Motif ID: Smarcc1_Fosl1

Z-value: 0.758

Transcription factors associated with Smarcc1_Fosl1:

Gene SymbolEntrez IDGene Name
Fosl1 ENSMUSG00000024912.5 Fosl1
Smarcc1 ENSMUSG00000032481.10 Smarcc1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Smarcc1mm10_v2_chr9_+_110132015_110132102-0.301.7e-01Click!
Fosl1mm10_v2_chr19_+_5447692_54477110.203.7e-01Click!


Activity profile for motif Smarcc1_Fosl1.

activity profile for motif Smarcc1_Fosl1


Sorted Z-values histogram for motif Smarcc1_Fosl1

Sorted Z-values for motif Smarcc1_Fosl1



Network of associatons between targets according to the STRING database.



First level regulatory network of Smarcc1_Fosl1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_33907721 1.681 ENSMUST00000115161.1
ENSMUST00000062289.8
 Bend6

BEN domain containing 6

chr18_-_66860458 1.268 ENSMUST00000057942.2
 Mc4r
melanocortin 4 receptor
chr7_-_79386943 1.109 ENSMUST00000053718.8
ENSMUST00000179243.1
 Rlbp1

retinaldehyde binding protein 1

chr5_+_117841839 1.106 ENSMUST00000142742.2
 Nos1
nitric oxide synthase 1, neuronal
chr15_-_66812593 1.051 ENSMUST00000100572.3
 Sla
src-like adaptor
chr10_-_64090241 1.037 ENSMUST00000133588.1
 Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr14_-_79301623 1.034 ENSMUST00000022595.7
 Rgcc
regulator of cell cycle
chr14_+_65968483 0.984 ENSMUST00000022616.6
 Clu
clusterin
chr2_-_166581969 0.958 ENSMUST00000109246.1
 Prex1
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
chr7_-_105482197 0.865 ENSMUST00000047040.2
 Prkcdbp
protein kinase C, delta binding protein
chr18_+_61045139 0.790 ENSMUST00000025522.4
ENSMUST00000115274.1
 Pdgfrb

platelet derived growth factor receptor, beta polypeptide

chr6_+_124996681 0.785 ENSMUST00000032479.4
 Pianp
PILR alpha associated neural protein
chr6_-_124769548 0.782 ENSMUST00000149652.1
ENSMUST00000112476.1
ENSMUST00000004378.8
 Eno2


enolase 2, gamma neuronal


chr9_-_20728219 0.747 ENSMUST00000034692.7
 Olfm2
olfactomedin 2
chr15_+_84669565 0.739 ENSMUST00000171460.1
 Prr5
proline rich 5 (renal)
chr13_-_54611274 0.725 ENSMUST00000049575.7
 Cltb
clathrin, light polypeptide (Lcb)
chr8_+_23035116 0.722 ENSMUST00000117296.1
ENSMUST00000141784.2
 Ank1

ankyrin 1, erythroid

chr13_-_54611332 0.707 ENSMUST00000091609.4
 Cltb
clathrin, light polypeptide (Lcb)
chr11_-_69369377 0.706 ENSMUST00000092971.6
ENSMUST00000108661.1
 Chd3

chromodomain helicase DNA binding protein 3

chr15_+_38933142 0.676 ENSMUST00000163313.1
 Baalc
brain and acute leukemia, cytoplasmic

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 354 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 2.3 GO:1902847 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of tau-protein kinase activity(GO:1902949)
0.0 1.7 GO:0034605 cellular response to heat(GO:0034605)
0.0 1.7 GO:0033014 porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014)
0.3 1.6 GO:0002024 diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845)
0.2 1.6 GO:1902993 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.2 1.4 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.0 1.4 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 1.3 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.3 1.2 GO:1901204 regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204)
0.0 1.1 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.2 1.0 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 1.0 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 1.0 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 1.0 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.3 0.9 GO:0043465 regulation of fermentation(GO:0043465) negative regulation of fermentation(GO:1901003)
0.2 0.9 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.1 0.9 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.1 0.9 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.3 0.8 GO:0035441 cell migration involved in vasculogenesis(GO:0035441) metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262)
0.1 0.8 GO:0046103 ADP biosynthetic process(GO:0006172) inosine biosynthetic process(GO:0046103)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 139 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 2.3 GO:0034366 spherical high-density lipoprotein particle(GO:0034366) neurofibrillary tangle(GO:0097418)
0.1 1.5 GO:0031430 M band(GO:0031430)
0.1 1.4 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.1 1.4 GO:0038201 TOR complex(GO:0038201)
0.1 1.1 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 1.1 GO:0005604 basement membrane(GO:0005604)
0.0 1.1 GO:0043198 dendritic shaft(GO:0043198)
0.0 1.0 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 1.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.9 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 0.8 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.8 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.7 GO:0032279 asymmetric synapse(GO:0032279)
0.1 0.6 GO:0005638 lamin filament(GO:0005638)
0.0 0.6 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.6 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.6 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.6 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.6 GO:0030686 90S preribosome(GO:0030686)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 227 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.5 GO:0051787 misfolded protein binding(GO:0051787)
0.0 1.6 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 1.6 GO:0070412 R-SMAD binding(GO:0070412)
0.0 1.6 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.6 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 1.5 GO:0030552 cAMP binding(GO:0030552)
0.2 1.4 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.4 1.3 GO:0004980 melanocortin receptor activity(GO:0004977) melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 1.3 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 1.3 GO:0005080 protein kinase C binding(GO:0005080)
0.0 1.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.4 1.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 1.1 GO:0019210 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.3 1.0 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.1 0.9 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.2 0.8 GO:0015186 L-asparagine transmembrane transporter activity(GO:0015182) L-glutamine transmembrane transporter activity(GO:0015186)
0.2 0.8 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 0.8 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)