Motif ID: Hoxb7

Z-value: 2.388


Transcription factors associated with Hoxb7:

Gene SymbolEntrez IDGene Name
Hoxb7 ENSMUSG00000038721.8 Hoxb7



Activity profile for motif Hoxb7.

activity profile for motif Hoxb7


Sorted Z-values histogram for motif Hoxb7

Sorted Z-values for motif Hoxb7



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxb7

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_6730051 11.424 ENSMUST00000043578.6
ENSMUST00000131467.1
ENSMUST00000150761.1
ENSMUST00000151281.1
 St18



suppression of tumorigenicity 18



chr3_+_55782500 11.302 ENSMUST00000075422.4
 Mab21l1
mab-21-like 1 (C. elegans)
chr13_+_94875600 8.591 ENSMUST00000022195.10
 Otp
orthopedia homolog (Drosophila)
chr6_+_15196949 8.519 ENSMUST00000151301.1
ENSMUST00000131414.1
ENSMUST00000140557.1
ENSMUST00000115469.1
 Foxp2



forkhead box P2



chr4_+_13751297 8.343 ENSMUST00000105566.2
 Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr16_-_26989974 7.512 ENSMUST00000089832.4
 Gmnc
geminin coiled-coil domain containing
chr12_+_38783455 6.743 ENSMUST00000161980.1
ENSMUST00000160701.1
 Etv1

ets variant gene 1

chr13_-_40730416 6.478 ENSMUST00000021787.5
 Tfap2a
transcription factor AP-2, alpha
chr6_-_23248264 6.448 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr12_+_38783503 6.125 ENSMUST00000159334.1
 Etv1
ets variant gene 1
chr1_+_6734827 6.106 ENSMUST00000139838.1
 St18
suppression of tumorigenicity 18
chr14_+_75455957 5.869 ENSMUST00000164848.1
 Siah3
seven in absentia homolog 3 (Drosophila)
chr2_+_65930117 5.826 ENSMUST00000176109.1
 Csrnp3
cysteine-serine-rich nuclear protein 3
chr15_-_56694525 5.741 ENSMUST00000050544.7
 Has2
hyaluronan synthase 2
chrX_-_43167817 5.713 ENSMUST00000115058.1
ENSMUST00000115059.1
 Tenm1

teneurin transmembrane protein 1

chr5_-_53707532 5.489 ENSMUST00000031093.3
 Cckar
cholecystokinin A receptor
chr3_+_102010138 5.452 ENSMUST00000066187.4
 Nhlh2
nescient helix loop helix 2
chr5_+_139543889 5.212 ENSMUST00000174792.1
ENSMUST00000031523.8
 Uncx

UNC homeobox

chr12_-_31713873 5.015 ENSMUST00000057783.4
ENSMUST00000174480.2
ENSMUST00000176710.1
 Gpr22


G protein-coupled receptor 22


chr7_-_70366735 4.898 ENSMUST00000089565.5
 Nr2f2
nuclear receptor subfamily 2, group F, member 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 417 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 22.0 GO:0006376 mRNA splice site selection(GO:0006376)
1.1 15.9 GO:0060013 righting reflex(GO:0060013)
0.2 14.4 GO:0001578 microtubule bundle formation(GO:0001578)
1.2 13.2 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
1.3 11.7 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.2 10.6 GO:0043488 regulation of mRNA stability(GO:0043488)
0.5 10.4 GO:0007638 mechanosensory behavior(GO:0007638)
3.1 9.4 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.5 9.2 GO:0008090 retrograde axonal transport(GO:0008090)
1.1 8.9 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
2.9 8.7 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
0.4 8.4 GO:0060216 definitive hemopoiesis(GO:0060216)
0.2 8.1 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.2 7.8 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.3 7.6 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.2 7.6 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.2 7.5 GO:0006270 DNA replication initiation(GO:0006270)
2.5 7.4 GO:0090274 positive regulation of somatostatin secretion(GO:0090274)
0.1 7.4 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
1.1 6.8 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 172 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 125.3 GO:0005634 nucleus(GO:0005634)
0.2 15.9 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.6 14.7 GO:0033270 paranode region of axon(GO:0033270)
0.4 14.6 GO:0043034 costamere(GO:0043034)
1.0 12.5 GO:0042788 polysomal ribosome(GO:0042788)
0.2 11.0 GO:0044295 axonal growth cone(GO:0044295)
1.1 10.3 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 9.8 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 8.8 GO:0043195 terminal bouton(GO:0043195)
2.0 7.9 GO:0031673 H zone(GO:0031673)
0.1 7.5 GO:0016363 nuclear matrix(GO:0016363)
0.5 7.1 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 6.2 GO:0030427 site of polarized growth(GO:0030427)
0.6 5.8 GO:0030478 actin cap(GO:0030478)
1.7 5.2 GO:0032437 cuticular plate(GO:0032437)
0.3 5.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.2 5.1 GO:0032809 neuronal cell body membrane(GO:0032809)
0.3 4.8 GO:0031045 dense core granule(GO:0031045)
0.1 4.2 GO:0032420 stereocilium(GO:0032420)
0.1 4.0 GO:0042734 presynaptic membrane(GO:0042734)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 255 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 37.8 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.8 23.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 21.1 GO:0044822 poly(A) RNA binding(GO:0044822)
0.1 15.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
1.8 14.1 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.6 12.9 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 11.1 GO:0017124 SH3 domain binding(GO:0017124)
0.4 10.8 GO:0017091 AU-rich element binding(GO:0017091)
0.1 10.8 GO:0008017 microtubule binding(GO:0008017)
0.3 10.6 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 10.6 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 10.4 GO:0061659 ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
1.4 9.9 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.2 9.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 9.2 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
1.3 8.9 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.4 8.5 GO:0031402 sodium ion binding(GO:0031402)
0.6 7.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.2 6.9 GO:0070888 E-box binding(GO:0070888)
0.1 6.3 GO:0005496 steroid binding(GO:0005496)