Motif ID: Hoxd1

Z-value: 0.865


Transcription factors associated with Hoxd1:

Gene SymbolEntrez IDGene Name
Hoxd1 ENSMUSG00000042448.4 Hoxd1



Activity profile for motif Hoxd1.

activity profile for motif Hoxd1


Sorted Z-values histogram for motif Hoxd1

Sorted Z-values for motif Hoxd1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxd1

PNG image of the network

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Top targets:


Showing 1 to 20 of 155 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_8710734 2.945 ENSMUST00000005493.7
 Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr3_-_85722474 2.844 ENSMUST00000119077.1
 Fam160a1
family with sequence similarity 160, member A1
chr15_-_8710409 2.656 ENSMUST00000157065.1
 Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr2_+_116067213 2.511 ENSMUST00000152412.1
 G630016G05Rik
RIKEN cDNA G630016G05 gene
chr2_+_150323702 2.151 ENSMUST00000133235.2
 Gm10130
predicted gene 10130
chr2_-_20943413 1.990 ENSMUST00000140230.1
 Arhgap21
Rho GTPase activating protein 21
chr5_+_134932351 1.978 ENSMUST00000047196.7
ENSMUST00000111221.2
ENSMUST00000111219.1
ENSMUST00000068617.5
ENSMUST00000111218.1
ENSMUST00000136246.1
 Wbscr27





Williams Beuren syndrome chromosome region 27 (human)





chr17_-_45659312 1.962 ENSMUST00000120717.1
 Capn11
calpain 11
chr5_-_62766153 1.934 ENSMUST00000076623.4
 Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr17_-_36032682 1.788 ENSMUST00000102678.4
 H2-T23
histocompatibility 2, T region locus 23
chr2_-_116067391 1.766 ENSMUST00000140185.1
 2700033N17Rik
RIKEN cDNA 2700033N17 gene
chr17_+_88440711 1.639 ENSMUST00000112238.2
ENSMUST00000155640.1
 Foxn2

forkhead box N2

chr13_-_105054895 1.568 ENSMUST00000063551.5
 Rgs7bp
regulator of G-protein signalling 7 binding protein
chr2_+_109917639 1.492 ENSMUST00000046548.7
ENSMUST00000111037.2
 Lgr4

leucine-rich repeat-containing G protein-coupled receptor 4

chr5_+_107497762 1.471 ENSMUST00000152474.1
ENSMUST00000060553.7
 A830010M20Rik

RIKEN cDNA A830010M20 gene

chr2_+_170731807 1.469 ENSMUST00000029075.4
 Dok5
docking protein 5
chr6_+_149582012 1.426 ENSMUST00000144085.2
 Gm21814
predicted gene, 21814
chr15_+_98571004 1.378 ENSMUST00000023728.6
 4930415O20Rik
RIKEN cDNA 4930415O20 gene
chr3_-_116712644 1.324 ENSMUST00000029569.2
 Slc35a3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chr11_+_35121126 1.268 ENSMUST00000069837.3
 Slit3
slit homolog 3 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 60 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.4 5.6 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.4 2.0 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 1.9 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.6 1.8 GO:2000564 CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.0 1.6 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.5 1.5 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.1 1.5 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.3 1.3 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.2 1.3 GO:0070100 negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.0 1.2 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.3 1.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 1.1 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.1 1.1 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 1.1 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 1.1 GO:0035082 axoneme assembly(GO:0035082)
0.1 1.0 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 0.9 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.2 0.8 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.2 0.8 GO:0021993 initiation of neural tube closure(GO:0021993)
0.1 0.8 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 5.6 GO:0043205 fibril(GO:0043205)
0.0 2.3 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 1.8 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 1.2 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.2 1.1 GO:0002177 manchette(GO:0002177)
0.1 1.1 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 1.1 GO:0005776 autophagosome(GO:0005776)
0.0 0.9 GO:0016459 myosin complex(GO:0016459)
0.0 0.8 GO:0031519 PcG protein complex(GO:0031519)
0.1 0.7 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.7 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.7 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.6 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.2 0.5 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 0.4 GO:0008623 CHRAC(GO:0008623)
0.1 0.4 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.4 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 0.3 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.3 GO:0071439 clathrin complex(GO:0071439)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 46 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 5.6 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.1 2.0 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 1.9 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.2 1.8 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 1.8 GO:0005158 insulin receptor binding(GO:0005158)
0.1 1.5 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 1.5 GO:0017161 phosphohistidine phosphatase activity(GO:0008969) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) NADP phosphatase activity(GO:0019178) 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity(GO:0043726) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052867) IDP phosphatase activity(GO:1990003)
0.1 1.4 GO:0005402 cation:sugar symporter activity(GO:0005402)
0.2 1.3 GO:0048495 Roundabout binding(GO:0048495)
0.1 1.2 GO:0050811 GABA-A receptor activity(GO:0004890) GABA receptor binding(GO:0050811)
0.1 1.1 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 1.1 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 1.0 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.9 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.9 GO:0030507 spectrin binding(GO:0030507)
0.0 0.8 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.2 0.7 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.2 0.7 GO:0051378 primary amine oxidase activity(GO:0008131) serotonin binding(GO:0051378)
0.2 0.7 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)