Motif ID: Pou2f2_Pou3f1

Z-value: 1.843

Transcription factors associated with Pou2f2_Pou3f1:

Gene SymbolEntrez IDGene Name
Pou2f2 ENSMUSG00000008496.12 Pou2f2
Pou3f1 ENSMUSG00000090125.2 Pou3f1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pou3f1mm10_v2_chr4_+_124657646_124657656-0.805.5e-06Click!
Pou2f2mm10_v2_chr7_-_25132473_25132512-0.341.1e-01Click!


Activity profile for motif Pou2f2_Pou3f1.

activity profile for motif Pou2f2_Pou3f1


Sorted Z-values histogram for motif Pou2f2_Pou3f1

Sorted Z-values for motif Pou2f2_Pou3f1



Network of associatons between targets according to the STRING database.



First level regulatory network of Pou2f2_Pou3f1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_+_67234620 22.580 ENSMUST00000176029.1
 Ebf2
early B cell factor 2
chr6_+_8949670 15.154 ENSMUST00000060369.3
 Nxph1
neurexophilin 1
chr6_-_67037399 11.572 ENSMUST00000043098.6
 Gadd45a
growth arrest and DNA-damage-inducible 45 alpha
chr12_+_38781093 10.658 ENSMUST00000161513.1
 Etv1
ets variant gene 1
chr12_+_38780817 10.531 ENSMUST00000160856.1
 Etv1
ets variant gene 1
chr12_+_38780284 10.276 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
 Etv1


ets variant gene 1


chr19_+_20601958 10.245 ENSMUST00000087638.3
 Aldh1a1
aldehyde dehydrogenase family 1, subfamily A1
chr7_+_24507006 10.009 ENSMUST00000176880.1
 Zfp428
zinc finger protein 428
chr7_+_24507122 9.432 ENSMUST00000177205.1
 Zfp428
zinc finger protein 428
chr7_+_24507057 9.167 ENSMUST00000071361.6
 Zfp428
zinc finger protein 428
chr13_-_56252163 9.000 ENSMUST00000058475.4
 Neurog1
neurogenin 1
chr7_+_24507099 8.834 ENSMUST00000177228.1
 Zfp428
zinc finger protein 428
chr8_-_47990535 8.611 ENSMUST00000057561.7
 Wwc2
WW, C2 and coiled-coil domain containing 2
chr2_+_103566304 7.913 ENSMUST00000076212.3
 Abtb2
ankyrin repeat and BTB (POZ) domain containing 2
chr8_-_90908415 7.530 ENSMUST00000098517.1
 Gm6658
predicted gene 6658
chr9_+_74848437 7.403 ENSMUST00000161862.1
ENSMUST00000162089.1
ENSMUST00000160017.1
ENSMUST00000160950.1
 Gm16551


Gm20649
predicted gene 16551


predicted gene 20649
chr11_-_63922257 7.167 ENSMUST00000094103.3
 Hs3st3b1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr13_+_5861489 6.971 ENSMUST00000000080.6
 Klf6
Kruppel-like factor 6
chr13_+_23684192 6.373 ENSMUST00000018246.4
 Hist1h2bc
histone cluster 1, H2bc
chr8_+_108714644 6.220 ENSMUST00000043896.8
 Zfhx3
zinc finger homeobox 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 92 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.0 30.9 GO:0007638 mechanosensory behavior(GO:0007638)
0.3 26.8 GO:0006342 chromatin silencing(GO:0006342)
1.5 22.6 GO:0035563 positive regulation of chromatin binding(GO:0035563)
1.1 14.5 GO:0000185 activation of MAPKKK activity(GO:0000185)
1.1 13.6 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 13.3 GO:0006334 nucleosome assembly(GO:0006334)
0.2 9.1 GO:0006284 base-excision repair(GO:0006284)
1.3 9.0 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.0 8.9 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
1.7 8.6 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.5 7.9 GO:0097237 cellular response to toxic substance(GO:0097237)
1.9 7.6 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.9 7.2 GO:0006477 protein sulfation(GO:0006477)
2.1 6.2 GO:0060853 arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) endothelial cell fate specification(GO:0060847) Notch signaling pathway involved in arterial endothelial cell fate commitment(GO:0060853) blood vessel endothelial cell fate specification(GO:0097101)
2.1 6.2 GO:1904059 regulation of locomotor rhythm(GO:1904059)
1.0 5.1 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.2 4.2 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.7 4.1 GO:0097491 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491) neural crest cell migration involved in autonomic nervous system development(GO:1901166)
1.0 3.8 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.2 3.6 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 40 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.9 29.0 GO:0000788 nuclear nucleosome(GO:0000788)
0.2 9.9 GO:0000786 nucleosome(GO:0000786)
0.0 9.9 GO:0000790 nuclear chromatin(GO:0000790)
0.1 9.7 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
1.3 9.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 6.2 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1 5.5 GO:0097440 apical dendrite(GO:0097440)
0.3 5.1 GO:0043196 varicosity(GO:0043196)
0.0 5.1 GO:0016604 nuclear body(GO:0016604)
0.5 3.8 GO:0042627 chylomicron(GO:0042627)
0.0 3.6 GO:0016363 nuclear matrix(GO:0016363)
0.7 3.5 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 3.2 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 3.0 GO:0043209 myelin sheath(GO:0043209)
0.9 2.7 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.1 2.6 GO:0035102 PRC1 complex(GO:0035102)
0.0 2.3 GO:0030496 midbody(GO:0030496)
0.0 2.3 GO:0031965 nuclear membrane(GO:0031965)
0.2 2.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 1.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 54 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 49.0 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 23.6 GO:0046982 protein heterodimerization activity(GO:0046982)
0.1 9.2 GO:0001047 core promoter binding(GO:0001047)
1.0 9.1 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 8.6 GO:0032947 protein complex scaffold(GO:0032947)
1.3 7.6 GO:0001758 retinal dehydrogenase activity(GO:0001758) 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
1.2 7.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.2 7.2 GO:0070888 E-box binding(GO:0070888)
0.0 7.1 GO:0008022 protein C-terminus binding(GO:0008022)
0.9 6.6 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 6.4 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.5 5.6 GO:0030957 Tat protein binding(GO:0030957)
1.6 4.7 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.1 4.6 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.4 4.1 GO:0038191 neuropilin binding(GO:0038191)
0.0 3.9 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.3 3.6 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.3 3.4 GO:0004806 triglyceride lipase activity(GO:0004806)
0.3 3.0 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 3.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)