Motif ID: Rxrb

Z-value: 0.559


Transcription factors associated with Rxrb:

Gene SymbolEntrez IDGene Name
Rxrb ENSMUSG00000039656.10 Rxrb

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rxrbmm10_v2_chr17_+_34032071_34032196-0.462.9e-02Click!


Activity profile for motif Rxrb.

activity profile for motif Rxrb


Sorted Z-values histogram for motif Rxrb

Sorted Z-values for motif Rxrb



Network of associatons between targets according to the STRING database.



First level regulatory network of Rxrb

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_6487231 2.057 ENSMUST00000140079.1
ENSMUST00000131494.1
St18

suppression of tumorigenicity 18

chr6_-_23248264 1.904 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr1_+_74791516 1.329 ENSMUST00000006718.8
Wnt10a
wingless related MMTV integration site 10a
chr10_+_93641041 1.280 ENSMUST00000020204.4
Ntn4
netrin 4
chr11_-_40733373 0.838 ENSMUST00000020579.8
Hmmr
hyaluronan mediated motility receptor (RHAMM)
chr10_-_88146867 0.747 ENSMUST00000164121.1
ENSMUST00000164803.1
ENSMUST00000168163.1
ENSMUST00000048518.9
Parpbp



PARP1 binding protein



chr11_+_40733936 0.633 ENSMUST00000127382.1
Nudcd2
NudC domain containing 2
chr14_+_54476100 0.613 ENSMUST00000164766.1
ENSMUST00000164697.1
Rem2

rad and gem related GTP binding protein 2

chr5_+_47984571 0.602 ENSMUST00000174313.1
Slit2
slit homolog 2 (Drosophila)
chr4_-_117178726 0.592 ENSMUST00000153953.1
ENSMUST00000106436.1
Kif2c

kinesin family member 2C

chr4_+_130047914 0.575 ENSMUST00000142293.1
Col16a1
collagen, type XVI, alpha 1
chr11_+_40733639 0.534 ENSMUST00000020578.4
Nudcd2
NudC domain containing 2
chr5_+_108065742 0.474 ENSMUST00000081567.4
ENSMUST00000170319.1
ENSMUST00000112626.1
Mtf2


metal response element binding transcription factor 2


chr2_-_80128834 0.445 ENSMUST00000102654.4
ENSMUST00000102655.3
Pde1a

phosphodiesterase 1A, calmodulin-dependent

chr5_+_72914264 0.442 ENSMUST00000144843.1
Slain2
SLAIN motif family, member 2
chr4_+_148000722 0.425 ENSMUST00000103230.4
Nppa
natriuretic peptide type A
chrX_-_23365044 0.403 ENSMUST00000115313.1
Klhl13
kelch-like 13
chr1_+_146420434 0.399 ENSMUST00000163646.1
Gm5263
predicted gene 5263
chr15_+_76797628 0.396 ENSMUST00000165535.2
Gm17271
predicted gene, 17271
chr5_+_72914554 0.385 ENSMUST00000143829.1
Slain2
SLAIN motif family, member 2
chr1_+_131910458 0.383 ENSMUST00000062264.6
Nucks1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr5_+_3803160 0.375 ENSMUST00000171023.1
ENSMUST00000080085.4
Krit1

KRIT1, ankyrin repeat containing

chr5_+_110839973 0.354 ENSMUST00000066160.1
Chek2
checkpoint kinase 2
chr4_+_57845240 0.350 ENSMUST00000102903.1
ENSMUST00000107598.3
Akap2

A kinase (PRKA) anchor protein 2

chr5_+_108065696 0.332 ENSMUST00000172045.1
Mtf2
metal response element binding transcription factor 2
chr1_-_52499980 0.319 ENSMUST00000164747.1
Nab1
Ngfi-A binding protein 1
chr13_+_55209776 0.319 ENSMUST00000099490.2
Nsd1
nuclear receptor-binding SET-domain protein 1
chr12_-_98737405 0.319 ENSMUST00000170188.1
Ptpn21
protein tyrosine phosphatase, non-receptor type 21
chr16_-_30388530 0.314 ENSMUST00000100013.2
ENSMUST00000061350.6
Atp13a3

ATPase type 13A3

chr3_-_96172384 0.312 ENSMUST00000180958.1
Gm17690
predicted gene, 17690
chr4_+_130047840 0.311 ENSMUST00000044565.8
ENSMUST00000132251.1
Col16a1

collagen, type XVI, alpha 1

chr4_+_44300876 0.309 ENSMUST00000045607.5
Melk
maternal embryonic leucine zipper kinase
chr16_+_31663935 0.309 ENSMUST00000100001.3
ENSMUST00000064477.7
Dlg1

discs, large homolog 1 (Drosophila)

chr11_+_75193783 0.302 ENSMUST00000102514.3
Rtn4rl1
reticulon 4 receptor-like 1
chr16_+_31663841 0.300 ENSMUST00000115201.1
Dlg1
discs, large homolog 1 (Drosophila)
chr8_-_67910911 0.292 ENSMUST00000093468.5
Psd3
pleckstrin and Sec7 domain containing 3
chr13_+_5861489 0.290 ENSMUST00000000080.6
Klf6
Kruppel-like factor 6
chr14_+_21500879 0.285 ENSMUST00000182964.1
Kat6b
K(lysine) acetyltransferase 6B
chr5_+_137630116 0.281 ENSMUST00000175968.1
Lrch4
leucine-rich repeats and calponin homology (CH) domain containing 4
chr5_+_121795034 0.277 ENSMUST00000162327.1
Atxn2
ataxin 2
chr2_-_136387929 0.268 ENSMUST00000035264.2
ENSMUST00000077200.3
Pak7

p21 protein (Cdc42/Rac)-activated kinase 7

chr6_+_113531675 0.266 ENSMUST00000036340.5
ENSMUST00000101051.2
Fancd2

Fanconi anemia, complementation group D2

chr2_+_154548888 0.257 ENSMUST00000045116.4
ENSMUST00000109709.3
1700003F12Rik

RIKEN cDNA 1700003F12 gene

chr4_-_20778527 0.257 ENSMUST00000119374.1
Nkain3
Na+/K+ transporting ATPase interacting 3
chr12_+_109545390 0.254 ENSMUST00000146701.1
Meg3
maternally expressed 3
chr5_+_119834663 0.253 ENSMUST00000018407.6
Tbx5
T-box 5
chr5_-_123666682 0.245 ENSMUST00000149410.1
Clip1
CAP-GLY domain containing linker protein 1
chr7_+_35802593 0.244 ENSMUST00000052454.2
E130304I02Rik
RIKEN cDNA E130304I02 gene
chr7_-_4778141 0.239 ENSMUST00000094892.5
Il11
interleukin 11
chr1_+_84839833 0.236 ENSMUST00000097672.3
Fbxo36
F-box protein 36
chr7_-_35802968 0.234 ENSMUST00000061586.4
Zfp507
zinc finger protein 507
chr3_+_122729158 0.226 ENSMUST00000066728.5
Pde5a
phosphodiesterase 5A, cGMP-specific
chr8_+_72135247 0.224 ENSMUST00000003575.9
Tpm4
tropomyosin 4
chr9_-_50659780 0.219 ENSMUST00000034567.3
Dlat
dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)
chr7_+_3290553 0.218 ENSMUST00000096744.5
Myadm
myeloid-associated differentiation marker
chr10_+_81136223 0.218 ENSMUST00000048128.8
Zbtb7a
zinc finger and BTB domain containing 7a
chr5_-_74702891 0.216 ENSMUST00000117388.1
Lnx1
ligand of numb-protein X 1
chr17_+_17831004 0.215 ENSMUST00000172097.2
4930546H06Rik
RIKEN cDNA 4930546H06 gene
chr4_+_43632185 0.207 ENSMUST00000107874.2
Npr2
natriuretic peptide receptor 2
chr2_-_119477613 0.207 ENSMUST00000110808.1
ENSMUST00000049920.7
Ino80

INO80 homolog (S. cerevisiae)

chr2_-_80129458 0.201 ENSMUST00000102653.1
Pde1a
phosphodiesterase 1A, calmodulin-dependent
chr17_-_35704000 0.189 ENSMUST00000097333.3
ENSMUST00000003628.6
Ddr1

discoidin domain receptor family, member 1

chr14_+_58070547 0.182 ENSMUST00000165526.1
Fgf9
fibroblast growth factor 9
chr12_-_40223149 0.176 ENSMUST00000171553.1
ENSMUST00000001672.5
Ifrd1

interferon-related developmental regulator 1

chr14_+_20929416 0.175 ENSMUST00000022369.7
Vcl
vinculin
chr7_+_16959714 0.162 ENSMUST00000038163.6
Pnmal1
PNMA-like 1
chr11_-_50325599 0.153 ENSMUST00000179865.1
ENSMUST00000020637.8
Canx

calnexin

chr4_-_20778852 0.149 ENSMUST00000102998.3
Nkain3
Na+/K+ transporting ATPase interacting 3
chr14_-_118706180 0.148 ENSMUST00000036554.6
ENSMUST00000166646.1
Abcc4

ATP-binding cassette, sub-family C (CFTR/MRP), member 4

chr13_+_44729794 0.142 ENSMUST00000172830.1
Jarid2
jumonji, AT rich interactive domain 2
chr10_+_80148263 0.141 ENSMUST00000099492.3
ENSMUST00000042057.5
Midn

midnolin

chr4_-_41048124 0.140 ENSMUST00000030136.6
Aqp7
aquaporin 7
chr10_+_88146992 0.140 ENSMUST00000052355.7
Nup37
nucleoporin 37
chr12_+_33314277 0.134 ENSMUST00000133549.1
Atxn7l1
ataxin 7-like 1
chr18_-_80713062 0.128 ENSMUST00000170905.1
ENSMUST00000078049.4
Nfatc1

nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1

chr13_-_54688264 0.127 ENSMUST00000150626.1
ENSMUST00000134177.1
Rnf44

ring finger protein 44

chr19_-_4615453 0.124 ENSMUST00000053597.2
Lrfn4
leucine rich repeat and fibronectin type III domain containing 4
chr7_+_28440927 0.123 ENSMUST00000078845.6
Gmfg
glia maturation factor, gamma
chr12_-_111713185 0.121 ENSMUST00000054636.6
Bag5
BCL2-associated athanogene 5
chr12_-_113260217 0.117 ENSMUST00000178282.1
Igha
immunoglobulin heavy constant alpha
chr10_+_88147061 0.112 ENSMUST00000169309.1
Nup37
nucleoporin 37
chr2_+_102706356 0.112 ENSMUST00000123759.1
ENSMUST00000111212.1
ENSMUST00000005220.4
Slc1a2


solute carrier family 1 (glial high affinity glutamate transporter), member 2


chr6_+_120836201 0.104 ENSMUST00000009256.2
Bcl2l13
BCL2-like 13 (apoptosis facilitator)
chr4_-_58912678 0.096 ENSMUST00000144512.1
ENSMUST00000102889.3
ENSMUST00000055822.8
AI314180


expressed sequence AI314180


chr12_-_111712946 0.093 ENSMUST00000160825.1
ENSMUST00000162953.1
Bag5

BCL2-associated athanogene 5

chr3_+_90062781 0.093 ENSMUST00000029551.2
1700094D03Rik
RIKEN cDNA 1700094D03 gene
chr2_-_6721606 0.092 ENSMUST00000150624.2
ENSMUST00000142941.1
ENSMUST00000100429.4
ENSMUST00000182879.1
Celf2



CUGBP, Elav-like family member 2



chr10_+_127195240 0.092 ENSMUST00000181578.1
F420014N23Rik
RIKEN cDNA F420014N23 gene
chr2_+_72054598 0.089 ENSMUST00000028525.5
Rapgef4
Rap guanine nucleotide exchange factor (GEF) 4
chr5_-_134946917 0.085 ENSMUST00000051401.2
Cldn4
claudin 4
chr7_-_141434532 0.078 ENSMUST00000133021.1
ENSMUST00000106007.3
ENSMUST00000150026.1
ENSMUST00000133206.2
Slc25a22



solute carrier family 25 (mitochondrial carrier, glutamate), member 22



chr13_-_54688246 0.076 ENSMUST00000122935.1
ENSMUST00000128257.1
Rnf44

ring finger protein 44

chr11_-_70255329 0.076 ENSMUST00000108574.2
ENSMUST00000000329.2
Alox12

arachidonate 12-lipoxygenase

chr14_-_16243309 0.073 ENSMUST00000112625.1
Oxsm
3-oxoacyl-ACP synthase, mitochondrial
chr12_+_91400990 0.072 ENSMUST00000021346.7
ENSMUST00000021343.6
Tshr

thyroid stimulating hormone receptor

chr12_-_111712909 0.066 ENSMUST00000160576.1
Bag5
BCL2-associated athanogene 5
chr18_+_57142782 0.061 ENSMUST00000139892.1
Megf10
multiple EGF-like-domains 10
chr11_+_97315716 0.043 ENSMUST00000019026.3
ENSMUST00000132168.1
Mrpl45

mitochondrial ribosomal protein L45

chr1_+_86021935 0.040 ENSMUST00000052854.6
ENSMUST00000125083.1
ENSMUST00000152501.1
ENSMUST00000113344.1
ENSMUST00000130504.1
ENSMUST00000153247.2
Spata3





spermatogenesis associated 3





chr13_-_28953690 0.034 ENSMUST00000067230.5
Sox4
SRY-box containing gene 4
chr17_-_32388885 0.034 ENSMUST00000087703.5
ENSMUST00000170603.1
Wiz

widely-interspaced zinc finger motifs

chr10_+_127290774 0.032 ENSMUST00000026475.8
ENSMUST00000139091.1
Ddit3

DNA-damage inducible transcript 3

chr13_+_46669517 0.031 ENSMUST00000099547.3
C78339
expressed sequence C78339
chr10_-_128821576 0.028 ENSMUST00000026409.3
Ormdl2
ORM1-like 2 (S. cerevisiae)
chr12_+_108792946 0.025 ENSMUST00000021692.7
Yy1
YY1 transcription factor
chr19_-_6980420 0.023 ENSMUST00000070878.8
ENSMUST00000177752.1
Fkbp2

FK506 binding protein 2

chr9_+_55208925 0.022 ENSMUST00000034859.8
Fbxo22
F-box protein 22
chr11_-_29547820 0.019 ENSMUST00000102844.3
Rps27a
ribosomal protein S27A
chr2_+_151542483 0.014 ENSMUST00000044011.5
Fkbp1a
FK506 binding protein 1a
chr6_-_129533267 0.009 ENSMUST00000181594.1
1700101I11Rik
RIKEN cDNA 1700101I11 gene
chr1_-_170306332 0.007 ENSMUST00000179801.1
Gm7694
predicted gene 7694
chr3_-_94786469 0.001 ENSMUST00000107273.1
Cgn
cingulin
chr6_+_147531392 0.001 ENSMUST00000111614.2
Ccdc91
coiled-coil domain containing 91

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.9 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.3 1.3 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.2 0.6 GO:0050929 corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.2 0.8 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 0.4 GO:0097623 potassium ion export across plasma membrane(GO:0097623)
0.1 1.3 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.1 0.6 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 0.7 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 0.6 GO:1903753 cortical microtubule organization(GO:0043622) establishment of centrosome localization(GO:0051660) hard palate development(GO:0060022) negative regulation of p38MAPK cascade(GO:1903753)
0.1 0.4 GO:1903463 mitotic cell cycle phase(GO:0098763) regulation of mitotic cell cycle DNA replication(GO:1903463)
0.1 0.2 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678)
0.1 0.2 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.1 0.3 GO:0051890 regulation of cardioblast differentiation(GO:0051890)
0.0 0.3 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.2 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.1 GO:0060854 patterning of lymph vessels(GO:0060854)
0.0 0.3 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.6 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.1 GO:0015793 glycerol transport(GO:0015793)
0.0 0.3 GO:0061084 negative regulation of protein refolding(GO:0061084)
0.0 0.2 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.9 GO:0051894 integrin activation(GO:0033622) positive regulation of focal adhesion assembly(GO:0051894)
0.0 0.2 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.8 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.0 0.1 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
0.0 0.2 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.4 GO:0046628 positive regulation of insulin receptor signaling pathway(GO:0046628)
0.0 0.1 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.1 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.4 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.1 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.1 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.2 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 0.1 GO:0006855 drug transmembrane transport(GO:0006855)
0.0 0.0 GO:2000015 regulation of determination of dorsal identity(GO:2000015)
0.0 0.1 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.3 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.1 GO:0014719 skeletal muscle satellite cell activation(GO:0014719)
0.0 0.1 GO:0051790 short-chain fatty acid biosynthetic process(GO:0051790)
0.0 0.3 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.0 GO:0003289 atrial septum primum morphogenesis(GO:0003289) noradrenergic neuron differentiation(GO:0003357) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910) limb bud formation(GO:0060174)
0.0 0.1 GO:0061436 establishment of skin barrier(GO:0061436)
0.0 0.3 GO:0008340 determination of adult lifespan(GO:0008340)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 0.2 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 0.4 GO:0042629 mast cell granule(GO:0042629)
0.1 1.7 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.9 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.3 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.2 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.1 GO:0044316 cone cell pedicle(GO:0044316)
0.0 0.2 GO:0005916 fascia adherens(GO:0005916)
0.0 0.2 GO:0031011 Ino80 complex(GO:0031011)
0.0 1.5 GO:0005604 basement membrane(GO:0005604)
0.0 0.1 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.0 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.0 0.6 GO:0005581 collagen trimer(GO:0005581)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.9 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.6 GO:0097016 L27 domain binding(GO:0097016)
0.1 0.6 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.3 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.3 GO:0103116 alpha-D-galactofuranose transporter activity(GO:0103116)
0.0 0.2 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 1.3 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.3 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.4 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.1 GO:0015265 urea channel activity(GO:0015265)
0.0 0.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.2 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.1 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.0 0.3 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0001224 RNA polymerase II transcription cofactor binding(GO:0001224)
0.0 0.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.8 GO:0035064 methylated histone binding(GO:0035064)
0.0 2.3 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)