Motif ID: Ppard

Z-value: 0.294


Transcription factors associated with Ppard:

Gene SymbolEntrez IDGene Name
Ppard ENSMUSG00000002250.9 Ppard

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ppardmm10_v2_chr17_+_28272191_28272205-0.538.9e-03Click!


Activity profile for motif Ppard.

activity profile for motif Ppard


Sorted Z-values histogram for motif Ppard

Sorted Z-values for motif Ppard



Network of associatons between targets according to the STRING database.



First level regulatory network of Ppard

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_87948666 1.132 ENSMUST00000005019.5
 Crabp2
cellular retinoic acid binding protein II
chr4_+_59581645 0.511 ENSMUST00000107528.1
 Hsdl2
hydroxysteroid dehydrogenase like 2
chr4_+_59581563 0.509 ENSMUST00000030078.5
 Hsdl2
hydroxysteroid dehydrogenase like 2
chr4_+_118429701 0.392 ENSMUST00000067896.3
 Elovl1
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1
chr16_+_84835070 0.343 ENSMUST00000009120.7
 Gabpa
GA repeat binding protein, alpha
chr1_+_178319130 0.300 ENSMUST00000027781.6
 Cox20
COX20 Cox2 chaperone
chr5_-_31697598 0.292 ENSMUST00000031018.7
 Rbks
ribokinase
chr2_+_75832168 0.264 ENSMUST00000047232.7
ENSMUST00000111952.2
 Agps

alkylglycerone phosphate synthase

chr11_+_98446826 0.252 ENSMUST00000019456.4
 Grb7
growth factor receptor bound protein 7
chr10_+_94147982 0.249 ENSMUST00000105290.2
 Nr2c1
nuclear receptor subfamily 2, group C, member 1
chr9_+_118506226 0.241 ENSMUST00000084820.4
 Golga4
golgi autoantigen, golgin subfamily a, 4
chr6_+_7844806 0.236 ENSMUST00000040159.4
 C1galt1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr9_-_107872821 0.232 ENSMUST00000183032.1
 Rbm6
RNA binding motif protein 6
chr9_-_107872687 0.226 ENSMUST00000035201.6
 Rbm6
RNA binding motif protein 6
chr1_-_55088024 0.217 ENSMUST00000027123.8
 Hspd1
heat shock protein 1 (chaperonin)
chr10_-_13324160 0.207 ENSMUST00000105545.4
 Phactr2
phosphatase and actin regulator 2
chr11_+_70657687 0.200 ENSMUST00000134087.1
ENSMUST00000170716.1
 Eno3

enolase 3, beta muscle

chr4_+_148602527 0.193 ENSMUST00000105701.2
ENSMUST00000052060.6
 Masp2

mannan-binding lectin serine peptidase 2

chr10_+_58255465 0.182 ENSMUST00000057659.7
ENSMUST00000162041.1
ENSMUST00000162860.1
 Gcc2


GRIP and coiled-coil domain containing 2


chr19_+_37207528 0.179 ENSMUST00000024078.7
ENSMUST00000112391.1
 March5

membrane-associated ring finger (C3HC4) 5

chr9_+_108392820 0.170 ENSMUST00000035234.4
 1700102P08Rik
RIKEN cDNA 1700102P08 gene
chr5_-_115119277 0.170 ENSMUST00000031524.7
 Acads
acyl-Coenzyme A dehydrogenase, short chain
chr3_-_79628660 0.152 ENSMUST00000120992.1
 Etfdh
electron transferring flavoprotein, dehydrogenase
chr16_+_84834901 0.152 ENSMUST00000114184.1
 Gabpa
GA repeat binding protein, alpha
chr9_+_107340593 0.143 ENSMUST00000042581.2
 6430571L13Rik
RIKEN cDNA 6430571L13 gene
chr9_-_107872403 0.136 ENSMUST00000183035.1
 Rbm6
RNA binding motif protein 6
chr6_+_83156401 0.134 ENSMUST00000032106.4
 1700003E16Rik
RIKEN cDNA 1700003E16 gene
chr9_-_22002599 0.129 ENSMUST00000115336.2
ENSMUST00000044926.5
 Ccdc151

coiled-coil domain containing 151

chr4_-_41048124 0.126 ENSMUST00000030136.6
 Aqp7
aquaporin 7
chr4_-_155043143 0.123 ENSMUST00000135665.2
 Plch2
phospholipase C, eta 2
chr2_+_154436437 0.123 ENSMUST00000109725.1
ENSMUST00000099178.3
ENSMUST00000045270.8
ENSMUST00000109724.1
 Cbfa2t2



core-binding factor, runt domain, alpha subunit 2, translocated to, 2 (human)



chr8_-_111393810 0.122 ENSMUST00000038475.8
 Fa2h
fatty acid 2-hydroxylase
chr15_-_50890396 0.117 ENSMUST00000185183.1
 Trps1
trichorhinophalangeal syndrome I (human)
chr17_+_52602700 0.112 ENSMUST00000039366.10
 Kcnh8
potassium voltage-gated channel, subfamily H (eag-related), member 8
chr11_-_70015346 0.110 ENSMUST00000018718.7
ENSMUST00000102574.3
 Acadvl

acyl-Coenzyme A dehydrogenase, very long chain

chr3_-_138131356 0.106 ENSMUST00000029805.8
 Mttp
microsomal triglyceride transfer protein
chr8_+_117095854 0.099 ENSMUST00000034308.8
ENSMUST00000167370.1
ENSMUST00000176860.1
 Bcmo1


beta-carotene 15,15'-monooxygenase


chrX_-_142306170 0.098 ENSMUST00000134825.2
 Kcne1l
potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene
chr1_-_55088156 0.096 ENSMUST00000127861.1
ENSMUST00000144077.1
 Hspd1

heat shock protein 1 (chaperonin)

chr7_+_82648595 0.096 ENSMUST00000141726.1
ENSMUST00000179489.1
ENSMUST00000039881.3
 Eftud1


elongation factor Tu GTP binding domain containing 1


chr12_-_40223149 0.093 ENSMUST00000171553.1
ENSMUST00000001672.5
 Ifrd1

interferon-related developmental regulator 1

chr15_-_102189032 0.092 ENSMUST00000023805.1
 Csad
cysteine sulfinic acid decarboxylase
chr4_+_118409331 0.073 ENSMUST00000084319.4
ENSMUST00000106384.3
ENSMUST00000126089.1
ENSMUST00000073881.1
ENSMUST00000019229.8
ENSMUST00000144577.1
 Med8





mediator of RNA polymerase II transcription, subunit 8 homolog (yeast)





chr9_+_46012810 0.071 ENSMUST00000126865.1
 Sik3
SIK family kinase 3
chr13_-_86046901 0.057 ENSMUST00000131011.1
 Cox7c
cytochrome c oxidase subunit VIIc
chr17_-_34028044 0.057 ENSMUST00000045467.7
ENSMUST00000114303.3
 H2-Ke6

H2-K region expressed gene 6

chr4_-_45108038 0.056 ENSMUST00000107809.2
ENSMUST00000107808.2
ENSMUST00000107807.1
ENSMUST00000107810.2
 Tomm5



translocase of outer mitochondrial membrane 5 homolog (yeast)



chr5_-_110286159 0.055 ENSMUST00000031472.5
 Pxmp2
peroxisomal membrane protein 2
chr7_+_141468776 0.048 ENSMUST00000058746.5
 Cd151
CD151 antigen
chr5_+_129725063 0.047 ENSMUST00000086046.3
 Gbas
glioblastoma amplified sequence
chr4_+_131873608 0.044 ENSMUST00000053819.3
 Srsf4
serine/arginine-rich splicing factor 4
chr4_+_98546919 0.042 ENSMUST00000030290.7
 Inadl
InaD-like (Drosophila)
chr7_-_89338709 0.042 ENSMUST00000137723.1
ENSMUST00000117852.1
ENSMUST00000041968.3
 Tmem135


transmembrane protein 135


chr10_-_93589621 0.042 ENSMUST00000020203.6
 Snrpf
small nuclear ribonucleoprotein polypeptide F
chr4_+_98546710 0.041 ENSMUST00000102792.3
 Inadl
InaD-like (Drosophila)
chr2_-_73911323 0.040 ENSMUST00000111996.1
ENSMUST00000018914.2
 Atp5g3

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)

chr1_-_120120138 0.040 ENSMUST00000112648.1
ENSMUST00000128408.1
 Dbi

diazepam binding inhibitor

chr3_-_79628859 0.039 ENSMUST00000029386.7
 Etfdh
electron transferring flavoprotein, dehydrogenase
chr16_-_84835557 0.037 ENSMUST00000138279.1
ENSMUST00000023608.7
 Atp5j

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F

chr3_+_90051630 0.028 ENSMUST00000159064.1
 4933434E20Rik
RIKEN cDNA 4933434E20 gene
chr1_+_55088132 0.026 ENSMUST00000075242.6
 Hspe1
heat shock protein 1 (chaperonin 10)
chr15_-_89425856 0.023 ENSMUST00000109313.2
 Cpt1b
carnitine palmitoyltransferase 1b, muscle
chr2_-_26237368 0.016 ENSMUST00000036187.8
 Qsox2
quiescin Q6 sulfhydryl oxidase 2
chr16_-_84835484 0.008 ENSMUST00000114191.1
 Atp5j
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0002842 T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) positive regulation of T cell mediated immune response to tumor cell(GO:0002842)
0.1 1.1 GO:0042573 retinoic acid metabolic process(GO:0042573) positive regulation of collateral sprouting(GO:0048672)
0.0 0.2 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.3 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.4 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0015793 glycerol transport(GO:0015793)
0.0 0.2 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.0 0.2 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.3 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.5 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.1 GO:0099624 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372) atrial cardiac muscle cell membrane repolarization(GO:0099624)
0.0 0.1 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.2 GO:0046459 short-chain fatty acid metabolic process(GO:0046459)
0.0 0.1 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.2 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.1 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.0 0.0 GO:2000983 regulation of ATP citrate synthase activity(GO:2000983) negative regulation of ATP citrate synthase activity(GO:2000984)
0.0 0.1 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.1 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.0 0.1 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.0 0.2 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.3 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.2 GO:0006958 complement activation, classical pathway(GO:0006958)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.2 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.0 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0019841 retinol binding(GO:0019841)
0.1 0.2 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.3 GO:0043559 insulin binding(GO:0043559)
0.0 0.4 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 1.1 GO:0008748 N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) epoxyqueuosine reductase activity(GO:0052693)
0.0 0.2 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.1 GO:0015265 urea channel activity(GO:0015265)
0.0 0.1 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 0.2 GO:0001846 opsonin binding(GO:0001846)
0.0 0.1 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0 0.2 GO:0052890 acyl-CoA dehydrogenase activity(GO:0003995) oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor(GO:0052890)
0.0 0.0 GO:0030156 benzodiazepine receptor binding(GO:0030156)