Motif ID: Ets2

Z-value: 0.884


Transcription factors associated with Ets2:

Gene SymbolEntrez IDGene Name
Ets2 ENSMUSG00000022895.8 Ets2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ets2mm10_v2_chr16_+_95702044_957020940.482.0e-02Click!


Activity profile for motif Ets2.

activity profile for motif Ets2


Sorted Z-values histogram for motif Ets2

Sorted Z-values for motif Ets2



Network of associatons between targets according to the STRING database.



First level regulatory network of Ets2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_55419898 3.292 ENSMUST00000108858.1
ENSMUST00000141530.1
 Sparc

secreted acidic cysteine rich glycoprotein

chr1_-_56969864 2.738 ENSMUST00000177424.1
 Satb2
special AT-rich sequence binding protein 2
chr5_+_111733924 2.672 ENSMUST00000180627.1
 Gm26897
predicted gene, 26897
chr17_+_3397189 2.588 ENSMUST00000072156.6
 Tiam2
T cell lymphoma invasion and metastasis 2
chr1_-_56969827 2.438 ENSMUST00000176759.1
 Satb2
special AT-rich sequence binding protein 2
chr6_+_5725639 2.357 ENSMUST00000115556.1
ENSMUST00000115555.1
ENSMUST00000115559.3
 Dync1i1


dynein cytoplasmic 1 intermediate chain 1


chr5_-_99252839 2.122 ENSMUST00000168092.1
ENSMUST00000031276.8
 Rasgef1b

RasGEF domain family, member 1B

chr6_+_5725812 1.962 ENSMUST00000115554.1
ENSMUST00000153942.1
 Dync1i1

dynein cytoplasmic 1 intermediate chain 1

chr3_-_87768932 1.810 ENSMUST00000173184.1
ENSMUST00000172621.1
ENSMUST00000174759.1
ENSMUST00000172590.1
ENSMUST00000079083.5
 Pear1




platelet endothelial aggregation receptor 1




chr3_-_80802789 1.798 ENSMUST00000107745.1
ENSMUST00000075316.4
 Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr4_-_32950813 1.776 ENSMUST00000084750.1
ENSMUST00000084748.2
 Ankrd6

ankyrin repeat domain 6

chr1_+_16688405 1.659 ENSMUST00000026881.4
 Ly96
lymphocyte antigen 96
chr9_-_103219823 1.608 ENSMUST00000168142.1
 Trf
transferrin
chr3_+_94933041 1.600 ENSMUST00000090839.5
 Selenbp1
selenium binding protein 1
chr14_-_18239053 1.590 ENSMUST00000090543.5
 Nr1d2
nuclear receptor subfamily 1, group D, member 2
chr12_+_83688123 1.533 ENSMUST00000041806.5
 Psen1
presenilin 1
chr10_-_53379816 1.529 ENSMUST00000095691.5
 Cep85l
centrosomal protein 85-like
chr15_-_43869993 1.475 ENSMUST00000067469.4
 Tmem74
transmembrane protein 74
chr4_+_128058962 1.474 ENSMUST00000184063.1
 Csmd2
CUB and Sushi multiple domains 2
chr1_-_135688094 1.464 ENSMUST00000112103.1
 Nav1
neuron navigator 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 172 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 5.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 5.0 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.1 4.4 GO:0047496 vesicle transport along microtubule(GO:0047496)
0.1 3.3 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.1 2.7 GO:0050873 brown fat cell differentiation(GO:0050873)
0.1 2.2 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.0 2.2 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.1 1.9 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.5 1.8 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.1 1.8 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 1.8 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 1.8 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.4 1.7 GO:0034135 regulation of toll-like receptor 2 signaling pathway(GO:0034135)
0.3 1.7 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.3 1.6 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.5 1.5 GO:0003032 detection of oxygen(GO:0003032)
0.3 1.5 GO:0015871 choline transport(GO:0015871) regulation of resting membrane potential(GO:0060075)
0.0 1.5 GO:0001578 microtubule bundle formation(GO:0001578)
0.5 1.4 GO:0019085 early viral transcription(GO:0019085)
0.1 1.4 GO:2000505 regulation of energy homeostasis(GO:2000505)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 80 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.8 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 3.9 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.8 3.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 2.7 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 2.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.3 2.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 2.1 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 2.1 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.2 1.8 GO:0001739 sex chromatin(GO:0001739)
0.1 1.8 GO:0032279 asymmetric synapse(GO:0032279)
0.3 1.7 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.2 1.6 GO:0097433 dense body(GO:0097433)
0.1 1.6 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.5 1.5 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 1.5 GO:0001891 phagocytic cup(GO:0001891)
0.0 1.5 GO:0031201 SNARE complex(GO:0031201)
0.1 1.4 GO:0032584 growth cone membrane(GO:0032584)
0.2 1.3 GO:0034366 spherical high-density lipoprotein particle(GO:0034366) neurofibrillary tangle(GO:0097418)
0.1 1.3 GO:0005605 basal lamina(GO:0005605)
0.3 1.2 GO:0043020 NADPH oxidase complex(GO:0043020)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 108 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 5.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.9 4.3 GO:0045503 dynein light chain binding(GO:0045503)
0.0 3.2 GO:0008013 beta-catenin binding(GO:0008013)
0.1 3.1 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 2.8 GO:0017137 Rab GTPase binding(GO:0017137)
0.2 2.7 GO:0008430 selenium binding(GO:0008430)
0.1 2.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 2.1 GO:0030276 clathrin binding(GO:0030276)
0.3 1.8 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 1.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.6 1.7 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 1.7 GO:0051787 misfolded protein binding(GO:0051787)
0.3 1.6 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.2 1.6 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1 1.6 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 1.6 GO:0045296 cadherin binding(GO:0045296)
0.5 1.5 GO:0005534 galactose binding(GO:0005534)
0.2 1.5 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 1.4 GO:0008083 growth factor activity(GO:0008083)
0.0 1.4 GO:0017124 SH3 domain binding(GO:0017124)