Motif ID: Elf3

Z-value: 0.835


Transcription factors associated with Elf3:

Gene SymbolEntrez IDGene Name
Elf3 ENSMUSG00000003051.7 Elf3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Elf3mm10_v2_chr1_-_135258449_1352584720.232.8e-01Click!


Activity profile for motif Elf3.

activity profile for motif Elf3


Sorted Z-values histogram for motif Elf3

Sorted Z-values for motif Elf3



Network of associatons between targets according to the STRING database.



First level regulatory network of Elf3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_53159885 2.676 ENSMUST00000030010.3
 Abca1
ATP-binding cassette, sub-family A (ABC1), member 1
chrX_+_169685191 2.505 ENSMUST00000112104.1
ENSMUST00000112107.1
 Mid1

midline 1

chr5_+_17574268 2.330 ENSMUST00000030568.7
 Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr11_-_55419898 2.117 ENSMUST00000108858.1
ENSMUST00000141530.1
 Sparc

secreted acidic cysteine rich glycoprotein

chr10_-_83648713 2.013 ENSMUST00000020500.7
 Appl2
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr11_+_115163333 1.768 ENSMUST00000021077.3
 Slc9a3r1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr11_+_61653259 1.695 ENSMUST00000004959.2
 Grap
GRB2-related adaptor protein
chr14_-_70207637 1.649 ENSMUST00000022682.5
 Sorbs3
sorbin and SH3 domain containing 3
chr4_-_118489755 1.622 ENSMUST00000184261.1
 Tie1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr19_+_5740885 1.608 ENSMUST00000081496.5
 Ltbp3
latent transforming growth factor beta binding protein 3
chr7_-_142666816 1.561 ENSMUST00000105935.1
 Igf2
insulin-like growth factor 2
chr1_-_128592284 1.547 ENSMUST00000052172.6
ENSMUST00000142893.1
 Cxcr4

chemokine (C-X-C motif) receptor 4

chr6_-_48708206 1.291 ENSMUST00000119315.1
ENSMUST00000053661.4
 Gimap6

GTPase, IMAP family member 6

chr13_+_13437602 1.249 ENSMUST00000005532.7
 Nid1
nidogen 1
chr17_+_86753900 1.186 ENSMUST00000024954.9
 Epas1
endothelial PAS domain protein 1
chr3_-_84582476 1.183 ENSMUST00000107687.2
ENSMUST00000098990.3
 Arfip1

ADP-ribosylation factor interacting protein 1

chr16_+_92498122 1.104 ENSMUST00000023670.3
 Clic6
chloride intracellular channel 6
chr14_+_80000292 1.095 ENSMUST00000088735.3
 Olfm4
olfactomedin 4
chr5_-_43981757 1.093 ENSMUST00000061299.7
 Fgfbp1
fibroblast growth factor binding protein 1
chr14_-_57890242 1.088 ENSMUST00000089473.3
 Zdhhc20
zinc finger, DHHC domain containing 20

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 100 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 2.7 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489) platelet dense granule organization(GO:0060155)
0.1 2.6 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.3 2.3 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 2.1 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.6 1.8 GO:0042939 renal sodium ion transport(GO:0003096) glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.1 1.8 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.5 1.6 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.5 1.6 GO:2000564 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124) CD8-positive, alpha-beta T cell proliferation(GO:0035740) negative regulation of regulatory T cell differentiation(GO:0045590) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.2 1.6 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 1.6 GO:0045026 plasma membrane fusion(GO:0045026)
0.0 1.6 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.5 1.5 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.4 1.5 GO:0070425 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433)
0.3 1.2 GO:1903181 regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181)
0.1 1.2 GO:0032836 glomerular basement membrane development(GO:0032836)
0.1 1.2 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.1 1.1 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 1.1 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.2 1.0 GO:0010046 arginine biosynthetic process(GO:0006526) response to mycotoxin(GO:0010046)
0.2 1.0 GO:0003430 tolerance induction to self antigen(GO:0002513) growth plate cartilage chondrocyte growth(GO:0003430)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 40 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.9 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 2.7 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.5 2.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 2.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.4 1.8 GO:0032426 stereocilium tip(GO:0032426)
0.2 1.8 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 1.2 GO:0005605 basal lamina(GO:0005605)
0.1 1.1 GO:0042581 specific granule(GO:0042581)
0.1 1.0 GO:0070852 cell body fiber(GO:0070852)
0.0 1.0 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.3 0.9 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.1 0.6 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.6 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.6 GO:0071203 WASH complex(GO:0071203)
0.0 0.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.5 GO:0005861 troponin complex(GO:0005861)
0.1 0.5 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.5 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.4 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.4 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 77 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.9 2.7 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188)
0.2 2.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 2.3 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 2.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 2.1 GO:0050840 extracellular matrix binding(GO:0050840)
0.2 1.8 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.1 1.6 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.5 1.5 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.4 1.5 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 1.5 GO:0030957 Tat protein binding(GO:0030957)
0.2 1.2 GO:0043237 laminin-1 binding(GO:0043237)
0.1 1.2 GO:0050897 cobalt ion binding(GO:0050897)
0.1 1.2 GO:0017166 vinculin binding(GO:0017166)
0.4 1.1 GO:0031750 D3 dopamine receptor binding(GO:0031750)
0.0 1.1 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 1.1 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 1.1 GO:0045296 cadherin binding(GO:0045296)
0.2 1.0 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 1.0 GO:0015643 toxic substance binding(GO:0015643)
0.1 1.0 GO:0070006 metalloaminopeptidase activity(GO:0070006)