Motif ID: Pax5

Z-value: 1.830


Transcription factors associated with Pax5:

Gene SymbolEntrez IDGene Name
Pax5 ENSMUSG00000014030.9 Pax5

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pax5mm10_v2_chr4_-_44704006_447040060.203.7e-01Click!


Activity profile for motif Pax5.

activity profile for motif Pax5


Sorted Z-values histogram for motif Pax5

Sorted Z-values for motif Pax5



Network of associatons between targets according to the STRING database.



First level regulatory network of Pax5

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_+_127725392 5.702 ENSMUST00000026466.3
 Tac2
tachykinin 2
chr11_-_102897123 4.715 ENSMUST00000067444.3
 Gfap
glial fibrillary acidic protein
chr1_-_190170671 4.395 ENSMUST00000175916.1
 Prox1
prospero-related homeobox 1
chr1_-_190170178 4.305 ENSMUST00000177288.1
 Prox1
prospero-related homeobox 1
chr16_-_37384915 3.875 ENSMUST00000114787.1
ENSMUST00000114782.1
ENSMUST00000023526.2
ENSMUST00000114775.1
 Stxbp5l



syntaxin binding protein 5-like



chr5_+_89027959 3.508 ENSMUST00000130041.1
 Slc4a4
solute carrier family 4 (anion exchanger), member 4
chr11_-_77894096 3.334 ENSMUST00000017597.4
 Pipox
pipecolic acid oxidase
chr11_-_102897146 3.136 ENSMUST00000077902.4
 Gfap
glial fibrillary acidic protein
chr2_+_91945703 3.072 ENSMUST00000178895.1
 Gm9821
predicted gene 9821
chr16_-_37384940 2.999 ENSMUST00000114781.1
ENSMUST00000114780.1
 Stxbp5l

syntaxin binding protein 5-like

chr14_+_45219993 2.804 ENSMUST00000146150.1
 Gpr137c
G protein-coupled receptor 137C
chr18_+_65873478 2.698 ENSMUST00000025395.8
ENSMUST00000173530.1
 Grp

gastrin releasing peptide

chr8_+_125995102 2.669 ENSMUST00000046765.8
 Kcnk1
potassium channel, subfamily K, member 1
chr15_+_103503261 2.612 ENSMUST00000023132.3
 Pde1b
phosphodiesterase 1B, Ca2+-calmodulin dependent
chr19_-_57008187 2.602 ENSMUST00000118800.1
ENSMUST00000111584.2
ENSMUST00000122359.1
ENSMUST00000148049.1
 Afap1l2



actin filament associated protein 1-like 2



chr10_-_128919259 2.535 ENSMUST00000149961.1
ENSMUST00000026406.7
 Rdh5

retinol dehydrogenase 5

chr7_-_116443439 2.411 ENSMUST00000170430.1
 Pik3c2a
phosphatidylinositol 3-kinase, C2 domain containing, alpha polypeptide
chr11_-_102946688 2.345 ENSMUST00000057849.5
 C1ql1
complement component 1, q subcomponent-like 1
chr16_+_43235856 2.342 ENSMUST00000146708.1
 Zbtb20
zinc finger and BTB domain containing 20
chr3_+_89520152 2.285 ENSMUST00000000811.7
 Kcnn3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 346 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.9 8.7 GO:0090425 hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
1.4 8.2 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
0.3 7.2 GO:0015701 bicarbonate transport(GO:0015701)
0.1 6.6 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.2 6.2 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
1.0 5.7 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 4.7 GO:0017145 stem cell division(GO:0017145)
0.0 4.0 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.3 3.8 GO:0070842 aggresome assembly(GO:0070842)
0.1 3.6 GO:0046785 microtubule polymerization(GO:0046785)
1.1 3.3 GO:0006553 lysine metabolic process(GO:0006553)
0.5 3.3 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.4 3.1 GO:0045213 neurotransmitter receptor metabolic process(GO:0045213)
0.1 3.1 GO:0030033 microvillus assembly(GO:0030033)
0.0 3.0 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.2 2.9 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.7 2.8 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.5 2.7 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.2 2.7 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.2 2.7 GO:0015693 magnesium ion transport(GO:0015693)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 149 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 11.6 GO:0016323 basolateral plasma membrane(GO:0016323)
2.0 7.9 GO:0097450 astrocyte end-foot(GO:0097450)
0.1 6.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 5.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.4 5.7 GO:0005614 interstitial matrix(GO:0005614)
0.1 5.4 GO:0031201 SNARE complex(GO:0031201)
0.0 4.6 GO:0016605 PML body(GO:0016605)
0.1 3.4 GO:0005871 kinesin complex(GO:0005871)
0.1 3.2 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 3.1 GO:0005923 bicellular tight junction(GO:0005923)
0.3 2.9 GO:0030478 actin cap(GO:0030478)
0.5 2.8 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.1 2.7 GO:0030014 CCR4-NOT complex(GO:0030014)
0.8 2.5 GO:0071953 elastic fiber(GO:0071953)
0.1 2.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 2.3 GO:0031594 neuromuscular junction(GO:0031594)
0.0 2.3 GO:0005802 trans-Golgi network(GO:0005802)
0.1 2.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 2.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 2.1 GO:0005581 collagen trimer(GO:0005581)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 216 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 12.4 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 8.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
1.1 8.7 GO:0050693 LBD domain binding(GO:0050693)
0.6 6.9 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.1 6.8 GO:0019905 syntaxin binding(GO:0019905)
0.2 5.8 GO:0017091 AU-rich element binding(GO:0017091)
1.9 5.7 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.2 4.0 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 3.7 GO:0003777 microtubule motor activity(GO:0003777)
0.2 3.5 GO:0001968 fibronectin binding(GO:0001968)
0.8 3.4 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.3 3.3 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.4 3.0 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.3 2.9 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.2 2.8 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 2.8 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.2 2.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 2.7 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 2.7 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 2.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)