Motif ID: Zbtb16
Z-value: 1.124
Transcription factors associated with Zbtb16:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Zbtb16 | ENSMUSG00000066687.4 | Zbtb16 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Zbtb16 | mm10_v2_chr9_-_48835932_48835962 | 0.27 | 2.1e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 2.9 | GO:0090285 | negative regulation of protein glycosylation in Golgi(GO:0090285) |
| 0.5 | 2.0 | GO:0045409 | negative regulation of interleukin-6 biosynthetic process(GO:0045409) |
| 0.4 | 1.6 | GO:0010749 | regulation of nitric oxide mediated signal transduction(GO:0010749) |
| 0.4 | 1.8 | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) |
| 0.3 | 1.0 | GO:0043988 | histone H3-S28 phosphorylation(GO:0043988) |
| 0.3 | 2.3 | GO:0019370 | leukotriene biosynthetic process(GO:0019370) |
| 0.3 | 1.5 | GO:0034421 | post-translational protein acetylation(GO:0034421) |
| 0.3 | 0.9 | GO:0045819 | positive regulation of glycogen catabolic process(GO:0045819) |
| 0.3 | 1.6 | GO:0051461 | regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461) |
| 0.3 | 1.1 | GO:0046121 | deoxyribonucleoside catabolic process(GO:0046121) |
| 0.3 | 1.0 | GO:0072592 | regulation of integrin biosynthetic process(GO:0045113) oxygen metabolic process(GO:0072592) |
| 0.2 | 0.6 | GO:1902358 | sulfate transmembrane transport(GO:1902358) |
| 0.2 | 1.0 | GO:0048245 | eosinophil chemotaxis(GO:0048245) |
| 0.2 | 10.6 | GO:0035019 | somatic stem cell population maintenance(GO:0035019) |
| 0.2 | 0.5 | GO:0006546 | glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464) |
| 0.2 | 3.5 | GO:0008340 | determination of adult lifespan(GO:0008340) |
| 0.1 | 0.6 | GO:1904354 | negative regulation of telomere capping(GO:1904354) |
| 0.1 | 0.4 | GO:0050883 | musculoskeletal movement, spinal reflex action(GO:0050883) |
| 0.1 | 3.5 | GO:0010960 | magnesium ion homeostasis(GO:0010960) |
| 0.1 | 0.4 | GO:0006545 | glycine biosynthetic process(GO:0006545) |
| 0.1 | 0.5 | GO:0006297 | nucleotide-excision repair, DNA gap filling(GO:0006297) |
| 0.1 | 0.8 | GO:1903624 | regulation of apoptotic DNA fragmentation(GO:1902510) regulation of DNA catabolic process(GO:1903624) |
| 0.1 | 0.3 | GO:0021691 | cerebellar Purkinje cell layer maturation(GO:0021691) |
| 0.1 | 0.7 | GO:0006561 | proline biosynthetic process(GO:0006561) |
| 0.1 | 0.3 | GO:0032382 | positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373) positive regulation of cholesterol import(GO:1904109) positive regulation of sterol import(GO:2000911) |
| 0.1 | 1.7 | GO:0001522 | pseudouridine synthesis(GO:0001522) |
| 0.1 | 0.4 | GO:1902261 | positive regulation of delayed rectifier potassium channel activity(GO:1902261) positive regulation of voltage-gated potassium channel activity(GO:1903818) |
| 0.1 | 0.2 | GO:0031086 | nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087) |
| 0.1 | 0.4 | GO:0070562 | regulation of vitamin D receptor signaling pathway(GO:0070562) |
| 0.1 | 1.2 | GO:0010603 | regulation of cytoplasmic mRNA processing body assembly(GO:0010603) |
| 0.1 | 0.2 | GO:1902338 | apoptotic process involved in heart morphogenesis(GO:0003278) negative regulation of apoptotic process involved in morphogenesis(GO:1902338) negative regulation of apoptotic process involved in development(GO:1904746) |
| 0.1 | 0.3 | GO:0036337 | Fas signaling pathway(GO:0036337) |
| 0.1 | 0.1 | GO:0006999 | nuclear pore organization(GO:0006999) |
| 0.1 | 0.3 | GO:2000298 | regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298) |
| 0.1 | 0.3 | GO:0071883 | activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883) |
| 0.1 | 1.3 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.0 | 0.1 | GO:1902524 | positive regulation of protein K48-linked ubiquitination(GO:1902524) |
| 0.0 | 0.4 | GO:0015838 | amino-acid betaine transport(GO:0015838) |
| 0.0 | 0.4 | GO:0006370 | 7-methylguanosine mRNA capping(GO:0006370) |
| 0.0 | 0.2 | GO:0009162 | deoxyribonucleoside monophosphate metabolic process(GO:0009162) |
| 0.0 | 0.3 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
| 0.0 | 0.1 | GO:0035063 | nuclear speck organization(GO:0035063) |
| 0.0 | 0.3 | GO:0090315 | negative regulation of protein targeting to membrane(GO:0090315) |
| 0.0 | 0.3 | GO:0045040 | protein import into mitochondrial outer membrane(GO:0045040) |
| 0.0 | 0.5 | GO:0032463 | negative regulation of protein homooligomerization(GO:0032463) |
| 0.0 | 5.0 | GO:0010466 | negative regulation of peptidase activity(GO:0010466) |
| 0.0 | 0.3 | GO:0061158 | 3'-UTR-mediated mRNA destabilization(GO:0061158) |
| 0.0 | 1.8 | GO:0008631 | intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631) |
| 0.0 | 1.2 | GO:1902476 | chloride transmembrane transport(GO:1902476) |
| 0.0 | 0.1 | GO:0006203 | dGTP catabolic process(GO:0006203) |
| 0.0 | 0.2 | GO:0045162 | clustering of voltage-gated sodium channels(GO:0045162) |
| 0.0 | 0.3 | GO:0018206 | peptidyl-methionine modification(GO:0018206) |
| 0.0 | 0.8 | GO:0007638 | mechanosensory behavior(GO:0007638) |
| 0.0 | 0.1 | GO:1905065 | positive regulation of vascular smooth muscle cell differentiation(GO:1905065) |
| 0.0 | 2.4 | GO:0072332 | intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332) |
| 0.0 | 0.1 | GO:0048539 | bone marrow development(GO:0048539) |
| 0.0 | 0.8 | GO:0045103 | intermediate filament-based process(GO:0045103) |
| 0.0 | 0.2 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
| 0.0 | 0.0 | GO:0019805 | quinolinate biosynthetic process(GO:0019805) |
| 0.0 | 0.1 | GO:0009235 | cobalamin metabolic process(GO:0009235) |
| 0.0 | 0.1 | GO:0090400 | stress-induced premature senescence(GO:0090400) |
| 0.0 | 0.3 | GO:0044872 | lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872) |
| 0.0 | 0.8 | GO:0009214 | cyclic nucleotide catabolic process(GO:0009214) |
| 0.0 | 0.1 | GO:0090611 | ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611) positive regulation of extracellular exosome assembly(GO:1903553) |
| 0.0 | 0.6 | GO:0006826 | iron ion transport(GO:0006826) |
| 0.0 | 0.2 | GO:2000741 | positive regulation of mesenchymal stem cell differentiation(GO:2000741) |
| 0.0 | 0.3 | GO:0016926 | protein desumoylation(GO:0016926) |
| 0.0 | 0.1 | GO:0045602 | negative regulation of endothelial cell differentiation(GO:0045602) |
| 0.0 | 0.0 | GO:0006691 | leukotriene metabolic process(GO:0006691) |
| 0.0 | 0.2 | GO:0010388 | protein deneddylation(GO:0000338) cullin deneddylation(GO:0010388) |
| 0.0 | 0.2 | GO:0048240 | sperm capacitation(GO:0048240) |
| 0.0 | 0.1 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
| 0.0 | 0.2 | GO:0000479 | endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479) |
| 0.0 | 0.5 | GO:0003341 | cilium movement(GO:0003341) |
| 0.0 | 0.1 | GO:0006183 | GTP biosynthetic process(GO:0006183) |
| 0.0 | 0.1 | GO:0030539 | male genitalia development(GO:0030539) |
| 0.0 | 0.1 | GO:2001181 | positive regulation of interleukin-10 secretion(GO:2001181) |
| 0.0 | 0.1 | GO:2000381 | negative regulation of mesoderm development(GO:2000381) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 1.6 | GO:0017071 | intracellular cyclic nucleotide activated cation channel complex(GO:0017071) |
| 0.3 | 1.1 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
| 0.2 | 1.5 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
| 0.2 | 1.0 | GO:0032133 | chromosome passenger complex(GO:0032133) |
| 0.2 | 0.9 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
| 0.1 | 0.8 | GO:0035749 | myelin sheath adaxonal region(GO:0035749) |
| 0.1 | 0.6 | GO:0030870 | Mre11 complex(GO:0030870) |
| 0.1 | 0.5 | GO:0008622 | epsilon DNA polymerase complex(GO:0008622) |
| 0.1 | 0.3 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
| 0.1 | 1.0 | GO:0031045 | dense core granule(GO:0031045) |
| 0.1 | 0.4 | GO:0005726 | perichromatin fibrils(GO:0005726) |
| 0.1 | 0.2 | GO:0036128 | CatSper complex(GO:0036128) |
| 0.1 | 1.8 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.1 | 0.2 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
| 0.1 | 0.4 | GO:0070552 | BRISC complex(GO:0070552) |
| 0.1 | 2.8 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.0 | 1.2 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.0 | 0.2 | GO:0070032 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) |
| 0.0 | 0.3 | GO:0031315 | extrinsic component of mitochondrial outer membrane(GO:0031315) |
| 0.0 | 0.3 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
| 0.0 | 0.5 | GO:0005922 | connexon complex(GO:0005922) |
| 0.0 | 0.2 | GO:0071014 | post-mRNA release spliceosomal complex(GO:0071014) |
| 0.0 | 0.3 | GO:0035869 | ciliary transition zone(GO:0035869) |
| 0.0 | 0.5 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.0 | 0.4 | GO:0071004 | U2-type prespliceosome(GO:0071004) |
| 0.0 | 0.3 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.0 | 0.2 | GO:0071439 | clathrin complex(GO:0071439) |
| 0.0 | 0.0 | GO:0008282 | ATP-sensitive potassium channel complex(GO:0008282) |
| 0.0 | 0.1 | GO:0044615 | nuclear pore nuclear basket(GO:0044615) |
| 0.0 | 0.9 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.0 | 0.9 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.0 | 0.1 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
| 0.0 | 1.0 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.0 | 0.3 | GO:0045334 | clathrin-coated endocytic vesicle(GO:0045334) |
| 0.0 | 0.1 | GO:0045261 | mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 2.9 | GO:0071633 | dihydroceramidase activity(GO:0071633) |
| 0.4 | 1.5 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
| 0.3 | 1.0 | GO:0030171 | voltage-gated proton channel activity(GO:0030171) |
| 0.3 | 1.6 | GO:0005052 | peroxisome matrix targeting signal-1 binding(GO:0005052) |
| 0.3 | 0.9 | GO:0000402 | open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402) |
| 0.2 | 2.3 | GO:0016755 | transferase activity, transferring amino-acyl groups(GO:0016755) |
| 0.2 | 0.7 | GO:0004735 | pyrroline-5-carboxylate reductase activity(GO:0004735) |
| 0.1 | 1.0 | GO:0035174 | histone serine kinase activity(GO:0035174) |
| 0.1 | 0.4 | GO:0008732 | threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732) |
| 0.1 | 1.7 | GO:0034951 | pivalyl-CoA mutase activity(GO:0034784) o-hydroxylaminobenzoate mutase activity(GO:0034951) lupeol synthase activity(GO:0042299) beta-amyrin synthase activity(GO:0042300) baruol synthase activity(GO:0080011) |
| 0.1 | 1.8 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.1 | 2.0 | GO:0001871 | pattern binding(GO:0001871) polysaccharide binding(GO:0030247) |
| 0.1 | 5.0 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.1 | 1.1 | GO:0016832 | aldehyde-lyase activity(GO:0016832) |
| 0.1 | 0.4 | GO:0097642 | calcitonin family receptor activity(GO:0097642) |
| 0.1 | 1.0 | GO:0050692 | DBD domain binding(GO:0050692) |
| 0.1 | 0.3 | GO:0004556 | alpha-amylase activity(GO:0004556) |
| 0.1 | 0.3 | GO:0005093 | Rab GDP-dissociation inhibitor activity(GO:0005093) |
| 0.1 | 0.3 | GO:0033814 | propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121) |
| 0.1 | 1.2 | GO:0031404 | chloride ion binding(GO:0031404) |
| 0.1 | 0.3 | GO:0000293 | ferric-chelate reductase activity(GO:0000293) |
| 0.1 | 0.4 | GO:0098518 | polynucleotide phosphatase activity(GO:0098518) |
| 0.1 | 3.5 | GO:0000049 | tRNA binding(GO:0000049) |
| 0.1 | 0.4 | GO:0034056 | estrogen response element binding(GO:0034056) |
| 0.1 | 0.6 | GO:0008271 | secondary active sulfate transmembrane transporter activity(GO:0008271) |
| 0.0 | 1.0 | GO:0042056 | chemoattractant activity(GO:0042056) |
| 0.0 | 0.3 | GO:0032184 | SUMO polymer binding(GO:0032184) |
| 0.0 | 1.8 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.0 | 1.2 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.0 | 0.4 | GO:0050733 | RS domain binding(GO:0050733) |
| 0.0 | 0.5 | GO:0005243 | gap junction channel activity(GO:0005243) |
| 0.0 | 0.3 | GO:0015266 | protein channel activity(GO:0015266) |
| 0.0 | 0.9 | GO:0017025 | TBP-class protein binding(GO:0017025) |
| 0.0 | 0.1 | GO:0031871 | proteinase activated receptor binding(GO:0031871) |
| 0.0 | 0.7 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.0 | 0.3 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.0 | 0.2 | GO:0001226 | RNA polymerase II transcription corepressor binding(GO:0001226) |
| 0.0 | 0.2 | GO:0034511 | U3 snoRNA binding(GO:0034511) |
| 0.0 | 0.5 | GO:0016594 | glycine binding(GO:0016594) |
| 0.0 | 0.4 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.0 | 1.6 | GO:0005179 | hormone activity(GO:0005179) |
| 0.0 | 1.3 | GO:0004112 | cyclic-nucleotide phosphodiesterase activity(GO:0004112) |
| 0.0 | 0.3 | GO:0070636 | single-strand selective uracil DNA N-glycosylase activity(GO:0017065) nicotinamide riboside hydrolase activity(GO:0070635) nicotinic acid riboside hydrolase activity(GO:0070636) deoxyribonucleoside 5'-monophosphate N-glycosidase activity(GO:0070694) |
| 0.0 | 0.4 | GO:0016208 | AMP binding(GO:0016208) |
| 0.0 | 0.9 | GO:0097472 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472) |
| 0.0 | 0.3 | GO:0016929 | SUMO-specific protease activity(GO:0016929) |
| 0.0 | 0.4 | GO:0017160 | Ral GTPase binding(GO:0017160) |
| 0.0 | 0.2 | GO:0008301 | DNA binding, bending(GO:0008301) |
| 0.0 | 0.0 | GO:0016175 | superoxide-generating NADPH oxidase activity(GO:0016175) |
| 0.0 | 0.1 | GO:0051377 | mannose-ethanolamine phosphotransferase activity(GO:0051377) |
| 0.0 | 0.2 | GO:0008641 | small protein activating enzyme activity(GO:0008641) |
| 0.0 | 0.4 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.0 | 0.6 | GO:0003684 | damaged DNA binding(GO:0003684) |
| 0.0 | 0.8 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
| 0.0 | 0.6 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
