Motif ID: Pou4f1_Pou6f1

Z-value: 0.704

Transcription factors associated with Pou4f1_Pou6f1:

Gene SymbolEntrez IDGene Name
Pou4f1 ENSMUSG00000048349.8 Pou4f1
Pou6f1 ENSMUSG00000009739.10 Pou6f1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pou6f1mm10_v2_chr15_-_100599983_1006000390.702.0e-04Click!
Pou4f1mm10_v2_chr14_-_104467984_104468041-0.539.0e-03Click!


Activity profile for motif Pou4f1_Pou6f1.

activity profile for motif Pou4f1_Pou6f1


Sorted Z-values histogram for motif Pou4f1_Pou6f1

Sorted Z-values for motif Pou4f1_Pou6f1



Network of associatons between targets according to the STRING database.



First level regulatory network of Pou4f1_Pou6f1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_-_22439719 4.234 ENSMUST00000079601.6
 Etv5
ets variant gene 5
chr16_-_22439570 3.819 ENSMUST00000170393.1
 Etv5
ets variant gene 5
chr2_-_77519565 1.943 ENSMUST00000111830.2
 Zfp385b
zinc finger protein 385B
chr14_-_30353468 1.925 ENSMUST00000112249.1
 Cacna1d
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr6_-_36811361 1.917 ENSMUST00000101534.1
 Ptn
pleiotrophin
chr15_+_18818895 1.749 ENSMUST00000166873.2
 Cdh10
cadherin 10
chr13_+_104287855 1.707 ENSMUST00000065766.6
 Adamts6
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 6
chr16_+_91269759 1.610 ENSMUST00000056882.5
 Olig1
oligodendrocyte transcription factor 1
chr5_+_137350371 1.424 ENSMUST00000166239.1
ENSMUST00000111054.1
 Ephb4

Eph receptor B4

chr4_+_154964117 1.407 ENSMUST00000030931.4
ENSMUST00000070953.4
 Pank4

pantothenate kinase 4

chr15_-_100599864 1.388 ENSMUST00000177247.2
ENSMUST00000177505.2
 Pou6f1

POU domain, class 6, transcription factor 1

chr9_-_40346290 1.369 ENSMUST00000121357.1
 Gramd1b
GRAM domain containing 1B
chr9_-_103222063 1.365 ENSMUST00000170904.1
 Trf
transferrin
chr15_-_100599983 1.291 ENSMUST00000073837.6
 Pou6f1
POU domain, class 6, transcription factor 1
chr1_-_56978534 1.284 ENSMUST00000177282.1
 Satb2
special AT-rich sequence binding protein 2
chr1_-_166002613 1.154 ENSMUST00000177358.1
ENSMUST00000160908.1
ENSMUST00000027850.8
ENSMUST00000160260.2
 Pou2f1



POU domain, class 2, transcription factor 1



chr5_-_70842617 1.106 ENSMUST00000031119.1
 Gabrg1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chr19_+_8591254 1.106 ENSMUST00000010251.3
ENSMUST00000170817.1
 Slc22a8

solute carrier family 22 (organic anion transporter), member 8

chr15_+_81811414 1.082 ENSMUST00000023024.7
 Tef
thyrotroph embryonic factor
chr5_-_39644634 1.049 ENSMUST00000053116.6
 Hs3st1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 88 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.6 8.1 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.4 3.1 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.7 2.8 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.4 2.2 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.7 2.0 GO:1904685 positive regulation of metalloendopeptidase activity(GO:1904685)
0.6 1.9 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.6 1.9 GO:1904395 regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.1 1.9 GO:1901629 regulation of presynaptic membrane organization(GO:1901629)
0.0 1.9 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 1.7 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.7 GO:0060976 coronary vasculature development(GO:0060976)
0.1 1.6 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.2 1.4 GO:0097460 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import into cell(GO:0097460)
0.1 1.4 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 1.3 GO:0002076 osteoblast development(GO:0002076)
0.0 1.3 GO:0048709 oligodendrocyte differentiation(GO:0048709)
0.2 1.2 GO:0061551 trigeminal ganglion development(GO:0061551)
0.4 1.1 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.0 1.1 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.1 1.0 GO:0042118 endothelial cell activation(GO:0042118)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 31 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 9.6 GO:0005667 transcription factor complex(GO:0005667)
0.2 1.9 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 1.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 1.9 GO:0031594 neuromuscular junction(GO:0031594)
0.1 1.6 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.2 1.4 GO:0097433 dense body(GO:0097433)
0.1 0.9 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.1 0.8 GO:0071439 clathrin complex(GO:0071439)
0.0 0.8 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.7 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.6 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.5 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 0.5 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.5 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.5 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 0.4 GO:0001533 cornified envelope(GO:0001533)
0.0 0.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.4 GO:0031143 pseudopodium(GO:0031143)
0.1 0.3 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.3 GO:0097165 nuclear stress granule(GO:0097165)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 58 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.8 GO:0005003 ephrin receptor activity(GO:0005003)
0.2 2.0 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.6 1.9 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.3 1.9 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.1 1.9 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 1.9 GO:0002039 p53 binding(GO:0002039)
0.0 1.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 1.6 GO:0004890 GABA-A receptor activity(GO:0004890)
0.3 1.4 GO:0004594 pantothenate kinase activity(GO:0004594)
0.2 1.4 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1 1.2 GO:0038191 neuropilin binding(GO:0038191)
0.1 1.2 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.2 1.1 GO:0015651 quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.3 1.0 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2 1.0 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.9 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 0.9 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.0 0.9 GO:0031402 sodium ion binding(GO:0031402)
0.2 0.8 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 0.7 GO:0004658 propionyl-CoA carboxylase activity(GO:0004658)