Motif ID: Nr2e3
Z-value: 0.645
Transcription factors associated with Nr2e3:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Nr2e3 | ENSMUSG00000032292.2 | Nr2e3 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 2.2 | GO:0003345 | proepicardium cell migration involved in pericardium morphogenesis(GO:0003345) |
0.2 | 1.1 | GO:0048133 | germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728) |
0.2 | 0.6 | GO:0036091 | positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091) |
0.2 | 0.6 | GO:0006269 | DNA replication, synthesis of RNA primer(GO:0006269) |
0.1 | 0.7 | GO:1903056 | regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056) |
0.1 | 0.9 | GO:2000809 | neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) positive regulation of synaptic vesicle clustering(GO:2000809) |
0.1 | 0.6 | GO:0061343 | cell adhesion involved in heart morphogenesis(GO:0061343) |
0.1 | 0.9 | GO:0030035 | microspike assembly(GO:0030035) |
0.1 | 0.3 | GO:0060821 | inactivation of X chromosome by DNA methylation(GO:0060821) |
0.1 | 0.5 | GO:0060075 | regulation of resting membrane potential(GO:0060075) |
0.1 | 2.2 | GO:0032967 | positive regulation of collagen biosynthetic process(GO:0032967) |
0.1 | 0.3 | GO:0045113 | regulation of integrin biosynthetic process(GO:0045113) |
0.1 | 2.7 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
0.1 | 0.7 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
0.1 | 0.7 | GO:0034983 | peptidyl-lysine deacetylation(GO:0034983) regulation of skeletal muscle fiber development(GO:0048742) |
0.1 | 0.2 | GO:0010871 | negative regulation of receptor biosynthetic process(GO:0010871) |
0.1 | 0.6 | GO:0061088 | sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088) |
0.1 | 0.4 | GO:0071699 | olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699) |
0.1 | 0.4 | GO:0090336 | positive regulation of brown fat cell differentiation(GO:0090336) |
0.1 | 0.5 | GO:0015721 | bile acid and bile salt transport(GO:0015721) |
0.1 | 0.4 | GO:0051611 | negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
0.1 | 0.3 | GO:0036508 | protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) protein demannosylation(GO:0036507) protein alpha-1,2-demannosylation(GO:0036508) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382) |
0.0 | 0.5 | GO:0090557 | establishment of endothelial intestinal barrier(GO:0090557) |
0.0 | 0.4 | GO:0015074 | DNA integration(GO:0015074) |
0.0 | 0.6 | GO:0043011 | myeloid dendritic cell differentiation(GO:0043011) |
0.0 | 0.5 | GO:0051791 | medium-chain fatty acid metabolic process(GO:0051791) |
0.0 | 0.6 | GO:0009312 | oligosaccharide biosynthetic process(GO:0009312) |
0.0 | 1.1 | GO:0002091 | negative regulation of receptor internalization(GO:0002091) |
0.0 | 0.2 | GO:0086013 | membrane repolarization during cardiac muscle cell action potential(GO:0086013) |
0.0 | 0.2 | GO:1903887 | motile primary cilium assembly(GO:1903887) |
0.0 | 0.8 | GO:0014051 | gamma-aminobutyric acid secretion(GO:0014051) |
0.0 | 0.4 | GO:0042447 | hormone catabolic process(GO:0042447) |
0.0 | 0.2 | GO:0071361 | cellular response to ethanol(GO:0071361) |
0.0 | 0.1 | GO:0003289 | atrial septum primum morphogenesis(GO:0003289) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910) |
0.0 | 0.2 | GO:0090091 | positive regulation of extracellular matrix disassembly(GO:0090091) |
0.0 | 0.1 | GO:0008627 | intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627) |
0.0 | 0.2 | GO:1990564 | protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592) |
0.0 | 0.1 | GO:0010040 | response to iron(II) ion(GO:0010040) |
0.0 | 0.1 | GO:0042713 | operant conditioning(GO:0035106) sperm ejaculation(GO:0042713) |
0.0 | 0.5 | GO:0090005 | negative regulation of establishment of protein localization to plasma membrane(GO:0090005) |
0.0 | 0.1 | GO:0032472 | Golgi calcium ion transport(GO:0032472) |
0.0 | 0.2 | GO:0009404 | toxin metabolic process(GO:0009404) |
0.0 | 0.4 | GO:0043171 | peptide catabolic process(GO:0043171) |
0.0 | 0.3 | GO:0021527 | spinal cord association neuron differentiation(GO:0021527) |
0.0 | 0.4 | GO:0030033 | microvillus assembly(GO:0030033) |
0.0 | 0.1 | GO:0002317 | plasma cell differentiation(GO:0002317) |
0.0 | 0.0 | GO:0048388 | endosomal lumen acidification(GO:0048388) synaptic vesicle lumen acidification(GO:0097401) |
0.0 | 0.8 | GO:0030901 | midbrain development(GO:0030901) |
0.0 | 0.2 | GO:0021860 | pyramidal neuron development(GO:0021860) |
0.0 | 0.5 | GO:0021591 | ventricular system development(GO:0021591) |
0.0 | 0.2 | GO:0060052 | neurofilament cytoskeleton organization(GO:0060052) |
0.0 | 0.3 | GO:0007097 | nuclear migration(GO:0007097) |
0.0 | 0.2 | GO:1904424 | regulation of GTP binding(GO:1904424) |
0.0 | 0.1 | GO:0071420 | cellular response to histamine(GO:0071420) |
0.0 | 1.0 | GO:0050885 | neuromuscular process controlling balance(GO:0050885) |
0.0 | 0.6 | GO:0043268 | positive regulation of potassium ion transport(GO:0043268) |
0.0 | 0.3 | GO:0097320 | membrane tubulation(GO:0097320) |
0.0 | 0.1 | GO:0090074 | negative regulation of protein homodimerization activity(GO:0090074) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 2.2 | GO:0038045 | large latent transforming growth factor-beta complex(GO:0038045) |
0.2 | 0.6 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
0.2 | 0.9 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
0.1 | 0.8 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
0.1 | 0.2 | GO:0034684 | integrin alphav-beta5 complex(GO:0034684) |
0.1 | 0.5 | GO:0046581 | intercellular canaliculus(GO:0046581) |
0.1 | 0.2 | GO:0071438 | NADPH oxidase complex(GO:0043020) invadopodium membrane(GO:0071438) |
0.1 | 0.2 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
0.0 | 0.3 | GO:0001740 | Barr body(GO:0001740) |
0.0 | 2.2 | GO:0044295 | axonal growth cone(GO:0044295) |
0.0 | 0.4 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
0.0 | 0.4 | GO:0034464 | BBSome(GO:0034464) |
0.0 | 0.2 | GO:0000938 | GARP complex(GO:0000938) |
0.0 | 0.6 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
0.0 | 0.3 | GO:0030122 | AP-2 adaptor complex(GO:0030122) |
0.0 | 1.5 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
0.0 | 0.1 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
0.0 | 0.8 | GO:0034704 | calcium channel complex(GO:0034704) |
0.0 | 0.2 | GO:0045095 | keratin filament(GO:0045095) |
0.0 | 0.3 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 2.2 | GO:0050436 | microfibril binding(GO:0050436) |
0.1 | 0.9 | GO:0070699 | type II activin receptor binding(GO:0070699) |
0.1 | 0.5 | GO:0015349 | thyroid hormone transmembrane transporter activity(GO:0015349) |
0.1 | 2.5 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
0.1 | 0.3 | GO:0016716 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716) |
0.1 | 0.6 | GO:0015016 | [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016) |
0.1 | 0.6 | GO:0008499 | UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499) |
0.1 | 0.2 | GO:0030171 | voltage-gated proton channel activity(GO:0030171) |
0.1 | 0.8 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
0.1 | 0.2 | GO:0016715 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715) |
0.1 | 0.8 | GO:0015279 | store-operated calcium channel activity(GO:0015279) inositol 1,4,5 trisphosphate binding(GO:0070679) |
0.1 | 1.8 | GO:0042805 | actinin binding(GO:0042805) |
0.1 | 0.2 | GO:0071568 | UFM1 transferase activity(GO:0071568) |
0.1 | 1.1 | GO:0042043 | neurexin family protein binding(GO:0042043) |
0.1 | 0.4 | GO:0004303 | estradiol 17-beta-dehydrogenase activity(GO:0004303) |
0.0 | 0.2 | GO:0019960 | C-X3-C chemokine binding(GO:0019960) |
0.0 | 0.5 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
0.0 | 0.2 | GO:0086008 | voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008) |
0.0 | 0.8 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
0.0 | 0.7 | GO:0031078 | histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) |
0.0 | 1.0 | GO:0070412 | R-SMAD binding(GO:0070412) |
0.0 | 0.3 | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) |
0.0 | 0.6 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
0.0 | 0.2 | GO:0005522 | profilin binding(GO:0005522) |
0.0 | 2.6 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
0.0 | 0.6 | GO:0001221 | transcription cofactor binding(GO:0001221) |
0.0 | 0.9 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
0.0 | 0.2 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
0.0 | 0.3 | GO:0030159 | receptor signaling complex scaffold activity(GO:0030159) |
0.0 | 0.1 | GO:0050786 | arachidonic acid binding(GO:0050544) RAGE receptor binding(GO:0050786) |
0.0 | 0.5 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
0.0 | 0.5 | GO:0016414 | O-octanoyltransferase activity(GO:0016414) |
0.0 | 0.0 | GO:0072320 | volume-sensitive chloride channel activity(GO:0072320) |
0.0 | 0.2 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
0.0 | 0.4 | GO:0001103 | RNA polymerase II repressing transcription factor binding(GO:0001103) |
0.0 | 3.7 | GO:0001228 | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
0.0 | 0.3 | GO:0001158 | enhancer sequence-specific DNA binding(GO:0001158) |