Motif ID: Mnt

Z-value: 0.718


Transcription factors associated with Mnt:

Gene SymbolEntrez IDGene Name
Mnt ENSMUSG00000000282.6 Mnt

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mntmm10_v2_chr11_+_74830920_74831005-0.282.0e-01Click!


Activity profile for motif Mnt.

activity profile for motif Mnt


Sorted Z-values histogram for motif Mnt

Sorted Z-values for motif Mnt



Network of associatons between targets according to the STRING database.



First level regulatory network of Mnt

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_-_25570678 3.646 ENSMUST00000025003.3
ENSMUST00000173447.1
 Sox8

SRY-box containing gene 8

chr1_-_186705980 3.361 ENSMUST00000045288.8
 Tgfb2
transforming growth factor, beta 2
chr15_+_81811414 3.165 ENSMUST00000023024.7
 Tef
thyrotroph embryonic factor
chr8_-_29219338 2.695 ENSMUST00000168630.2
 Unc5d
unc-5 homolog D (C. elegans)
chr12_+_70825492 2.675 ENSMUST00000057859.7
 Frmd6
FERM domain containing 6
chr4_-_53159885 2.368 ENSMUST00000030010.3
 Abca1
ATP-binding cassette, sub-family A (ABC1), member 1
chr2_+_4300462 2.244 ENSMUST00000175669.1
 Frmd4a
FERM domain containing 4A
chr15_+_57694651 2.136 ENSMUST00000096430.4
 Zhx2
zinc fingers and homeoboxes 2
chr8_+_40862379 2.117 ENSMUST00000098816.3
ENSMUST00000057784.8
ENSMUST00000141505.1
 Slc7a2


solute carrier family 7 (cationic amino acid transporter, y+ system), member 2


chr10_+_57794335 2.044 ENSMUST00000151623.1
ENSMUST00000020022.7
 Smpdl3a

sphingomyelin phosphodiesterase, acid-like 3A

chr16_-_43979050 2.010 ENSMUST00000165648.1
ENSMUST00000036321.7
 Zdhhc23

zinc finger, DHHC domain containing 23

chr6_+_17463749 1.966 ENSMUST00000115443.1
 Met
met proto-oncogene
chr11_-_101785252 1.954 ENSMUST00000164750.1
ENSMUST00000107176.1
ENSMUST00000017868.6
 Etv4


ets variant gene 4 (E1A enhancer binding protein, E1AF)


chr1_-_119422239 1.879 ENSMUST00000038765.5
 Inhbb
inhibin beta-B
chr14_-_18239053 1.749 ENSMUST00000090543.5
 Nr1d2
nuclear receptor subfamily 1, group D, member 2
chr12_-_90738438 1.745 ENSMUST00000082432.3
 Dio2
deiodinase, iodothyronine, type II
chr17_-_66077022 1.629 ENSMUST00000150766.1
ENSMUST00000038116.5
 Ankrd12

ankyrin repeat domain 12

chr6_+_17463927 1.583 ENSMUST00000115442.1
 Met
met proto-oncogene
chr13_+_38345716 1.558 ENSMUST00000171970.1
 Bmp6
bone morphogenetic protein 6
chrX_-_51681703 1.528 ENSMUST00000088172.5
 Hs6st2
heparan sulfate 6-O-sulfotransferase 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 246 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 4.6 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
1.2 3.6 GO:0072034 renal vesicle induction(GO:0072034)
1.1 3.4 GO:0048818 positive regulation of hair follicle maturation(GO:0048818) positive regulation of catagen(GO:0051795) regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905005)
0.2 3.1 GO:0021859 pyramidal neuron differentiation(GO:0021859)
0.9 2.7 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
0.4 2.7 GO:0003383 apical constriction(GO:0003383)
0.6 2.4 GO:0055099 regulation of Cdc42 protein signal transduction(GO:0032489) response to high density lipoprotein particle(GO:0055099) platelet dense granule organization(GO:0060155)
0.3 2.3 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.4 2.2 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460)
0.1 2.2 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.1 2.2 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.7 2.1 GO:1904049 regulation of spontaneous neurotransmitter secretion(GO:1904048) negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.4 2.1 GO:0090467 lysine transport(GO:0015819) L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
0.3 2.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.3 2.0 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600) regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.6 1.9 GO:0046881 positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.3 1.9 GO:0000050 urea cycle(GO:0000050) urea metabolic process(GO:0019627)
0.3 1.9 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.3 1.6 GO:0032346 positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349)
0.1 1.6 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 103 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.7 GO:0009925 basal plasma membrane(GO:0009925)
0.0 3.1 GO:0005604 basement membrane(GO:0005604)
0.0 2.4 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 2.3 GO:0090544 BAF-type complex(GO:0090544)
0.4 2.1 GO:1990761 growth cone lamellipodium(GO:1990761)
0.1 2.0 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.5 1.9 GO:0043511 inhibin complex(GO:0043511)
0.1 1.9 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 1.8 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 1.6 GO:0000922 spindle pole(GO:0000922)
0.1 1.5 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 1.5 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.1 1.3 GO:0070852 cell body fiber(GO:0070852)
0.0 1.3 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 1.3 GO:0034399 nuclear periphery(GO:0034399)
0.4 1.2 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.3 1.2 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.3 1.2 GO:1990795 lateral part of cell(GO:0097574) basolateral part of cell(GO:1990794) rod bipolar cell terminal bouton(GO:1990795)
0.2 1.2 GO:0070695 FHF complex(GO:0070695)
0.1 1.2 GO:0042405 nuclear inclusion body(GO:0042405)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 152 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 4.6 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.1 3.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.8 3.4 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 2.8 GO:0015485 cholesterol binding(GO:0015485)
0.1 2.5 GO:0034945 dihydrolipoamide branched chain acyltransferase activity(GO:0004147) palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity(GO:0008951) serine O-acyltransferase activity(GO:0016412) O-succinyltransferase activity(GO:0016750) sinapoyltransferase activity(GO:0016752) O-sinapoyltransferase activity(GO:0016753) peptidyl-lysine N6-myristoyltransferase activity(GO:0018030) peptidyl-lysine N6-palmitoyltransferase activity(GO:0018031) benzoyl acetate-CoA thiolase activity(GO:0018711) 3-hydroxybutyryl-CoA thiolase activity(GO:0018712) 3-ketopimelyl-CoA thiolase activity(GO:0018713) N-palmitoyltransferase activity(GO:0019105) acyl-CoA N-acyltransferase activity(GO:0019186) protein-cysteine S-myristoyltransferase activity(GO:0019705) glucosaminyl-phosphotidylinositol O-acyltransferase activity(GO:0032216) ergosterol O-acyltransferase activity(GO:0034737) lanosterol O-acyltransferase activity(GO:0034738) naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity(GO:0034848) 2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity(GO:0034851) 2-methylhexanoyl-CoA C-acetyltransferase activity(GO:0034915) butyryl-CoA 2-C-propionyltransferase activity(GO:0034919) 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity(GO:0034945) L-2-aminoadipate N-acetyltransferase activity(GO:0043741) keto acid formate lyase activity(GO:0043806) azetidine-2-carboxylic acid acetyltransferase activity(GO:0046941) peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0052858) acetyl-CoA:L-lysine N6-acetyltransferase(GO:0090595)
0.8 2.4 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188)
0.1 2.4 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.2 2.2 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.0 2.2 GO:0030674 protein binding, bridging(GO:0030674)
0.3 2.1 GO:0015189 L-ornithine transmembrane transporter activity(GO:0000064) arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189)
0.3 2.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 2.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 2.0 GO:0045502 dynein binding(GO:0045502)
0.0 2.0 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.2 1.9 GO:0034711 inhibin binding(GO:0034711)
0.3 1.7 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.2 1.7 GO:0103116 alpha-D-galactofuranose transporter activity(GO:0103116)
0.1 1.7 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 1.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.2 1.6 GO:0070700 BMP receptor binding(GO:0070700)