Motif ID: Mecp2
Z-value: 1.139
Transcription factors associated with Mecp2:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Mecp2 | ENSMUSG00000031393.10 | Mecp2 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Mecp2 | mm10_v2_chrX_-_74085586_74085652 | 0.59 | 3.0e-03 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 877 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 5.0 | GO:0060059 | embryonic retina morphogenesis in camera-type eye(GO:0060059) |
| 0.7 | 3.4 | GO:0010991 | negative regulation of SMAD protein complex assembly(GO:0010991) |
| 1.1 | 3.3 | GO:0090271 | positive regulation of fibroblast growth factor production(GO:0090271) |
| 0.3 | 3.1 | GO:0042118 | endothelial cell activation(GO:0042118) |
| 0.6 | 3.0 | GO:0042997 | negative regulation of Golgi to plasma membrane protein transport(GO:0042997) |
| 0.0 | 3.0 | GO:0050775 | positive regulation of dendrite morphogenesis(GO:0050775) |
| 0.1 | 2.9 | GO:0060749 | mammary gland alveolus development(GO:0060749) mammary gland lobule development(GO:0061377) |
| 0.3 | 2.8 | GO:0055003 | cardiac myofibril assembly(GO:0055003) |
| 0.2 | 2.8 | GO:0032793 | positive regulation of CREB transcription factor activity(GO:0032793) |
| 0.1 | 2.7 | GO:0030866 | cortical actin cytoskeleton organization(GO:0030866) |
| 0.2 | 2.4 | GO:0034773 | histone H4-K20 trimethylation(GO:0034773) |
| 0.1 | 2.3 | GO:0097062 | dendritic spine maintenance(GO:0097062) |
| 0.1 | 2.3 | GO:0003281 | ventricular septum development(GO:0003281) |
| 0.2 | 2.1 | GO:0071679 | commissural neuron axon guidance(GO:0071679) |
| 0.7 | 2.0 | GO:0060489 | establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105) orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) |
| 0.1 | 2.0 | GO:0097094 | craniofacial suture morphogenesis(GO:0097094) |
| 0.6 | 1.9 | GO:0048352 | neural plate mediolateral regionalization(GO:0021998) mesoderm structural organization(GO:0048338) paraxial mesoderm structural organization(GO:0048352) |
| 0.5 | 1.9 | GO:0021564 | glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564) |
| 0.4 | 1.9 | GO:0015788 | UDP-N-acetylglucosamine transport(GO:0015788) |
| 0.2 | 1.9 | GO:0051534 | negative regulation of NFAT protein import into nucleus(GO:0051534) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 289 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 9.5 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.1 | 5.4 | GO:0016605 | PML body(GO:0016605) |
| 0.0 | 4.3 | GO:0030136 | clathrin-coated vesicle(GO:0030136) |
| 0.0 | 4.3 | GO:0045121 | membrane raft(GO:0045121) membrane microdomain(GO:0098857) |
| 0.1 | 2.8 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.0 | 2.7 | GO:0005901 | caveola(GO:0005901) |
| 0.1 | 2.6 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.1 | 2.4 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
| 0.1 | 2.2 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
| 0.0 | 2.2 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.2 | 2.1 | GO:0016342 | catenin complex(GO:0016342) |
| 0.0 | 2.1 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.3 | 1.8 | GO:0097513 | myosin II filament(GO:0097513) |
| 0.1 | 1.8 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.0 | 1.8 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.0 | 1.8 | GO:0031985 | Golgi cisterna(GO:0031985) |
| 0.4 | 1.6 | GO:0097454 | Schwann cell microvillus(GO:0097454) |
| 0.0 | 1.5 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 1.5 | GO:0098852 | lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852) |
| 0.5 | 1.4 | GO:1990851 | Wnt-Frizzled-LRP5/6 complex(GO:1990851) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 487 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 17.4 | GO:0003700 | nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700) |
| 0.2 | 5.0 | GO:0045295 | gamma-catenin binding(GO:0045295) |
| 0.1 | 5.0 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.2 | 4.6 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.0 | 4.6 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.1 | 4.4 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 0.1 | 4.3 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.2 | 3.7 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.3 | 3.4 | GO:0038191 | neuropilin binding(GO:0038191) |
| 0.1 | 3.2 | GO:0005351 | sugar:proton symporter activity(GO:0005351) |
| 0.0 | 3.2 | GO:0008174 | mRNA methyltransferase activity(GO:0008174) |
| 0.0 | 3.2 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.4 | 3.1 | GO:0046790 | virion binding(GO:0046790) |
| 0.1 | 2.9 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.2 | 2.8 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
| 0.2 | 2.6 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 0.1 | 2.3 | GO:0035497 | cAMP response element binding(GO:0035497) |
| 0.1 | 2.3 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.0 | 2.2 | GO:0046332 | SMAD binding(GO:0046332) |
| 0.1 | 2.1 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
