Motif ID: Pax3

Z-value: 0.338


Transcription factors associated with Pax3:

Gene SymbolEntrez IDGene Name
Pax3 ENSMUSG00000004872.9 Pax3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pax3mm10_v2_chr1_-_78196832_781968450.538.9e-03Click!


Activity profile for motif Pax3.

activity profile for motif Pax3


Sorted Z-values histogram for motif Pax3

Sorted Z-values for motif Pax3



Network of associatons between targets according to the STRING database.



First level regulatory network of Pax3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_+_38781093 0.830 ENSMUST00000161513.1
 Etv1
ets variant gene 1
chr12_+_38780817 0.634 ENSMUST00000160856.1
 Etv1
ets variant gene 1
chr12_+_38780284 0.614 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
 Etv1


ets variant gene 1


chr12_+_109747903 0.595 ENSMUST00000183084.1
ENSMUST00000182300.1
 Mirg

miRNA containing gene

chr10_-_70592782 0.454 ENSMUST00000162251.1
 Phyhipl
phytanoyl-CoA hydroxylase interacting protein-like
chr4_+_127077374 0.422 ENSMUST00000046751.6
ENSMUST00000094713.3
 Zmym6

zinc finger, MYM-type 6

chr14_+_51893610 0.421 ENSMUST00000047726.5
ENSMUST00000161888.1
 Slc39a2

solute carrier family 39 (zinc transporter), member 2

chr17_+_21691860 0.419 ENSMUST00000072133.4
 Gm10226
predicted gene 10226
chr2_+_102659213 0.405 ENSMUST00000111213.1
 Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr2_-_136387929 0.387 ENSMUST00000035264.2
ENSMUST00000077200.3
 Pak7

p21 protein (Cdc42/Rac)-activated kinase 7

chr12_+_52699297 0.385 ENSMUST00000095737.3
 Akap6
A kinase (PRKA) anchor protein 6
chr8_+_33428709 0.377 ENSMUST00000059351.7
 5930422O12Rik
RIKEN cDNA 5930422O12 gene
chrX_-_103623648 0.349 ENSMUST00000156211.1
 Ftx
Ftx transcript, Xist regulator (non-protein coding)
chr12_+_109540979 0.345 ENSMUST00000129245.1
ENSMUST00000143836.1
ENSMUST00000124106.1
 Meg3


maternally expressed 3


chr7_+_30121915 0.323 ENSMUST00000098596.3
ENSMUST00000153792.1
 Zfp382

zinc finger protein 382

chr10_+_82138253 0.305 ENSMUST00000105314.2
 AU041133
expressed sequence AU041133
chr16_-_88056176 0.291 ENSMUST00000072256.5
ENSMUST00000023652.8
ENSMUST00000114137.1
 Grik1


glutamate receptor, ionotropic, kainate 1


chr4_-_25281801 0.265 ENSMUST00000102994.3
 Ufl1
UFM1 specific ligase 1
chrX_-_103623704 0.248 ENSMUST00000130063.1
ENSMUST00000125419.1
 Ftx

Ftx transcript, Xist regulator (non-protein coding)

chrX_+_114474312 0.245 ENSMUST00000113371.1
ENSMUST00000040504.5
 Klhl4

kelch-like 4

chr4_-_25281752 0.235 ENSMUST00000038705.7
 Ufl1
UFM1 specific ligase 1
chr3_+_36159522 0.228 ENSMUST00000165956.2
 D3Ertd254e
DNA segment, Chr 3, ERATO Doi 254, expressed
chr16_+_32877775 0.197 ENSMUST00000023489.4
ENSMUST00000171325.1
 Fyttd1

forty-two-three domain containing 1

chr13_+_24327415 0.176 ENSMUST00000167746.1
 Cmah
cytidine monophospho-N-acetylneuraminic acid hydroxylase
chr18_+_35562158 0.148 ENSMUST00000166793.1
 Matr3
matrin 3
chr17_+_87107621 0.132 ENSMUST00000041369.6
 Socs5
suppressor of cytokine signaling 5
chr8_+_71887264 0.107 ENSMUST00000034259.7
 Zfp709
zinc finger protein 709
chr13_+_14630237 0.105 ENSMUST00000178289.1
ENSMUST00000038690.4
 AW209491

expressed sequence AW209491

chr4_+_11486002 0.070 ENSMUST00000108307.2
 1110037F02Rik
RIKEN cDNA 1110037F02 gene
chr1_+_87404916 0.052 ENSMUST00000173152.1
ENSMUST00000173663.1
 Gigyf2

GRB10 interacting GYF protein 2

chr4_+_3940747 0.038 ENSMUST00000119403.1
 Chchd7
coiled-coil-helix-coiled-coil-helix domain containing 7
chr1_+_176814660 0.020 ENSMUST00000056773.8
ENSMUST00000027785.8
 Sdccag8

serologically defined colon cancer antigen 8

chr9_+_64235201 0.003 ENSMUST00000039011.3
 Uchl4
ubiquitin carboxyl-terminal esterase L4
chr11_+_70970467 0.002 ENSMUST00000178822.1
ENSMUST00000108529.3
ENSMUST00000169965.1
ENSMUST00000167509.1
 Rpain



RPA interacting protein



chr3_+_79884496 0.001 ENSMUST00000118853.1
 Fam198b
family with sequence similarity 198, member B

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.1 0.4 GO:0032512 regulation of protein phosphatase type 2B activity(GO:0032512) positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.1 0.5 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 0.4 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 2.1 GO:0007638 mechanosensory behavior(GO:0007638)
0.1 0.2 GO:0046381 CMP-N-acetylneuraminate metabolic process(GO:0046381)
0.0 0.3 GO:0032229 positive regulation of gamma-aminobutyric acid secretion(GO:0014054) negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.0 0.1 GO:0071638 positive regulation of T-helper 1 cell differentiation(GO:0045627) negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.3 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.4 GO:0006829 zinc II ion transport(GO:0006829)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.4 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.4 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0071568 UFM1 transferase activity(GO:0071568)
0.1 0.4 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.2 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 0.3 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.4 GO:0043495 protein anchor(GO:0043495)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)