Motif ID: Nkx6-3_Dbx2_Barx2
Z-value: 0.563
Transcription factors associated with Nkx6-3_Dbx2_Barx2:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Barx2 | ENSMUSG00000032033.10 | Barx2 |
Dbx2 | ENSMUSG00000045608.6 | Dbx2 |
Nkx6-3 | ENSMUSG00000063672.6 | Nkx6-3 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Dbx2 | mm10_v2_chr15_-_95655960_95655960 | 0.21 | 3.3e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 1.8 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
0.2 | 0.7 | GO:0072204 | cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204) |
0.2 | 0.5 | GO:0009193 | pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048) |
0.2 | 0.8 | GO:0015788 | UDP-N-acetylglucosamine transport(GO:0015788) |
0.2 | 0.7 | GO:1901642 | purine nucleoside transmembrane transport(GO:0015860) purine-containing compound transmembrane transport(GO:0072530) nucleoside transmembrane transport(GO:1901642) nucleotide transmembrane transport(GO:1901679) |
0.1 | 0.4 | GO:2000564 | CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187) |
0.1 | 0.6 | GO:0098735 | positive regulation of the force of heart contraction(GO:0098735) |
0.1 | 0.3 | GO:0035633 | maintenance of blood-brain barrier(GO:0035633) |
0.1 | 0.5 | GO:1900170 | prolactin signaling pathway(GO:0038161) negative regulation of glucocorticoid mediated signaling pathway(GO:1900170) |
0.1 | 0.3 | GO:1903903 | regulation of establishment of T cell polarity(GO:1903903) |
0.1 | 2.3 | GO:0071398 | cellular response to fatty acid(GO:0071398) |
0.1 | 0.6 | GO:0010273 | detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169) |
0.1 | 0.6 | GO:0019532 | oxalate transport(GO:0019532) |
0.1 | 0.2 | GO:0003278 | apoptotic process involved in heart morphogenesis(GO:0003278) regulation of vascular wound healing(GO:0061043) glomerular mesangial cell differentiation(GO:0072008) glomerular mesangial cell development(GO:0072144) |
0.1 | 0.6 | GO:0042415 | norepinephrine metabolic process(GO:0042415) |
0.1 | 0.4 | GO:1901162 | serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162) |
0.1 | 0.3 | GO:0032911 | nerve growth factor production(GO:0032902) negative regulation of transforming growth factor beta1 production(GO:0032911) |
0.0 | 0.2 | GO:0038128 | ERBB2 signaling pathway(GO:0038128) |
0.0 | 1.2 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
0.0 | 0.2 | GO:0060690 | epithelial cell differentiation involved in salivary gland development(GO:0060690) |
0.0 | 0.5 | GO:0033572 | transferrin transport(GO:0033572) |
0.0 | 1.7 | GO:1900026 | positive regulation of substrate adhesion-dependent cell spreading(GO:1900026) |
0.0 | 0.2 | GO:0002457 | T cell antigen processing and presentation(GO:0002457) |
0.0 | 0.5 | GO:0016486 | peptide hormone processing(GO:0016486) |
0.0 | 0.2 | GO:0045743 | positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743) |
0.0 | 0.1 | GO:0070560 | protein secretion by platelet(GO:0070560) |
0.0 | 0.1 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
0.0 | 0.3 | GO:0032570 | response to progesterone(GO:0032570) |
0.0 | 0.1 | GO:0042420 | dopamine catabolic process(GO:0042420) |
0.0 | 0.1 | GO:0044028 | DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029) |
0.0 | 0.1 | GO:2001268 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268) |
0.0 | 0.1 | GO:0048630 | skeletal muscle tissue growth(GO:0048630) |
0.0 | 1.2 | GO:0009063 | cellular amino acid catabolic process(GO:0009063) |
0.0 | 0.1 | GO:0006780 | uroporphyrinogen III biosynthetic process(GO:0006780) |
0.0 | 0.2 | GO:0051382 | kinetochore assembly(GO:0051382) |
0.0 | 0.2 | GO:0030497 | fatty acid elongation(GO:0030497) |
0.0 | 0.1 | GO:1903056 | regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056) |
0.0 | 0.1 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
0.0 | 0.2 | GO:0009312 | oligosaccharide biosynthetic process(GO:0009312) |
0.0 | 0.1 | GO:0097186 | amelogenesis(GO:0097186) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 1.7 | GO:0042581 | specific granule(GO:0042581) |
0.1 | 1.8 | GO:0043205 | fibril(GO:0043205) |
0.1 | 1.2 | GO:1902710 | GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711) |
0.0 | 0.3 | GO:0097524 | sperm plasma membrane(GO:0097524) |
0.0 | 0.3 | GO:0031254 | uropod(GO:0001931) cell trailing edge(GO:0031254) |
0.0 | 0.4 | GO:0042612 | MHC class I protein complex(GO:0042612) |
0.0 | 0.1 | GO:0005943 | phosphatidylinositol 3-kinase complex, class IA(GO:0005943) |
0.0 | 0.1 | GO:0005796 | Golgi lumen(GO:0005796) |
0.0 | 0.2 | GO:0005915 | zonula adherens(GO:0005915) |
0.0 | 0.3 | GO:0012510 | trans-Golgi network transport vesicle membrane(GO:0012510) |
0.0 | 0.1 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
0.0 | 0.6 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
0.0 | 0.1 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 1.2 | GO:0001716 | L-amino-acid oxidase activity(GO:0001716) |
0.4 | 1.8 | GO:0005314 | high-affinity glutamate transmembrane transporter activity(GO:0005314) |
0.2 | 0.7 | GO:0015217 | ADP transmembrane transporter activity(GO:0015217) coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122) |
0.2 | 1.5 | GO:0018741 | alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902) |
0.2 | 0.6 | GO:0019770 | IgG receptor activity(GO:0019770) |
0.2 | 0.6 | GO:0086038 | calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038) |
0.1 | 0.4 | GO:0004510 | tryptophan 5-monooxygenase activity(GO:0004510) |
0.1 | 0.5 | GO:0045134 | uridine-diphosphatase activity(GO:0045134) |
0.1 | 0.2 | GO:0019166 | trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166) |
0.1 | 1.2 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
0.1 | 0.7 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
0.1 | 2.3 | GO:0005504 | fatty acid binding(GO:0005504) |
0.1 | 0.6 | GO:0019531 | oxalate transmembrane transporter activity(GO:0019531) |
0.0 | 0.4 | GO:0046703 | natural killer cell lectin-like receptor binding(GO:0046703) |
0.0 | 0.8 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
0.0 | 1.9 | GO:0045296 | cadherin binding(GO:0045296) |
0.0 | 0.1 | GO:0005432 | calcium:sodium antiporter activity(GO:0005432) |
0.0 | 0.8 | GO:0005351 | sugar:proton symporter activity(GO:0005351) |
0.0 | 0.3 | GO:0048406 | nerve growth factor binding(GO:0048406) |
0.0 | 0.3 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
0.0 | 1.2 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
0.0 | 0.2 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
0.0 | 0.1 | GO:0033188 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
0.0 | 0.1 | GO:0051378 | primary amine oxidase activity(GO:0008131) serotonin binding(GO:0051378) |
0.0 | 0.0 | GO:0071568 | UFM1 transferase activity(GO:0071568) |
0.0 | 0.6 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
0.0 | 0.1 | GO:0004852 | uroporphyrinogen-III synthase activity(GO:0004852) |
0.0 | 0.1 | GO:0004889 | acetylcholine-activated cation-selective channel activity(GO:0004889) |
0.0 | 0.4 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |