Motif ID: Pgr_Nr3c1

Z-value: 0.621

Transcription factors associated with Pgr_Nr3c1:

Gene SymbolEntrez IDGene Name
Nr3c1 ENSMUSG00000024431.8 Nr3c1
Pgr ENSMUSG00000031870.10 Pgr

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr3c1mm10_v2_chr18_-_39489880_394899150.666.6e-04Click!


Activity profile for motif Pgr_Nr3c1.

activity profile for motif Pgr_Nr3c1


Sorted Z-values histogram for motif Pgr_Nr3c1

Sorted Z-values for motif Pgr_Nr3c1



Network of associatons between targets according to the STRING database.



First level regulatory network of Pgr_Nr3c1

PNG image of the network

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Top targets:


Showing 1 to 20 of 126 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_+_20665250 8.565 ENSMUST00000075312.3
 Ttr
transthyretin
chr13_-_84064772 4.190 ENSMUST00000182477.1
 Gm17750
predicted gene, 17750
chr9_-_79718631 2.133 ENSMUST00000180083.1
 Col12a1
collagen, type XII, alpha 1
chr9_-_79718518 1.964 ENSMUST00000071750.6
 Col12a1
collagen, type XII, alpha 1
chr9_-_79718720 1.813 ENSMUST00000121227.1
 Col12a1
collagen, type XII, alpha 1
chr5_+_24364804 1.620 ENSMUST00000030834.4
ENSMUST00000115090.1
 Nos3

nitric oxide synthase 3, endothelial cell

chr18_-_62756275 1.156 ENSMUST00000067450.1
ENSMUST00000048109.5
 2700046A07Rik

RIKEN cDNA 2700046A07 gene

chr4_-_53159885 1.144 ENSMUST00000030010.3
 Abca1
ATP-binding cassette, sub-family A (ABC1), member 1
chr10_+_97565436 1.113 ENSMUST00000038160.4
 Lum
lumican
chr5_-_104114088 1.046 ENSMUST00000031249.3
 Sparcl1
SPARC-like 1
chr5_-_123140135 1.045 ENSMUST00000160099.1
 AI480526
expressed sequence AI480526
chr16_+_43363855 0.954 ENSMUST00000156367.1
 Zbtb20
zinc finger and BTB domain containing 20
chr14_-_16575456 0.841 ENSMUST00000063750.6
 Rarb
retinoic acid receptor, beta
chr2_-_63184253 0.837 ENSMUST00000075052.3
ENSMUST00000112454.1
 Kcnh7

potassium voltage-gated channel, subfamily H (eag-related), member 7

chr14_+_99298652 0.808 ENSMUST00000005279.6
 Klf5
Kruppel-like factor 5
chr13_+_29016267 0.789 ENSMUST00000140415.1
 A330102I10Rik
RIKEN cDNA A330102I10 gene
chr4_-_136898803 0.786 ENSMUST00000046285.5
 C1qa
complement component 1, q subcomponent, alpha polypeptide
chr16_-_5222257 0.691 ENSMUST00000050160.4
 AU021092
expressed sequence AU021092
chr2_+_91256144 0.607 ENSMUST00000154959.1
ENSMUST00000059566.4
 Pacsin3

protein kinase C and casein kinase substrate in neurons 3

chr3_-_152193803 0.588 ENSMUST00000050073.6
 Dnajb4
DnaJ (Hsp40) homolog, subfamily B, member 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 38 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.7 8.6 GO:0070327 thyroid hormone transport(GO:0070327)
0.5 1.6 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100) regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.3 1.1 GO:0055099 regulation of Cdc42 protein signal transduction(GO:0032489) response to high density lipoprotein particle(GO:0055099) platelet dense granule organization(GO:0060155)
0.3 1.1 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0 1.0 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.9 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.8 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 0.8 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.8 GO:0006958 complement activation, classical pathway(GO:0006958)
0.2 0.5 GO:0006601 creatine biosynthetic process(GO:0006601)
0.2 0.5 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.1 0.5 GO:0016081 synaptic vesicle docking(GO:0016081)
0.0 0.5 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.0 0.4 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0 0.4 GO:0051642 centrosome localization(GO:0051642)
0.1 0.3 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.0 0.3 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.3 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 0.2 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.2 GO:0038018 Wnt receptor catabolic process(GO:0038018)

Gene overrepresentation in cellular_component category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.0 5.9 GO:0005595 collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934)
0.0 1.5 GO:0005901 caveola(GO:0005901)
0.0 1.2 GO:0005581 collagen trimer(GO:0005581)
0.1 1.1 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 1.1 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 0.3 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.2 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.1 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 0.1 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 25 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 8.6 GO:0070324 thyroid hormone binding(GO:0070324)
0.5 1.6 GO:0004517 nitric-oxide synthase activity(GO:0004517) arginine binding(GO:0034618)
0.1 1.5 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.4 1.1 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188)
0.0 1.1 GO:0005518 collagen binding(GO:0005518)
0.1 1.0 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.9 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.8 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 0.5 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.5 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.5 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.1 0.4 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.4 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.4 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 0.3 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.0 0.3 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.2 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.2 GO:0005212 structural constituent of eye lens(GO:0005212)