Motif ID: Pou2f2_Pou3f1
Z-value: 1.843
Transcription factors associated with Pou2f2_Pou3f1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Pou2f2 | ENSMUSG00000008496.12 | Pou2f2 |
Pou3f1 | ENSMUSG00000090125.2 | Pou3f1 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Pou3f1 | mm10_v2_chr4_+_124657646_124657656 | -0.80 | 5.5e-06 | Click! |
Pou2f2 | mm10_v2_chr7_-_25132473_25132512 | -0.34 | 1.1e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.1 | 6.2 | GO:0060853 | arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) endothelial cell fate specification(GO:0060847) Notch signaling pathway involved in arterial endothelial cell fate commitment(GO:0060853) blood vessel endothelial cell fate specification(GO:0097101) |
2.1 | 6.2 | GO:1904059 | regulation of locomotor rhythm(GO:1904059) |
1.9 | 7.6 | GO:0042905 | 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905) |
1.7 | 8.6 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
1.5 | 22.6 | GO:0035563 | positive regulation of chromatin binding(GO:0035563) |
1.3 | 9.0 | GO:0031536 | positive regulation of exit from mitosis(GO:0031536) |
1.2 | 3.5 | GO:0060598 | dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598) |
1.1 | 13.6 | GO:0002227 | innate immune response in mucosa(GO:0002227) |
1.1 | 14.5 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
1.1 | 2.2 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
1.0 | 5.1 | GO:0048170 | positive regulation of long-term neuronal synaptic plasticity(GO:0048170) |
1.0 | 2.9 | GO:0051892 | negative regulation of cardioblast differentiation(GO:0051892) |
1.0 | 30.9 | GO:0007638 | mechanosensory behavior(GO:0007638) |
1.0 | 3.8 | GO:0010890 | positive regulation of sequestering of triglyceride(GO:0010890) |
0.9 | 7.2 | GO:0006477 | protein sulfation(GO:0006477) |
0.7 | 2.1 | GO:0042271 | susceptibility to natural killer cell mediated cytotoxicity(GO:0042271) |
0.7 | 4.1 | GO:0097491 | trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491) neural crest cell migration involved in autonomic nervous system development(GO:1901166) |
0.6 | 2.4 | GO:0043973 | histone H3-K4 acetylation(GO:0043973) |
0.6 | 2.4 | GO:0046552 | eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552) |
0.5 | 0.5 | GO:0021612 | facial nerve structural organization(GO:0021612) |
0.5 | 1.5 | GO:0017055 | negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055) |
0.5 | 7.9 | GO:0097237 | cellular response to toxic substance(GO:0097237) |
0.5 | 3.2 | GO:0000320 | re-entry into mitotic cell cycle(GO:0000320) |
0.4 | 3.0 | GO:2000124 | regulation of endocannabinoid signaling pathway(GO:2000124) |
0.4 | 2.9 | GO:1903715 | regulation of aerobic respiration(GO:1903715) |
0.4 | 3.2 | GO:0051152 | positive regulation of smooth muscle cell differentiation(GO:0051152) |
0.4 | 2.2 | GO:0021797 | forebrain anterior/posterior pattern specification(GO:0021797) |
0.4 | 1.4 | GO:0046898 | response to cycloheximide(GO:0046898) |
0.3 | 2.7 | GO:0006003 | fructose 2,6-bisphosphate metabolic process(GO:0006003) |
0.3 | 2.3 | GO:0021555 | midbrain-hindbrain boundary morphogenesis(GO:0021555) |
0.3 | 1.6 | GO:2000065 | negative regulation of aldosterone metabolic process(GO:0032345) negative regulation of aldosterone biosynthetic process(GO:0032348) negative regulation of cortisol biosynthetic process(GO:2000065) |
0.3 | 1.5 | GO:2000255 | negative regulation of male germ cell proliferation(GO:2000255) |
0.3 | 26.8 | GO:0006342 | chromatin silencing(GO:0006342) |
0.2 | 0.7 | GO:1900149 | positive regulation of Schwann cell migration(GO:1900149) |
0.2 | 3.5 | GO:0034501 | protein localization to kinetochore(GO:0034501) |
0.2 | 4.2 | GO:0006471 | protein ADP-ribosylation(GO:0006471) |
0.2 | 1.1 | GO:0035093 | spermatogenesis, exchange of chromosomal proteins(GO:0035093) |
0.2 | 9.1 | GO:0006284 | base-excision repair(GO:0006284) |
0.2 | 1.2 | GO:0089711 | L-glutamate transmembrane transport(GO:0089711) |
0.2 | 0.7 | GO:0002322 | B cell proliferation involved in immune response(GO:0002322) |
0.2 | 3.6 | GO:0010569 | regulation of double-strand break repair via homologous recombination(GO:0010569) |
0.2 | 1.0 | GO:1900042 | positive regulation of interleukin-2 secretion(GO:1900042) |
0.2 | 2.7 | GO:0060065 | uterus development(GO:0060065) |
0.2 | 0.5 | GO:0016332 | establishment or maintenance of polarity of embryonic epithelium(GO:0016332) |
0.2 | 1.9 | GO:0090129 | positive regulation of synapse maturation(GO:0090129) |
0.2 | 1.1 | GO:0090209 | negative regulation of triglyceride metabolic process(GO:0090209) |
0.2 | 1.2 | GO:0008343 | adult feeding behavior(GO:0008343) |
0.1 | 0.4 | GO:0021529 | spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) |
0.1 | 2.4 | GO:0014049 | positive regulation of glutamate secretion(GO:0014049) |
0.1 | 13.3 | GO:0006334 | nucleosome assembly(GO:0006334) |
0.1 | 1.0 | GO:0048023 | positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378) |
0.1 | 0.4 | GO:1900365 | positive regulation of mRNA polyadenylation(GO:1900365) |
0.1 | 0.4 | GO:1901228 | positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228) |
0.1 | 0.7 | GO:2000210 | positive regulation of anoikis(GO:2000210) |
0.1 | 0.7 | GO:0002326 | B cell lineage commitment(GO:0002326) |
0.1 | 0.8 | GO:0070561 | vitamin D receptor signaling pathway(GO:0070561) |
0.1 | 2.9 | GO:0003301 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
0.1 | 1.4 | GO:0046069 | cGMP catabolic process(GO:0046069) |
0.1 | 0.6 | GO:0032625 | interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619) |
0.1 | 0.6 | GO:1902166 | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166) |
0.1 | 1.8 | GO:0010842 | retina layer formation(GO:0010842) |
0.1 | 1.6 | GO:0006359 | regulation of transcription from RNA polymerase III promoter(GO:0006359) |
0.1 | 0.2 | GO:0021759 | globus pallidus development(GO:0021759) |
0.1 | 1.2 | GO:0071625 | vocalization behavior(GO:0071625) |
0.1 | 1.6 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
0.1 | 0.4 | GO:0001696 | gastric acid secretion(GO:0001696) oxalate transport(GO:0019532) |
0.1 | 0.2 | GO:0002669 | positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913) protein K29-linked ubiquitination(GO:0035519) |
0.1 | 2.6 | GO:0032611 | interleukin-1 beta production(GO:0032611) |
0.1 | 0.9 | GO:0033234 | negative regulation of protein sumoylation(GO:0033234) |
0.0 | 0.5 | GO:0034551 | respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033) |
0.0 | 1.3 | GO:0036075 | endochondral ossification(GO:0001958) replacement ossification(GO:0036075) |
0.0 | 1.8 | GO:0043029 | T cell homeostasis(GO:0043029) |
0.0 | 0.3 | GO:0042573 | retinoic acid metabolic process(GO:0042573) |
0.0 | 0.2 | GO:0060018 | astrocyte fate commitment(GO:0060018) |
0.0 | 0.9 | GO:0030262 | cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262) |
0.0 | 2.0 | GO:0045454 | cell redox homeostasis(GO:0045454) |
0.0 | 2.2 | GO:0032330 | regulation of chondrocyte differentiation(GO:0032330) |
0.0 | 8.9 | GO:0019221 | cytokine-mediated signaling pathway(GO:0019221) |
0.0 | 1.4 | GO:0035307 | positive regulation of protein dephosphorylation(GO:0035307) |
0.0 | 0.0 | GO:0001978 | regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) |
0.0 | 1.3 | GO:0045670 | regulation of osteoclast differentiation(GO:0045670) |
0.0 | 1.1 | GO:0048821 | erythrocyte development(GO:0048821) |
0.0 | 0.2 | GO:2001214 | positive regulation of vasculogenesis(GO:2001214) |
0.0 | 0.5 | GO:0016180 | snRNA processing(GO:0016180) |
0.0 | 0.3 | GO:0031987 | locomotion involved in locomotory behavior(GO:0031987) |
0.0 | 0.4 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
0.0 | 2.3 | GO:0051297 | centrosome organization(GO:0051297) |
0.0 | 2.1 | GO:0000910 | cytokinesis(GO:0000910) |
0.0 | 2.3 | GO:0035023 | regulation of Rho protein signal transduction(GO:0035023) |
0.0 | 0.4 | GO:0030513 | positive regulation of BMP signaling pathway(GO:0030513) |
0.0 | 0.6 | GO:1900046 | regulation of blood coagulation(GO:0030193) regulation of hemostasis(GO:1900046) |
0.0 | 1.1 | GO:1903169 | regulation of calcium ion transmembrane transport(GO:1903169) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.3 | 9.1 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
0.9 | 2.7 | GO:0043540 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540) |
0.9 | 29.0 | GO:0000788 | nuclear nucleosome(GO:0000788) |
0.7 | 3.5 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
0.5 | 3.8 | GO:0042627 | chylomicron(GO:0042627) |
0.3 | 5.1 | GO:0043196 | varicosity(GO:0043196) |
0.3 | 1.0 | GO:0032437 | cuticular plate(GO:0032437) |
0.2 | 1.2 | GO:0005826 | actomyosin contractile ring(GO:0005826) |
0.2 | 9.9 | GO:0000786 | nucleosome(GO:0000786) |
0.2 | 0.9 | GO:0002111 | BRCA2-BRAF35 complex(GO:0002111) |
0.2 | 1.0 | GO:0032585 | multivesicular body membrane(GO:0032585) |
0.2 | 1.3 | GO:0005667 | transcription factor complex(GO:0005667) |
0.2 | 1.4 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
0.2 | 2.2 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
0.1 | 9.7 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
0.1 | 2.6 | GO:0035102 | PRC1 complex(GO:0035102) |
0.1 | 5.5 | GO:0097440 | apical dendrite(GO:0097440) |
0.1 | 0.7 | GO:0060091 | kinocilium(GO:0060091) |
0.1 | 0.4 | GO:0001674 | female germ cell nucleus(GO:0001674) |
0.1 | 3.2 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
0.1 | 1.1 | GO:0031430 | M band(GO:0031430) |
0.0 | 0.4 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
0.0 | 0.2 | GO:0008623 | CHRAC(GO:0008623) |
0.0 | 0.5 | GO:0042788 | polysomal ribosome(GO:0042788) |
0.0 | 3.6 | GO:0016363 | nuclear matrix(GO:0016363) |
0.0 | 0.5 | GO:0032039 | integrator complex(GO:0032039) |
0.0 | 0.8 | GO:0070822 | Sin3-type complex(GO:0070822) |
0.0 | 1.8 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
0.0 | 9.9 | GO:0000790 | nuclear chromatin(GO:0000790) |
0.0 | 1.4 | GO:0005882 | intermediate filament(GO:0005882) |
0.0 | 1.3 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
0.0 | 6.2 | GO:0045121 | membrane raft(GO:0045121) membrane microdomain(GO:0098857) |
0.0 | 2.3 | GO:0030496 | midbody(GO:0030496) |
0.0 | 5.1 | GO:0016604 | nuclear body(GO:0016604) |
0.0 | 1.5 | GO:0005814 | centriole(GO:0005814) |
0.0 | 1.0 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
0.0 | 3.0 | GO:0043209 | myelin sheath(GO:0043209) |
0.0 | 0.4 | GO:0016592 | mediator complex(GO:0016592) |
0.0 | 2.3 | GO:0031965 | nuclear membrane(GO:0031965) |
0.0 | 1.3 | GO:0000776 | kinetochore(GO:0000776) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.6 | 4.7 | GO:0003953 | NAD+ nucleosidase activity(GO:0003953) |
1.3 | 7.6 | GO:0001758 | retinal dehydrogenase activity(GO:0001758) 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028) |
1.2 | 7.2 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
1.0 | 9.1 | GO:0051575 | 5'-deoxyribose-5-phosphate lyase activity(GO:0051575) |
0.9 | 6.6 | GO:0015016 | [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016) |
0.6 | 2.2 | GO:0043515 | kinetochore binding(GO:0043515) |
0.5 | 2.2 | GO:0015183 | L-aspartate transmembrane transporter activity(GO:0015183) |
0.5 | 5.6 | GO:0030957 | Tat protein binding(GO:0030957) |
0.5 | 1.5 | GO:0002153 | steroid receptor RNA activator RNA binding(GO:0002153) |
0.4 | 1.2 | GO:0000099 | sulfur amino acid transmembrane transporter activity(GO:0000099) |
0.4 | 2.7 | GO:0070095 | fructose-6-phosphate binding(GO:0070095) |
0.4 | 4.1 | GO:0038191 | neuropilin binding(GO:0038191) |
0.4 | 1.5 | GO:0004667 | prostaglandin-D synthase activity(GO:0004667) |
0.3 | 3.6 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
0.3 | 3.4 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
0.3 | 3.0 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
0.2 | 2.4 | GO:0030274 | LIM domain binding(GO:0030274) |
0.2 | 1.4 | GO:0048101 | calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
0.2 | 2.7 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
0.2 | 1.4 | GO:0051434 | BH3 domain binding(GO:0051434) |
0.2 | 3.0 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
0.2 | 49.0 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
0.2 | 7.2 | GO:0070888 | E-box binding(GO:0070888) |
0.2 | 1.6 | GO:0070700 | BMP receptor binding(GO:0070700) |
0.1 | 2.0 | GO:0019825 | oxygen binding(GO:0019825) |
0.1 | 2.5 | GO:0070064 | proline-rich region binding(GO:0070064) |
0.1 | 4.6 | GO:0097472 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472) |
0.1 | 8.6 | GO:0032947 | protein complex scaffold(GO:0032947) |
0.1 | 2.7 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
0.1 | 0.5 | GO:0034452 | dynactin binding(GO:0034452) |
0.1 | 9.2 | GO:0001047 | core promoter binding(GO:0001047) |
0.1 | 1.8 | GO:0003785 | actin monomer binding(GO:0003785) |
0.1 | 6.4 | GO:0001228 | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
0.1 | 1.6 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
0.1 | 0.7 | GO:0043024 | ribosomal small subunit binding(GO:0043024) |
0.1 | 0.3 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
0.0 | 23.6 | GO:0046982 | protein heterodimerization activity(GO:0046982) |
0.0 | 2.0 | GO:0045182 | translation regulator activity(GO:0045182) |
0.0 | 1.0 | GO:0030506 | ankyrin binding(GO:0030506) |
0.0 | 0.4 | GO:0019531 | oxalate transmembrane transporter activity(GO:0019531) |
0.0 | 3.9 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
0.0 | 7.1 | GO:0008022 | protein C-terminus binding(GO:0008022) |
0.0 | 0.4 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
0.0 | 0.1 | GO:0004984 | olfactory receptor activity(GO:0004984) |
0.0 | 0.7 | GO:0051059 | NF-kappaB binding(GO:0051059) |
0.0 | 0.1 | GO:0043426 | MRF binding(GO:0043426) |
0.0 | 0.3 | GO:0004029 | aldehyde dehydrogenase (NAD) activity(GO:0004029) |
0.0 | 2.9 | GO:0003700 | nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700) |
0.0 | 0.4 | GO:0043747 | protein-N-terminal asparagine amidohydrolase activity(GO:0008418) UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity(GO:0008759) iprodione amidohydrolase activity(GO:0018748) (3,5-dichlorophenylurea)acetate amidohydrolase activity(GO:0018749) 4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity(GO:0034571) didemethylisoproturon amidohydrolase activity(GO:0034573) N-isopropylacetanilide amidohydrolase activity(GO:0034576) N-cyclohexylformamide amidohydrolase activity(GO:0034781) isonicotinic acid hydrazide hydrolase activity(GO:0034876) cis-aconitamide amidase activity(GO:0034882) gamma-N-formylaminovinylacetate hydrolase activity(GO:0034885) N2-acetyl-L-lysine deacetylase activity(GO:0043747) O-succinylbenzoate synthase activity(GO:0043748) indoleacetamide hydrolase activity(GO:0043864) N-acetylcitrulline deacetylase activity(GO:0043909) N-acetylgalactosamine-6-phosphate deacetylase activity(GO:0047419) diacetylchitobiose deacetylase activity(GO:0052773) chitooligosaccharide deacetylase activity(GO:0052790) |
0.0 | 0.2 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
0.0 | 0.5 | GO:0017091 | AU-rich element binding(GO:0017091) |
0.0 | 1.2 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
0.0 | 2.4 | GO:0008017 | microtubule binding(GO:0008017) |
0.0 | 1.3 | GO:0051015 | actin filament binding(GO:0051015) |