomere maintenance via telomerase(GO:0032211) |
| 0.1 | 0.5 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
| 0.1 | 0.6 | GO:2001023 | regulation of response to drug(GO:2001023) |
| 0.1 | 0.4 | GO:0038032 | termination of G-protein coupled receptor signaling pathway(GO:0038032) |
| 0.1 | 2.5 | GO:0045838 | positive regulation of membrane potential(GO:0045838) |
| 0.1 | 1.4 | GO:0030220 | platelet formation(GO:0030220) |
| 0.1 | 0.4 | GO:2000987 | positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987) |
| 0.1 | 0.6 | GO:0031666 | positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666) |
| 0.1 | 0.9 | GO:0035898 | parathyroid hormone secretion(GO:0035898) |
| 0.1 | 0.4 | GO:0071372 | cellular response to follicle-stimulating hormone stimulus(GO:0071372) |
| 0.1 | 0.4 | GO:0034227 | tRNA thio-modification(GO:0034227) |
| 0.1 | 0.9 | GO:0018149 | peptide cross-linking(GO:0018149) |
| 0.1 | 1.1 | GO:0034389 | lipid particle organization(GO:0034389) |
| 0.1 | 1.1 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
| 0.1 | 1.0 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
| 0.1 | 1.2 | GO:0003148 | outflow tract septum morphogenesis(GO:0003148) |
| 0.1 | 0.4 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
| 0.1 | 0.5 | GO:0071569 | protein ufmylation(GO:0071569) |
| 0.1 | 0.4 | GO:0061718 | NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glycolytic process through glucose-1-phosphate(GO:0061622) glucose catabolic process to pyruvate(GO:0061718) |
| 0.1 | 0.2 | GO:0015712 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) |
| 0.1 | 0.3 | GO:0071955 | recycling endosome to Golgi transport(GO:0071955) |
| 0.1 | 0.1 | GO:0032714 | negative regulation of interleukin-5 production(GO:0032714) |
| 0.1 | 0.3 | GO:0021631 | optic nerve morphogenesis(GO:0021631) |
| 0.1 | 0.3 | GO:0006265 | DNA topological change(GO:0006265) |
| 0.1 | 0.3 | GO:0097091 | synaptic vesicle clustering(GO:0097091) |
| 0.1 | 0.2 | GO:0038128 | ERBB2 signaling pathway(GO:0038128) |
| 0.0 | 0.1 | GO:0002586 | regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002580) positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588) |
| 0.0 | 0.1 | GO:1903054 | negative regulation of extracellular matrix organization(GO:1903054) |
| 0.0 | 0.5 | GO:0009303 | rRNA transcription(GO:0009303) |
| 0.0 | 0.4 | GO:0006390 | transcription from mitochondrial promoter(GO:0006390) |
| 0.0 | 2.3 | GO:0021680 | cerebellar Purkinje cell layer development(GO:0021680) |
| 0.0 | 2.1 | GO:0060325 | face morphogenesis(GO:0060325) |
| 0.0 | 0.5 | GO:0051764 | actin crosslink formation(GO:0051764) |
| 0.0 | 0.5 | GO:0046036 | GTP biosynthetic process(GO:0006183) CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036) |
| 0.0 | 0.2 | GO:0006438 | valyl-tRNA aminoacylation(GO:0006438) |
| 0.0 | 0.6 | GO:0006555 | methionine metabolic process(GO:0006555) |
| 0.0 | 1.2 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
| 0.0 | 0.3 | GO:0021869 | forebrain ventricular zone progenitor cell division(GO:0021869) |
| 0.0 | 0.6 | GO:0030575 | nuclear body organization(GO:0030575) |
| 0.0 | 0.8 | GO:0060259 | regulation of feeding behavior(GO:0060259) |
| 0.0 | 0.5 | GO:0048268 | clathrin coat assembly(GO:0048268) |
| 0.0 | 0.7 | GO:0000266 | mitochondrial fission(GO:0000266) |
| 0.0 | 0.7 | GO:0046597 | negative regulation of viral entry into host cell(GO:0046597) |
| 0.0 | 0.3 | GO:0046459 | short-chain fatty acid metabolic process(GO:0046459) |
| 0.0 | 0.1 | GO:2000427 | positive regulation of apoptotic cell clearance(GO:2000427) |
| 0.0 | 0.3 | GO:0032836 | glomerular basement membrane development(GO:0032836) |
| 0.0 | 0.1 | GO:0009644 | response to high light intensity(GO:0009644) |
| 0.0 | 0.3 | GO:0060068 | vagina development(GO:0060068) |
| 0.0 | 0.8 | GO:0034198 | cellular response to amino acid starvation(GO:0034198) |
| 0.0 | 0.1 | GO:0034392 | positive regulation of synaptic transmission, dopaminergic(GO:0032226) negative regulation of smooth muscle cell apoptotic process(GO:0034392) |
| 0.0 | 0.4 | GO:2000651 | positive regulation of sodium ion transmembrane transporter activity(GO:2000651) |
| 0.0 | 0.8 | GO:0001921 | positive regulation of receptor recycling(GO:0001921) |
| 0.0 | 0.2 | GO:0000103 | sulfate assimilation(GO:0000103) |
| 0.0 | 1.2 | GO:0060193 | positive regulation of lipase activity(GO:0060193) |
| 0.0 | 0.5 | GO:0032757 | positive regulation of interleukin-8 production(GO:0032757) |
| 0.0 | 1.7 | GO:0050852 | T cell receptor signaling pathway(GO:0050852) |
| 0.0 | 2.0 | GO:0003073 | regulation of systemic arterial blood pressure(GO:0003073) |
| 0.0 | 1.8 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
| 0.0 | 0.4 | GO:0007035 | vacuolar acidification(GO:0007035) |
| 0.0 | 0.1 | GO:0072697 | protein localization to cell cortex(GO:0072697) |
| 0.0 | 0.3 | GO:0070498 | interleukin-1-mediated signaling pathway(GO:0070498) |
| 0.0 | 0.1 | GO:0006421 | asparaginyl-tRNA aminoacylation(GO:0006421) |
| 0.0 | 0.5 | GO:0006308 | DNA catabolic process(GO:0006308) |
| 0.0 | 0.3 | GO:0006465 | signal peptide processing(GO:0006465) |
| 0.0 | 0.1 | GO:0006451 | selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451) |
| 0.0 | 0.3 | GO:0035563 | positive regulation of chromatin binding(GO:0035563) |
| 0.0 | 3.0 | GO:0031032 | actomyosin structure organization(GO:0031032) |
| 0.0 | 0.4 | GO:0097352 | autophagosome maturation(GO:0097352) |
| 0.0 | 0.1 | GO:0036265 | RNA (guanine-N7)-methylation(GO:0036265) |
| 0.0 | 0.6 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
| 0.0 | 0.3 | GO:0003417 | growth plate cartilage development(GO:0003417) |
| 0.0 | 0.2 | GO:0048642 | negative regulation of skeletal muscle tissue development(GO:0048642) |
| 0.0 | 2.3 | GO:0007369 | gastrulation(GO:0007369) |
| 0.0 | 0.0 | GO:0090310 | negative regulation of methylation-dependent chromatin silencing(GO:0090310) |
| 0.0 | 0.2 | GO:0019363 | pyridine nucleotide biosynthetic process(GO:0019363) |
| 0.0 | 0.4 | GO:0030488 | tRNA methylation(GO:0030488) |
| 0.0 | 0.3 | GO:0032469 | endoplasmic reticulum calcium ion homeostasis(GO:0032469) |
| 0.0 | 1.2 | GO:0001889 | liver development(GO:0001889) |
| 0.0 | 0.1 | GO:0036159 | inner dynein arm assembly(GO:0036159) |
| 0.0 | 0.0 | GO:0021940 | regulation of cerebellar granule cell precursor proliferation(GO:0021936) positive regulation of cerebellar granule cell precursor proliferation(GO:0021940) |
| 0.0 | 0.1 | GO:0031547 | brain-derived neurotrophic factor receptor signaling pathway(GO:0031547) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
| 0.0 | 0.4 | GO:0045471 | response to ethanol(GO:0045471) |
| 0.0 | 0.4 | GO:1900087 | positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.5 | 4.6 | GO:1990667 | PCSK9-AnxA2 complex(GO:1990667) |
| 1.2 | 5.8 | GO:0005587 | collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651) |
| 0.7 | 2.1 | GO:0043512 | inhibin-betaglycan-ActRII complex(GO:0034673) inhibin A complex(GO:0043512) |
| 0.6 | 1.7 | GO:0097443 | sorting endosome(GO:0097443) |
| 0.4 | 1.3 | GO:0005967 | mitochondrial pyruvate dehydrogenase complex(GO:0005967) |
| 0.4 | 2.5 | GO:0044308 | axonal spine(GO:0044308) |
| 0.4 | 1.6 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
| 0.3 | 1.7 | GO:0033093 | Weibel-Palade body(GO:0033093) |
| 0.3 | 1.4 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.2 | 0.8 | GO:1990130 | Iml1 complex(GO:1990130) |
| 0.2 | 0.5 | GO:0043527 | tRNA methyltransferase complex(GO:0043527) |
| 0.2 | 2.6 | GO:0098644 | complex of collagen trimers(GO:0098644) |
| 0.1 | 1.2 | GO:0031254 | uropod(GO:0001931) cell trailing edge(GO:0031254) |
| 0.1 | 0.4 | GO:0032280 | symmetric synapse(GO:0032280) |
| 0.1 | 0.5 | GO:1990357 | terminal web(GO:1990357) |
| 0.1 | 2.3 | GO:0005865 | striated muscle thin filament(GO:0005865) |
| 0.1 | 1.3 | GO:0042555 | MCM complex(GO:0042555) |
| 0.1 | 0.4 | GO:0005945 | 6-phosphofructokinase complex(GO:0005945) |
| 0.1 | 1.1 | GO:0001527 | microfibril(GO:0001527) |
| 0.1 | 5.2 | GO:0031985 | Golgi cisterna(GO:0031985) |
| 0.1 | 1.6 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
| 0.1 | 0.3 | GO:0030670 | phagocytic vesicle membrane(GO:0030670) |
| 0.1 | 0.9 | GO:0043203 | axon hillock(GO:0043203) |
| 0.1 | 0.5 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
| 0.1 | 0.3 | GO:0005594 | collagen type IX trimer(GO:0005594) |
| 0.1 | 0.9 | GO:0005922 | connexon complex(GO:0005922) |
| 0.1 | 0.3 | GO:0044294 | dendritic growth cone(GO:0044294) |
| 0.1 | 0.1 | GO:0031467 | Cul7-RING ubiquitin ligase complex(GO:0031467) |
| 0.1 | 0.4 | GO:0000220 | vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) |
| 0.1 | 0.5 | GO:0089701 | U2AF(GO:0089701) |
| 0.1 | 0.5 | GO:0044352 | pinosome(GO:0044352) macropinosome(GO:0044354) |
| 0.1 | 1.0 | GO:1902710 | GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711) |
| 0.1 | 1.7 | GO:0030660 | Golgi-associated vesicle membrane(GO:0030660) |
| 0.1 | 1.7 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
| 0.1 | 0.4 | GO:0042382 | paraspeckles(GO:0042382) |
| 0.1 | 0.5 | GO:0071439 | clathrin complex(GO:0071439) |
| 0.0 | 0.4 | GO:1990909 | Wnt signalosome(GO:1990909) |
| 0.0 | 2.3 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 0.6 | GO:0031528 | microvillus membrane(GO:0031528) |
| 0.0 | 0.4 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
| 0.0 | 0.3 | GO:0031091 | platelet alpha granule(GO:0031091) |
| 0.0 | 0.8 | GO:0044224 | juxtaparanode region of axon(GO:0044224) |
| 0.0 | 0.2 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
| 0.0 | 0.1 | GO:0061702 | inflammasome complex(GO:0061702) |
| 0.0 | 0.7 | GO:0005605 | basal lamina(GO:0005605) |
| 0.0 | 0.3 | GO:0000439 | core TFIIH complex(GO:0000439) |
| 0.0 | 0.5 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
| 0.0 | 0.3 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
| 0.0 | 1.2 | GO:0097440 | apical dendrite(GO:0097440) |
| 0.0 | 1.2 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.0 | 1.3 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 0.0 | 1.2 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.0 | 1.4 | GO:0005720 | nuclear heterochromatin(GO:0005720) |
| 0.0 | 1.8 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.0 | 0.1 | GO:0044299 | C-fiber(GO:0044299) |
| 0.0 | 1.5 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.0 | 1.6 | GO:0014704 | intercalated disc(GO:0014704) |
| 0.0 | 0.8 | GO:0060170 | ciliary membrane(GO:0060170) |
| 0.0 | 0.1 | GO:0031314 | extrinsic component of mitochondrial inner membrane(GO:0031314) |
| 0.0 | 0.6 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
| 0.0 | 0.7 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.0 | 0.6 | GO:0035145 | exon-exon junction complex(GO:0035145) |
| 0.0 | 0.2 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.0 | 0.6 | GO:0000407 | pre-autophagosomal structure(GO:0000407) |
| 0.0 | 0.7 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.0 | 1.3 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.0 | 1.0 | GO:0036126 | sperm flagellum(GO:0036126) |
| 0.0 | 0.2 | GO:0030140 | trans-Golgi network transport vesicle(GO:0030140) |
| 0.0 | 0.7 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.0 | 0.4 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 4.6 | GO:0004859 | phospholipase inhibitor activity(GO:0004859) phospholipase A2 inhibitor activity(GO:0019834) |
| 0.8 | 2.3 | GO:0004720 | protein-lysine 6-oxidase activity(GO:0004720) |
| 0.6 | 1.8 | GO:0036313 | phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313) |
| 0.6 | 3.0 | GO:0038085 | vascular endothelial growth factor binding(GO:0038085) |
| 0.4 | 1.8 | GO:0042834 | peptidoglycan binding(GO:0042834) |
| 0.4 | 1.6 | GO:0086038 | calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038) |
| 0.4 | 2.5 | GO:0004971 | AMPA glutamate receptor activity(GO:0004971) |
| 0.3 | 1.3 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
| 0.3 | 1.0 | GO:0004962 | endothelin receptor activity(GO:0004962) |
| 0.3 | 2.1 | GO:0034711 | inhibin binding(GO:0034711) |
| 0.3 | 1.4 | GO:0070051 | fibrinogen binding(GO:0070051) |
| 0.3 | 1.0 | GO:0005008 | hepatocyte growth factor-activated receptor activity(GO:0005008) |
| 0.3 | 3.8 | GO:0015026 | coreceptor activity(GO:0015026) |
| 0.2 | 1.0 | GO:0031694 | alpha-2A adrenergic receptor binding(GO:0031694) |
| 0.2 | 1.2 | GO:0003945 | N-acetyllactosamine synthase activity(GO:0003945) |
| 0.2 | 1.0 | GO:0051032 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
| 0.2 | 1.4 | GO:0061505 | DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505) |
| 0.2 | 0.9 | GO:0004993 | G-protein coupled serotonin receptor activity(GO:0004993) serotonin binding(GO:0051378) serotonin receptor activity(GO:0099589) |
| 0.2 | 3.0 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 0.2 | 1.4 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 0.2 | 0.8 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
| 0.2 | 1.0 | GO:0042895 | antibiotic transporter activity(GO:0042895) |
| 0.2 | 1.7 | GO:0019865 | immunoglobulin binding(GO:0019865) |
| 0.2 | 3.3 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.2 | 2.4 | GO:0008430 | selenium binding(GO:0008430) |
| 0.2 | 3.6 | GO:0017160 | Ral GTPase binding(GO:0017160) |
| 0.1 | 2.8 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.1 | 1.3 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
| 0.1 | 3.2 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.1 | 2.1 | GO:0070182 | DNA polymerase binding(GO:0070182) |
| 0.1 | 0.7 | GO:0008486 | diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) |
| 0.1 | 0.4 | GO:0033188 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
| 0.1 | 1.7 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
| 0.1 | 0.3 | GO:0070137 | ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139) |
| 0.1 | 0.7 | GO:0043262 | adenosine-diphosphatase activity(GO:0043262) |
| 0.1 | 0.4 | GO:0003872 | 6-phosphofructokinase activity(GO:0003872) |
| 0.1 | 0.5 | GO:0032051 | clathrin light chain binding(GO:0032051) |
| 0.1 | 0.8 | GO:0016888 | endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888) |
| 0.1 | 1.1 | GO:0016805 | dipeptidase activity(GO:0016805) |
| 0.1 | 0.4 | GO:0004065 | arylsulfatase activity(GO:0004065) |
| 0.1 | 0.6 | GO:0016755 | transferase activity, transferring amino-acyl groups(GO:0016755) |
| 0.1 | 1.0 | GO:0031702 | type 1 angiotensin receptor binding(GO:0031702) |
| 0.1 | 0.8 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
| 0.1 | 2.3 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
| 0.1 | 0.5 | GO:0031628 | opioid receptor binding(GO:0031628) |
| 0.1 | 0.5 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
| 0.1 | 0.3 | GO:0005113 | patched binding(GO:0005113) |
| 0.1 | 2.4 | GO:0001540 | beta-amyloid binding(GO:0001540) |
| 0.1 | 1.0 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
| 0.1 | 0.5 | GO:0039706 | co-receptor binding(GO:0039706) |
| 0.1 | 0.4 | GO:0005004 | GPI-linked ephrin receptor activity(GO:0005004) |
| 0.0 | 1.3 | GO:0008432 | JUN kinase binding(GO:0008432) |
| 0.0 | 0.2 | GO:1990380 | Lys48-specific deubiquitinase activity(GO:1990380) |
| 0.0 | 0.9 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.0 | 0.3 | GO:0003691 | double-stranded telomeric DNA binding(GO:0003691) |
| 0.0 | 0.2 | GO:0004832 | valine-tRNA ligase activity(GO:0004832) |
| 0.0 | 0.2 | GO:0055056 | D-glucose transmembrane transporter activity(GO:0055056) |
| 0.0 | 0.1 | GO:0008176 | tRNA (guanine-N7-)-methyltransferase activity(GO:0008176) |
| 0.0 | 0.4 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
| 0.0 | 0.4 | GO:0016783 | sulfurtransferase activity(GO:0016783) |
| 0.0 | 0.8 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.0 | 0.5 | GO:0016868 | intramolecular transferase activity, phosphotransferases(GO:0016868) |
| 0.0 | 0.6 | GO:0016594 | glycine binding(GO:0016594) |
| 0.0 | 0.4 | GO:0008474 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
| 0.0 | 0.4 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
| 0.0 | 1.6 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
| 0.0 | 1.2 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.0 | 0.2 | GO:0008440 | inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) |
| 0.0 | 0.3 | GO:0008301 | DNA binding, bending(GO:0008301) |
| 0.0 | 0.5 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
| 0.0 | 0.3 | GO:0015299 | solute:proton antiporter activity(GO:0015299) |
| 0.0 | 0.6 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.0 | 1.7 | GO:0005518 | collagen binding(GO:0005518) |
| 0.0 | 0.1 | GO:0004315 | 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315) |
| 0.0 | 0.3 | GO:0015271 | outward rectifier potassium channel activity(GO:0015271) |
| 0.0 | 0.4 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) tau protein binding(GO:0048156) |
| 0.0 | 0.9 | GO:0034945 | dihydrolipoamide branched chain acyltransferase activity(GO:0004147) palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity(GO:0008951) serine O-acyltransferase activity(GO:0016412) O-succinyltransferase activity(GO:0016750) sinapoyltransferase activity(GO:0016752) O-sinapoyltransferase activity(GO:0016753) peptidyl-lysine N6-myristoyltransferase activity(GO:0018030) peptidyl-lysine N6-palmitoyltransferase activity(GO:0018031) benzoyl acetate-CoA thiolase activity(GO:0018711) 3-hydroxybutyryl-CoA thiolase activity(GO:0018712) 3-ketopimelyl-CoA thiolase activity(GO:0018713) N-palmitoyltransferase activity(GO:0019105) acyl-CoA N-acyltransferase activity(GO:0019186) protein-cysteine S-myristoyltransferase activity(GO:0019705) glucosaminyl-phosphotidylinositol O-acyltransferase activity(GO:0032216) ergosterol O-acyltransferase activity(GO:0034737) lanosterol O-acyltransferase activity(GO:0034738) naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity(GO:0034848) 2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity(GO:0034851) 2-methylhexanoyl-CoA C-acetyltransferase activity(GO:0034915) butyryl-CoA 2-C-propionyltransferase activity(GO:0034919) 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity(GO:0034945) L-2-aminoadipate N-acetyltransferase activity(GO:0043741) keto acid formate lyase activity(GO:0043806) azetidine-2-carboxylic acid acetyltransferase activity(GO:0046941) peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0052858) acetyl-CoA:L-lysine N6-acetyltransferase(GO:0090595) |
| 0.0 | 0.4 | GO:0070402 | NADPH binding(GO:0070402) |
| 0.0 | 0.6 | GO:0042162 | telomeric DNA binding(GO:0042162) |
| 0.0 | 0.1 | GO:0070700 | BMP receptor binding(GO:0070700) |
| 0.0 | 0.5 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
| 0.0 | 1.0 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 0.1 | GO:0004816 | asparagine-tRNA ligase activity(GO:0004816) |
| 0.0 | 0.2 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
| 0.0 | 0.7 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.0 | 0.1 | GO:0051525 | NFAT protein binding(GO:0051525) |
| 0.0 | 0.5 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.0 | 0.2 | GO:0034211 | JUN kinase kinase kinase activity(GO:0004706) GTP-dependent protein kinase activity(GO:0034211) |
| 0.0 | 0.2 | GO:0050308 | sugar-phosphatase activity(GO:0050308) |
| 0.0 | 0.1 | GO:0031727 | CCR2 chemokine receptor binding(GO:0031727) |
| 0.0 | 1.0 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
| 0.0 | 1.1 | GO:0008376 | acetylgalactosaminyltransferase activity(GO:0008376) |
| 0.0 | 0.6 | GO:0030145 | manganese ion binding(GO:0030145) |
| 0.0 | 0.2 | GO:0070628 | proteasome binding(GO:0070628) |
| 0.0 | 0.2 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
| 0.0 | 0.3 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 0.0 | 0.3 | GO:0042605 | peptide antigen binding(GO:0042605) |
| 0.0 | 1.4 | GO:0017048 | Rho GTPase binding(GO:0017048) |
| 0.0 | 0.4 | GO:0034930 | N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131) |
| 0.0 | 0.4 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.0 | 0.2 | GO:0001223 | transcription coactivator binding(GO:0001223) |
| 0.0 | 0.2 | GO:0052890 | oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor(GO:0052890) |
