Motif ID: Nfkb2

Z-value: 0.465


Transcription factors associated with Nfkb2:

Gene SymbolEntrez IDGene Name
Nfkb2 ENSMUSG00000025225.8 Nfkb2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nfkb2mm10_v2_chr19_+_46304709_463048110.106.6e-01Click!


Activity profile for motif Nfkb2.

activity profile for motif Nfkb2


Sorted Z-values histogram for motif Nfkb2

Sorted Z-values for motif Nfkb2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nfkb2

PNG image of the network

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Top targets:


Showing 1 to 20 of 62 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_74791516 1.846 ENSMUST00000006718.8
 Wnt10a
wingless related MMTV integration site 10a
chr13_-_111490111 0.921 ENSMUST00000047627.7
 Gpbp1
GC-rich promoter binding protein 1
chr13_-_111490028 0.857 ENSMUST00000091236.4
 Gpbp1
GC-rich promoter binding protein 1
chr8_+_108714644 0.764 ENSMUST00000043896.8
 Zfhx3
zinc finger homeobox 3
chr2_-_37422869 0.694 ENSMUST00000112936.1
ENSMUST00000112934.1
 Rc3h2

ring finger and CCCH-type zinc finger domains 2

chr11_+_77686155 0.682 ENSMUST00000100802.4
ENSMUST00000181023.1
 Nufip2

nuclear fragile X mental retardation protein interacting protein 2

chr11_-_84870712 0.658 ENSMUST00000170741.1
ENSMUST00000172405.1
ENSMUST00000100686.3
ENSMUST00000108081.2
 Ggnbp2



gametogenetin binding protein 2



chr11_-_84870646 0.645 ENSMUST00000018547.2
 Ggnbp2
gametogenetin binding protein 2
chr2_+_172550991 0.605 ENSMUST00000170744.1
 Tfap2c
transcription factor AP-2, gamma
chrX_+_163909132 0.533 ENSMUST00000033734.7
ENSMUST00000112294.2
 Ap1s2

adaptor-related protein complex 1, sigma 2 subunit

chr11_-_84870812 0.526 ENSMUST00000168434.1
 Ggnbp2
gametogenetin binding protein 2
chr3_-_116424007 0.494 ENSMUST00000090464.4
 Cdc14a
CDC14 cell division cycle 14A
chr10_+_59221945 0.493 ENSMUST00000182161.1
 Sowahc
sosondowah ankyrin repeat domain family member C
chr1_-_66817536 0.489 ENSMUST00000068168.3
ENSMUST00000113987.1
 Kansl1l

KAT8 regulatory NSL complex subunit 1-like

chr3_-_116423930 0.478 ENSMUST00000106491.2
 Cdc14a
CDC14 cell division cycle 14A
chr2_+_172550761 0.455 ENSMUST00000099058.3
 Tfap2c
transcription factor AP-2, gamma
chr4_-_125127817 0.445 ENSMUST00000036188.7
 Zc3h12a
zinc finger CCCH type containing 12A
chr11_-_84870188 0.397 ENSMUST00000154915.2
 Ggnbp2
gametogenetin binding protein 2
chr1_-_5019342 0.391 ENSMUST00000002533.8
 Rgs20
regulator of G-protein signaling 20
chr1_+_135132693 0.343 ENSMUST00000049449.4
 Ptpn7
protein tyrosine phosphatase, non-receptor type 7

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.8 GO:0048733 sebaceous gland development(GO:0048733)
0.4 1.1 GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598)
0.1 1.0 GO:0000022 mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
0.3 0.8 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.7 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 0.7 GO:0036465 synaptic vesicle recycling(GO:0036465)
0.1 0.4 GO:0045472 response to ether(GO:0045472) negative regulation of interleukin-1 beta secretion(GO:0050713) negative regulation of interferon-gamma secretion(GO:1902714) negative regulation of tumor necrosis factor secretion(GO:1904468)
0.1 0.4 GO:0070942 neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943)
0.1 0.4 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0 0.4 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.0 0.4 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.1 0.3 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.2 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.2 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.0 0.2 GO:0010225 response to UV-C(GO:0010225)
0.0 0.1 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 0.1 GO:0006680 glucosylceramide catabolic process(GO:0006680) negative regulation of filopodium assembly(GO:0051490)

Gene overrepresentation in cellular_component category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.7 GO:0042788 polysomal ribosome(GO:0042788)
0.1 0.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.4 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.4 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.4 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.4 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.2 GO:0031011 Ino80 complex(GO:0031011)

Gene overrepresentation in molecular_function category:

Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.8 GO:0005109 frizzled binding(GO:0005109)
0.0 1.1 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 1.0 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 0.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.4 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.4 GO:0030291 protein serine/threonine kinase inhibitor activity(GO:0030291)
0.0 0.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.2 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.1 GO:0070976 calcium-independent protein kinase C activity(GO:0004699) TIR domain binding(GO:0070976)