Motif ID: Tfeb_Usf1_Srebf1_Usf2_Bhlhe41_Srebf2

Z-value: 1.077

Transcription factors associated with Tfeb_Usf1_Srebf1_Usf2_Bhlhe41_Srebf2:

Gene SymbolEntrez IDGene Name
Bhlhe41 ENSMUSG00000030256.5 Bhlhe41
Srebf1 ENSMUSG00000020538.9 Srebf1
Srebf2 ENSMUSG00000022463.7 Srebf2
Tfeb ENSMUSG00000023990.12 Tfeb
Usf1 ENSMUSG00000026641.7 Usf1
Usf2 ENSMUSG00000058239.7 Usf2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Usf2mm10_v2_chr7_-_30956742_30956803-0.702.3e-04Click!
Usf1mm10_v2_chr1_+_171411343_171411384-0.692.4e-04Click!
Tfebmm10_v2_chr17_+_47785720_477857390.406.1e-02Click!
Srebf2mm10_v2_chr15_+_82147238_82147275-0.331.2e-01Click!
Srebf1mm10_v2_chr11_-_60220550_602206320.331.2e-01Click!


Activity profile for motif Tfeb_Usf1_Srebf1_Usf2_Bhlhe41_Srebf2.

activity profile for motif Tfeb_Usf1_Srebf1_Usf2_Bhlhe41_Srebf2


Sorted Z-values histogram for motif Tfeb_Usf1_Srebf1_Usf2_Bhlhe41_Srebf2

Sorted Z-values for motif Tfeb_Usf1_Srebf1_Usf2_Bhlhe41_Srebf2



Network of associatons between targets according to the STRING database.



First level regulatory network of Tfeb_Usf1_Srebf1_Usf2_Bhlhe41_Srebf2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_34882919 4.857 ENSMUST00000098163.2
ENSMUST00000047950.5
 Zfp292

zinc finger protein 292

chr3_-_89773221 4.332 ENSMUST00000038450.1
 4632404H12Rik
RIKEN cDNA 4632404H12 gene
chr10_+_41519493 4.295 ENSMUST00000019962.8
 Cd164
CD164 antigen
chr4_+_127077374 3.624 ENSMUST00000046751.6
ENSMUST00000094713.3
 Zmym6

zinc finger, MYM-type 6

chr9_-_87255536 3.595 ENSMUST00000093802.4
 4922501C03Rik
RIKEN cDNA 4922501C03 gene
chrX_+_81070646 3.395 ENSMUST00000171953.1
ENSMUST00000026760.2
 Tmem47

transmembrane protein 47

chr12_-_101958148 3.368 ENSMUST00000159883.1
ENSMUST00000160251.1
ENSMUST00000161011.1
ENSMUST00000021606.5
 Atxn3



ataxin 3



chr2_-_79456750 3.344 ENSMUST00000041099.4
 Neurod1
neurogenic differentiation 1
chr10_-_63339023 3.309 ENSMUST00000177694.1
ENSMUST00000020257.6
ENSMUST00000105442.2
 Sirt1


sirtuin 1


chr15_+_66577536 3.146 ENSMUST00000048188.8
 Phf20l1
PHD finger protein 20-like 1
chr15_-_3995708 3.089 ENSMUST00000046633.8
 AW549877
expressed sequence AW549877
chr17_-_66077022 3.030 ENSMUST00000150766.1
ENSMUST00000038116.5
 Ankrd12

ankyrin repeat domain 12

chr10_+_128909866 3.022 ENSMUST00000026407.7
 Cd63
CD63 antigen
chrX_-_134600976 2.936 ENSMUST00000033621.6
 Gla
galactosidase, alpha
chr5_+_64803513 2.883 ENSMUST00000165536.1
 Klf3
Kruppel-like factor 3 (basic)
chr5_-_124425907 2.865 ENSMUST00000065263.5
 Sbno1
sno, strawberry notch homolog 1 (Drosophila)
chr2_-_126876117 2.764 ENSMUST00000028843.5
 Trpm7
transient receptor potential cation channel, subfamily M, member 7
chr2_-_126876209 2.727 ENSMUST00000103224.3
 Trpm7
transient receptor potential cation channel, subfamily M, member 7
chr17_+_26715644 2.699 ENSMUST00000062519.7
ENSMUST00000144221.1
ENSMUST00000142539.1
ENSMUST00000151681.1
 Crebrf



CREB3 regulatory factor



chr1_-_66817536 2.679 ENSMUST00000068168.3
ENSMUST00000113987.1
 Kansl1l

KAT8 regulatory NSL complex subunit 1-like


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 329 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 9.4 GO:0008643 carbohydrate transport(GO:0008643)
1.4 5.5 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
1.6 4.7 GO:1901254 positive regulation of intracellular transport of viral material(GO:1901254)
0.1 4.7 GO:0007628 adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.1 4.6 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.3 4.5 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.1 4.4 GO:0007492 endoderm development(GO:0007492)
0.1 4.3 GO:0002011 morphogenesis of an epithelial sheet(GO:0002011)
0.3 3.7 GO:0034453 microtubule anchoring(GO:0034453)
1.2 3.6 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
1.2 3.6 GO:0051542 elastin biosynthetic process(GO:0051542)
0.2 3.5 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.3 3.4 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.1 3.4 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.1 3.4 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
1.1 3.3 GO:1901420 negative regulation of response to alcohol(GO:1901420) positive regulation of macrophage apoptotic process(GO:2000111)
0.8 3.3 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
1.0 3.0 GO:0002447 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308) regulation of eosinophil activation(GO:1902566)
0.6 3.0 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.2 2.8 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 156 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 5.5 GO:0043196 varicosity(GO:0043196)
1.6 4.7 GO:0042025 viral replication complex(GO:0019034) host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
0.7 4.6 GO:0097422 tubular endosome(GO:0097422)
0.1 3.8 GO:0031526 brush border membrane(GO:0031526)
0.5 3.6 GO:0033503 HULC complex(GO:0033503)
0.4 3.6 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.2 3.5 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.2 3.3 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 3.2 GO:0000139 Golgi membrane(GO:0000139)
0.6 3.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 3.1 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.8 3.0 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.4 3.0 GO:0000322 storage vacuole(GO:0000322)
0.7 2.9 GO:0031084 BLOC-2 complex(GO:0031084)
0.6 2.9 GO:0000798 nuclear cohesin complex(GO:0000798) nuclear meiotic cohesin complex(GO:0034991)
0.2 2.9 GO:0016589 NURF complex(GO:0016589)
0.5 2.7 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 2.5 GO:0030904 retromer complex(GO:0030904)
0.1 2.4 GO:0010369 chromocenter(GO:0010369)
0.1 2.4 GO:0000242 pericentriolar material(GO:0000242)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 231 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 15.8 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.4 8.1 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.1 7.4 GO:0008565 protein transporter activity(GO:0008565)
0.1 5.3 GO:0017022 myosin binding(GO:0017022)
1.0 4.8 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 4.1 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.1 3.9 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 3.7 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 3.7 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 3.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
1.2 3.6 GO:0004008 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.0 3.6 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.7 3.4 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
1.1 3.3 GO:0046969 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.0 3.3 GO:0008083 growth factor activity(GO:0008083)
0.3 3.1 GO:0015215 nucleotide transmembrane transporter activity(GO:0015215)
0.8 3.0 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1 2.9 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.5 2.8 GO:0016936 galactoside binding(GO:0016936)
0.4 2.8 GO:0031419 cobalamin binding(GO:0031419)