Motif ID: Pou4f1_Pou6f1
Z-value: 0.704
Transcription factors associated with Pou4f1_Pou6f1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Pou4f1 | ENSMUSG00000048349.8 | Pou4f1 |
Pou6f1 | ENSMUSG00000009739.10 | Pou6f1 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Pou6f1 | mm10_v2_chr15_-_100599983_100600039 | 0.70 | 2.0e-04 | Click! |
Pou4f1 | mm10_v2_chr14_-_104467984_104468041 | -0.53 | 9.0e-03 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.6 | 8.1 | GO:0048133 | germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728) |
0.7 | 2.8 | GO:2000525 | regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) |
0.7 | 2.0 | GO:1904685 | positive regulation of metalloendopeptidase activity(GO:1904685) |
0.6 | 1.9 | GO:0086046 | membrane depolarization during SA node cell action potential(GO:0086046) |
0.6 | 1.9 | GO:1904395 | regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) |
0.4 | 3.1 | GO:0071699 | olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699) |
0.4 | 2.2 | GO:2000483 | negative regulation of interleukin-8 secretion(GO:2000483) |
0.4 | 1.1 | GO:0042939 | glutathione transport(GO:0034635) tripeptide transport(GO:0042939) |
0.2 | 1.2 | GO:0061551 | trigeminal ganglion development(GO:0061551) |
0.2 | 0.6 | GO:2000564 | CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187) |
0.2 | 0.8 | GO:0014846 | esophagus smooth muscle contraction(GO:0014846) |
0.2 | 0.4 | GO:0014877 | response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
0.2 | 0.6 | GO:0010986 | positive regulation of lipoprotein particle clearance(GO:0010986) |
0.2 | 0.6 | GO:0045404 | positive regulation of interleukin-4 biosynthetic process(GO:0045404) |
0.2 | 1.4 | GO:0097460 | positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import into cell(GO:0097460) |
0.2 | 0.5 | GO:0051542 | elastin biosynthetic process(GO:0051542) |
0.1 | 0.5 | GO:1903378 | positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378) |
0.1 | 1.9 | GO:1901629 | regulation of presynaptic membrane organization(GO:1901629) |
0.1 | 0.6 | GO:0035093 | spermatogenesis, exchange of chromosomal proteins(GO:0035093) |
0.1 | 0.4 | GO:1902396 | protein localization to bicellular tight junction(GO:1902396) |
0.1 | 0.6 | GO:0040031 | snRNA modification(GO:0040031) |
0.1 | 0.9 | GO:0033147 | negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147) |
0.1 | 1.4 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
0.1 | 1.0 | GO:0042118 | endothelial cell activation(GO:0042118) |
0.1 | 0.5 | GO:0035356 | cellular triglyceride homeostasis(GO:0035356) |
0.1 | 0.2 | GO:0033866 | nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033) |
0.1 | 0.2 | GO:1901420 | negative regulation of response to alcohol(GO:1901420) |
0.1 | 0.6 | GO:0090074 | negative regulation of protein homodimerization activity(GO:0090074) |
0.1 | 0.6 | GO:0072257 | metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307) |
0.1 | 0.3 | GO:0002457 | T cell antigen processing and presentation(GO:0002457) |
0.1 | 0.4 | GO:1903361 | protein localization to basolateral plasma membrane(GO:1903361) |
0.1 | 0.2 | GO:0035106 | operant conditioning(GO:0035106) |
0.1 | 0.2 | GO:0090258 | negative regulation of mitochondrial fission(GO:0090258) |
0.1 | 0.2 | GO:0010808 | positive regulation of synaptic vesicle priming(GO:0010808) positive regulation of synaptic vesicle exocytosis(GO:2000302) |
0.1 | 0.2 | GO:0009414 | response to water deprivation(GO:0009414) |
0.1 | 1.6 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
0.1 | 1.3 | GO:0002076 | osteoblast development(GO:0002076) |
0.1 | 0.4 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
0.1 | 0.3 | GO:0003406 | retinal pigment epithelium development(GO:0003406) |
0.1 | 0.7 | GO:0051764 | actin crosslink formation(GO:0051764) |
0.0 | 0.4 | GO:0000712 | resolution of meiotic recombination intermediates(GO:0000712) |
0.0 | 0.2 | GO:0090310 | negative regulation of methylation-dependent chromatin silencing(GO:0090310) |
0.0 | 0.5 | GO:0009312 | oligosaccharide biosynthetic process(GO:0009312) |
0.0 | 0.6 | GO:0021891 | olfactory bulb interneuron development(GO:0021891) |
0.0 | 0.7 | GO:0045475 | locomotor rhythm(GO:0045475) |
0.0 | 0.6 | GO:0042541 | hemoglobin biosynthetic process(GO:0042541) |
0.0 | 0.4 | GO:0036037 | CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
0.0 | 0.3 | GO:1903608 | protein localization to cytoplasmic stress granule(GO:1903608) |
0.0 | 0.1 | GO:0042796 | snRNA transcription from RNA polymerase III promoter(GO:0042796) |
0.0 | 0.1 | GO:0031860 | telomeric 3' overhang formation(GO:0031860) |
0.0 | 0.2 | GO:0035095 | behavioral response to nicotine(GO:0035095) |
0.0 | 0.2 | GO:0045200 | establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) |
0.0 | 0.1 | GO:0002922 | positive regulation of humoral immune response(GO:0002922) progesterone receptor signaling pathway(GO:0050847) |
0.0 | 0.2 | GO:0010908 | regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730) |
0.0 | 1.7 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
0.0 | 0.2 | GO:0046036 | GTP biosynthetic process(GO:0006183) CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036) |
0.0 | 0.1 | GO:1902774 | late endosome to lysosome transport(GO:1902774) |
0.0 | 0.1 | GO:0048859 | formation of anatomical boundary(GO:0048859) |
0.0 | 0.4 | GO:0001553 | luteinization(GO:0001553) |
0.0 | 0.4 | GO:0035025 | positive regulation of Rho protein signal transduction(GO:0035025) |
0.0 | 1.7 | GO:0060976 | coronary vasculature development(GO:0060976) |
0.0 | 0.1 | GO:1902661 | negative regulation of histone H3-K9 dimethylation(GO:1900110) regulation of glucose mediated signaling pathway(GO:1902659) positive regulation of glucose mediated signaling pathway(GO:1902661) |
0.0 | 0.1 | GO:0036337 | Fas signaling pathway(GO:0036337) |
0.0 | 0.1 | GO:0045835 | negative regulation of meiotic nuclear division(GO:0045835) |
0.0 | 0.4 | GO:0007097 | nuclear migration(GO:0007097) |
0.0 | 0.9 | GO:0086010 | membrane depolarization during action potential(GO:0086010) |
0.0 | 0.1 | GO:0031119 | tRNA pseudouridine synthesis(GO:0031119) |
0.0 | 1.9 | GO:0072332 | intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332) |
0.0 | 0.1 | GO:0071894 | histone H2B conserved C-terminal lysine ubiquitination(GO:0071894) |
0.0 | 0.1 | GO:0089711 | L-glutamate transmembrane transport(GO:0089711) |
0.0 | 0.5 | GO:0061014 | positive regulation of mRNA catabolic process(GO:0061014) |
0.0 | 0.6 | GO:0009395 | phospholipid catabolic process(GO:0009395) |
0.0 | 0.2 | GO:1901844 | regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) |
0.0 | 0.2 | GO:0046548 | retinal rod cell development(GO:0046548) |
0.0 | 0.5 | GO:0043550 | regulation of lipid kinase activity(GO:0043550) |
0.0 | 1.3 | GO:0048709 | oligodendrocyte differentiation(GO:0048709) |
0.0 | 0.1 | GO:2000255 | negative regulation of male germ cell proliferation(GO:2000255) |
0.0 | 0.1 | GO:0042136 | neurotransmitter biosynthetic process(GO:0042136) |
0.0 | 0.2 | GO:0010758 | regulation of macrophage chemotaxis(GO:0010758) |
0.0 | 0.0 | GO:1901475 | pyruvate transmembrane transport(GO:1901475) |
0.0 | 0.2 | GO:0060252 | positive regulation of glial cell proliferation(GO:0060252) |
0.0 | 0.1 | GO:0007296 | vitellogenesis(GO:0007296) |
0.0 | 1.1 | GO:0043149 | contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149) |
0.0 | 0.1 | GO:0007256 | activation of JNKK activity(GO:0007256) |
0.0 | 0.2 | GO:0016486 | peptide hormone processing(GO:0016486) |
0.0 | 0.1 | GO:2000780 | negative regulation of double-strand break repair(GO:2000780) |
0.0 | 0.3 | GO:0033539 | fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539) |
0.0 | 0.1 | GO:0090188 | negative regulation of pancreatic juice secretion(GO:0090188) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 1.9 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
0.2 | 1.4 | GO:0097433 | dense body(GO:0097433) |
0.1 | 0.5 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
0.1 | 0.4 | GO:0001533 | cornified envelope(GO:0001533) |
0.1 | 0.3 | GO:0005899 | insulin receptor complex(GO:0005899) |
0.1 | 1.6 | GO:1902710 | GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711) |
0.1 | 0.8 | GO:0071439 | clathrin complex(GO:0071439) |
0.1 | 0.3 | GO:0097165 | nuclear stress granule(GO:0097165) |
0.1 | 0.5 | GO:0035032 | phosphatidylinositol 3-kinase complex, class III(GO:0035032) |
0.1 | 0.3 | GO:0045251 | mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251) |
0.1 | 0.2 | GO:0048786 | presynaptic active zone(GO:0048786) |
0.1 | 0.9 | GO:0034706 | voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706) |
0.0 | 0.6 | GO:0042612 | MHC class I protein complex(GO:0042612) |
0.0 | 1.9 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
0.0 | 0.5 | GO:0000177 | cytoplasmic exosome (RNase complex)(GO:0000177) |
0.0 | 0.8 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
0.0 | 0.7 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
0.0 | 0.2 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
0.0 | 0.1 | GO:0030870 | Mre11 complex(GO:0030870) |
0.0 | 0.4 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
0.0 | 0.4 | GO:0031143 | pseudopodium(GO:0031143) |
0.0 | 1.9 | GO:0031594 | neuromuscular junction(GO:0031594) |
0.0 | 9.6 | GO:0005667 | transcription factor complex(GO:0005667) |
0.0 | 0.2 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
0.0 | 0.3 | GO:0036038 | MKS complex(GO:0036038) |
0.0 | 0.3 | GO:0097539 | ciliary transition fiber(GO:0097539) |
0.0 | 0.5 | GO:0030140 | trans-Golgi network transport vesicle(GO:0030140) |
0.0 | 0.1 | GO:0031315 | extrinsic component of mitochondrial outer membrane(GO:0031315) |
0.0 | 0.2 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
0.0 | 0.1 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
0.0 | 0.1 | GO:0097255 | R2TP complex(GO:0097255) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 1.9 | GO:0035373 | chondroitin sulfate proteoglycan binding(GO:0035373) |
0.3 | 1.9 | GO:0086007 | voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007) |
0.3 | 1.4 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
0.3 | 1.0 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
0.2 | 0.7 | GO:0004658 | propionyl-CoA carboxylase activity(GO:0004658) |
0.2 | 2.0 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
0.2 | 1.4 | GO:0015091 | ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510) |
0.2 | 1.0 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
0.2 | 0.5 | GO:0003846 | 2-acylglycerol O-acyltransferase activity(GO:0003846) |
0.2 | 0.8 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
0.2 | 0.5 | GO:0004008 | copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682) |
0.2 | 1.1 | GO:0015651 | quaternary ammonium group transmembrane transporter activity(GO:0015651) |
0.1 | 2.8 | GO:0005003 | ephrin receptor activity(GO:0005003) |
0.1 | 0.6 | GO:0008970 | phosphatidylcholine 1-acylhydrolase activity(GO:0008970) |
0.1 | 0.7 | GO:0005250 | A-type (transient outward) potassium channel activity(GO:0005250) |
0.1 | 0.1 | GO:0001851 | complement component C3b binding(GO:0001851) |
0.1 | 0.4 | GO:0004556 | alpha-amylase activity(GO:0004556) |
0.1 | 0.5 | GO:0050816 | phosphothreonine binding(GO:0050816) |
0.1 | 1.2 | GO:0038191 | neuropilin binding(GO:0038191) |
0.1 | 0.4 | GO:0004859 | phospholipase inhibitor activity(GO:0004859) phospholipase A2 inhibitor activity(GO:0019834) |
0.1 | 0.6 | GO:0004301 | epoxide hydrolase activity(GO:0004301) |
0.1 | 0.9 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
0.1 | 0.4 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
0.1 | 1.6 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
0.1 | 1.2 | GO:0030881 | beta-2-microglobulin binding(GO:0030881) |
0.1 | 1.9 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
0.1 | 0.4 | GO:0042296 | ISG15 transferase activity(GO:0042296) |
0.1 | 0.2 | GO:0046964 | 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964) |
0.1 | 0.3 | GO:0004954 | icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955) |
0.1 | 0.4 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
0.1 | 0.9 | GO:0008599 | protein phosphatase type 1 regulator activity(GO:0008599) |
0.0 | 0.6 | GO:0048273 | mitogen-activated protein kinase p38 binding(GO:0048273) |
0.0 | 1.8 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
0.0 | 0.9 | GO:0031402 | sodium ion binding(GO:0031402) |
0.0 | 0.6 | GO:0004623 | phospholipase A2 activity(GO:0004623) |
0.0 | 0.2 | GO:0070579 | methylcytosine dioxygenase activity(GO:0070579) |
0.0 | 0.6 | GO:0016594 | glycine binding(GO:0016594) |
0.0 | 0.1 | GO:0004565 | beta-galactosidase activity(GO:0004565) |
0.0 | 0.2 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
0.0 | 0.1 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
0.0 | 0.2 | GO:0004779 | sulfate adenylyltransferase activity(GO:0004779) |
0.0 | 0.7 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
0.0 | 0.3 | GO:0008758 | thiamine-pyrophosphatase activity(GO:0004787) UDP-2,3-diacylglucosamine hydrolase activity(GO:0008758) dATP pyrophosphohydrolase activity(GO:0008828) dihydroneopterin monophosphate phosphatase activity(GO:0019176) dihydroneopterin triphosphate pyrophosphohydrolase activity(GO:0019177) dTTP diphosphatase activity(GO:0036218) phosphocholine hydrolase activity(GO:0044606) |
0.0 | 0.2 | GO:0055131 | C3HC4-type RING finger domain binding(GO:0055131) |
0.0 | 0.2 | GO:0015165 | pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165) |
0.0 | 1.9 | GO:0002039 | p53 binding(GO:0002039) |
0.0 | 0.2 | GO:0004889 | acetylcholine-activated cation-selective channel activity(GO:0004889) |
0.0 | 0.4 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
0.0 | 0.5 | GO:0003746 | translation elongation factor activity(GO:0003746) |
0.0 | 0.1 | GO:0016308 | 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308) |
0.0 | 0.1 | GO:0008499 | UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499) |
0.0 | 0.1 | GO:0032184 | SUMO polymer binding(GO:0032184) |
0.0 | 0.2 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
0.0 | 0.3 | GO:0052890 | oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor(GO:0052890) |
0.0 | 0.0 | GO:0050833 | pyruvate transmembrane transporter activity(GO:0050833) |
0.0 | 0.2 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
0.0 | 0.2 | GO:0030159 | receptor signaling complex scaffold activity(GO:0030159) |
0.0 | 0.1 | GO:0034951 | pivalyl-CoA mutase activity(GO:0034784) o-hydroxylaminobenzoate mutase activity(GO:0034951) lupeol synthase activity(GO:0042299) beta-amyrin synthase activity(GO:0042300) baruol synthase activity(GO:0080011) |