Motif ID: Chd1_Pml

Z-value: 2.911

Transcription factors associated with Chd1_Pml:

Gene SymbolEntrez IDGene Name
Chd1 ENSMUSG00000023852.7 Chd1
Pml ENSMUSG00000036986.10 Pml

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Chd1mm10_v2_chr17_+_15704963_157049940.721.1e-04Click!
Pmlmm10_v2_chr9_-_58249702_58249791-0.378.2e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Chd1_Pml

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_-_106458440 16.489 ENSMUST00000086795.6
Barhl2
BarH-like 2 (Drosophila)
chr5_+_139543889 15.603 ENSMUST00000174792.1
ENSMUST00000031523.8
Uncx

UNC homeobox

chr2_-_34372004 15.121 ENSMUST00000113132.2
ENSMUST00000040638.8
Pbx3

pre B cell leukemia homeobox 3

chr4_+_62965560 10.788 ENSMUST00000030043.6
ENSMUST00000107415.1
ENSMUST00000064814.5
Zfp618


zinc finger protein 618


chr6_-_39206782 9.459 ENSMUST00000002305.8
Jhdm1d
jumonji C domain-containing histone demethylase 1 homolog D (S. cerevisiae)
chr7_-_137314394 9.005 ENSMUST00000168203.1
ENSMUST00000106118.2
ENSMUST00000169486.2
ENSMUST00000033378.5
Ebf3



early B cell factor 3



chr10_-_120476469 8.417 ENSMUST00000072777.7
ENSMUST00000159699.1
Hmga2

high mobility group AT-hook 2

chr13_-_107890059 8.216 ENSMUST00000105097.2
Zswim6
zinc finger SWIM-type containing 6
chr16_-_22163299 7.992 ENSMUST00000100052.4
Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
chr16_+_81200697 7.850 ENSMUST00000067602.3
ENSMUST00000037785.7
Ncam2

neural cell adhesion molecule 2

chr8_-_116732991 7.788 ENSMUST00000109102.2
Cdyl2
chromodomain protein, Y chromosome-like 2
chr14_-_98169542 7.764 ENSMUST00000069334.7
ENSMUST00000071533.6
Dach1

dachshund 1 (Drosophila)

chr1_+_167001417 7.762 ENSMUST00000165874.1
Fam78b
family with sequence similarity 78, member B
chr1_+_167001457 7.473 ENSMUST00000126198.1
Fam78b
family with sequence similarity 78, member B
chr14_+_122475397 7.416 ENSMUST00000075888.5
Zic2
zinc finger protein of the cerebellum 2
chr3_-_8667033 7.243 ENSMUST00000042412.3
Hey1
hairy/enhancer-of-split related with YRPW motif 1
chr9_+_107399858 7.196 ENSMUST00000085092.5
ENSMUST00000164988.2
Cacna2d2

calcium channel, voltage-dependent, alpha 2/delta subunit 2

chr12_+_3807076 6.701 ENSMUST00000174817.1
Dnmt3a
DNA methyltransferase 3A
chr9_+_107400043 6.438 ENSMUST00000166799.1
ENSMUST00000170737.1
Cacna2d2

calcium channel, voltage-dependent, alpha 2/delta subunit 2

chr7_-_74554474 6.245 ENSMUST00000134539.1
ENSMUST00000026897.7
ENSMUST00000098371.2
Slco3a1


solute carrier organic anion transporter family, member 3a1



Gene overrepresentation in biological_process category:

Showing 1 to 20 of 1,032 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.5 21.4 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.1 19.9 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
1.3 19.4 GO:0035563 positive regulation of chromatin binding(GO:0035563)
2.8 16.6 GO:0060024 rhythmic synaptic transmission(GO:0060024)
1.7 15.0 GO:0046499 S-adenosylmethioninamine metabolic process(GO:0046499)
1.8 14.1 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
1.4 12.7 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.9 11.8 GO:0015732 prostaglandin transport(GO:0015732)
2.9 11.4 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.9 11.4 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
3.7 11.1 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
2.2 10.9 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.6 10.1 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
1.3 10.0 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.5 10.0 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
1.0 9.9 GO:0008063 Toll signaling pathway(GO:0008063)
0.7 9.5 GO:0061000 negative regulation of dendritic spine development(GO:0061000)
0.6 9.5 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.3 9.3 GO:0001709 cell fate determination(GO:0001709)
2.3 9.2 GO:0044861 protein transport into plasma membrane raft(GO:0044861)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 339 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 227.6 GO:0005634 nucleus(GO:0005634)
0.6 24.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 24.2 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.8 18.9 GO:0001741 XY body(GO:0001741)
0.3 16.7 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.3 14.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.3 14.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 14.4 GO:0005874 microtubule(GO:0005874)
0.2 13.5 GO:0016605 PML body(GO:0016605)
0.7 13.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.8 13.0 GO:0097470 ribbon synapse(GO:0097470)
0.1 12.1 GO:0005681 spliceosomal complex(GO:0005681)
3.8 11.4 GO:0042642 actomyosin, myosin complex part(GO:0042642)
0.2 11.4 GO:0005814 centriole(GO:0005814)
1.0 11.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 11.1 GO:0016604 nuclear body(GO:0016604)
0.1 10.8 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.3 10.7 GO:0090544 BAF-type complex(GO:0090544)
0.2 10.7 GO:0005844 polysome(GO:0005844)
0.6 9.9 GO:0030014 CCR4-NOT complex(GO:0030014)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 524 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 46.8 GO:0044822 poly(A) RNA binding(GO:0044822)
0.2 44.1 GO:0043774 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738)
0.2 29.3 GO:0008017 microtubule binding(GO:0008017)
1.1 28.6 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.6 26.7 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.2 24.3 GO:0061659 ubiquitin-like protein ligase activity(GO:0061659)
0.1 23.6 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.3 23.3 GO:0035064 methylated histone binding(GO:0035064)
0.4 21.7 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.2 17.2 GO:0042393 histone binding(GO:0042393)
0.4 15.1 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
1.9 15.0 GO:0051718 DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.1 13.5 GO:0003714 transcription corepressor activity(GO:0003714)
1.4 12.6 GO:0001972 retinoic acid binding(GO:0001972)
1.2 12.4 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.3 12.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 12.2 GO:0017137 Rab GTPase binding(GO:0017137)
1.3 12.1 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.6 12.0 GO:0070577 lysine-acetylated histone binding(GO:0070577)
1.5 11.8 GO:0046790 virion binding(GO:0046790)