Motif ID: Tlx1

Z-value: 0.577


Transcription factors associated with Tlx1:

Gene SymbolEntrez IDGene Name
Tlx1 ENSMUSG00000025215.9 Tlx1



Activity profile for motif Tlx1.

activity profile for motif Tlx1


Sorted Z-values histogram for motif Tlx1

Sorted Z-values for motif Tlx1



Network of associatons between targets according to the STRING database.



First level regulatory network of Tlx1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_+_65265173 2.159 ENSMUST00000048762.1
 Cilp
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
chr11_+_97450136 1.923 ENSMUST00000107601.1
 Arhgap23
Rho GTPase activating protein 23
chr7_+_29309429 1.521 ENSMUST00000137848.1
 Dpf1
D4, zinc and double PHD fingers family 1
chr8_-_57962564 1.492 ENSMUST00000098757.3
 Galntl6
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6
chr2_+_13573927 1.339 ENSMUST00000141365.1
ENSMUST00000028062.2
 Vim

vimentin

chr8_-_109251698 1.289 ENSMUST00000079189.3
 4922502B01Rik
RIKEN cDNA 4922502B01 gene
chr1_-_75278345 1.276 ENSMUST00000039534.4
 Resp18
regulated endocrine-specific protein 18
chr2_-_26257554 1.271 ENSMUST00000137586.2
 C030048H21Rik
RIKEN cDNA C030048H21 gene
chr3_-_8667033 1.250 ENSMUST00000042412.3
 Hey1
hairy/enhancer-of-split related with YRPW motif 1
chr14_-_8309770 1.239 ENSMUST00000121887.1
ENSMUST00000036070.8
ENSMUST00000137133.1
 Fam107a


family with sequence similarity 107, member A


chr9_+_104566677 1.132 ENSMUST00000157006.1
 Cpne4
copine IV
chr1_+_153652943 1.116 ENSMUST00000041776.5
 Rgs8
regulator of G-protein signaling 8
chr12_-_112511136 1.114 ENSMUST00000066791.5
 Tmem179
transmembrane protein 179
chr10_+_86302854 1.095 ENSMUST00000132307.1
 Timp3
tissue inhibitor of metalloproteinase 3
chr5_-_100719675 1.052 ENSMUST00000112908.1
ENSMUST00000045617.8
 Hpse

heparanase

chr18_+_86711059 1.042 ENSMUST00000068423.3
 Cbln2
cerebellin 2 precursor protein
chr18_+_86711520 1.036 ENSMUST00000122464.1
 Cbln2
cerebellin 2 precursor protein
chr9_+_21165714 1.023 ENSMUST00000039413.8
 Pde4a
phosphodiesterase 4A, cAMP specific
chr9_+_76014855 0.986 ENSMUST00000008052.6
ENSMUST00000183425.1
ENSMUST00000183979.1
ENSMUST00000117981.2
 Hmgcll1



3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase-like 1



chr9_+_107400043 0.983 ENSMUST00000166799.1
ENSMUST00000170737.1
 Cacna2d2

calcium channel, voltage-dependent, alpha 2/delta subunit 2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 78 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 2.2 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 1.6 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.3 1.4 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.0 1.4 GO:0006198 cAMP catabolic process(GO:0006198)
0.3 1.3 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.3 1.3 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.4 1.1 GO:0030167 proteoglycan catabolic process(GO:0030167)
0.3 1.1 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.1 1.1 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.2 1.0 GO:0046950 cellular ketone body metabolic process(GO:0046950)
0.0 1.0 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 0.9 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.1 0.8 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.2 0.7 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.1 0.7 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1 0.7 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.1 0.7 GO:0044351 macropinocytosis(GO:0044351)
0.0 0.7 GO:0006491 N-glycan processing(GO:0006491)
0.2 0.6 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.1 0.6 GO:0044027 hypermethylation of CpG island(GO:0044027)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 38 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.5 GO:0071565 nBAF complex(GO:0071565)
0.0 1.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.3 1.3 GO:0045098 type III intermediate filament(GO:0045098)
0.3 1.3 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 1.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.8 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.7 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 0.7 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.7 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 0.6 GO:0000243 commitment complex(GO:0000243)
0.0 0.6 GO:0001741 XY body(GO:0001741)
0.0 0.6 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.6 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.6 GO:0031901 early endosome membrane(GO:0031901)
0.1 0.5 GO:0098536 deuterosome(GO:0098536)
0.0 0.4 GO:0033269 internode region of axon(GO:0033269)
0.0 0.4 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.3 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.3 GO:0008278 cohesin complex(GO:0008278)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 50 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.6 GO:0035496 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980) O antigen polymerase activity(GO:0008755) lipopolysaccharide-1,6-galactosyltransferase activity(GO:0008921) cellulose synthase activity(GO:0016759) 9-phenanthrol UDP-glucuronosyltransferase activity(GO:0018715) 1-phenanthrol glycosyltransferase activity(GO:0018716) 9-phenanthrol glycosyltransferase activity(GO:0018717) 1,2-dihydroxy-phenanthrene glycosyltransferase activity(GO:0018718) phenanthrol glycosyltransferase activity(GO:0019112) alpha-1,2-galactosyltransferase activity(GO:0031278) dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0033556) endogalactosaminidase activity(GO:0033931) lipopolysaccharide-1,5-galactosyltransferase activity(GO:0035496) dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0042283) inositol phosphoceramide synthase activity(GO:0045140) alpha-(1->3)-fucosyltransferase activity(GO:0046920) indole-3-butyrate beta-glucosyltransferase activity(GO:0052638) salicylic acid glucosyltransferase (ester-forming) activity(GO:0052639) salicylic acid glucosyltransferase (glucoside-forming) activity(GO:0052640) benzoic acid glucosyltransferase activity(GO:0052641) chondroitin hydrolase activity(GO:0052757) dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity(GO:0052824) cytokinin 9-beta-glucosyltransferase activity(GO:0080062)
0.0 1.4 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.4 1.3 GO:0035939 microsatellite binding(GO:0035939)
0.3 1.3 GO:1990254 keratin filament binding(GO:1990254)
0.4 1.1 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 1.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.2 1.0 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 1.0 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 1.0 GO:0030552 cAMP binding(GO:0030552)
0.0 0.8 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.8 GO:0017049 GTP-Rho binding(GO:0017049)
0.2 0.7 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.1 0.7 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.7 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.7 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.7 GO:0008748 N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) epoxyqueuosine reductase activity(GO:0052693)
0.1 0.6 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 0.6 GO:0051718 DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.0 0.6 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.6 GO:0017069 snRNA binding(GO:0017069)