Motif ID: Stat1

Z-value: 0.543


Transcription factors associated with Stat1:

Gene SymbolEntrez IDGene Name
Stat1 ENSMUSG00000026104.8 Stat1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Stat1mm10_v2_chr1_+_52119438_521194990.029.3e-01Click!


Activity profile for motif Stat1.

activity profile for motif Stat1


Sorted Z-values histogram for motif Stat1

Sorted Z-values for motif Stat1



Network of associatons between targets according to the STRING database.



First level regulatory network of Stat1

PNG image of the network

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Top targets:


Showing 1 to 20 of 162 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_+_78499087 2.330 ENSMUST00000017488.4
Vtn
vitronectin
chr3_-_80802789 1.811 ENSMUST00000107745.1
ENSMUST00000075316.4
Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr7_-_78577771 1.439 ENSMUST00000039438.7
Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
chr2_+_25180737 1.274 ENSMUST00000104999.2
Nrarp
Notch-regulated ankyrin repeat protein
chr6_+_115134899 1.205 ENSMUST00000009538.5
ENSMUST00000169345.1
Syn2

synapsin II

chr11_+_101245996 1.189 ENSMUST00000129680.1
Ramp2
receptor (calcitonin) activity modifying protein 2
chr4_-_108032069 0.950 ENSMUST00000106709.2
Podn
podocan
chr4_-_108031938 0.890 ENSMUST00000106708.1
Podn
podocan
chr4_-_64046925 0.863 ENSMUST00000107377.3
Tnc
tenascin C
chr19_+_38481057 0.858 ENSMUST00000182481.1
Plce1
phospholipase C, epsilon 1
chr15_-_93519499 0.836 ENSMUST00000109255.2
Prickle1
prickle homolog 1 (Drosophila)
chr9_-_96719404 0.824 ENSMUST00000140121.1
Zbtb38
zinc finger and BTB domain containing 38
chr9_-_96719549 0.761 ENSMUST00000128269.1
Zbtb38
zinc finger and BTB domain containing 38
chr17_-_45592569 0.744 ENSMUST00000163492.1
Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr7_+_82335732 0.735 ENSMUST00000173287.1
Adamtsl3
ADAMTS-like 3
chr8_-_105568298 0.710 ENSMUST00000005849.5
Agrp
agouti related protein
chr17_-_45592485 0.710 ENSMUST00000166119.1
Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr4_+_11704439 0.709 ENSMUST00000108304.2
Gem
GTP binding protein (gene overexpressed in skeletal muscle)
chr11_-_98729374 0.678 ENSMUST00000126565.1
ENSMUST00000100500.2
ENSMUST00000017354.6
Med24


mediator complex subunit 24


chr10_-_78591945 0.678 ENSMUST00000040580.6
Syde1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 55 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.0 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.2 2.3 GO:0097421 liver regeneration(GO:0097421)
0.1 1.8 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.2 1.5 GO:0015862 uridine transport(GO:0015862)
0.5 1.4 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.2 1.4 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.1 1.3 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 1.2 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 1.2 GO:0034340 response to type I interferon(GO:0034340)
0.2 0.9 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.1 0.9 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.9 GO:0032835 glomerulus development(GO:0032835)
0.3 0.8 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892)
0.1 0.8 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.8 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.0 0.8 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.1 0.7 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 0.7 GO:0016081 synaptic vesicle docking(GO:0016081)
0.1 0.7 GO:0010748 negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.0 0.7 GO:0051310 metaphase plate congression(GO:0051310)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 3.0 GO:0005796 Golgi lumen(GO:0005796)
0.1 1.8 GO:0032279 asymmetric synapse(GO:0032279)
0.0 1.8 GO:0072562 blood microparticle(GO:0072562)
0.0 1.2 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 0.9 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.8 GO:0005581 collagen trimer(GO:0005581)
0.0 0.7 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.7 GO:0051233 spindle midzone(GO:0051233)
0.1 0.6 GO:0042825 TAP complex(GO:0042825)
0.0 0.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.6 GO:0030673 axolemma(GO:0030673)
0.0 0.6 GO:0016592 mediator complex(GO:0016592)
0.2 0.5 GO:0031251 PAN complex(GO:0031251)
0.0 0.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 0.4 GO:0031673 H zone(GO:0031673)
0.1 0.3 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 0.3 GO:0060187 cell pole(GO:0060187)
0.0 0.3 GO:0000322 storage vacuole(GO:0000322)
0.0 0.2 GO:1902636 kinociliary basal body(GO:1902636)
0.0 0.2 GO:0097433 dense body(GO:0097433)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 41 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.3 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.3 1.8 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 1.8 GO:0005518 collagen binding(GO:0005518)
0.1 1.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 1.5 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.3 1.4 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.3 1.1 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 1.0 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.2 0.9 GO:0019962 interferon receptor activity(GO:0004904) type I interferon receptor activity(GO:0004905) type I interferon binding(GO:0019962) interleukin-20 binding(GO:0042015)
0.2 0.9 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 0.9 GO:0045545 syndecan binding(GO:0045545)
0.1 0.9 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.9 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.3 0.8 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.7 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.7 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.7 GO:0019003 GDP binding(GO:0019003)
0.2 0.6 GO:0023029 peptide antigen-transporting ATPase activity(GO:0015433) MHC class Ib protein binding(GO:0023029) tapasin binding(GO:0046980)
0.1 0.6 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)