Motif ID: Pparg_Rxrg

Z-value: 0.961

Transcription factors associated with Pparg_Rxrg:

Gene SymbolEntrez IDGene Name
Pparg ENSMUSG00000000440.6 Pparg
Rxrg ENSMUSG00000015843.4 Rxrg

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rxrgmm10_v2_chr1_+_167618246_1676183090.369.1e-02Click!


Activity profile for motif Pparg_Rxrg.

activity profile for motif Pparg_Rxrg


Sorted Z-values histogram for motif Pparg_Rxrg

Sorted Z-values for motif Pparg_Rxrg



Network of associatons between targets according to the STRING database.



First level regulatory network of Pparg_Rxrg

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_126556128 3.466 ENSMUST00000141482.2
 Slc27a2
solute carrier family 27 (fatty acid transporter), member 2
chr7_+_4925802 3.138 ENSMUST00000057612.7
 Ssc5d
scavenger receptor cysteine rich domain containing (5 domains)
chr11_-_100759942 2.888 ENSMUST00000107363.2
 Kcnh4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr12_+_109452833 2.238 ENSMUST00000056110.8
 Dlk1
delta-like 1 homolog (Drosophila)
chr9_+_118506226 2.066 ENSMUST00000084820.4
 Golga4
golgi autoantigen, golgin subfamily a, 4
chr3_+_87948666 1.711 ENSMUST00000005019.5
 Crabp2
cellular retinoic acid binding protein II
chr2_-_180104463 1.699 ENSMUST00000056480.3
 Hrh3
histamine receptor H3
chr4_+_126556994 1.440 ENSMUST00000147675.1
 Clspn
claspin
chr14_-_21989475 1.434 ENSMUST00000043409.7
 Zfp503
zinc finger protein 503
chr1_-_138847579 1.409 ENSMUST00000093486.3
ENSMUST00000046870.6
 Lhx9

LIM homeobox protein 9

chr6_+_7844806 1.377 ENSMUST00000040159.4
 C1galt1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr6_+_34354119 1.270 ENSMUST00000038406.6
 Akr1b8
aldo-keto reductase family 1, member B8
chr11_-_100354040 1.244 ENSMUST00000173630.1
 Hap1
huntingtin-associated protein 1
chr11_+_23666479 1.235 ENSMUST00000143117.1
 Pus10
pseudouridylate synthase 10
chr2_-_117342831 1.229 ENSMUST00000178884.1
 Rasgrp1
RAS guanyl releasing protein 1
chr14_+_54476100 1.204 ENSMUST00000164766.1
ENSMUST00000164697.1
 Rem2

rad and gem related GTP binding protein 2

chr9_-_37552904 1.110 ENSMUST00000065668.5
 Nrgn
neurogranin
chr7_-_142899985 1.001 ENSMUST00000000219.3
 Th
tyrosine hydroxylase
chr4_+_126556935 0.995 ENSMUST00000048391.8
 Clspn
claspin
chr2_+_165595009 0.990 ENSMUST00000088132.6
 Eya2
eyes absent 2 homolog (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 259 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.2 3.5 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.6 3.1 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.2 2.6 GO:0000042 protein targeting to Golgi(GO:0000042)
0.3 2.4 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 2.1 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.3 1.9 GO:0098700 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
0.1 1.9 GO:0001522 pseudouridine synthesis(GO:0001522)
0.6 1.7 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.2 1.7 GO:0016576 histone dephosphorylation(GO:0016576)
0.2 1.7 GO:0042573 retinoic acid metabolic process(GO:0042573)
0.1 1.7 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.5 1.5 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578)
0.5 1.4 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.5 1.4 GO:1904685 positive regulation of metalloendopeptidase activity(GO:1904685)
0.3 1.4 GO:0035262 gonad morphogenesis(GO:0035262)
0.3 1.4 GO:0016266 O-glycan processing(GO:0016266)
0.4 1.3 GO:0016095 polyprenol catabolic process(GO:0016095) terpenoid catabolic process(GO:0016115) primary alcohol catabolic process(GO:0034310)
0.4 1.3 GO:0097623 potassium ion export across plasma membrane(GO:0097623)
0.1 1.3 GO:1900273 positive regulation of long-term synaptic potentiation(GO:1900273)
0.3 1.2 GO:0032901 positive regulation of neurotrophin production(GO:0032901)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 88 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.8 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 2.7 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 2.5 GO:0005814 centriole(GO:0005814)
0.0 2.1 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 1.9 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.2 1.2 GO:0097149 centralspindlin complex(GO:0097149)
0.0 1.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 1.1 GO:0044327 dendritic spine head(GO:0044327)
0.1 1.1 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 1.1 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 1.0 GO:0031045 dense core granule(GO:0031045)
0.1 0.9 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 0.8 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.7 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 0.7 GO:0030057 desmosome(GO:0030057)
0.0 0.7 GO:0030673 axolemma(GO:0030673)
0.2 0.6 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.1 0.6 GO:0097450 astrocyte end-foot(GO:0097450)
0.1 0.6 GO:0098536 deuterosome(GO:0098536)
0.1 0.6 GO:0032982 myosin filament(GO:0032982)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 157 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 4.4 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.2 3.1 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 3.1 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.4 2.4 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 2.4 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.4 2.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.2 1.9 GO:0034951 pivalyl-CoA mutase activity(GO:0034784) o-hydroxylaminobenzoate mutase activity(GO:0034951) lupeol synthase activity(GO:0042299) beta-amyrin synthase activity(GO:0042300) baruol synthase activity(GO:0080011)
0.2 1.5 GO:0070991 medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
0.2 1.5 GO:0001972 retinoic acid binding(GO:0001972)
0.1 1.5 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 1.5 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.1 1.4 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.1 1.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.4 1.3 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.2 1.3 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 1.3 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 1.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.2 1.1 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.1 1.1 GO:0004889 acetylcholine-activated cation-selective channel activity(GO:0004889) acetylcholine binding(GO:0042166)
0.1 1.1 GO:0070300 phosphatidic acid binding(GO:0070300)