Motif ID: Gsx2_Hoxd3_Vax1

Z-value: 0.451

Transcription factors associated with Gsx2_Hoxd3_Vax1:

Gene SymbolEntrez IDGene Name
Gsx2 ENSMUSG00000035946.6 Gsx2
Hoxd3 ENSMUSG00000079277.3 Hoxd3
Vax1 ENSMUSG00000006270.6 Vax1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Vax1mm10_v2_chr19_-_59170978_591709780.321.4e-01Click!
Gsx2mm10_v2_chr5_+_75075464_750756010.281.9e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Gsx2_Hoxd3_Vax1

PNG image of the network

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Top targets:


Showing 1 to 20 of 147 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_116067213 2.245 ENSMUST00000152412.1
G630016G05Rik
RIKEN cDNA G630016G05 gene
chr15_-_8710734 2.120 ENSMUST00000005493.7
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr15_-_8710409 1.853 ENSMUST00000157065.1
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr2_-_116067391 1.410 ENSMUST00000140185.1
2700033N17Rik
RIKEN cDNA 2700033N17 gene
chr9_-_90255927 1.331 ENSMUST00000144646.1
Tbc1d2b
TBC1 domain family, member 2B
chr5_-_62766153 1.205 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr3_+_66219909 1.123 ENSMUST00000029421.5
Ptx3
pentraxin related gene
chr2_+_109917639 0.879 ENSMUST00000046548.7
ENSMUST00000111037.2
Lgr4

leucine-rich repeat-containing G protein-coupled receptor 4

chr8_+_66386292 0.594 ENSMUST00000039540.5
ENSMUST00000110253.2
March1

membrane-associated ring finger (C3HC4) 1

chr19_+_55895508 0.560 ENSMUST00000111646.1
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr15_+_25773985 0.557 ENSMUST00000125667.1
Myo10
myosin X
chr3_+_5218516 0.531 ENSMUST00000175866.1
Zfhx4
zinc finger homeodomain 4
chr4_-_42661893 0.525 ENSMUST00000108006.3
Il11ra2
interleukin 11 receptor, alpha chain 2
chr15_+_98571004 0.474 ENSMUST00000023728.6
4930415O20Rik
RIKEN cDNA 4930415O20 gene
chr13_-_97747399 0.456 ENSMUST00000144993.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr2_-_160619971 0.430 ENSMUST00000109473.1
Gm14221
predicted gene 14221
chr8_-_34965631 0.401 ENSMUST00000033929.4
Tnks
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr6_-_54566484 0.387 ENSMUST00000019268.4
Scrn1
secernin 1
chr13_-_97747373 0.377 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr14_-_100149764 0.372 ENSMUST00000097079.4
Klf12
Kruppel-like factor 12

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 34 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.0 4.0 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 1.3 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.4 1.1 GO:0008228 opsonization(GO:0008228) modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.3 0.9 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.1 0.6 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.6 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1 0.4 GO:1904742 protein poly-ADP-ribosylation(GO:0070212) regulation of telomeric DNA binding(GO:1904742)
0.0 0.4 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.1 0.3 GO:0097212 lysosomal membrane organization(GO:0097212)
0.1 0.3 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.0 0.3 GO:0048199 vesicle targeting, to, from or within Golgi(GO:0048199)
0.0 0.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 0.2 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.1 0.2 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.1 0.2 GO:0009193 pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048)
0.0 0.2 GO:0030091 protein repair(GO:0030091)
0.0 0.2 GO:0032512 regulation of protein phosphatase type 2B activity(GO:0032512) positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0 0.2 GO:0097460 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import into cell(GO:0097460)
0.0 0.2 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)

Gene overrepresentation in cellular_component category:

Showing 1 to 9 of 9 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 4.0 GO:0043205 fibril(GO:0043205)
0.0 0.7 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.6 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.3 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.3 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.2 GO:0097433 dense body(GO:0097433)
0.0 0.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.1 GO:0097454 Schwann cell microvillus(GO:0097454)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 25 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 4.0 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 1.2 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.2 1.1 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.9 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.6 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 0.4 GO:0005118 sevenless binding(GO:0005118)
0.0 0.4 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.3 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.3 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.3 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.3 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.2 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.0 0.2 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.0 0.2 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.2 GO:0043495 protein anchor(GO:0043495)
0.0 0.2 GO:0016594 glycine binding(GO:0016594)
0.0 0.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)