Motif ID: Nr2e3

Z-value: 0.645


Transcription factors associated with Nr2e3:

Gene SymbolEntrez IDGene Name
Nr2e3 ENSMUSG00000032292.2 Nr2e3



Activity profile for motif Nr2e3.

activity profile for motif Nr2e3


Sorted Z-values histogram for motif Nr2e3

Sorted Z-values for motif Nr2e3



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr2e3

PNG image of the network

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Top targets:


Showing 1 to 20 of 163 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_+_43510267 1.382 ENSMUST00000114695.2
 Zbtb20
zinc finger and BTB domain containing 20
chr16_+_43508118 1.300 ENSMUST00000114690.1
 Zbtb20
zinc finger and BTB domain containing 20
chr18_-_35215008 1.272 ENSMUST00000091636.3
 Lrrtm2
leucine rich repeat transmembrane neuronal 2
chr17_+_75178797 1.165 ENSMUST00000112516.1
ENSMUST00000135447.1
 Ltbp1

latent transforming growth factor beta binding protein 1

chr17_+_75178911 1.078 ENSMUST00000112514.1
 Ltbp1
latent transforming growth factor beta binding protein 1
chr14_+_101840602 0.886 ENSMUST00000159314.1
 Lmo7
LIM domain only 7
chr1_-_58424042 0.875 ENSMUST00000034868.7
 Clk1
CDC-like kinase 1
chr14_+_101840501 0.814 ENSMUST00000159026.1
 Lmo7
LIM domain only 7
chr1_+_19103022 0.793 ENSMUST00000037294.7
 Tfap2d
transcription factor AP-2, delta
chr2_-_140671440 0.789 ENSMUST00000099301.1
 Flrt3
fibronectin leucine rich transmembrane protein 3
chr3_+_54156039 0.770 ENSMUST00000029311.6
 Trpc4
transient receptor potential cation channel, subfamily C, member 4
chr2_-_140671462 0.768 ENSMUST00000110057.2
 Flrt3
fibronectin leucine rich transmembrane protein 3
chr12_+_69963452 0.753 ENSMUST00000110560.1
 Gm3086
predicted gene 3086
chr2_-_45112890 0.719 ENSMUST00000076836.6
 Zeb2
zinc finger E-box binding homeobox 2
chr12_-_34528844 0.687 ENSMUST00000110819.2
 Hdac9
histone deacetylase 9
chr14_+_123659971 0.687 ENSMUST00000049681.7
 Itgbl1
integrin, beta-like 1
chr8_-_13200576 0.686 ENSMUST00000165605.2
 Grtp1
GH regulated TBC protein 1
chr11_-_102579461 0.683 ENSMUST00000107081.1
 Gm11627
predicted gene 11627
chr4_-_151861762 0.672 ENSMUST00000097774.2
 Camta1
calmodulin binding transcription activator 1
chr2_-_140671400 0.667 ENSMUST00000056760.3
 Flrt3
fibronectin leucine rich transmembrane protein 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 58 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.7 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.7 2.2 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
0.1 2.2 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.2 1.1 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 1.1 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 1.0 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.1 0.9 GO:2000809 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) positive regulation of synaptic vesicle clustering(GO:2000809)
0.1 0.9 GO:0030035 microspike assembly(GO:0030035)
0.0 0.8 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.0 0.8 GO:0030901 midbrain development(GO:0030901)
0.1 0.7 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.1 0.7 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.1 0.7 GO:0034983 peptidyl-lysine deacetylation(GO:0034983) regulation of skeletal muscle fiber development(GO:0048742)
0.2 0.6 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.2 0.6 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 0.6 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.1 0.6 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0 0.6 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.6 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.6 GO:0043268 positive regulation of potassium ion transport(GO:0043268)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 20 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 2.2 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.0 2.2 GO:0044295 axonal growth cone(GO:0044295)
0.0 1.5 GO:0005913 cell-cell adherens junction(GO:0005913)
0.2 0.9 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.8 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.8 GO:0034704 calcium channel complex(GO:0034704)
0.2 0.6 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.6 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 0.5 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.4 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.4 GO:0034464 BBSome(GO:0034464)
0.0 0.3 GO:0001740 Barr body(GO:0001740)
0.0 0.3 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.3 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 0.2 GO:0034684 integrin alphav-beta5 complex(GO:0034684)
0.1 0.2 GO:0071438 NADPH oxidase complex(GO:0043020) invadopodium membrane(GO:0071438)
0.1 0.2 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 0.2 GO:0000938 GARP complex(GO:0000938)
0.0 0.2 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 37 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.7 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 2.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 2.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.6 2.2 GO:0050436 microfibril binding(GO:0050436)
0.1 1.8 GO:0042805 actinin binding(GO:0042805)
0.1 1.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 1.0 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.9 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.9 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 0.8 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 0.8 GO:0015279 store-operated calcium channel activity(GO:0015279) inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.8 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.7 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 0.6 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.6 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.6 GO:0001221 transcription cofactor binding(GO:0001221)
0.1 0.5 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.5 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.5 GO:0030215 semaphorin receptor binding(GO:0030215)