Motif ID: Tfcp2

Z-value: 1.391


Transcription factors associated with Tfcp2:

Gene SymbolEntrez IDGene Name
Tfcp2 ENSMUSG00000009733.8 Tfcp2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tfcp2mm10_v2_chr15_-_100551959_100552010-0.301.7e-01Click!


Activity profile for motif Tfcp2.

activity profile for motif Tfcp2


Sorted Z-values histogram for motif Tfcp2

Sorted Z-values for motif Tfcp2



Network of associatons between targets according to the STRING database.



First level regulatory network of Tfcp2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_-_26989974 5.967 ENSMUST00000089832.4
 Gmnc
geminin coiled-coil domain containing
chr18_+_60925612 5.632 ENSMUST00000102888.3
ENSMUST00000025519.4
 Camk2a

calcium/calmodulin-dependent protein kinase II alpha

chr14_-_21989475 5.435 ENSMUST00000043409.7
 Zfp503
zinc finger protein 503
chr1_+_107511489 5.178 ENSMUST00000064916.2
 Serpinb2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr8_+_57511833 5.088 ENSMUST00000067925.6
 Hmgb2
high mobility group box 2
chr1_+_107511416 4.877 ENSMUST00000009356.4
 Serpinb2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr14_-_34374617 4.105 ENSMUST00000023826.4
 Sncg
synuclein, gamma
chr6_+_56017489 4.013 ENSMUST00000052827.4
 Ppp1r17
protein phosphatase 1, regulatory subunit 17
chr2_-_102186322 3.967 ENSMUST00000111222.1
ENSMUST00000058790.5
 Ldlrad3

low density lipoprotein receptor class A domain containing 3

chr6_+_5390387 3.775 ENSMUST00000183358.1
 Asb4
ankyrin repeat and SOCS box-containing 4
chr2_-_166155272 3.690 ENSMUST00000088086.3
 Sulf2
sulfatase 2
chr2_-_166155624 3.454 ENSMUST00000109249.2
 Sulf2
sulfatase 2
chr4_-_153482768 3.408 ENSMUST00000105646.2
 Ajap1
adherens junction associated protein 1
chr15_-_85578070 3.378 ENSMUST00000109424.2
 Wnt7b
wingless-related MMTV integration site 7B
chr11_+_98937669 3.184 ENSMUST00000107475.2
ENSMUST00000068133.3
 Rara

retinoic acid receptor, alpha

chr13_-_100786402 3.141 ENSMUST00000174038.1
ENSMUST00000091295.7
ENSMUST00000072119.8
 Ccnb1


cyclin B1


chr9_-_96862903 3.103 ENSMUST00000121077.1
ENSMUST00000124923.1
 Acpl2

acid phosphatase-like 2

chr2_+_163225363 3.078 ENSMUST00000099110.3
ENSMUST00000165937.1
 Tox2

TOX high mobility group box family member 2

chr3_+_134828993 3.074 ENSMUST00000029822.4
 Tacr3
tachykinin receptor 3
chr11_-_89302545 3.029 ENSMUST00000061728.3
 Nog
noggin

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 105 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 10.1 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.5 8.0 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.2 7.4 GO:0006270 DNA replication initiation(GO:0006270)
1.8 7.1 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
1.2 6.1 GO:0035404 histone-serine phosphorylation(GO:0035404)
1.8 5.4 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.7 5.1 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.3 5.1 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.3 4.4 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.2 4.4 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 4.0 GO:0010921 regulation of phosphatase activity(GO:0010921)
0.3 3.9 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.4 3.8 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.1 3.8 GO:0006911 phagocytosis, engulfment(GO:0006911)
1.1 3.4 GO:0072070 establishment or maintenance of polarity of embryonic epithelium(GO:0016332) loop of Henle development(GO:0072070) metanephric loop of Henle development(GO:0072236)
1.1 3.2 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.4 3.1 GO:0070474 positive regulation of uterine smooth muscle contraction(GO:0070474)
0.8 3.0 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.3 3.0 GO:0009186 deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.2 2.7 GO:0070050 neuron cellular homeostasis(GO:0070050)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 54 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 22.5 GO:0005615 extracellular space(GO:0005615)
0.2 8.0 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 5.5 GO:0000785 chromatin(GO:0000785)
0.0 5.1 GO:0000793 condensed chromosome(GO:0000793)
0.5 4.4 GO:0070688 MLL5-L complex(GO:0070688)
0.9 3.8 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 3.6 GO:0005667 transcription factor complex(GO:0005667)
0.8 3.1 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.1 3.1 GO:0032590 dendrite membrane(GO:0032590)
0.6 3.0 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.6 2.9 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 2.5 GO:0016324 apical plasma membrane(GO:0016324)
0.0 2.3 GO:0043679 axon terminus(GO:0043679)
0.1 2.2 GO:0005652 nuclear lamina(GO:0005652)
0.0 2.0 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.2 1.8 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.3 1.6 GO:0031298 replication fork protection complex(GO:0031298)
0.0 1.4 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 1.3 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.3 1.2 GO:0097450 astrocyte end-foot(GO:0097450)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 81 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 10.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 8.5 GO:0003682 chromatin binding(GO:0003682)
0.3 8.0 GO:0032794 GTPase activating protein binding(GO:0032794)
1.4 7.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.9 5.2 GO:0050786 RAGE receptor binding(GO:0050786)
0.1 4.9 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 4.9 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 4.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.4 4.4 GO:0030957 Tat protein binding(GO:0030957)
0.1 4.1 GO:0043014 alpha-tubulin binding(GO:0043014)
0.8 3.4 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.1 3.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.4 3.2 GO:0001972 retinoic acid binding(GO:0001972)
0.0 3.2 GO:0019955 cytokine binding(GO:0019955)
0.6 3.1 GO:0005113 patched binding(GO:0005113)
0.2 3.1 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.6 3.0 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.2 3.0 GO:0042556 cobinamide kinase activity(GO:0008819) phytol kinase activity(GO:0010276) phenol kinase activity(GO:0018720) cyclin-dependent protein kinase activating kinase regulator activity(GO:0019914) inositol tetrakisphosphate 2-kinase activity(GO:0032942) heptose 7-phosphate kinase activity(GO:0033785) aminoglycoside phosphotransferase activity(GO:0034071) eukaryotic elongation factor-2 kinase regulator activity(GO:0042556) eukaryotic elongation factor-2 kinase activator activity(GO:0042557) LPPG:FO 2-phospho-L-lactate transferase activity(GO:0043743) cytidine kinase activity(GO:0043771) glycerate 2-kinase activity(GO:0043798) (S)-lactate 2-kinase activity(GO:0043841) phosphoserine:homoserine phosphotransferase activity(GO:0043899) L-seryl-tRNA(Sec) kinase activity(GO:0043915) phosphocholine transferase activity(GO:0044605) GTP-dependent polynucleotide kinase activity(GO:0051735) farnesol kinase activity(GO:0052668) CTP:2-trans,-6-trans-farnesol kinase activity(GO:0052669) geraniol kinase activity(GO:0052670) geranylgeraniol kinase activity(GO:0052671) CTP:geranylgeraniol kinase activity(GO:0052672) prenol kinase activity(GO:0052673) 1-phosphatidylinositol-5-kinase activity(GO:0052810) 1-phosphatidylinositol-3-phosphate 4-kinase activity(GO:0052811) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835) inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.4 2.9 GO:0035174 histone serine kinase activity(GO:0035174)
0.1 2.5 GO:0031492 nucleosomal DNA binding(GO:0031492)